RU2742828C2 - Применение стволовых клеток, экспрессирующих мезенхимальные и нейрональные маркеры, и их композиций для лечения неврологических заболеваний (варианты) - Google Patents
Применение стволовых клеток, экспрессирующих мезенхимальные и нейрональные маркеры, и их композиций для лечения неврологических заболеваний (варианты) Download PDFInfo
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- RU2742828C2 RU2742828C2 RU2018134615A RU2018134615A RU2742828C2 RU 2742828 C2 RU2742828 C2 RU 2742828C2 RU 2018134615 A RU2018134615 A RU 2018134615A RU 2018134615 A RU2018134615 A RU 2018134615A RU 2742828 C2 RU2742828 C2 RU 2742828C2
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- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
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- A61P37/00—Drugs for immunological or allergic disorders
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
- C12N5/0664—Dental pulp stem cells, Dental follicle stem cells
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- Bioinformatics & Cheminformatics (AREA)
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- Pharmacology & Pharmacy (AREA)
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- General Chemical & Material Sciences (AREA)
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- Zoology (AREA)
- Biotechnology (AREA)
- Neurology (AREA)
- Immunology (AREA)
- Developmental Biology & Embryology (AREA)
- Neurosurgery (AREA)
- Cell Biology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
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- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15/065,259 | 2016-03-09 | ||
| US15/065,259 US11207352B2 (en) | 2013-03-15 | 2016-03-09 | Compositions comprising stem cells expressing mesenchymal and neuronal markers and uses thereof to treat neurological disease |
| PCT/IB2017/051404 WO2017153956A1 (en) | 2016-03-09 | 2017-03-09 | Uses of dental pulp stem cells expressing mesenchymal and neuronal markers and compositions thereof to treat neurological disease |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| RU2018134615A RU2018134615A (ru) | 2020-04-10 |
| RU2018134615A3 RU2018134615A3 (https=) | 2020-07-28 |
| RU2742828C2 true RU2742828C2 (ru) | 2021-02-11 |
Family
ID=58387859
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2018134615A RU2742828C2 (ru) | 2016-03-09 | 2017-03-09 | Применение стволовых клеток, экспрессирующих мезенхимальные и нейрональные маркеры, и их композиций для лечения неврологических заболеваний (варианты) |
| RU2018134710A RU2741839C2 (ru) | 2016-03-09 | 2017-03-09 | Стволовые клетки, экспрессирующие мезенхимальные и нейрональные маркеры, их композиции и способы их получения |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2018134710A RU2741839C2 (ru) | 2016-03-09 | 2017-03-09 | Стволовые клетки, экспрессирующие мезенхимальные и нейрональные маркеры, их композиции и способы их получения |
Country Status (8)
| Country | Link |
|---|---|
| EP (2) | EP3426770A1 (https=) |
| JP (2) | JP6997716B2 (https=) |
| KR (2) | KR102497999B1 (https=) |
| CN (2) | CN109219441B (https=) |
| CA (1) | CA3055398A1 (https=) |
| IL (2) | IL261622B2 (https=) |
| RU (2) | RU2742828C2 (https=) |
| WO (2) | WO2017153956A1 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109152801A (zh) * | 2016-05-16 | 2019-01-04 | 国立大学法人名古屋大学 | 采用多能干细胞的围产期脑损伤的改善及治疗 |
| US11547730B2 (en) | 2017-05-26 | 2023-01-10 | Steminent Biotherapeutics Inc. | Therapy for polyglutamine (polyQ) diseases |
| KR20210041578A (ko) * | 2018-07-31 | 2021-04-15 | 제이씨알 파마 가부시키가이샤 | 치수 유래 세포의 제조 방법 |
| DK3894857T3 (da) * | 2019-04-15 | 2022-11-07 | Nanologica Ab | Tomme porøse partikler til anvendelse ved behandling, forebyggelse og/eller udskydelse af degeneration af neurodegenerative sygdomme, neuroner og glia |
| CN110179827A (zh) * | 2019-06-27 | 2019-08-30 | 北京三有利和泽生物科技有限公司 | 牙源性间充质干细胞的应用 |
| CN110314172A (zh) * | 2019-07-17 | 2019-10-11 | 中国医科大学附属第一医院 | 一种用于治疗脊髓损伤的细胞制剂及其制备方法 |
| JPWO2021200744A1 (https=) * | 2020-03-31 | 2021-10-07 | ||
| CN111973631A (zh) * | 2020-08-21 | 2020-11-24 | 卡替(上海)生物技术有限公司 | 牙髓间充质干细胞在制备阿尔茨海默病治疗药物中的用途 |
| CN115192609A (zh) * | 2022-05-10 | 2022-10-18 | 湖南中南大学湘雅口腔医院 | 间充质干细胞在制备治疗抑郁症的药物中的应用 |
