RU92016545A - Гетероциклические соединения, способ их получения и фармацевтическая композиция - Google Patents

Гетероциклические соединения, способ их получения и фармацевтическая композиция

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Publication number
RU92016545A
RU92016545A RU92016545/04A RU92016545A RU92016545A RU 92016545 A RU92016545 A RU 92016545A RU 92016545/04 A RU92016545/04 A RU 92016545/04A RU 92016545 A RU92016545 A RU 92016545A RU 92016545 A RU92016545 A RU 92016545A
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RU
Russia
Prior art keywords
optionally substituted
production
pharmaceutical composition
heterocyclic compounds
alkyl
Prior art date
Application number
RU92016545/04A
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English (en)
Other versions
RU2099323C1 (ru
Inventor
Гопалан Баласабраманьян
Original Assignee
Дзе Бутс Компани ПЛС
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Priority claimed from IN126BO1990 external-priority patent/IN172842B/en
Priority claimed from GB909014456A external-priority patent/GB9014456D0/en
Application filed by Дзе Бутс Компани ПЛС filed Critical Дзе Бутс Компани ПЛС
Publication of RU92016545A publication Critical patent/RU92016545A/ru
Application granted granted Critical
Publication of RU2099323C1 publication Critical patent/RU2099323C1/ru

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Claims (1)

  1. Предлагаются соединения формулы
    Figure 00000001

    и их фармацевтически приемлемые соли, где R1 является необязательно замещенным фенилом, R2 является необязательно замещенным амином, либо R2 и R3 вместе с атомами азота и углерода, к которым они присоединены, образуют необязательно замещенное гетероциклическое кольцо, либо R3 и R4 вместе с атомом азота, к которому они присоединены, образуют необязательно замещенное гетероциклическое кольцо, и R5-водородом, галоидом, алкил, алкокси, трифторметил или группой формулы S(O)mR8, где m = 0, 1 или 2, и R8 является алкилом. Данные соединения применимы для лечения диабетов, особенно для лечения гипергликемии.
RU9292016545A 1990-05-17 1991-05-15 Производные гуанидина, способ их получения и фармацевтическая композиция, обладающая гипогликемической активностью RU2099323C1 (ru)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
IN126BO1990 IN172842B (ru) 1990-05-17 1990-05-17
GB9014456.9 1990-06-28
GB909014456A GB9014456D0 (en) 1990-06-28 1990-06-28 Therapeutic agents
PCT/EP1991/000911 WO1992000273A1 (en) 1990-05-17 1991-05-15 Orthosubstituted biphenyl amidine and biphenyl guanidine derivatives and antidiabetic or hypoglycaemic agents containing them

Publications (2)

Publication Number Publication Date
RU92016545A true RU92016545A (ru) 1995-05-20
RU2099323C1 RU2099323C1 (ru) 1997-12-20

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RU9292016545A RU2099323C1 (ru) 1990-05-17 1991-05-15 Производные гуанидина, способ их получения и фармацевтическая композиция, обладающая гипогликемической активностью

Country Status (27)

Country Link
US (1) US5302720A (ru)
EP (1) EP0536151B1 (ru)
JP (1) JPH089589B2 (ru)
KR (1) KR920005714A (ru)
CN (1) CN1028521C (ru)
AT (1) ATE111445T1 (ru)
AU (1) AU637695B2 (ru)
BG (1) BG61260B1 (ru)
CA (1) CA2041846A1 (ru)
CZ (1) CZ280182B6 (ru)
DE (1) DE69104041T4 (ru)
DK (1) DK0536151T3 (ru)
ES (1) ES2064103T3 (ru)
FI (1) FI95566C (ru)
GB (1) GB2244486B (ru)
HR (1) HRP930699A2 (ru)
HU (1) HU210200B (ru)
IE (1) IE64485B1 (ru)
IL (1) IL98029A (ru)
IN (1) IN172842B (ru)
MX (1) MX25770A (ru)
NO (1) NO179204C (ru)
NZ (1) NZ238119A (ru)
PL (1) PL167657B1 (ru)
PT (1) PT97700B (ru)
RU (1) RU2099323C1 (ru)
WO (1) WO1992000273A1 (ru)

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