CN109219441B - 表达间充质和神经元标志物的牙髓干细胞及其组合物治疗神经疾病的用途 - Google Patents

表达间充质和神经元标志物的牙髓干细胞及其组合物治疗神经疾病的用途 Download PDF

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CN109219441B
CN109219441B CN201780027504.4A CN201780027504A CN109219441B CN 109219441 B CN109219441 B CN 109219441B CN 201780027504 A CN201780027504 A CN 201780027504A CN 109219441 B CN109219441 B CN 109219441B
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cells
hidpscs
disease
stem cells
expression
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CN109219441A (zh
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I·柯奇斯
文塞斯劳 C·瓦尔韦德
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Fundacao Butantan
Avita International Ltd
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Avita International Ltd
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CN201780027504.4A 2016-03-09 2017-03-09 表达间充质和神经元标志物的牙髓干细胞及其组合物治疗神经疾病的用途 Active CN109219441B (zh)

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Application Number Priority Date Filing Date Title
US15/065,259 2016-03-09
US15/065,259 US11207352B2 (en) 2013-03-15 2016-03-09 Compositions comprising stem cells expressing mesenchymal and neuronal markers and uses thereof to treat neurological disease
PCT/IB2017/051404 WO2017153956A1 (en) 2016-03-09 2017-03-09 Uses of dental pulp stem cells expressing mesenchymal and neuronal markers and compositions thereof to treat neurological disease

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CN109219441A CN109219441A (zh) 2019-01-15
CN109219441B true CN109219441B (zh) 2022-06-10

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CN201780028519.2A Active CN109312303B (zh) 2016-03-09 2017-03-09 表达间充质和神经元标志物的干细胞、其组合物及其制备方法

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EP (2) EP3426770A1 (https=)
JP (2) JP6997716B2 (https=)
KR (2) KR102497999B1 (https=)
CN (2) CN109219441B (https=)
CA (1) CA3055398A1 (https=)
IL (2) IL261622B2 (https=)
RU (2) RU2742828C2 (https=)
WO (2) WO2017153956A1 (https=)

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CN109152801A (zh) * 2016-05-16 2019-01-04 国立大学法人名古屋大学 采用多能干细胞的围产期脑损伤的改善及治疗
US11547730B2 (en) 2017-05-26 2023-01-10 Steminent Biotherapeutics Inc. Therapy for polyglutamine (polyQ) diseases
KR20210041578A (ko) * 2018-07-31 2021-04-15 제이씨알 파마 가부시키가이샤 치수 유래 세포의 제조 방법
DK3894857T3 (da) * 2019-04-15 2022-11-07 Nanologica Ab Tomme porøse partikler til anvendelse ved behandling, forebyggelse og/eller udskydelse af degeneration af neurodegenerative sygdomme, neuroner og glia
CN110179827A (zh) * 2019-06-27 2019-08-30 北京三有利和泽生物科技有限公司 牙源性间充质干细胞的应用
CN110314172A (zh) * 2019-07-17 2019-10-11 中国医科大学附属第一医院 一种用于治疗脊髓损伤的细胞制剂及其制备方法
JPWO2021200744A1 (https=) * 2020-03-31 2021-10-07
CN111973631A (zh) * 2020-08-21 2020-11-24 卡替(上海)生物技术有限公司 牙髓间充质干细胞在制备阿尔茨海默病治疗药物中的用途
CN115192609A (zh) * 2022-05-10 2022-10-18 湖南中南大学湘雅口腔医院 间充质干细胞在制备治疗抑郁症的药物中的应用
WO2025084896A1 (ko) * 2023-10-18 2025-04-24 연세대학교 산학협력단 신경세포 분화 유도용 재조합 벡터 및 이를 포함하는 퇴행성 뇌신경 질환의 예방 또는 치료용 약학적 조성물

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WO2008080200A1 (en) * 2006-12-29 2008-07-10 Irina Kerkis Process for obtaining stem cells
CN101668848B (zh) 2007-04-26 2014-10-22 雷蒙特亚特特拉维夫大学有限公司 来自口腔粘膜的多能自体干细胞和使用方法
RU2347579C1 (ru) * 2007-07-03 2009-02-27 Общество с ограниченной ответственностью "Медицинские технологии" Способ получения клеточной культуры для лечения сосудистых и демиелинизирующих заболеваний нервной системы и клеточная культура, полученная этим способом (варианты)
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CA3055398A1 (en) 2017-09-14
CN109219441A (zh) 2019-01-15
CA3055399A1 (en) 2017-09-14
RU2018134615A3 (https=) 2020-07-28
RU2018134710A (ru) 2020-04-09
JP2019507772A (ja) 2019-03-22
JP2019510758A (ja) 2019-04-18
IL261623A (en) 2018-10-31
EP3426770A1 (en) 2019-01-16
WO2017153957A9 (en) 2017-11-02
RU2018134710A3 (https=) 2020-06-25
JP6997716B2 (ja) 2022-02-04
BR112018067969A2 (pt) 2019-01-15
CN109312303B (zh) 2024-03-26
WO2017153957A1 (en) 2017-09-14
EP3426267B1 (en) 2023-01-11
RU2741839C2 (ru) 2021-01-29
RU2742828C2 (ru) 2021-02-11
RU2018134615A (ru) 2020-04-10
BR112018067971A2 (pt) 2019-01-15
CN109312303A (zh) 2019-02-05
IL261622B2 (en) 2023-09-01
KR102497999B1 (ko) 2023-02-08
WO2017153956A1 (en) 2017-09-14
IL261623B1 (en) 2023-11-01
EP3426267A1 (en) 2019-01-16
IL261622A (en) 2018-10-31
IL261622B1 (en) 2023-05-01
IL261623B2 (en) 2024-03-01
KR20180137488A (ko) 2018-12-27
KR102363146B1 (ko) 2022-02-14
KR20190003489A (ko) 2019-01-09
JP7008031B2 (ja) 2022-02-10

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