RU2734760C2 - Противоинфекционные соединения - Google Patents
Противоинфекционные соединения Download PDFInfo
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- RU2734760C2 RU2734760C2 RU2016107378A RU2016107378A RU2734760C2 RU 2734760 C2 RU2734760 C2 RU 2734760C2 RU 2016107378 A RU2016107378 A RU 2016107378A RU 2016107378 A RU2016107378 A RU 2016107378A RU 2734760 C2 RU2734760 C2 RU 2734760C2
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
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- Epidemiology (AREA)
- Pulmonology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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| PCT/EP2014/066614 WO2015014993A2 (en) | 2013-08-02 | 2014-08-01 | Anti-infective compounds |
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| KR20180053386A (ko) * | 2015-09-17 | 2018-05-21 | 마빈 제이. 밀러 | 마이코박테리아 감염에 대해 유용한 벤질 아민-함유 헤테로사이클릭 화합물 및 조성물 |
| JP2019518046A (ja) * | 2016-06-16 | 2019-06-27 | ヤンセン・サイエンシズ・アイルランド・アンリミテッド・カンパニー | 抗菌薬としての複素環式化合物 |
| US20200308169A1 (en) | 2016-06-16 | 2020-10-01 | Janssen Sciences Ireland Unlimited Company | Heterocyclic compounds as antibacterials |
| KR20190121315A (ko) | 2017-03-01 | 2019-10-25 | 얀센 사이언시즈 아일랜드 언리미티드 컴퍼니 | 병용 요법 |
| CN111246848A (zh) * | 2017-10-05 | 2020-06-05 | 快尔生物技术公司 | 与抗结核药物组合的环稠和的噻唑并2-吡啶酮 |
| CN108101828B (zh) * | 2018-01-15 | 2021-05-04 | 西华师范大学 | 3-吲哚基甲酰胺类化合物及其制备方法 |
| CN108159049B (zh) * | 2018-02-01 | 2021-01-05 | 中国科学院广州生物医药与健康研究院 | 一种吡啶类化合物的新用途 |
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| CN114450288A (zh) * | 2019-09-30 | 2022-05-06 | 爱尔兰詹森科学公司 | 4-喹啉酮抗细菌化合物 |
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| EP4423097A1 (en) | 2021-10-28 | 2024-09-04 | Janssen Sciences Ireland Unlimited Company | Imidazopyridine amides and related compounds for use in the treatment of bacterial infections |
| JP2025530847A (ja) * | 2022-09-16 | 2025-09-17 | 北京華益健康薬物研究中心 | Ｍｅｔｔｌ３阻害剤化合物、その医薬組成物及び用途 |
| WO2024089170A1 (en) | 2022-10-27 | 2024-05-02 | Janssen Sciences Ireland Unlimited Company | Antibacterial compounds |
| WO2024223859A1 (en) | 2023-04-26 | 2024-10-31 | Janssen Pharmaceutica Nv | Antibacterial compounds |
| KR20260041840A (ko) | 2023-07-18 | 2026-03-27 | 얀센 파마슈티카 엔브이 | 베다퀼린, 프레토마니드 또는 델라마니드, 및 시토크롬 bc1 억제제를 포함하는 적어도 세 가지 항생제의 조합 제품 및 미코박테리아 감염 치료에서의 이들의 용도 |
| CN117946118A (zh) * | 2024-01-15 | 2024-04-30 | 珃诺生物医药科技(杭州)有限公司 | 一种靶向降解erk5蛋白的化合物及其制备方法 |
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| WO2011057145A2 (en) * | 2009-11-05 | 2011-05-12 | University Of Notre Dame Du Lac | Imidazo[1,2-a] pyridine compounds, synthesis thereof, and methods of using same |
| WO2011113606A1 (en) * | 2010-03-18 | 2011-09-22 | Institut Pasteur Korea | Anti-infective compounds |
| WO2012143796A2 (en) * | 2011-04-21 | 2012-10-26 | Institut Pasteur Korea | Anti-inflammation compounds |
| EA017442B1 (ru) * | 2006-09-22 | 2012-12-28 | Санофи-Авентис | ПРОИЗВОДНЫЕ 2-АРИЛ-6-ФЕНИЛИМИДАЗО[1,2-a]ПИРИДИНОВ, ИХ ПОЛУЧЕНИЕ И ПРИМЕНЕНИЕ В ТЕРАПИИ |
