RU2529797C2 - Раковый маркер и терапевтическая мишень - Google Patents

Раковый маркер и терапевтическая мишень Download PDF

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RU2529797C2
RU2529797C2 RU2010123921/15A RU2010123921A RU2529797C2 RU 2529797 C2 RU2529797 C2 RU 2529797C2 RU 2010123921/15 A RU2010123921/15 A RU 2010123921/15A RU 2010123921 A RU2010123921 A RU 2010123921A RU 2529797 C2 RU2529797 C2 RU 2529797C2
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tumor
ccr4
cells
cancer
solid tumor
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RU2010123921/15A
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Russian (ru)
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RU2010123921A (ru
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Фрэнсис БЭЛКВИЛЛ
Вайолет СЛЭТТЕНААР
Джулия УИЛСОН
Яохэ ВАН
Тициана СКЬОППА
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Кэнсер Рисёч Текнолоджи Лтд
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Application filed by Кэнсер Рисёч Текнолоджи Лтд filed Critical Кэнсер Рисёч Текнолоджи Лтд
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/5758Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites
    • G01N33/5759Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites involving compounds localised on the membrane of tumour or cancer cells
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/72Assays involving receptors, cell surface antigens or cell surface determinants for hormones
    • G01N2333/726G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/52Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/56Staging of a disease; Further complications associated with the disease

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Oncology (AREA)
RU2010123921/15A 2007-09-18 2008-09-18 Раковый маркер и терапевтическая мишень RU2529797C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0718167A GB0718167D0 (en) 2007-09-18 2007-09-18 Cancer marker and therapeutic target
GB0718167.0 2007-09-18
PCT/GB2008/003160 WO2009037454A2 (en) 2007-09-18 2008-09-18 Cancer marker and therapeutic target

Related Child Applications (1)

Application Number Title Priority Date Filing Date
RU2014128513A Division RU2014128513A (ru) 2007-09-18 2014-07-14 Раковый маркер и терапевтическая мишень

Publications (2)

Publication Number Publication Date
RU2010123921A RU2010123921A (ru) 2011-12-20
RU2529797C2 true RU2529797C2 (ru) 2014-09-27

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RU2010123921/15A RU2529797C2 (ru) 2007-09-18 2008-09-18 Раковый маркер и терапевтическая мишень
RU2014128513A RU2014128513A (ru) 2007-09-18 2014-07-14 Раковый маркер и терапевтическая мишень

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RU2014128513A RU2014128513A (ru) 2007-09-18 2014-07-14 Раковый маркер и терапевтическая мишень

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US (2) US9134293B2 (enExample)
EP (3) EP2533047B1 (enExample)
JP (2) JP5774309B2 (enExample)
AU (1) AU2008300413B2 (enExample)
CA (1) CA2699702C (enExample)
DK (3) DK2533047T3 (enExample)
ES (3) ES2443541T3 (enExample)
GB (1) GB0718167D0 (enExample)
PL (3) PL2533047T3 (enExample)
RU (2) RU2529797C2 (enExample)
WO (1) WO2009037454A2 (enExample)

Cited By (2)

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Publication number Priority date Publication date Assignee Title
US20180125970A1 (en) * 2015-04-17 2018-05-10 Morphotek, Inc. Methods for treating lung cancer
RU2740254C2 (ru) * 2014-10-01 2021-01-12 Сфинготек Гмбх ОПРЕДЕЛЕНИЕ hGH ДЛЯ ПРИМЕНЕНИЯ ДЛЯ ПРЕДУПРЕЖДЕНИЯ ТЯЖЕЛОГО НЕБЛАГОПРИЯТНОГО СЕРДЕЧНО-СОСУДИСТОГО ЯВЛЕНИЯ ИЛИ СЕРДЕЧНО-СОСУДИСТОГО ЗАБОЛЕВАНИЯ У ИНДИВИДУУМА

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US10266599B2 (en) 2010-12-07 2019-04-23 Cancer Research Technology Limited Antibodies which bind to the human CC chemokine receptor 4 and uses thereof
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AU2015266958A1 (en) 2014-05-28 2016-12-08 Agenus Inc. Anti-GITR antibodies and methods of use thereof
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JP7177445B2 (ja) 2017-05-19 2022-11-24 真吾 前田 Ccr4阻害による制御性t細胞浸潤抑制法およびイヌの腫瘍性疾患の治療法
KR102817790B1 (ko) 2018-08-29 2025-06-05 케모센트릭스, 인크. C-c 케모카인 수용체 4(ccr4) 길항제 및 하나 이상의 면역 체크포인트 억제제를 사용한 병용 요법
EP3885452A1 (en) * 2020-03-23 2021-09-29 Koninklijke Philips N.V. Prediction of radiotherapy response for prostate cancer subject based on chemokine genes

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US20070149449A1 (en) * 2003-02-14 2007-06-28 Morris David W Therapeutic targets in cancer
RU2296328C1 (ru) * 2005-09-21 2007-03-27 Общество с ограниченной ответственностью "ГЕН" Способ определения предрасположенности к онкологическим заболеваниям и диагностический набор для его осуществления

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2740254C2 (ru) * 2014-10-01 2021-01-12 Сфинготек Гмбх ОПРЕДЕЛЕНИЕ hGH ДЛЯ ПРИМЕНЕНИЯ ДЛЯ ПРЕДУПРЕЖДЕНИЯ ТЯЖЕЛОГО НЕБЛАГОПРИЯТНОГО СЕРДЕЧНО-СОСУДИСТОГО ЯВЛЕНИЯ ИЛИ СЕРДЕЧНО-СОСУДИСТОГО ЗАБОЛЕВАНИЯ У ИНДИВИДУУМА
US20180125970A1 (en) * 2015-04-17 2018-05-10 Morphotek, Inc. Methods for treating lung cancer
RU2718780C2 (ru) * 2015-04-17 2020-04-14 Эйсай Инк. Способы лечения рака легкого
RU2718780C9 (ru) * 2015-04-17 2020-07-08 Эйсай Инк. Способы лечения рака легкого

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Publication number Publication date
GB0718167D0 (en) 2007-10-31
ES2443541T3 (es) 2014-02-19
RU2010123921A (ru) 2011-12-20
US20160223572A1 (en) 2016-08-04
CA2699702A1 (en) 2009-03-26
WO2009037454A3 (en) 2009-05-07
PL2533047T3 (pl) 2016-11-30
EP2533047A1 (en) 2012-12-12
PL2176664T3 (pl) 2014-04-30
DK2176664T3 (da) 2014-01-20
US9134293B2 (en) 2015-09-15
EP2535716A2 (en) 2012-12-19
EP2176664B1 (en) 2013-11-06
EP2535716A3 (en) 2013-03-13
EP2535716B1 (en) 2016-11-02
DK2535716T3 (en) 2017-02-13
EP2176664A2 (en) 2010-04-21
JP2015212703A (ja) 2015-11-26
AU2008300413B2 (en) 2014-09-11
EP2533047B1 (en) 2016-05-11
ES2588507T3 (es) 2016-11-03
JP2010539508A (ja) 2010-12-16
PL2535716T3 (pl) 2017-06-30
RU2014128513A (ru) 2016-02-10
US10261099B2 (en) 2019-04-16
JP6234967B2 (ja) 2017-11-22
CA2699702C (en) 2018-03-06
WO2009037454A2 (en) 2009-03-26
ES2612690T3 (es) 2017-05-18
AU2008300413A1 (en) 2009-03-26
DK2533047T3 (en) 2016-08-22
US20100278844A1 (en) 2010-11-04
JP5774309B2 (ja) 2015-09-09

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