RU2348418C2 - Введение дендритных клеток, подвергнутых частичному созреванию in vitro, для лечения опухолей - Google Patents

Введение дендритных клеток, подвергнутых частичному созреванию in vitro, для лечения опухолей Download PDF

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RU2348418C2
RU2348418C2 RU2005121256/14A RU2005121256A RU2348418C2 RU 2348418 C2 RU2348418 C2 RU 2348418C2 RU 2005121256/14 A RU2005121256/14 A RU 2005121256/14A RU 2005121256 A RU2005121256 A RU 2005121256A RU 2348418 C2 RU2348418 C2 RU 2348418C2
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tumor
dendritic cells
cells
partially matured
bcg
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RU2005121256A (ru
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Марникс Л. БОШ (US)
Марникс Л. БОШ
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Норсуэст Байотерапьютикс, Инк.
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    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/19—Dendritic cells
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/20—Cellular immunotherapy characterised by the effect or the function of the cells
    • A61K40/24—Antigen-presenting cells [APC]
    • A—HUMAN NECESSITIES
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    • A61K40/00—Cellular immunotherapy
    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41—Vertebrate antigens
    • A61K40/42—Cancer antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C12N5/12—Fused cells, e.g. hybridomas
    • C12N5/16—Animal cells
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
    • A61K2239/31—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterized by the route of administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
    • A61K2239/46—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterised by the cancer treated
    • A61K2239/50—Colon
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/24—Interferons [IFN]

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RU2005121256/14A 2002-12-06 2003-12-05 Введение дендритных клеток, подвергнутых частичному созреванию in vitro, для лечения опухолей RU2348418C2 (ru)

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US43126702P 2002-12-06 2002-12-06
US60/431,267 2002-12-06

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RU2005121256A RU2005121256A (ru) 2006-02-10
RU2348418C2 true RU2348418C2 (ru) 2009-03-10

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RU2005121256/14A RU2348418C2 (ru) 2002-12-06 2003-12-05 Введение дендритных клеток, подвергнутых частичному созреванию in vitro, для лечения опухолей

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US (2) US20060057120A1 (https=)
EP (2) EP2260861A1 (https=)
JP (2) JP4859169B2 (https=)
KR (1) KR101144196B1 (https=)
CN (2) CN102600461B (https=)
AT (1) ATE486125T1 (https=)
AU (2) AU2003293411B2 (https=)
BR (1) BRPI0317064B8 (https=)
CA (1) CA2509058A1 (https=)
DE (1) DE60334725D1 (https=)
DK (1) DK1567155T3 (https=)
ES (1) ES2354944T3 (https=)
IL (1) IL169002A (https=)
MX (1) MXPA05006042A (https=)
PL (1) PL377209A1 (https=)
PT (1) PT1567155E (https=)
RU (1) RU2348418C2 (https=)
WO (1) WO2004053072A2 (https=)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013147642A1 (ru) * 2012-03-29 2013-10-03 Egorov Oleg Borisovich Способ противоопухолевой иммунотерапии
RU2565542C2 (ru) * 2010-02-10 2015-10-20 Иммуникум Аб Улучшенная композиция для ингибирования пролиферации опухолевых клеток
RU2610427C2 (ru) * 2009-07-09 2017-02-10 Тихеникс С.А. Способы и композиции для применения в клеточной терапии
RU2733886C2 (ru) * 2016-06-07 2020-10-07 Куратис Инк. КОМПОЗИЦИЯ ДЛЯ СТИМУЛИРОВАНИЯ СОЗРЕВАНИЯ ДЕНДРИТНЫХ КЛЕТОК, СОДЕРЖАЩАЯ ГИБРИДНЫЙ БЕЛОК Rv2299c/ESAT-6
RU2749610C2 (ru) * 2015-09-15 2021-06-16 Нортвест Байотерапьютикс, Инк. Способы, относящиеся к композициям активированных дендритных клеток и к иммунотерапевтическому лечению индивидуумов с прогрессирующим раком

