RU2620563C2 - Способ детекции партнера по связыванию мультиспецифического связывающего агента - Google Patents

Способ детекции партнера по связыванию мультиспецифического связывающего агента Download PDF

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RU2620563C2
RU2620563C2 RU2014133701A RU2014133701A RU2620563C2 RU 2620563 C2 RU2620563 C2 RU 2620563C2 RU 2014133701 A RU2014133701 A RU 2014133701A RU 2014133701 A RU2014133701 A RU 2014133701A RU 2620563 C2 RU2620563 C2 RU 2620563C2
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antibody
antigen
sample
bispecific antibody
binding
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RU2014133701A
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English (en)
Russian (ru)
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RU2014133701A (ru
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Кай-Гуннар ШТУБЕНРАУХ
Уве ВЕССЕЛЬС
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Ф. Хоффманн-Ля Рош Аг
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306—Solid-phase reaction mechanisms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
RU2014133701A 2012-02-01 2013-01-29 Способ детекции партнера по связыванию мультиспецифического связывающего агента RU2620563C2 (ru)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP12153457.2 2012-02-01
EP12153457 2012-02-01
EP12182505.3 2012-08-31
EP12182505 2012-08-31
PCT/EP2013/051604 WO2013113663A1 (en) 2012-02-01 2013-01-29 Method for the detection of a binding partner of a multispecific binder

Publications (2)

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RU2014133701A RU2014133701A (ru) 2016-03-27
RU2620563C2 true RU2620563C2 (ru) 2017-05-26

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US (3) US9945869B2 (US20080131398A1-20080605-C00009.png)
EP (1) EP2810074B1 (US20080131398A1-20080605-C00009.png)
JP (3) JP2015507193A (US20080131398A1-20080605-C00009.png)
KR (1) KR20140128314A (US20080131398A1-20080605-C00009.png)
CN (2) CN104105966B (US20080131398A1-20080605-C00009.png)
BR (1) BR112014017630A8 (US20080131398A1-20080605-C00009.png)
CA (1) CA2859268A1 (US20080131398A1-20080605-C00009.png)
HK (1) HK1202921A1 (US20080131398A1-20080605-C00009.png)
MX (1) MX349661B (US20080131398A1-20080605-C00009.png)
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JP6446044B2 (ja) 2013-11-05 2018-12-26 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ 結合分子の存在下で被検体の総量および／または総濃度を決定するための方法、ならびにそれに関係するキット、組成物および使用
CN104109197B (zh) * 2013-11-13 2017-05-10 叶森 一种双识别抗体片段的制备方法及其应用
CN108139394B (zh) 2015-10-02 2020-10-30 豪夫迈·罗氏有限公司 用于确定同时结合的基于细胞的fret测定法
AU2016329126B2 (en) 2015-10-02 2023-04-13 F. Hoffmann-La Roche Ag Bispecific antibodies specific for PD1 and TIM3
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KR102408873B1 (ko) 2017-04-05 2022-06-15 에프. 호프만-라 로슈 아게 Pd1 및 lag3에 특이적으로 결합하는 이중특이적 항체
EP3805757A4 (en) 2018-06-04 2022-03-23 Chugai Seiyaku Kabushiki Kaisha METHOD FOR DETECTING A COMPLEX
CN113811770B (zh) * 2019-05-13 2024-06-28 豪夫迈·罗氏有限公司 抑制干扰的药代动力学免疫测定
WO2022065052A1 (ja) * 2020-09-24 2022-03-31 株式会社Ｊｖｃケンウッド 捕捉用抗体、固相担体、検出用抗体、固相担体粒子、並びに検出対象物質の測定キット及び測定方法
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Also Published As

Publication number Publication date
EP2810074A1 (en) 2014-12-10
JP6678792B2 (ja) 2020-04-08
US10761097B2 (en) 2020-09-01
HK1202921A1 (en) 2015-10-09
CN104105966B (zh) 2016-10-26
MX349661B (es) 2017-08-08
RU2014133701A (ru) 2016-03-27
JP2015507193A (ja) 2015-03-05
US20140342382A1 (en) 2014-11-20
JP6502441B2 (ja) 2019-04-17
CN104105966A (zh) 2014-10-15
MX2014008762A (es) 2014-08-27
JP2019113564A (ja) 2019-07-11
US20180328942A1 (en) 2018-11-15
EP2810074B1 (en) 2017-08-23
BR112014017630A2 (US20080131398A1-20080605-C00009.png) 2017-06-20
CN106443016B (zh) 2019-08-13
BR112014017630A8 (pt) 2017-07-11
US9945869B2 (en) 2018-04-17
KR20140128314A (ko) 2014-11-05
CA2859268A1 (en) 2013-08-08
CN106443016A (zh) 2017-02-22
WO2013113663A1 (en) 2013-08-08
JP2017223710A (ja) 2017-12-21
US20210055304A1 (en) 2021-02-25

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