RU93005051A - Способ получения катионных кристаллов гр или производных гр, катионные кристаллы человеческого гр или производных человеческого гр, фармацевтические препараты, использование процесса кристаллизации - Google Patents
Способ получения катионных кристаллов гр или производных гр, катионные кристаллы человеческого гр или производных человеческого гр, фармацевтические препараты, использование процесса кристаллизацииInfo
- Publication number
- RU93005051A RU93005051A RU93005051/13A RU93005051A RU93005051A RU 93005051 A RU93005051 A RU 93005051A RU 93005051/13 A RU93005051/13 A RU 93005051/13A RU 93005051 A RU93005051 A RU 93005051A RU 93005051 A RU93005051 A RU 93005051A
- Authority
- RU
- Russia
- Prior art keywords
- crystals
- derivative
- human
- cationic
- gramoproteins
- Prior art date
Links
- 125000002091 cationic group Chemical group 0.000 title 2
- 238000000034 method Methods 0.000 title 2
- 239000000825 pharmaceutical preparation Substances 0.000 title 1
- 239000000122 growth hormone Substances 0.000 claims 2
- 102000018997 Growth Hormone Human genes 0.000 claims 1
- 108010051696 Growth Hormone Proteins 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 238000002360 preparation method Methods 0.000 claims 1
Claims (1)
- Способ относится к получению химически стойких и биологически активных гормонов роста, а также фамацевтических препаратов, содержащих кристаллы гормонов роста.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK1687/90 | 1990-07-13 | ||
| DK168790A DK168790D0 (ru) | 1990-07-13 | 1990-07-13 | |
| PCT/DK1991/000203 WO1992000998A1 (en) | 1990-07-13 | 1991-07-12 | Growth hormone crystals and a process for production of these gh-crystals |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU93005051A true RU93005051A (ru) | 1996-04-20 |
| RU2108341C1 RU2108341C1 (ru) | 1998-04-10 |
Family
ID=8107212
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU93005051/13A RU2108341C1 (ru) | 1990-07-13 | 1991-07-12 | Способ получения кристаллов гр или производных гр, кристаллы человеческих гр или производных человеческих гр и фармацевтический препарат |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US6117984A (ru) |
| EP (1) | EP0540582B1 (ru) |
| JP (1) | JP2524446B2 (ru) |
| AT (1) | ATE110745T1 (ru) |
| AU (1) | AU666465B2 (ru) |
| BG (1) | BG61267B1 (ru) |
| CA (1) | CA2086087C (ru) |
| DE (1) | DE69103755T2 (ru) |
| DK (2) | DK168790D0 (ru) |
| ES (1) | ES2060399T3 (ru) |
| HU (2) | HUT64086A (ru) |
| IE (1) | IE67054B1 (ru) |
| NZ (1) | NZ238904A (ru) |
| PT (1) | PT98297B (ru) |
| RU (1) | RU2108341C1 (ru) |
| WO (1) | WO1992000998A1 (ru) |
| ZA (1) | ZA915446B (ru) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK168790D0 (ru) * | 1990-07-13 | 1990-07-13 | Novo Nordisk As | |
| US6894023B1 (en) * | 1990-07-13 | 2005-05-17 | Novo Nordisk A/S | Growth hormone crystals and a process for production of these GH-crystals |
| DE69233704T2 (de) * | 1991-12-20 | 2008-05-21 | Novo Nordisk A/S | Stabilisierte pharmazeutische Formulierung, umfassend Wachstumshormon und Histidin |
| SE9302278D0 (sv) * | 1992-10-28 | 1993-07-02 | Kabi Pharmacia Ab | Growth hormone |