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WO2005077411A2 (en) * 2004-02-10 2005-08-25 Innate Pharma Composition and method for the treatment of carcinoma
US20060216269A1 (en) * 2004-09-17 2006-09-28 Kenichiro Hasumi Dendritic cell tumor injection (DCTI) therapy
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WO2006095330A2 (en) * 2005-03-10 2006-09-14 Yeda Research And Development Co. Ltd. Methods and immunogenic cell preparations for treating antigen-associated diseases
WO2007001200A1 (en) * 2005-06-23 2007-01-04 Obschestvo S Ogranichennoi Otvetsvennostyu 'rusgen' Mature dendritic cells loaded with tumor polylysates and antitumoral vaccine base thereon
AR060424A1 (es) * 2007-04-11 2008-06-18 Consejo Nac Invest Cient Tec Lineas celulares , composiciones para el tratamiento de melanomas que las comprenden procedimientos para preparar las composiciones y metodos de tratamiento
WO2008133595A1 (en) * 2007-04-26 2008-11-06 Newbiomed Pika Pte Ltd Compositions and methods for stimulating an immune response in-vivo and in-vitro
WO2008151389A1 (en) * 2007-06-15 2008-12-18 Macfarlane Burnet Institute For Medical Research And Public Health Limited Chemically modified macromolecules
EP2072617A1 (en) * 2007-12-12 2009-06-24 Trimed Biotech GmbH Method for producing dendritic cells
RU2361598C1 (ru) * 2008-02-18 2009-07-20 Тихоокеанский Институт Биоорганической Химии Дальневосточного Отделения Российской Академии Наук (Тибох Дво Ран) Средство, индуцирующее созревание дендритных клеток
KR101946785B1 (ko) * 2008-03-27 2019-02-12 아스테리아스 바이오세라퓨틱스, 인크. 영장류 다능성 줄기 세포의 조혈계 세포로의 분화
CN102933228A (zh) * 2010-03-15 2013-02-13 宾夕法尼亚大学董事会 制备和储存活化的、成熟树突细胞的体系和方法
US8961957B2 (en) 2012-06-27 2015-02-24 Hasumi International Research Foundation Therapy and method for intratumorally introducing cytotoxic T lymphocyte and/or NKT cell with anti-TNF and/or anti-IL-10
GB201300049D0 (en) * 2013-01-03 2013-02-20 Transimmune Ag Method for obtaining immuno-stimulatory dendritic cells
KR20160093012A (ko) 2013-11-05 2016-08-05 코그네이트 바이오서비시즈, 인코포레이티드 암 치료를 위한 체크포인트 억제제 및 치료제의 배합물
GB201413665D0 (en) 2014-07-03 2014-09-17 Transimmune Ag And Yale University Method for obtaining globally activated monocytes
CN107849537A (zh) * 2015-06-30 2018-03-27 西北生物治疗药物公司 诱发改善的或增加的抗肿瘤免疫应答的经最佳活化的树突细胞
WO2018160666A1 (en) * 2017-02-28 2018-09-07 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Short-term activated dc1s and methods for their production and use
GB201711379D0 (en) * 2017-07-14 2017-08-30 Univ Cape Town Maturation of dendritic cells
CN109957548B (zh) * 2017-12-26 2022-03-18 上海尚泰生物技术有限公司 一种基因修饰的树突状细胞疫苗
CN116637180A (zh) * 2022-02-15 2023-08-25 沈阳药科大学 萜类化合物在提高其淋巴靶向作用中的应用
GB2624871A (en) * 2022-11-29 2024-06-05 Alv B As Process for preparing a population of dendritic cells and immunotherapy using the same
EP4520334A1 (en) 2023-09-07 2025-03-12 Mnemo Therapeutics Methods and compositions for improving immune response
WO2025052001A1 (en) 2023-09-07 2025-03-13 Mnemo Therapeutics Methods and compositions for improving immune response

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2610427C2 (ru) * 2009-07-09 2017-02-10 Тихеникс С.А. Способы и композиции для применения в клеточной терапии
RU2565542C2 (ru) * 2010-02-10 2015-10-20 Иммуникум Аб Улучшенная композиция для ингибирования пролиферации опухолевых клеток
WO2013147642A1 (ru) * 2012-03-29 2013-10-03 Egorov Oleg Borisovich Способ противоопухолевой иммунотерапии
RU2530523C2 (ru) * 2012-03-29 2014-10-10 Олег Борисович Егоров Способ противоопухолевой иммунотерапии
RU2749610C2 (ru) * 2015-09-15 2021-06-16 Нортвест Байотерапьютикс, Инк. Способы, относящиеся к композициям активированных дендритных клеток и к иммунотерапевтическому лечению индивидуумов с прогрессирующим раком
RU2733886C2 (ru) * 2016-06-07 2020-10-07 Куратис Инк. КОМПОЗИЦИЯ ДЛЯ СТИМУЛИРОВАНИЯ СОЗРЕВАНИЯ ДЕНДРИТНЫХ КЛЕТОК, СОДЕРЖАЩАЯ ГИБРИДНЫЙ БЕЛОК Rv2299c/ESAT-6

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EP1567155A2 (en) 2005-08-31
IL169002A (en) 2015-01-29
US20120251561A1 (en) 2012-10-04
DE60334725D1 (de) 2010-12-09
PT1567155E (pt) 2011-01-28
AU2011200352A1 (en) 2011-02-17
ATE486125T1 (de) 2010-11-15
JP2006510667A (ja) 2006-03-30
HK1082180A1 (en) 2006-06-02
KR20050084189A (ko) 2005-08-26
PL377209A1 (pl) 2006-01-23
WO2004053072A2 (en) 2004-06-24
EP2260861A1 (en) 2010-12-15
JP2011246493A (ja) 2011-12-08
EP1567155B1 (en) 2010-10-27
JP5707284B2 (ja) 2015-04-30
BRPI0317064B1 (pt) 2020-11-03
CA2509058A1 (en) 2004-06-24
CN102600461A (zh) 2012-07-25
CN1738619B (zh) 2012-04-18
EP1567155A4 (en) 2006-12-13
BRPI0317064B8 (pt) 2021-05-25
ES2354944T3 (es) 2011-03-21
CN102600461B (zh) 2017-07-14
BR0317064A (pt) 2005-10-25
KR101144196B1 (ko) 2012-05-21
CN1738619A (zh) 2006-02-22
AU2003293411B2 (en) 2010-10-28
MXPA05006042A (es) 2005-09-21
US20060057120A1 (en) 2006-03-16
JP4859169B2 (ja) 2012-01-25
WO2004053072A3 (en) 2005-06-16
AU2011200352B2 (en) 2013-06-27
DK1567155T3 (da) 2011-02-14
AU2003293411A1 (en) 2004-06-30
RU2005121256A (ru) 2006-02-10

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