RU2633505C2 - Фармацевтическая композиция для лечения и/или профилактики рака - Google Patents
Фармацевтическая композиция для лечения и/или профилактики рака Download PDFInfo
- Publication number
- RU2633505C2 RU2633505C2 RU2014138038A RU2014138038A RU2633505C2 RU 2633505 C2 RU2633505 C2 RU 2633505C2 RU 2014138038 A RU2014138038 A RU 2014138038A RU 2014138038 A RU2014138038 A RU 2014138038A RU 2633505 C2 RU2633505 C2 RU 2633505C2
- Authority
- RU
- Russia
- Prior art keywords
- antibody
- caprin
- cancer
- seq
- antibodies
- Prior art date
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
- C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- Endocrinology (AREA)
- Mycology (AREA)
- Cell Biology (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2012035491 | 2012-02-21 | ||
JP2012-035491 | 2012-02-21 | ||
PCT/JP2013/054345 WO2013125640A1 (ja) | 2012-02-21 | 2013-02-21 | 癌の治療及び/又は予防用医薬組成物 |
Publications (2)
Publication Number | Publication Date |
---|---|
RU2014138038A RU2014138038A (ru) | 2016-04-10 |
RU2633505C2 true RU2633505C2 (ru) | 2017-10-12 |
Family
ID=49005817
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RU2014138038A RU2633505C2 (ru) | 2012-02-21 | 2013-02-21 | Фармацевтическая композиция для лечения и/или профилактики рака |
Country Status (17)
Country | Link |
---|---|
US (1) | US9266958B2 (forum.php) |
EP (1) | EP2824114B1 (forum.php) |
JP (1) | JP6187258B2 (forum.php) |
KR (1) | KR102009236B1 (forum.php) |
CN (1) | CN104114583B (forum.php) |
AU (1) | AU2013223147B2 (forum.php) |
BR (1) | BR112014021103A2 (forum.php) |
CA (1) | CA2865020C (forum.php) |
DK (1) | DK2824114T3 (forum.php) |
ES (1) | ES2739380T3 (forum.php) |
HU (1) | HUE045461T2 (forum.php) |
IN (1) | IN2014KN01716A (forum.php) |
MX (1) | MX360211B (forum.php) |
PL (1) | PL2824114T3 (forum.php) |
PT (1) | PT2824114T (forum.php) |
RU (1) | RU2633505C2 (forum.php) |
WO (1) | WO2013125640A1 (forum.php) |
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PT2325648E (pt) | 2008-08-05 | 2014-06-24 | Toray Industries | Método para detetar cancro |
ES2540858T3 (es) * | 2010-02-04 | 2015-07-14 | Toray Industries, Inc. | Composición farmacéutica para el tratamiento y/o la prevención de cáncer |
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CN103717238B (zh) * | 2011-08-04 | 2016-10-12 | 东丽株式会社 | 胰癌的治疗和/或预防用药物组合物 |
JP6187256B2 (ja) | 2012-02-21 | 2017-08-30 | 東レ株式会社 | 癌の治療及び/又は予防用医薬組成物 |
WO2013147169A1 (ja) * | 2012-03-30 | 2013-10-03 | 東レ株式会社 | 肝臓癌の治療及び/又は予防用医薬組成物 |
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DK3031826T3 (en) | 2013-08-09 | 2018-12-17 | Toray Industries | Pharmaceutical composition for the treatment and / or prevention of cancer |
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WO2018079740A1 (ja) | 2016-10-28 | 2018-05-03 | 東レ株式会社 | 癌の治療及び/又は予防用医薬組成物 |
AU2019242520A1 (en) | 2018-03-30 | 2020-10-29 | Toray Industries, Inc. | Pharmaceutical composition for treatment and/or prevention of cancer |
EP3937984A1 (en) | 2019-03-15 | 2022-01-19 | Bolt Biotherapeutics, Inc. | Immunoconjugates targeting her2 |
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JP2022549510A (ja) | 2019-09-30 | 2022-11-25 | ボルト バイオセラピューティクス、インコーポレーテッド | アミド結合したアミノベンズアゼピン免疫複合体、及びその使用 |
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US20230139178A1 (en) | 2020-03-12 | 2023-05-04 | Toray Industries, Inc. | Medicament for treatment and/or prevention of cancer |