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| US20100298314A1 (en) * | 2006-12-20 | 2010-11-25 | Schering Corporation | Novel jnk inhibitors |
| WO2009140101A2 (en) * | 2008-05-12 | 2009-11-19 | Boehringer Ingelheim International Gmbh | Imidazopyridine compounds useful as mmp-13 inhibitors |
| CN103324035B (zh) * | 2013-06-20 | 2015-07-01 | 深圳市华星光电技术有限公司 | 掩膜板和阵列基板的制作方法 |
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2014
- 2014-08-01 JP JP2016530547A patent/JP2016525562A/ja not_active Withdrawn
- 2014-08-01 US US14/909,663 patent/US20160185774A1/en not_active Abandoned
- 2014-08-01 WO PCT/EP2014/066614 patent/WO2015014993A2/en not_active Ceased
- 2014-08-01 CN CN201811384685.9A patent/CN109575018A/zh active Pending
- 2014-08-01 CN CN201480054331.1A patent/CN105745208A/zh active Pending
- 2014-08-01 RU RU2016107378A patent/RU2734760C2/ru active
- 2014-08-01 SG SG11201600686QA patent/SG11201600686QA/en unknown
- 2014-08-01 ES ES14745158T patent/ES2883565T3/es active Active
- 2014-08-01 HU HUE14745158A patent/HUE056198T2/hu unknown
- 2014-08-01 KR KR1020167005457A patent/KR102292293B1/ko active Active
- 2014-08-01 DK DK14745158.7T patent/DK3027615T3/da active
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2016
- 2016-01-29 PH PH12016500207A patent/PH12016500207A1/en unknown
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2018
- 2018-06-25 JP JP2018119810A patent/JP6757768B2/ja active Active
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- 2019-04-15 JP JP2019077088A patent/JP2019131606A/ja active Pending
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EA017442B1 (ru) * | 2006-09-22 | 2012-12-28 | Санофи-Авентис | ПРОИЗВОДНЫЕ 2-АРИЛ-6-ФЕНИЛИМИДАЗО[1,2-a]ПИРИДИНОВ, ИХ ПОЛУЧЕНИЕ И ПРИМЕНЕНИЕ В ТЕРАПИИ |
| WO2011057145A2 (en) * | 2009-11-05 | 2011-05-12 | University Of Notre Dame Du Lac | Imidazo[1,2-a] pyridine compounds, synthesis thereof, and methods of using same |
| WO2011113606A1 (en) * | 2010-03-18 | 2011-09-22 | Institut Pasteur Korea | Anti-infective compounds |
| WO2012143796A2 (en) * | 2011-04-21 | 2012-10-26 | Institut Pasteur Korea | Anti-inflammation compounds |
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| PH12016500207A1 (en) | 2016-04-25 |
| ES2883565T3 (es) | 2021-12-09 |
| EP3027615B1 (en) | 2021-07-21 |
| SG11201600686QA (en) | 2016-02-26 |
| KR20170082450A (ko) | 2017-07-14 |
| DK3027615T3 (da) | 2021-10-25 |
| JP6757768B2 (ja) | 2020-09-23 |
| WO2015014993A3 (en) | 2015-04-02 |
| JP2018158941A (ja) | 2018-10-11 |
| CN105745208A (zh) | 2016-07-06 |
| KR102292293B1 (ko) | 2021-08-23 |
| WO2015014993A2 (en) | 2015-02-05 |
| HUE056198T2 (hu) | 2022-02-28 |
| US20160185774A1 (en) | 2016-06-30 |
| CN109575018A (zh) | 2019-04-05 |
| RU2016107378A3 (https=) | 2018-03-29 |
| RU2016107378A (ru) | 2017-09-07 |
| JP2019131606A (ja) | 2019-08-08 |
| EP3027615A2 (en) | 2016-06-08 |
| JP2016525562A (ja) | 2016-08-25 |
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