JP6646579B2 - 高アンモニア血症の検出のためのデバイス及びデバイスを使用する方法 - Google Patents

高アンモニア血症の検出のためのデバイス及びデバイスを使用する方法 Download PDF

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JP6646579B2
JP6646579B2 JP2016537941A JP2016537941A JP6646579B2 JP 6646579 B2 JP6646579 B2 JP 6646579B2 JP 2016537941 A JP2016537941 A JP 2016537941A JP 2016537941 A JP2016537941 A JP 2016537941A JP 6646579 B2 JP6646579 B2 JP 6646579B2
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ammonia
sample
biosensor
indophenol
concentration
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JP2016529515A5 (enExample
JP2016529515A (ja
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オマール ビラル アユブ,
オマール ビラル アユブ,
アダム マイケル ベーレンス,
アダム マイケル ベーレンス,
ピーター コフィナス,
ピーター コフィナス,
マーシャル リン サマー,
マーシャル リン サマー,
フアン マヌエル カブレラ−ルケ,
フアン マヌエル カブレラ−ルケ,
ゲイリー カニンガム,
ゲイリー カニンガム,
アントン シメオノフ,
アントン シメオノフ,
フアン マルガン,
フアン マルガン,
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Childrens National Medical Center Inc
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Childrens National Medical Center Inc
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/487Physical analysis of biological material of liquid biological material
    • G01N33/49Blood
    • G01N33/4925Blood measuring blood gas content, e.g. O2, CO2, HCO3
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01JMEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/28Investigating the spectrum
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28Electrolytic cell components
    • G01N27/30Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28Electrolytic cell components
    • G01N27/30Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3275Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/84Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving inorganic compounds or pH
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/78Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/04Endocrine or metabolic disorders

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Ecology (AREA)
  • Biophysics (AREA)
  • Inorganic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Plasma & Fusion (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
JP2016537941A 2013-08-30 2014-09-02 高アンモニア血症の検出のためのデバイス及びデバイスを使用する方法 Active JP6646579B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361872149P 2013-08-30 2013-08-30
US61/872,149 2013-08-30
PCT/US2014/053756 WO2015031911A1 (en) 2013-08-30 2014-09-02 Device and methods of using device for detection of hyperammonemia

Publications (3)

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JP2016529515A JP2016529515A (ja) 2016-09-23
JP2016529515A5 JP2016529515A5 (enExample) 2017-10-19
JP6646579B2 true JP6646579B2 (ja) 2020-02-14

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JP2016537941A Active JP6646579B2 (ja) 2013-08-30 2014-09-02 高アンモニア血症の検出のためのデバイス及びデバイスを使用する方法

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US (2) US9952199B2 (enExample)
EP (2) EP3039422B1 (enExample)
JP (1) JP6646579B2 (enExample)
KR (1) KR102278346B1 (enExample)
CN (1) CN105940300B (enExample)
AU (1) AU2014311977B2 (enExample)
BR (1) BR112016004320B1 (enExample)
CA (1) CA2922821C (enExample)
CL (1) CL2016000467A1 (enExample)
DK (2) DK3540429T3 (enExample)
IL (1) IL244274B (enExample)
MX (1) MX2016002632A (enExample)
SA (1) SA516370640B1 (enExample)
TR (1) TR201903528T4 (enExample)
WO (1) WO2015031911A1 (enExample)

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US10792339B2 (en) 2015-07-17 2020-10-06 Children's National Medical Center Methods and compositions for treating phenylketonuria
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US20220364076A1 (en) * 2019-07-02 2022-11-17 The Texas A&M University System Microfluidic platform for selective exosome isolation
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CN110806448B (zh) * 2019-11-21 2022-03-22 北京市药品检验所 测定复方氨基酸注射液中游离氨的方法
KR102369697B1 (ko) * 2020-05-18 2022-03-03 국민대학교산학협력단 바이오 센싱 모듈, 바이오 센싱 장치, 및 이를 포함하는 바이오 센싱 시스템
WO2022008714A1 (en) * 2020-07-10 2022-01-13 Radiometer Medical Aps A blood gas analyzer and a system comprising a blood gas analyzer, and use thereof
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US20250000957A1 (en) * 2021-09-16 2025-01-02 Arcturus Therapeutics, Inc. Compositions and methods for treating phenylketonuria
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CN114088026B (zh) * 2022-01-20 2022-04-05 江苏奥琳斯邦装备科技股份有限公司 一种应变测量的热压固化装置以及固化方法
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Also Published As

Publication number Publication date
CL2016000467A1 (es) 2016-10-28
US20180284099A1 (en) 2018-10-04
EP3039422B1 (en) 2019-01-09
DK3540429T3 (da) 2021-02-15
US9952199B2 (en) 2018-04-24
EP3540429A1 (en) 2019-09-18
IL244274A0 (en) 2016-04-21
IL244274B (en) 2020-09-30
CN105940300B (zh) 2019-01-22
KR20160048204A (ko) 2016-05-03
EP3540429B1 (en) 2020-11-11
US10620187B2 (en) 2020-04-14
BR112016004320A2 (pt) 2017-10-24
JP2016529515A (ja) 2016-09-23
EP3039422A4 (en) 2017-04-19
BR112016004320B1 (pt) 2022-03-03
TR201903528T4 (tr) 2019-04-22
AU2014311977B2 (en) 2019-02-21
KR102278346B1 (ko) 2021-07-19
AU2014311977A1 (en) 2016-03-17
CN105940300A (zh) 2016-09-14
SA516370640B1 (ar) 2019-02-24
CA2922821C (en) 2023-01-03
CA2922821A1 (en) 2015-03-05
WO2015031911A1 (en) 2015-03-05
US20160231310A1 (en) 2016-08-11
MX2016002632A (es) 2016-10-04
DK3039422T3 (en) 2019-03-25
EP3039422A1 (en) 2016-07-06

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