JP7715041B2 (ja) | 2020-03-12 | 2025-07-30 | 東レ株式会社 | 癌の治療及び/又は予防のための医薬品 |
KR20220152318A (ko) | 2020-03-12 | 2022-11-15 | 도레이 카부시키가이샤 | 암의 치료 및/또는 예방을 위한 의약품 |
BR112022018161A2 (pt) | 2020-03-12 | 2022-10-25 | Toray Industries | Medicamento para o tratamento e/ou prevenção do câncer, agentes que aumentam a eficácia de um fármaco e método para o tratamento e/ou prevenção do câncer |
CA3175129A1 (en) | 2020-03-12 | 2021-09-19 | Toray Industries, Inc. | Medicament for treatment and/or prevention of cancer |
US20230293716A1 (en) | 2020-05-08 | 2023-09-21 | Bolt Biotherapeutics, Inc. | Elastase-substrate, peptide linker immunoconjugates, and uses thereof |
IL300316A (en) | 2020-08-13 | 2023-04-01 | Bolt Biotherapeutics Inc | Immune conjugates of pyrazolozapines and their uses |
JPWO2022270523A1 (forum.php) | 2021-06-23 | 2022-12-29 | ||
BR112023026992A2 (pt) | 2021-06-23 | 2024-03-12 | Toray Industries | Medicamento para o tratamento e/ou prevenção do câncer, agentes que aumentam a eficácia do medicamento em uma composição farmacêutica e método para tratar e/ou prevenir o câncer |
CN117693363A (zh) | 2021-07-27 | 2024-03-12 | 东丽株式会社 | 用于癌的治疗和/或预防的药品 |
AU2022316644A1 (en) | 2021-07-27 | 2024-02-29 | Toray Industries, Inc. | Medicament for treatment and/or prevention of cancer |
WO2023008462A1 (ja) | 2021-07-27 | 2023-02-02 | 東レ株式会社 | 癌の治療及び/又は予防のための医薬品 |
CA3230737A1 (en) | 2021-09-03 | 2023-03-09 | Toray Industries, Inc. | Pharmaceutical composition for cancer treatment and/or prevention |
CN118475372A (zh) | 2021-10-29 | 2024-08-09 | 博尔特生物治疗药物有限公司 | 具有半胱氨酸突变抗体的tlr激动剂免疫缀合物及其用途 |
KR20250031149A (ko) | 2022-06-30 | 2025-03-06 | 도레이 카부시키가이샤 | 암의 치료 및/또는 예방용 의약 조성물 |
KR20250052369A (ko) | 2022-08-24 | 2025-04-18 | 도레이 카부시키가이샤 | 암의 치료 및/또는 예방을 위한 의약품 |
KR20250052364A (ko) | 2022-08-24 | 2025-04-18 | 도레이 카부시키가이샤 | 암의 치료 및/또는 예방을 위한 의약품 |
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AU2023411604A1 (en) | 2022-12-23 | 2025-06-26 | Toray Industries, Inc. | Medicament for treatment and/or prevention of cancer |
WO2024173384A1 (en) | 2023-02-14 | 2024-08-22 | Bolt Biotherapeutics, Inc. | Aza-benzazepine immunoconjugates, and uses thereof |
WO2024186626A1 (en) | 2023-03-03 | 2024-09-12 | Bolt Biotherapeutics, Inc. | Aza-bicyclic sting agonist immunoconjugates, and uses thereof |
Citations (3)
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Publication number | Publication date |
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EP2824114B1 (en) | 2019-05-22 |
BR112014021103A8 (pt) | 2018-01-23 |
AU2013223147A1 (en) | 2014-09-11 |
CA2865020A1 (en) | 2013-08-29 |
CN104114583B (zh) | 2019-11-19 |
EP2824114A1 (en) | 2015-01-14 |
BR112014021103A2 (pt) | 2019-10-15 |
CN104114583A (zh) | 2014-10-22 |
CA2865020C (en) | 2021-01-26 |
ES2739380T3 (es) | 2020-01-30 |
WO2013125640A1 (ja) | 2013-08-29 |
HUE045461T2 (hu) | 2019-12-30 |
PL2824114T3 (pl) | 2019-11-29 |
RU2014138038A (ru) | 2016-04-10 |
KR20140130671A (ko) | 2014-11-11 |
MX360211B (es) | 2018-10-24 |
US20150017172A1 (en) | 2015-01-15 |
DK2824114T3 (da) | 2019-07-29 |
AU2013223147B2 (en) | 2017-10-05 |
JPWO2013125640A1 (ja) | 2015-07-30 |
PT2824114T (pt) | 2019-08-05 |
IN2014KN01716A (forum.php) | 2015-10-23 |
EP2824114A4 (en) | 2015-10-07 |
JP6187258B2 (ja) | 2017-08-30 |
MX2014009749A (es) | 2014-11-14 |
KR102009236B1 (ko) | 2019-08-09 |
US9266958B2 (en) | 2016-02-23 |
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