RU2571224C2 - Гуманизированные антитела против axl - Google Patents
Гуманизированные антитела против axl Download PDFInfo
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- RU2571224C2 RU2571224C2 RU2011150183/10A RU2011150183A RU2571224C2 RU 2571224 C2 RU2571224 C2 RU 2571224C2 RU 2011150183/10 A RU2011150183/10 A RU 2011150183/10A RU 2011150183 A RU2011150183 A RU 2011150183A RU 2571224 C2 RU2571224 C2 RU 2571224C2
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- seq
- axl
- threonine
- serine
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| EP09006355A EP2270053A1 (en) | 2009-05-11 | 2009-05-11 | Humanized AXL antibodies |
| EP09006355.3 | 2009-05-11 | ||
| EP09006474.2 | 2009-05-13 | ||
| EP09006474 | 2009-05-13 | ||
| PCT/EP2010/056487 WO2010130751A1 (en) | 2009-05-11 | 2010-05-11 | Humanized axl antibodies |
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| RU2011150183A RU2011150183A (ru) | 2013-06-20 |
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| RU2011150183/10A RU2571224C2 (ru) | 2009-05-11 | 2010-05-11 | Гуманизированные антитела против axl |
| RU2015147287A RU2015147287A (ru) | 2009-05-11 | 2015-11-03 | Гуманизированные антитела против axl |
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| RU2015147287A RU2015147287A (ru) | 2009-05-11 | 2015-11-03 | Гуманизированные антитела против axl |
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| RU2678569C1 (ru) * | 2018-10-31 | 2019-01-30 | Гордейчук Владимир Евгеньевич | Способ подавления метастазирования опухолей |
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| US9879061B2 (en) | 2011-12-15 | 2018-01-30 | The Board Of Trustees Of The Leland Stanford Junior University | Inhibition of AXL/GAS6 signaling in the treatment of liver fibrosis |
| US9624308B2 (en) * | 2012-11-05 | 2017-04-18 | Pierre Fabre Medicament | Antigen binding proteins |
| ES2665323T7 (es) * | 2012-12-14 | 2023-06-15 | Univ Leland Stanford Junior | Péptidos de AXL modificados y su uso en la inhibición de la señalización de AXL en terapia anti-metastásica |
| WO2016091891A1 (en) * | 2014-12-09 | 2016-06-16 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Human monoclonal antibodies against axl |
| US10208121B2 (en) | 2014-12-18 | 2019-02-19 | Bergen Teknologioverforing As | Anti-Axl antagonistic antibodies |
| GB201506411D0 (en) * | 2015-04-15 | 2015-05-27 | Bergenbio As | Humanized anti-axl antibodies |
| US10787517B2 (en) | 2015-05-18 | 2020-09-29 | Agensys, Inc. | Antibodies that bind to AXL proteins |
| EP3297662A4 (en) | 2015-05-18 | 2019-03-13 | Agensys, Inc. | ANTIBODIES BINDING TO AXL PROTEINS |
| GB201509338D0 (en) | 2015-05-29 | 2015-07-15 | Bergenbio As | Combination therapy |
| US20180326084A1 (en) | 2015-07-10 | 2018-11-15 | Genmab A/S | Axl-specific antibody-drug conjugates for cancer treatment |
| PL3354729T3 (pl) | 2015-09-24 | 2024-05-20 | Daiichi Sankyo Company, Limited | Przeciwciało anty-garp |
| KR20180126079A (ko) * | 2016-04-15 | 2018-11-26 | 바이오아트라, 엘엘씨 | 항 Axl항체, 항체 단편 및 이의 면역접합체와 이것들의 용도 |
| GB201610902D0 (en) | 2016-06-22 | 2016-08-03 | Bergen Teknologioverforing As And Bergenbio As | Anti-Axl Antagonistic Antibodies |
