RU94044342A - Биоабсорбируемое хирургическое гемостатическое средство и способы его получения - Google Patents

Биоабсорбируемое хирургическое гемостатическое средство и способы его получения

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Publication number
RU94044342A
RU94044342A RU94044342/14A RU94044342A RU94044342A RU 94044342 A RU94044342 A RU 94044342A RU 94044342/14 A RU94044342/14 A RU 94044342/14A RU 94044342 A RU94044342 A RU 94044342A RU 94044342 A RU94044342 A RU 94044342A
Authority
RU
Russia
Prior art keywords
modified
calcium
agent
oxidized cellulose
hemostatic agent
Prior art date
Application number
RU94044342/14A
Other languages
English (en)
Other versions
RU2136319C1 (ru
Inventor
Л.Стилуэлл Реджинальд
Us]
Дж.Уитмор Илэйн
Дж.Сэйферстейн Лоуэлл
Original Assignee
Джонсон энд Джонсон Медикал
Джонсон энд Джонсон Медикал, Инк.
Инк. (US)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Джонсон энд Джонсон Медикал, Джонсон энд Джонсон Медикал, Инк., Инк. (US) filed Critical Джонсон энд Джонсон Медикал
Publication of RU94044342A publication Critical patent/RU94044342A/ru
Application granted granted Critical
Publication of RU2136319C1 publication Critical patent/RU2136319C1/ru

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/64—Use of materials characterised by their function or physical properties specially adapted to be resorbable inside the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/28—Polysaccharides or their derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L1/00—Compositions of cellulose, modified cellulose or cellulose derivatives
    • C08L1/02—Cellulose; Modified cellulose
    • C08L1/04—Oxycellulose; Hydrocellulose, e.g. microcrystalline cellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/04—Materials for stopping bleeding
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S602/00—Surgery: splint, brace, or bandage
    • Y10S602/90—Method of making bandage structure

Abstract

Модифицированное кальцием окисленное целлюлозное гемостатическое средство, обеспечивающее более быструю остановку кровотечения, чем немодифицированная или модифицированная натрием или калием окисленная целлюлоза. Весовой процент кальция в модифицированной окисленной целлюлозе должен быть в диапазоне примерно от 0,5 до 4, чтобы усиливать гемостатические свойства и при этом не наносить чрезмерного ущерба биоабсорбируемости. Во втором варианте окисленное целлюлозное гемостатическое средство модифицируют кальцием и натрием или калием. Второй вариант можно использовать для доставки материалов, чувствительных к кислотам.

Claims (1)

  1. Модифицированное кальцием окисленное целлюлозное гемостатическое средство, обеспечивающее более быструю остановку кровотечения, чем немодифицированная или модифицированная натрием или калием окисленная целлюлоза. Весовой процент кальция в модифицированной окисленной целлюлозе должен быть в диапазоне примерно от 0,5 до 4, чтобы усиливать гемостатические свойства и при этом не наносить чрезмерного ущерба биоабсорбируемости. Во втором варианте окисленное целлюлозное гемостатическое средство модифицируют кальцием и натрием или калием. Второй вариант можно использовать для доставки материалов, чувствительных к кислотам.
RU94044342A 1993-12-23 1994-12-20 Биоабсорбируемое хирургическое гемостатическое средство и способ его получения (варианты) RU2136319C1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17332593A 1993-12-23 1993-12-23
US08/173,325 1993-12-23

Publications (2)

Publication Number Publication Date
RU94044342A true RU94044342A (ru) 1996-10-20
RU2136319C1 RU2136319C1 (ru) 1999-09-10

Family

ID=22631515

Family Applications (1)

Application Number Title Priority Date Filing Date
RU94044342A RU2136319C1 (ru) 1993-12-23 1994-12-20 Биоабсорбируемое хирургическое гемостатическое средство и способ его получения (варианты)

Country Status (23)

Country Link
US (1) US5484913A (ru)
EP (1) EP0659440B1 (ru)
JP (1) JP3602178B2 (ru)
KR (1) KR950016789A (ru)
CN (1) CN1070704C (ru)
AT (1) ATE219949T1 (ru)
AU (1) AU677118B2 (ru)
BR (1) BR9405232A (ru)
CA (1) CA2138850C (ru)
CZ (1) CZ288792B6 (ru)
DE (2) DE659440T1 (ru)
DK (1) DK0659440T3 (ru)
ES (1) ES2080034T3 (ru)
FI (1) FI946038A (ru)
GR (1) GR950300073T1 (ru)
HU (1) HUT71587A (ru)
MY (1) MY131908A (ru)
NO (1) NO944986L (ru)
PL (1) PL178356B1 (ru)
PT (1) PT659440E (ru)
RU (1) RU2136319C1 (ru)
SG (1) SG75781A1 (ru)
ZA (1) ZA9410283B (ru)

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EP0659440B1 (en) 2002-07-03
PT659440E (pt) 2002-10-31
HUT71587A (en) 1995-12-28
AU8171894A (en) 1995-06-29
JPH07255830A (ja) 1995-10-09
NO944986L (no) 1995-06-26
HU9403781D0 (en) 1995-02-28
FI946038A (fi) 1995-06-24
ATE219949T1 (de) 2002-07-15
CN1109756A (zh) 1995-10-11
CZ324594A3 (en) 1995-10-18
KR950016789A (ko) 1995-07-20
CA2138850A1 (en) 1995-06-24
SG75781A1 (en) 2000-10-24
FI946038A0 (fi) 1994-12-22
BR9405232A (pt) 1995-08-01
CZ288792B6 (cs) 2001-09-12
US5484913A (en) 1996-01-16
CA2138850C (en) 2007-06-19
GR950300073T1 (en) 1996-01-31
ES2080034T1 (es) 1996-02-01
MY131908A (en) 2007-09-28
DE69430897D1 (de) 2002-08-08
EP0659440A1 (en) 1995-06-28
AU677118B2 (en) 1997-04-10
ES2080034T3 (es) 2003-01-01
JP3602178B2 (ja) 2004-12-15
DE69430897T2 (de) 2003-01-23
NO944986D0 (no) 1994-12-22
DE659440T1 (de) 1996-10-10
PL178356B1 (pl) 2000-04-28
PL306475A1 (en) 1995-06-26
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DK0659440T3 (da) 2002-10-14
RU2136319C1 (ru) 1999-09-10

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