RU2603089C2 - Рекомбинантный микроорганизм, обладающий повышенной способностью продуцировать путресцин, и способ получения путресцина с использованием этого микроорганизма - Google Patents

Рекомбинантный микроорганизм, обладающий повышенной способностью продуцировать путресцин, и способ получения путресцина с использованием этого микроорганизма Download PDF

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RU2603089C2
RU2603089C2 RU2014133769/10A RU2014133769A RU2603089C2 RU 2603089 C2 RU2603089 C2 RU 2603089C2 RU 2014133769/10 A RU2014133769/10 A RU 2014133769/10A RU 2014133769 A RU2014133769 A RU 2014133769A RU 2603089 C2 RU2603089 C2 RU 2603089C2
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putrescine
seq
microorganism
activity
ncgl0101
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RU2014133769/10A
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Russian (ru)
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RU2014133769A (ru
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Кьоунг Мин ЛИ
Сеон Хье КИМ
Хье Вон УМ
Мин Сун КАНГ
Су Джин ЧОЙ
Хи Кьюн ДЖУН
Сун Ху ДЖОН
Хонсян ЛИ
Вон Сик ГВАК
Чон Хо ЛИ
Юнг Леол ЯНГ
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СиДжей ЧеилДжеданг Корпорейшн
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/77—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Corynebacterium; for Brevibacterium
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/001—Amines; Imines
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/15—Corynebacterium

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
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  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
RU2014133769/10A 2012-01-20 2013-01-21 Рекомбинантный микроорганизм, обладающий повышенной способностью продуцировать путресцин, и способ получения путресцина с использованием этого микроорганизма RU2603089C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR10-2012-0007004 2012-01-20
KR20120007004 2012-01-20
PCT/KR2013/000487 WO2013109121A1 (ko) 2012-01-20 2013-01-21 퓨트레신 생산능이 향상된 재조합 미생물 및 이를 이용하여 퓨트레신을 생산하는 방법

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RU2014133769A RU2014133769A (ru) 2016-03-20
RU2603089C2 true RU2603089C2 (ru) 2016-11-20

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RU2014133769/10A RU2603089C2 (ru) 2012-01-20 2013-01-21 Рекомбинантный микроорганизм, обладающий повышенной способностью продуцировать путресцин, и способ получения путресцина с использованием этого микроорганизма

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US (1) US9290771B2 (enExample)
EP (1) EP2806022B1 (enExample)
JP (2) JP6251187B2 (enExample)
KR (1) KR101493586B1 (enExample)
AU (1) AU2013210136B2 (enExample)
BR (1) BR112014017910B1 (enExample)
DK (1) DK2806022T3 (enExample)
ES (1) ES2682696T3 (enExample)
IN (1) IN2014MN01621A (enExample)
MY (1) MY173018A (enExample)
PL (1) PL2806022T3 (enExample)
RU (1) RU2603089C2 (enExample)
TR (1) TR201810509T4 (enExample)
WO (1) WO2013109121A1 (enExample)

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KR101607741B1 (ko) * 2013-03-20 2016-03-31 씨제이제일제당 (주) 퓨트레신 생산 재조합 미생물 및 이를 이용한 퓨트레신 생산방법
ES2711857T3 (es) 2014-04-25 2019-05-07 Cj Cheiljedang Corp Cepa variante productora de putrescina y método de producción que la utiliza
KR101773135B1 (ko) * 2015-05-08 2017-08-30 씨제이제일제당 주식회사 1,4-디아미노부탄의 정제방법
WO2020138543A1 (ko) * 2018-12-27 2020-07-02 씨제이제일제당 (주) 오르니틴 탈탄산 효소의 변이주 및 그의 응용
WO2020138919A1 (ko) 2018-12-27 2020-07-02 씨제이제일제당(주) 오르니틴 탈탄산 효소 변이형 및 이를 이용한 퓨트레신 생산 방법

Citations (1)

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RU2433180C2 (ru) * 2008-04-10 2011-11-10 Корея Эдванст Инститьют Оф Сайенс Энд Текнолоджи Микроорганизм, обладающий способностью к продукции путресцина в высокой концентрации, способ получения этого микроорганизма и способ продукции путресцина с использованием этого микроорганизма

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KR920007401B1 (ko) 1990-06-21 1992-08-31 제일제당 주식회사 다발성 절단부위를 지닌 대장균과 코리네형 세균에서 발현 가능한 신규 셔틀벡터
BRPI0513343B1 (pt) * 2004-07-15 2020-11-03 Dsm Ip Assets B.V microrganismo transformado selecionado a partir da espécie escherichia coli (e.coli) e processo para síntese bioquímica de 1,4-butanodiamina a partir do referido microrganismo
KR100620092B1 (ko) 2004-12-16 2006-09-08 씨제이 주식회사 코리네박테리움 속 세포로부터 유래된 신규한 프로모터서열, 그를 포함하는 발현 카세트 및 벡터, 상기 벡터를포함하는 숙주 세포 및 그를 이용하여 유전자를 발현하는방법
WO2008039293A2 (en) 2006-09-30 2008-04-03 Osram Sylvania Inc. Power supply and electronic ballast with auxiliary protection circuit
KR100860932B1 (ko) 2007-02-08 2008-09-29 씨제이제일제당 (주) 신규한 프로모터 및 이의 용도
KR101188432B1 (ko) * 2008-04-10 2012-10-08 한국과학기술원 퓨트레신 고생성능을 가지는 변이 미생물 및 이를 이용한 퓨트레신의 제조방법
KR101348461B1 (ko) 2010-12-08 2014-01-08 씨제이제일제당 (주) 퓨트레신을 생산하는 미생물 및 이를 이용하여 퓨트레신을 생산하는 방법

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RU2433180C2 (ru) * 2008-04-10 2011-11-10 Корея Эдванст Инститьют Оф Сайенс Энд Текнолоджи Микроорганизм, обладающий способностью к продукции путресцина в высокой концентрации, способ получения этого микроорганизма и способ продукции путресцина с использованием этого микроорганизма

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SCHNEIDER J. ET AL. Putrescine production by engineered Corynebacterium glutamicum // Appl Microbiol Biotechnol (2010) 88:859-868;. HASHIMOTO K. ET AL. The protein encoded by NCgl1221 in Corynebacterium glutamicum functions as a mechanosensitive channel // Biosci. Biotechnol. Biochem., 2010, 74(12), pp. 2546-2549. *

Also Published As

Publication number Publication date
PL2806022T3 (pl) 2018-12-31
EP2806022A1 (en) 2014-11-26
RU2014133769A (ru) 2016-03-20
AU2013210136B2 (en) 2016-07-07
JP2017006133A (ja) 2017-01-12
WO2013109121A1 (ko) 2013-07-25
IN2014MN01621A (enExample) 2015-07-03
DK2806022T3 (en) 2018-08-13
BR112014017910A2 (pt) 2017-11-28
CN104136600A (zh) 2014-11-05
MY173018A (en) 2019-12-19
KR20130086010A (ko) 2013-07-30
AU2013210136A1 (en) 2014-09-11
EP2806022B1 (en) 2018-05-23
KR101493586B1 (ko) 2015-02-16
JP6251187B2 (ja) 2017-12-20
JP2015506686A (ja) 2015-03-05
BR112014017910B1 (pt) 2022-04-26
ES2682696T3 (es) 2018-09-21
EP2806022A4 (en) 2015-10-07
US9290771B2 (en) 2016-03-22
US20140363859A1 (en) 2014-12-11
TR201810509T4 (tr) 2018-08-27

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