| WO2025084896A1 (ko) * | 2023-10-18 | 2025-04-24 | 연세대학교 산학협력단 | 신경세포 분화 유도용 재조합 벡터 및 이를 포함하는 퇴행성 뇌신경 질환의 예방 또는 치료용 약학적 조성물 |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2347579C1 (ru) * | 2007-07-03 | 2009-02-27 | Общество с ограниченной ответственностью "Медицинские технологии" | Способ получения клеточной культуры для лечения сосудистых и демиелинизирующих заболеваний нервной системы и клеточная культура, полученная этим способом (варианты) |
| US20110158962A1 (en) * | 2008-06-26 | 2011-06-30 | Federico Ferro | Dental pulp marrow similar cells (dpmsc) and methods of isolating and using |
| US20150050248A1 (en) * | 2013-03-15 | 2015-02-19 | Avita International Ltd. | Multifunctional immature dental pulp stem cells and therapeutic applications |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2465924A3 (en) | 2005-06-16 | 2013-01-02 | Ramot at Tel-Aviv University Ltd. | Isolated cells and populations comprising same for the treament of cns diseases |
| WO2008080200A1 (en) * | 2006-12-29 | 2008-07-10 | Irina Kerkis | Process for obtaining stem cells |
| CN101668848B (zh) | 2007-04-26 | 2014-10-22 | 雷蒙特亚特特拉维夫大学有限公司 | 来自口腔粘膜的多能自体干细胞和使用方法 |
| JP5408578B2 (ja) * | 2007-12-05 | 2014-02-05 | 国立大学法人名古屋大学 | 歯髄幹細胞を用いた自家又は同種移植用組成物及びその用途 |
| EP2263706B1 (en) * | 2008-03-12 | 2017-11-15 | National Center for Geriatrics and Gerontology | Root canal filler and dental tissue regeneration method |
| EP2620493B1 (en) | 2008-05-28 | 2019-03-27 | Ramot at Tel Aviv University Ltd. | Mesenchymal stem cells for the treatment of CNS diseases |
| CN102725398B (zh) * | 2009-12-21 | 2014-01-08 | 学校法人总持学园鹤见大学 | 用于培养及保存牙髓细胞的离体牙的移送方法 |
| WO2012117373A1 (en) | 2011-03-03 | 2012-09-07 | Ramot At Tel-Aviv University Ltd. | Genetically modified muscle cells which express neurotrophic factors |
| WO2013076726A1 (en) | 2011-11-21 | 2013-05-30 | Ramot At Tel-Aviv University Ltd. | Stem cell-derived neural cells for cell therapy in neurological disorders |
| EP2633870B1 (en) * | 2012-02-29 | 2018-08-01 | Technische Universität Berlin | Method of preparing an artificial tooth primordium in vitro and artificial tooth primordium derived therefrom |
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2017
- 2017-03-09 RU RU2018134615A patent/RU2742828C2/ru active
- 2017-03-09 RU RU2018134710A patent/RU2741839C2/ru active
- 2017-03-09 IL IL261622A patent/IL261622B2/en unknown
- 2017-03-09 EP EP17714293.2A patent/EP3426770A1/en active Pending
- 2017-03-09 CN CN201780027504.4A patent/CN109219441B/zh active Active
- 2017-03-09 IL IL261623A patent/IL261623B2/en unknown
- 2017-03-09 JP JP2018546842A patent/JP6997716B2/ja active Active
- 2017-03-09 CA CA3055398A patent/CA3055398A1/en active Pending
- 2017-03-09 WO PCT/IB2017/051404 patent/WO2017153956A1/en not_active Ceased
- 2017-03-09 CN CN201780028519.2A patent/CN109312303B/zh active Active
- 2017-03-09 KR KR1020187028974A patent/KR102497999B1/ko active Active
- 2017-03-09 WO PCT/IB2017/051405 patent/WO2017153957A1/en not_active Ceased
- 2017-03-09 KR KR1020187028975A patent/KR102363146B1/ko active Active
- 2017-03-09 EP EP17712549.9A patent/EP3426267B1/en active Active
- 2017-03-09 JP JP2018546882A patent/JP7008031B2/ja active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2347579C1 (ru) * | 2007-07-03 | 2009-02-27 | Общество с ограниченной ответственностью "Медицинские технологии" | Способ получения клеточной культуры для лечения сосудистых и демиелинизирующих заболеваний нервной системы и клеточная культура, полученная этим способом (варианты) |
| US20110158962A1 (en) * | 2008-06-26 | 2011-06-30 | Federico Ferro | Dental pulp marrow similar cells (dpmsc) and methods of isolating and using |
| US20150050248A1 (en) * | 2013-03-15 | 2015-02-19 | Avita International Ltd. | Multifunctional immature dental pulp stem cells and therapeutic applications |
Non-Patent Citations (1)
| Title |
|---|
| SAKAI K., et al. "Human dental pulp-derived stem cells promote locomotor recovery after complete transection of the rat spinal cord by multiple neuro-regenerative mechanisms", JCI. 2012; 122(1):80-90; DOI: 10.1172/JCI59251. * |
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