| ATE233088T1 (de) | 1996-12-20 | 2003-03-15 | Takeda Chemical Industries Ltd | Verfahren zur herstellung einer zusammensetzung mit verzoegerter abgabe |
| US6541606B2 (en) | 1997-12-31 | 2003-04-01 | Altus Biologics Inc. | Stabilized protein crystals formulations containing them and methods of making them |
| JP3723857B2 (ja) * | 1998-02-04 | 2005-12-07 | 日本ケミカルリサーチ株式会社 | ヒト成長ホルモン含有水性医薬組成物 |
| US7101575B2 (en) | 1998-03-19 | 2006-09-05 | Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. | Production of nanocapsules and microcapsules by layer-wise polyelectrolyte self-assembly |
| US6451347B1 (en) | 1999-03-01 | 2002-09-17 | Alkermes Controlled Therapeutics, Inc. | Method for purifying human growth hormone |
| DE60000622T2 (de) * | 1999-06-10 | 2003-02-27 | Max Planck Gesellschaft | Einkapselung von kristallen mit mehrschichtigem überzug |
| US6566329B1 (en) | 1999-06-28 | 2003-05-20 | Novo Nordisk A/S | Freeze-dried preparation of human growth hormone |
| JP2004515467A (ja) | 2000-08-07 | 2004-05-27 | ネクター セラピューティックス | 吸入可能な、噴霧乾燥した、最少の凝集物を有する４−ヘリックスバンドルタンパク質粉末 |
| WO2002028375A1 (en) | 2000-10-06 | 2002-04-11 | Jagotec Ag | A controlled-release, parenterally administrable microparticle preparation |
| SE517422C2 (sv) | 2000-10-06 | 2002-06-04 | Bioglan Ab | Farmaceutiskt acceptabel stärkelse |
| SE517421C2 (sv) | 2000-10-06 | 2002-06-04 | Bioglan Ab | Mikropartiklar, lämpade för parenteral administration, väsentligen bestående av stärkelse med minst 85 % amylopektin och med reducerad molekylvikt, samt framställning därav |
| SE518007C2 (sv) | 2000-11-16 | 2002-08-13 | Bioglan Ab | Förfarande för framställning av mikropartiklar |
| US7105181B2 (en) | 2001-10-05 | 2006-09-12 | Jagotec, Ag | Microparticles |
| SE0201599D0 (sv) | 2002-03-21 | 2002-05-30 | Skyepharma Ab | Microparticles |
| SE0202719D0 (sv) * | 2002-09-13 | 2002-09-13 | Pharmacia Ab | Process for mfg crystals of growth hormone |
| BR0317888A (pt) * | 2002-12-31 | 2005-12-06 | Altus Pharmaceuticals Inc | Cristais do hormÈnio do crescimento humano e processos para preparação dos mesmos |
| ZA200505305B (en) * | 2002-12-31 | 2007-07-25 | Altus Pharmaceuticals Inc | Human growth hormone crystals and methods for preparing them |
| NZ571243A (en) * | 2002-12-31 | 2010-04-30 | Altus Pharmaceuticals Inc | Complexes of protein crystals and ionic polymers comprising human growth hormone and protamine |
| US20050032698A1 (en) * | 2003-07-14 | 2005-02-10 | Nps Allelix Corp. | Stabilized formulation of parathyroid hormone |
| JP2009521486A (ja) * | 2005-12-23 | 2009-06-04 | アルタス ファーマシューティカルズ インコーポレイテッド | ポリカチオン錯化タンパク質結晶を含む組成物およびこれを使用した治療法 |
| JP2010513309A (ja) * | 2006-12-18 | 2010-04-30 | アルタス ファーマシューティカルズ インコーポレイテッド | ヒト成長ホルモン製剤 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA653324A (en) * | 1962-12-04 | G. Brink Norman | Growth hormone and methods of preparing the same | |
| US2143590A (en) * | 1936-09-26 | 1939-01-10 | Univ Alberta | Insulin preparation and process of producing crystals of insulin |
| US2174862A (en) * | 1938-12-30 | 1939-10-03 | Frederick Stearns & Company | Process of producing crystalline insulin |
