RU2216330C2 - Фармацевтическая композиция, содержащая нуклеотидный аналог, и способ ее приготовления - Google Patents
Фармацевтическая композиция, содержащая нуклеотидный аналог, и способ ее приготовления Download PDFInfo
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- RU2216330C2 RU2216330C2 RU2000103216/14A RU2000103216A RU2216330C2 RU 2216330 C2 RU2216330 C2 RU 2216330C2 RU 2000103216/14 A RU2000103216/14 A RU 2000103216/14A RU 2000103216 A RU2000103216 A RU 2000103216A RU 2216330 C2 RU2216330 C2 RU 2216330C2
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/04—Drugs for disorders of the respiratory system for throat disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Pulmonology (AREA)
- Epidemiology (AREA)
- Genetics & Genomics (AREA)
- Urology & Nephrology (AREA)
- Otolaryngology (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Saccharide Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9702680-1 | 1997-07-11 | ||
| SE9702680A SE9702680D0 (sv) | 1997-07-11 | 1997-07-11 | New formulation |
Publications (2)
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| RU2000103216A RU2000103216A (ru) | 2002-01-10 |
| RU2216330C2 true RU2216330C2 (ru) | 2003-11-20 |
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| RU2000103216/14A RU2216330C2 (ru) | 1997-07-11 | 1998-06-29 | Фармацевтическая композиция, содержащая нуклеотидный аналог, и способ ее приготовления |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006038647A1 (ja) * | 2004-10-05 | 2006-04-13 | Asahi Kasei Pharma Corporation | 補酵素の安定化方法およびその組成物 |
| US8759316B2 (en) | 2008-05-13 | 2014-06-24 | The Medicines Company | Maintenance of platelet inhibition during antiplatelet therapy |
| WO2009140092A1 (en) | 2008-05-13 | 2009-11-19 | The Medicines Company | Maintenance of platelet inhibition during antiplatelet therapy |
| US20130303477A1 (en) | 2008-05-13 | 2013-11-14 | The Medicines Company | Maintenance of Platelet Inhibition During Antiplatelet Therapy |
| US9427448B2 (en) | 2009-11-11 | 2016-08-30 | The Medicines Company | Methods of treating, reducing the incidence of, and/or preventing ischemic events |
| US20120141468A1 (en) * | 2008-05-13 | 2012-06-07 | Lisa Ruderman Chen | Maintenance of platelet inhibition during antiplatelet therapy |
| ES2470329T3 (es) | 2009-08-28 | 2014-06-23 | Daiichi Sankyo Company, Limited | Derivado del ácido 3-(biariloxi) priopi�nico |
| ES2773040T3 (es) | 2009-11-11 | 2020-07-09 | Chiesi Farm Spa | Métodos de tratamiento o prevención de trombosis de stent |
| US10376532B2 (en) | 2009-11-11 | 2019-08-13 | Chiesi Farmaceutici, S.P.A. | Methods of treating, reducing the incidence of, and/or preventing ischemic events |
| CN104666315A (zh) * | 2010-12-10 | 2015-06-03 | 西格玛制药实验有限责任公司 | 口服活性核苷酸类似物或口服活性核苷酸类似物前药的高度稳定组合物 |
| BR112013020377B1 (pt) | 2011-02-09 | 2022-06-07 | Chiesi Farmaceutici S.P.A. | Usos de um antagonista do receptor p2y12 reversível na fabricação de um medicamento útil para o tratamento da hipertensão pulmonar |
| DK2744424T3 (en) | 2011-08-17 | 2018-01-22 | Samuel Shiber | Adaptively rotating catheter to open clogged vessels in the body |
| EA034550B1 (ru) | 2013-03-09 | 2020-02-19 | КЬЕЗИ ФАРМАЧЕУТИЧИ С.п.А. | Способы лечения, снижения частоты и/или профилактики ишемических событий |
| CN103772461A (zh) * | 2014-01-06 | 2014-05-07 | 南京正科制药有限公司 | 一种坎格雷洛晶型ⅰ |
