CN102600461B - 给予体外部分成熟的树突细胞治疗肿瘤 - Google Patents

给予体外部分成熟的树突细胞治疗肿瘤 Download PDF

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CN102600461B
CN102600461B CN201210027703.4A CN201210027703A CN102600461B CN 102600461 B CN102600461 B CN 102600461B CN 201210027703 A CN201210027703 A CN 201210027703A CN 102600461 B CN102600461 B CN 102600461B
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dendritic cells
cells
composition
tumor
bcg
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CN102600461A (zh
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M·L·博希
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Northwest Biotherapeutics LLC
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
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    • C12N5/0639—Dendritic cells, e.g. Langherhans cells in the epidermis
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/19—Dendritic cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/20—Cellular immunotherapy characterised by the effect or the function of the cells
    • A61K40/24—Antigen-presenting cells [APC]
    • A—HUMAN NECESSITIES
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    • A61K40/00—Cellular immunotherapy
    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41—Vertebrate antigens
    • A61K40/42—Cancer antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
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    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C12N5/12—Fused cells, e.g. hybridomas
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    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
    • A61K2239/31—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterized by the route of administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
    • A61K2239/46—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterised by the cancer treated
    • A61K2239/50—Colon
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/24—Interferons [IFN]

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  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
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CN201210027703.4A 2002-12-06 2003-12-05 给予体外部分成熟的树突细胞治疗肿瘤 Expired - Fee Related CN102600461B (zh)

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US43126702P 2002-12-06 2002-12-06
US60/431,267 2002-12-06
CN2003801089756A CN1738619B (zh) 2002-12-06 2003-12-05 给予体外部分成熟的树突细胞治疗肿瘤的制药用途

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CN102600461B true CN102600461B (zh) 2017-07-14

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CN2003801089756A Expired - Fee Related CN1738619B (zh) 2002-12-06 2003-12-05 给予体外部分成熟的树突细胞治疗肿瘤的制药用途

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US (2) US20060057120A1 (https=)
EP (2) EP2260861A1 (https=)
JP (2) JP4859169B2 (https=)
KR (1) KR101144196B1 (https=)
CN (2) CN102600461B (https=)
AT (1) ATE486125T1 (https=)
AU (2) AU2003293411B2 (https=)
BR (1) BRPI0317064B8 (https=)
CA (1) CA2509058A1 (https=)
DE (1) DE60334725D1 (https=)
DK (1) DK1567155T3 (https=)
ES (1) ES2354944T3 (https=)
IL (1) IL169002A (https=)
MX (1) MXPA05006042A (https=)
PL (1) PL377209A1 (https=)
PT (1) PT1567155E (https=)
RU (1) RU2348418C2 (https=)
WO (1) WO2004053072A2 (https=)

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KR101946785B1 (ko) * 2008-03-27 2019-02-12 아스테리아스 바이오세라퓨틱스, 인크. 영장류 다능성 줄기 세포의 조혈계 세포로의 분화
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RU2530523C2 (ru) * 2012-03-29 2014-10-10 Олег Борисович Егоров Способ противоопухолевой иммунотерапии
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KR20160093012A (ko) 2013-11-05 2016-08-05 코그네이트 바이오서비시즈, 인코포레이티드 암 치료를 위한 체크포인트 억제제 및 치료제의 배합물
GB201413665D0 (en) 2014-07-03 2014-09-17 Transimmune Ag And Yale University Method for obtaining globally activated monocytes
CN107849537A (zh) * 2015-06-30 2018-03-27 西北生物治疗药物公司 诱发改善的或增加的抗肿瘤免疫应答的经最佳活化的树突细胞
JP6980650B2 (ja) 2015-09-15 2021-12-15 ノースウエスト バイオセラピューティクス，インコーポレイティド 進行したがんを有する被験体のための活性化樹状細胞組成物および免疫療法処置に関する方法
KR101749165B1 (ko) * 2016-06-07 2017-06-23 충남대학교산학협력단 Rv2299c 또는 Rv2299c와 ESAT-6 융합한 단백질을 포함하는 수지상 세포의 성숙화 촉진용 조성물
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EP1567155A2 (en) 2005-08-31
IL169002A (en) 2015-01-29
US20120251561A1 (en) 2012-10-04
DE60334725D1 (de) 2010-12-09
PT1567155E (pt) 2011-01-28
RU2348418C2 (ru) 2009-03-10
AU2011200352A1 (en) 2011-02-17
ATE486125T1 (de) 2010-11-15
JP2006510667A (ja) 2006-03-30
HK1082180A1 (en) 2006-06-02
KR20050084189A (ko) 2005-08-26
PL377209A1 (pl) 2006-01-23
WO2004053072A2 (en) 2004-06-24
EP2260861A1 (en) 2010-12-15
JP2011246493A (ja) 2011-12-08
EP1567155B1 (en) 2010-10-27
JP5707284B2 (ja) 2015-04-30
BRPI0317064B1 (pt) 2020-11-03
CA2509058A1 (en) 2004-06-24
CN102600461A (zh) 2012-07-25
CN1738619B (zh) 2012-04-18
EP1567155A4 (en) 2006-12-13
BRPI0317064B8 (pt) 2021-05-25
ES2354944T3 (es) 2011-03-21
BR0317064A (pt) 2005-10-25
KR101144196B1 (ko) 2012-05-21
CN1738619A (zh) 2006-02-22
AU2003293411B2 (en) 2010-10-28
MXPA05006042A (es) 2005-09-21
US20060057120A1 (en) 2006-03-16
JP4859169B2 (ja) 2012-01-25
WO2004053072A3 (en) 2005-06-16
AU2011200352B2 (en) 2013-06-27
DK1567155T3 (da) 2011-02-14
AU2003293411A1 (en) 2004-06-30
RU2005121256A (ru) 2006-02-10

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