RU2749717C2 - Способ временной трансфекции для продуцирования ретровируса - Google Patents

Способ временной трансфекции для продуцирования ретровируса Download PDF

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RU2749717C2
RU2749717C2 RU2018118964A RU2018118964A RU2749717C2 RU 2749717 C2 RU2749717 C2 RU 2749717C2 RU 2018118964 A RU2018118964 A RU 2018118964A RU 2018118964 A RU2018118964 A RU 2018118964A RU 2749717 C2 RU2749717 C2 RU 2749717C2
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nucleic acid
vector
retroviral
acid vector
replication
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RU2018118964A
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Russian (ru)
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RU2018118964A (ru
RU2018118964A3 (enExample
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Сабин ДЖОНСОН
Селест ПАЛЛАНТ
Эйрини ВАМВА
Конрад ВИНК
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Глэксосмитклайн Интеллекчуал Проперти Дивелопмент Лимитед
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Priority claimed from GBGB1609354.4A external-priority patent/GB201609354D0/en
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
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    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/89—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microinjection
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    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
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    • C12N2740/16041—Use of virus, viral particle or viral elements as a vector
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    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16051—Methods of production or purification of viral material
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    • C12N2800/00—Nucleic acids vectors
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    • C12N2800/204—Pseudochromosomes, minichrosomosomes of bacterial origin, e.g. BAC
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    • C12N2800/22—Vectors comprising a coding region that has been codon optimised for expression in a respective host
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    • C12N2800/00—Nucleic acids vectors
    • C12N2800/50—Vectors for producing vectors

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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RU2018118964A 2015-11-24 2016-11-21 Способ временной трансфекции для продуцирования ретровируса RU2749717C2 (ru)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB1520764.0 2015-11-24
GBGB1520764.0A GB201520764D0 (en) 2015-11-24 2015-11-24 Transient transfection method for retroviral production
GB1609354.4 2016-05-26
GBGB1609354.4A GB201609354D0 (en) 2016-05-26 2016-05-26 Transient transfection method for retroviral production
PCT/EP2016/078334 WO2017089307A1 (en) 2015-11-24 2016-11-21 Transient transfection method for retroviral production

Publications (3)

Publication Number Publication Date
RU2018118964A RU2018118964A (ru) 2019-12-26
RU2018118964A3 RU2018118964A3 (enExample) 2020-04-02
RU2749717C2 true RU2749717C2 (ru) 2021-06-16

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US (2) US10450574B2 (enExample)
EP (1) EP3380605A1 (enExample)
JP (1) JP7110096B2 (enExample)
KR (1) KR102067352B1 (enExample)
CN (1) CN108291211A (enExample)
AU (1) AU2016359838B2 (enExample)
BR (1) BR112018010639A2 (enExample)
CA (1) CA3006285A1 (enExample)
DE (1) DE102016122317A1 (enExample)
FR (1) FR3044017B1 (enExample)
IL (1) IL259223B (enExample)
IT (1) IT201600117287A1 (enExample)
RU (1) RU2749717C2 (enExample)
SA (1) SA518391585B1 (enExample)
WO (1) WO2017089307A1 (enExample)