| US2595278A (en) * | 1950-04-28 | 1952-05-06 | Armour & Co | Preparation of insulin from pancreas glands |
| US3102077A (en) * | 1953-08-19 | 1963-08-27 | Christensen Henry Marinus | Preparation of insulin containing 2.75 to 8 percent zinc content |
| US2897117A (en) * | 1955-02-10 | 1959-07-28 | Univ Alberta | Insulin process |
| US3856771A (en) * | 1973-07-16 | 1974-12-24 | Lilly Co Eli | Process for manufacturing alkali metal or ammonium insulin |
| ATE62598T1 (de) * | 1984-10-04 | 1991-05-15 | Monsanto Co | Verzoegerte freisetzung biologisch aktiver somatotropine. |
| KR890002631B1 (ko) * | 1984-10-04 | 1989-07-21 | 몬산토 캄파니 | 생물학적으로 활성인 소마토트로핀을 지속적으로 유리하는 조성물 |
| IL79681A (en) * | 1985-08-12 | 1991-06-10 | Int Minerals & Chem Corp | Transition metal complexes of growth hormones and their prolonged release compositions |
| EP0277043A3 (en) * | 1987-01-30 | 1989-08-23 | IMCERA Group Inc. | Method for recovering somatotropins from dilute aqueous solution |
| US4764592A (en) * | 1987-04-23 | 1988-08-16 | Eli Lilly And Company | Crystalline human proinsulin and process for its production |
| DE68929273T2 (de) * | 1988-08-24 | 2001-07-05 | American Cyanamid Co | Stabilisierung von Somatotropinen durch Modifikation von Cystein-Resten durch orts-spezifische Mutagenese oder chemische Derivatisierung |
| US5109117A (en) * | 1990-06-26 | 1992-04-28 | Monsanto Company | Method of somatotropin naturation using urea and a soluble organic alcohol |
| DK168790D0 (ru) * | 1990-07-13 | 1990-07-13 | Novo Nordisk As | |
| US5780599A (en) * | 1990-07-13 | 1998-07-14 | Novo Nordisk A/S | Growth hormone crystals and a process for production of growth hormone crystals |
-
1990
- 1990-07-13 DK DK168790A patent/DK168790D0/da active IP Right Grant
-
1991
- 1991-07-10 NZ NZ238904A patent/NZ238904A/xx unknown
- 1991-07-11 PT PT98297A patent/PT98297B/pt not_active IP Right Cessation
- 1991-07-12 CA CA002086087A patent/CA2086087C/en not_active Expired - Fee Related
- 1991-07-12 RU RU93005051/13A patent/RU2108341C1/ru not_active IP Right Cessation
- 1991-07-12 ZA ZA915446A patent/ZA915446B/xx unknown
- 1991-07-12 DK DK91913240.7T patent/DK0540582T3/da active
- 1991-07-12 IE IE244491A patent/IE67054B1/en not_active IP Right Cessation
- 1991-07-12 EP EP91913240A patent/EP0540582B1/en not_active Expired - Lifetime
- 1991-07-12 HU HU9300067A patent/HUT64086A/hu unknown
- 1991-07-12 AT AT91913240T patent/ATE110745T1/de not_active IP Right Cessation
- 1991-07-12 JP JP3512511A patent/JP2524446B2/ja not_active Expired - Fee Related
- 1991-07-12 AU AU82846/91A patent/AU666465B2/en not_active Ceased
- 1991-07-12 HU HU9300067A patent/HU210323B/hu unknown
- 1991-07-12 WO PCT/DK1991/000203 patent/WO1992000998A1/en active IP Right Grant
- 1991-07-12 DE DE69103755T patent/DE69103755T2/de not_active Expired - Fee Related
- 1991-07-12 ES ES91913240T patent/ES2060399T3/es not_active Expired - Lifetime
-
1993
- 1993-01-12 BG BG97281A patent/BG61267B1/bg unknown
-
1998
- 1998-04-21 US US09/063,749 patent/US6117984A/en not_active Expired - Fee Related
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