KR102292293B1 - 항감염성 화합물 - Google Patents

항감염성 화합물 Download PDF

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KR102292293B1
KR102292293B1 KR1020167005457A KR20167005457A KR102292293B1 KR 102292293 B1 KR102292293 B1 KR 102292293B1 KR 1020167005457 A KR1020167005457 A KR 1020167005457A KR 20167005457 A KR20167005457 A KR 20167005457A KR 102292293 B1 KR102292293 B1 KR 102292293B1
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chloro
mmol
compound
ethyl
hydrogen
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Korean (ko)
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KR20170082450A (ko
Inventor
김재승
강선희
서민정
서무영
서정지
이수미
강주희
박동식
김양오
케빈 피터
남기연
김정준
오수현
이새연
안지예
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재단법인 한국파스퇴르연구소
주식회사 큐리언트
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020167005457A 2013-08-02 2014-08-01 항감염성 화합물 Active KR102292293B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361861750P 2013-08-02 2013-08-02
US61/861,750 2013-08-02
PCT/EP2014/066614 WO2015014993A2 (en) 2013-08-02 2014-08-01 Anti-infective compounds

Publications (2)

Publication Number Publication Date
KR20170082450A KR20170082450A (ko) 2017-07-14
KR102292293B1 true KR102292293B1 (ko) 2021-08-23

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KR1020167005457A Active KR102292293B1 (ko) 2013-08-02 2014-08-01 항감염성 화합물

Country Status (12)

Country Link
US (1) US20160185774A1 (https=)
EP (1) EP3027615B1 (https=)
JP (3) JP2016525562A (https=)
KR (1) KR102292293B1 (https=)
CN (2) CN109575018A (https=)
DK (1) DK3027615T3 (https=)
ES (1) ES2883565T3 (https=)
HU (1) HUE056198T2 (https=)
PH (1) PH12016500207A1 (https=)
RU (1) RU2734760C2 (https=)
SG (1) SG11201600686QA (https=)
WO (1) WO2015014993A2 (https=)

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UA125171C2 (uk) 2015-07-02 2022-01-26 Янссен Саєнсиз Айрленд Юсі Антибактеріальні сполуки
KR20180053386A (ko) * 2015-09-17 2018-05-21 마빈 제이. 밀러 마이코박테리아 감염에 대해 유용한 벤질 아민-함유 헤테로사이클릭 화합물 및 조성물
JP2019518046A (ja) * 2016-06-16 2019-06-27 ヤンセン・サイエンシズ・アイルランド・アンリミテッド・カンパニー 抗菌薬としての複素環式化合物
US20200308169A1 (en) 2016-06-16 2020-10-01 Janssen Sciences Ireland Unlimited Company Heterocyclic compounds as antibacterials
KR20190121315A (ko) 2017-03-01 2019-10-25 얀센 사이언시즈 아일랜드 언리미티드 컴퍼니 병용 요법
CN111246848A (zh) * 2017-10-05 2020-06-05 快尔生物技术公司 与抗结核药物组合的环稠和的噻唑并2-吡啶酮
CN108101828B (zh) * 2018-01-15 2021-05-04 西华师范大学 3-吲哚基甲酰胺类化合物及其制备方法
CN108159049B (zh) * 2018-02-01 2021-01-05 中国科学院广州生物医药与健康研究院 一种吡啶类化合物的新用途
WO2020113094A1 (en) 2018-11-30 2020-06-04 Nuvation Bio Inc. Pyrrole and pyrazole compounds and methods of use thereof
JPWO2020203609A1 (https=) * 2019-03-29 2020-10-08
JP2022081710A (ja) * 2019-03-29 2022-06-01 ユーティアイ リミテッド パートナーシップ 関節リウマチを治療するためのｔ型カルシウムチャネル阻害剤の使用
TWI861208B (zh) * 2019-09-10 2024-11-11 日商鹽野義製藥股份有限公司 對分枝桿菌感染有用之含苄胺的 5,6-雜芳族化合物
US20220340564A1 (en) 2019-09-13 2022-10-27 Janssen Sciences Ireland Unlimited Company Antibacterial compounds
CN114450288A (zh) * 2019-09-30 2022-05-06 爱尔兰詹森科学公司 4-喹啉酮抗细菌化合物
MX2022003816A (es) * 2019-09-30 2022-05-06 Janssen Sciences Ireland Unlimited Co Compuestos antibacterianos.
KR102381397B1 (ko) * 2020-07-10 2022-03-30 경희대학교 산학협력단 신규 나프토퀴논 유도체 화합물 및 이를 포함하는 항균용 조성물
MX2023010947A (es) 2021-03-16 2023-11-29 Janssen Sciences Ireland Unlimited Co Compuestos antibacterianos.
MX2023010941A (es) 2021-03-17 2023-11-28 Janssen Sciences Ireland Unlimited Co Compuestos antibacterianos.
CA3211592A1 (en) 2021-03-17 2022-09-22 Jerome Emile Georges Guillemont Antibacterial compounds
EP4423097A1 (en) 2021-10-28 2024-09-04 Janssen Sciences Ireland Unlimited Company Imidazopyridine amides and related compounds for use in the treatment of bacterial infections
JP2025530847A (ja) * 2022-09-16 2025-09-17 北京華益健康薬物研究中心 Ｍｅｔｔｌ３阻害剤化合物、その医薬組成物及び用途
WO2024089170A1 (en) 2022-10-27 2024-05-02 Janssen Sciences Ireland Unlimited Company Antibacterial compounds
WO2024223859A1 (en) 2023-04-26 2024-10-31 Janssen Pharmaceutica Nv Antibacterial compounds
KR20260041840A (ko) 2023-07-18 2026-03-27 얀센 파마슈티카 엔브이 베다퀼린, 프레토마니드 또는 델라마니드, 및 시토크롬 bc1 억제제를 포함하는 적어도 세 가지 항생제의 조합 제품 및 미코박테리아 감염 치료에서의 이들의 용도
CN117946118A (zh) * 2024-01-15 2024-04-30 珃诺生物医药科技(杭州)有限公司 一种靶向降解erk5蛋白的化合物及其制备方法

