RU2689388C1 - Пептидомиметические соединения и их конъюгаты антител с лекарственными средствами - Google Patents

Пептидомиметические соединения и их конъюгаты антител с лекарственными средствами Download PDF

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RU2689388C1
RU2689388C1 RU2016122504A RU2016122504A RU2689388C1 RU 2689388 C1 RU2689388 C1 RU 2689388C1 RU 2016122504 A RU2016122504 A RU 2016122504A RU 2016122504 A RU2016122504 A RU 2016122504A RU 2689388 C1 RU2689388 C1 RU 2689388C1
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antibody
amino acid
drug
acid sequence
seq
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RU2016122504A
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Russian (ru)
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Джон ФЛИГАРЕ
Джанет ГУНЗНЕР-ТОСТЕ
Томас Пиллоу
Брайан САФИНА
Вишал Верма
Бинкинг УЭЙ
Гуилинг ЧЖАО
Леанна Стабен
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Дженентек, Инк.
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  • Diabetes (AREA)
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RU2016122504A 2013-12-16 2014-12-16 Пептидомиметические соединения и их конъюгаты антител с лекарственными средствами RU2689388C1 (ru)

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US201361916680P 2013-12-16 2013-12-16
US61/916,680 2013-12-16
PCT/US2014/070654 WO2015095223A2 (en) 2013-12-16 2014-12-16 Peptidomimetic compounds and antibody-drug conjugates thereof

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US (1) US9999681B2 (OSRAM)
EP (1) EP3082874A2 (OSRAM)
JP (1) JP6671292B2 (OSRAM)
KR (1) KR102354207B1 (OSRAM)
CN (1) CN105873614B (OSRAM)
BR (1) BR112016012410A2 (OSRAM)
CA (1) CA2928952A1 (OSRAM)
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HK1222577A1 (zh) 2013-12-16 2017-07-07 Genentech Inc. 擬肽化合物及其抗體藥物偶聯物
EA201691023A1 (ru) 2013-12-16 2016-10-31 Дженентек, Инк. Пептидомиметические соединения и их конъюгаты антитела с лекарственным средством
CR20170095A (es) 2014-09-12 2017-07-19 Genentech Inc Anticuerpos anti-cll-1 e inmunoconjugados referencias recíprocas con solicitudes relacionadas
MX2017003123A (es) 2014-09-12 2017-05-12 Genentech Inc Anticuerpos y conjugados modificados geneticamente con cisteina.
JP6752204B2 (ja) * 2014-12-03 2020-09-09 ジェネンテック， インコーポレイテッド 四級アミン化合物及びその抗体−薬物コンジュゲート
EP3307780A1 (en) 2015-06-15 2018-04-18 Genentech, Inc. Antibodies and immunoconjugates
MA43345A (fr) * 2015-10-02 2018-08-08 Hoffmann La Roche Conjugués anticorps-médicaments de pyrrolobenzodiazépine et méthodes d'utilisation
ES2858151T3 (es) * 2016-05-20 2021-09-29 Hoffmann La Roche Conjugados de PROTAC-anticuerpo y procedimientos de uso
US20170370906A1 (en) 2016-05-27 2017-12-28 Genentech, Inc. Bioanalytical analysis of site-specific antibody drug conjugates
US10668166B2 (en) 2016-05-30 2020-06-02 Toxinvent Ou Antibody-drug-conjugates comprising novel anthracycline-derivatives for cancer treatment
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