| MX2019012464A (es) | 2017-04-20 | 2019-12-11 | Adc Therapeutics Sa | Terapia combinada con un conjugado de anticuerpo y farmaco anti-axl. |
| CN110540592B (zh) | 2018-05-29 | 2022-08-09 | 杭州尚健生物技术有限公司 | 结合axl蛋白的抗体及其应用 |
| CN109160941B (zh) * | 2018-09-29 | 2020-09-04 | 未名生物医药有限公司 | 蛋白序列17e11及其用途 |
| GB201912059D0 (en) | 2019-08-22 | 2019-10-09 | Bergenbio As | Combaination therapy of a patient subgroup |
| CN110982791A (zh) * | 2019-12-26 | 2020-04-10 | 百泰生物药业有限公司 | 一种分泌axl抗体的杂交瘤细胞的制备筛选方法 |
| CA3164037A1 (en) | 2020-01-08 | 2021-07-15 | Synthis Therapeutics, Inc. | Alk5 inhibitor conjugates and uses thereof |
| GB202004189D0 (en) | 2020-03-23 | 2020-05-06 | Bergenbio As | Combination therapy |
| KR20230013241A (ko) | 2020-04-08 | 2023-01-26 | 베르겐바이오 에이에스에이 | 항바이러스 요법을 위한 axl 억제제 |
| GB202006072D0 (en) | 2020-04-24 | 2020-06-10 | Bergenbio Asa | Method of selecting patients for treatment with cmbination therapy |
| CA3205570A1 (en) | 2021-01-29 | 2022-08-04 | Chan Hyuk Kim | Fusion molecule having non-inflammatory phagocytosis inducing activity |
| GB202104037D0 (en) | 2021-03-23 | 2021-05-05 | Bergenbio Asa | Combination therapy |
| CN115927243A (zh) * | 2022-09-13 | 2023-04-07 | 中山大学 | 一种akt1蛋白的抑制性磷酸化位点及其应用 |
| CN116715774B (zh) * | 2023-05-12 | 2023-11-24 | 武汉爱博泰克生物科技有限公司 | 针对人axl的兔单克隆抗体及其制备方法和应用 |
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- 2010-05-11 TW TW103142582A patent/TWI526223B/zh not_active IP Right Cessation
- 2010-05-11 TW TW099114946A patent/TW201105348A/zh unknown
- 2010-05-11 RU RU2011150183/10A patent/RU2571224C2/ru not_active IP Right Cessation
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- 2010-05-11 MX MX2011011825A patent/MX2011011825A/es active IP Right Grant
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- 2010-05-11 EP EP10718217A patent/EP2430050A1/en not_active Withdrawn
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2014
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2015
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|---|---|---|---|---|
| RU2678569C1 (ru) * | 2018-10-31 | 2019-01-30 | Гордейчук Владимир Евгеньевич | Способ подавления метастазирования опухолей |
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| US20150037323A1 (en) | 2015-02-05 |
| TW201105348A (en) | 2011-02-16 |
| JP5909442B2 (ja) | 2016-04-26 |
| AU2010247464A1 (en) | 2011-11-10 |
| EP2430050A1 (en) | 2012-03-21 |
| MX2011011825A (es) | 2011-12-06 |
| IL216147A (en) | 2016-04-21 |
| CN102421802B (zh) | 2014-08-20 |
| WO2010130751A1 (en) | 2010-11-18 |
| JP2016011306A (ja) | 2016-01-21 |
| CA2759836A1 (en) | 2010-11-18 |
| IL216147A0 (en) | 2012-01-31 |
| AU2010247464B2 (en) | 2014-09-11 |
| RU2011150183A (ru) | 2013-06-20 |
| US8841424B2 (en) | 2014-09-23 |
| ZA201107529B (en) | 2012-06-27 |
| AR076564A1 (es) | 2011-06-22 |
| CN102421802A (zh) | 2012-04-18 |
| JP2012526530A (ja) | 2012-11-01 |
| KR20120035145A (ko) | 2012-04-13 |
| TWI526223B (zh) | 2016-03-21 |
| RU2015147287A (ru) | 2017-05-12 |
| BRPI1013428A2 (pt) | 2019-07-02 |
| TW201509431A (zh) | 2015-03-16 |
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