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FR2906250B1 (fr) * 2006-09-22 2008-10-31 Sanofi Aventis Sa Derives de 2-aryl-6phenyl-imidazo(1,2-a) pyridines, leur preparation et leur application en therapeutique
US20100298314A1 (en) * 2006-12-20 2010-11-25 Schering Corporation Novel jnk inhibitors
WO2009140101A2 (en) * 2008-05-12 2009-11-19 Boehringer Ingelheim International Gmbh Imidazopyridine compounds useful as mmp-13 inhibitors
EP2496578A4 (en) * 2009-11-05 2013-08-21 Univ Notre Dame Du Lac IMIDAZO [1,2-A] PYRIDINE COMPOUNDS, THEIR SYNTHESIS AND METHODS OF USE THEREOF
SG184073A1 (en) * 2010-03-18 2012-10-30 Pasteur Institut Korea Anti-infective compounds
KR20140093610A (ko) * 2011-04-21 2014-07-28 재단법인 한국파스퇴르연구소 소염 화합물
CN103324035B (zh) * 2013-06-20 2015-07-01 深圳市华星光电技术有限公司 掩膜板和阵列基板的制作方法

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Publication number Publication date
PH12016500207A1 (en) 2016-04-25
ES2883565T3 (es) 2021-12-09
EP3027615B1 (en) 2021-07-21
SG11201600686QA (en) 2016-02-26
RU2734760C2 (ru) 2020-10-23
KR20170082450A (ko) 2017-07-14
DK3027615T3 (da) 2021-10-25
JP6757768B2 (ja) 2020-09-23
WO2015014993A3 (en) 2015-04-02
JP2018158941A (ja) 2018-10-11
CN105745208A (zh) 2016-07-06
WO2015014993A2 (en) 2015-02-05
HUE056198T2 (hu) 2022-02-28
US20160185774A1 (en) 2016-06-30
CN109575018A (zh) 2019-04-05
RU2016107378A3 (https=) 2018-03-29
RU2016107378A (ru) 2017-09-07
JP2019131606A (ja) 2019-08-08
EP3027615A2 (en) 2016-06-08
JP2016525562A (ja) 2016-08-25

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