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WO2016185125A1 (fr) * 2015-05-15 2016-11-24 Vectalys Particule rétrovirale comportant au moins deux arn non viraux encapsidés
FR3044016A1 (fr) * 2015-11-24 2017-05-26 Glaxosmithkline Ip Dev Ltd Lignees cellulaires stables pour la production retrovirale
GB201706121D0 (en) 2017-04-18 2017-05-31 Glaxosmithkline Ip Dev Ltd Stable cell lines for retroviral production
GB201715052D0 (en) 2017-09-19 2017-11-01 Oxford Genetics Ltd Vectors
FI3633040T3 (fi) * 2017-12-22 2023-08-03 Oxford Biomedica Ltd Retrovirusvektori
GB201816919D0 (en) * 2018-10-17 2018-11-28 Glaxosmithkline Ip Dev Ltd Adeno-associated viral vector producer cell lines
CN110684804B (zh) * 2019-10-15 2023-04-18 上海本导基因技术有限公司 递送外源rnp的慢病毒载体及其制备方法
GB202004371D0 (en) 2020-03-26 2020-05-13 Glaxosmithkline Ip Dev Ltd CAR constructs
GB202005096D0 (en) 2020-04-07 2020-05-20 Glaxosmithkline Modified vectors for production of retrovirus
CN117377691A (zh) 2021-03-19 2024-01-09 葛兰素史密斯克莱知识产权发展有限公司 靶向密蛋白3的嵌合抗原受体和治疗癌症的方法
CN113373266B (zh) * 2021-06-22 2022-07-01 内蒙古农业大学 一种用于检测绵羊肺腺瘤病毒的荧光rpa引物、试剂盒和检测方法
EP4422787A1 (en) 2021-10-28 2024-09-04 Southwest Research Institute Devices for cell separation
EP4698215A1 (en) 2023-04-19 2026-02-25 GlaxoSmithKline Intellectual Property Development Limited Cytotoxicity targeting chimeras for car-t and car-nk cells
WO2024218345A1 (en) 2023-04-21 2024-10-24 Glaxosmithkline Intellectual Property Development Limited Cytotoxicity targeting chimeras for antibody-drug conjugates and bispecific antibodies
WO2026032970A1 (en) 2024-08-07 2026-02-12 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Cd4-specific chimeric antigen receptor and methods and uses thereof

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RU2174845C2 (ru) * 1993-01-26 2001-10-20 Америкэн Хоум Продактс Корпорэйшн Композиции и способы доставки генетического материала
RU2187301C2 (ru) * 1995-06-27 2002-08-20 Бавариан Нордик А/С Капсула для клеток, продуцирующих вирусные частицы, способ ее получения и использования
RU2312676C2 (ru) * 1996-07-19 2007-12-20 Мериаль Формула кошачьей вакцины
RU2290441C2 (ru) * 2000-10-31 2006-12-27 Ридженерон Фармасьютикалз, Инк. Способ генетической модификации интересующего эндогенного гена или хромосомного локуса (варианты) и его использование
EA012723B1 (ru) * 2002-11-25 2009-12-30 Бавариан Нордик А/С Рекомбинантный поксвирус, содержащий по меньшей мере два промотора ati вируса коровьей оспы, и его применение
RU2416646C2 (ru) * 2004-04-28 2011-04-20 Дзе Трастиз Оф Дзе Юниверсити Оф Пенсильвания Поливалентные вирусные векторы и система для их получения
EP1829963A1 (en) * 2004-11-24 2007-09-05 Anaeropharma Science Inc. Novel shuttle vector
WO2012028681A1 (en) * 2010-09-02 2012-03-08 Molmed Spa Stable production of lentiviral vectors

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FR3044017A1 (fr) 2017-05-26
AU2016359838B2 (en) 2020-08-06
IL259223A (en) 2018-07-31
WO2017089307A1 (en) 2017-06-01
RU2018118964A (ru) 2019-12-26
RU2018118964A3 (enExample) 2020-04-02
FR3044017B1 (fr) 2019-05-03
KR102067352B1 (ko) 2020-01-16
IL259223B (en) 2022-05-01
BR112018010639A2 (pt) 2019-01-22
KR20180073624A (ko) 2018-07-02
JP7110096B2 (ja) 2022-08-01
AU2016359838A1 (en) 2018-05-24
EP3380605A1 (en) 2018-10-03
JP2019500030A (ja) 2019-01-10
DE102016122317A1 (de) 2017-05-24
IT201600117287A1 (it) 2018-05-21
US20200063144A1 (en) 2020-02-27
CA3006285A1 (en) 2017-06-01
CN108291211A (zh) 2018-07-17
SA518391585B1 (ar) 2020-10-26
US20170145427A1 (en) 2017-05-25
US10450574B2 (en) 2019-10-22

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