| MX391152B (es) | 2015-01-14 | 2025-03-21 | Chiesi Farm Spa | Formulaciones farmaceuticas que comprenden cangrelor de alta pureza y metodos para preparar y utilizar las mismas. |
| BR112019022676A2 (pt) | 2017-06-23 | 2020-05-19 | Chiesi Farm Spa | método de prevenção de trombose de derivação da artéria sistêmica-para-pulmonar |
| TWI857957B (zh) | 2018-06-19 | 2024-10-11 | 德商Ｕｃｂ製藥有限公司 | 吡啶基及吡基-（氮）吲哚磺醯胺 |
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| DE2423811A1 (de) * | 1973-05-17 | 1974-12-05 | Kohjin Co | Verfahren zur herstellung von gefriergetrockneten 2,2'-anhydro-1-beta-d-arabinofuranosylcytosin-praeparaten und injektionspraeparat |
| WO1994018216A1 (en) * | 1993-02-10 | 1994-08-18 | Astra Pharmaceuticals Limited | N-alkyl-2-substituted atp analogues |
| RU99115747A (ru) * | 1996-12-20 | 2001-05-10 | Астра Фармасьютикалз Лтд. | Фармацевтические композиции для сушки вымораживанием |
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| JPS5874966A (ja) * | 1981-10-28 | 1983-05-06 | Mikuni Jukogyo Kk | 高圧往復動機の軸封装置 |
| JPS5874696A (ja) * | 1981-10-30 | 1983-05-06 | 株式会社 ヤトロン | アデノシン三リン酸の安定化方法 |
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| AU3095092A (en) * | 1991-12-09 | 1993-07-19 | Asahi Kasei Kogyo Kabushiki Kaisha | Stabilized parathyroid hormone composition |
| NZ270077A (en) * | 1993-12-14 | 1996-04-26 | Lilly Co Eli | Aqueous complexes of benzothiophenes and cyclodextrins |
| DE4405426A1 (de) * | 1994-02-21 | 1995-08-24 | Boehringer Mannheim Gmbh | Pharmazeutisches Präparat enthaltend Plasminogenaktivator (t-PA) oder dessen Derivate |
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| ID21635A (id) * | 1996-12-20 | 1999-07-08 | Astra Pharma Prod | Komposisi farmasi untuk pengeringan beku |
-
1997
- 1997-07-11 SE SE9702680A patent/SE9702680D0/xx unknown
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1998
- 1998-06-19 TW TW087109890A patent/TW585764B/zh not_active IP Right Cessation
- 1998-06-29 KR KR1020007000205A patent/KR100786654B1/ko not_active Expired - Lifetime
- 1998-06-29 DK DK98934017T patent/DK1000079T3/da active
- 1998-06-29 EP EP98934017A patent/EP1000079B1/en not_active Expired - Lifetime
- 1998-06-29 WO PCT/SE1998/001287 patent/WO1999002542A1/en not_active Ceased
- 1998-06-29 PT PT98934017T patent/PT1000079E/pt unknown
- 1998-06-29 AU AU83625/98A patent/AU8362598A/en not_active Abandoned
- 1998-06-29 CN CN98807089A patent/CN1263533A/zh active Pending
- 1998-06-29 DE DE69836023T patent/DE69836023T2/de not_active Expired - Lifetime
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- 1998-06-29 BR BR9810703-8A patent/BR9810703A/pt not_active Application Discontinuation
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- 1998-06-29 ID IDW20000028A patent/ID24716A/id unknown
- 1998-06-29 CN CNA2006100092846A patent/CN1864696A/zh active Pending
- 1998-06-29 UA UA2000010491A patent/UA65576C2/uk unknown
- 1998-06-29 AT AT98934017T patent/ATE340801T1/de active
- 1998-06-29 US US09/125,165 patent/US6130208A/en not_active Expired - Lifetime
- 1998-06-29 NZ NZ502073A patent/NZ502073A/en not_active IP Right Cessation
- 1998-06-29 RU RU2000103216/14A patent/RU2216330C2/ru active
- 1998-06-29 IL IL13386898A patent/IL133868A0/xx unknown
- 1998-06-29 ES ES98934017T patent/ES2273425T3/es not_active Expired - Lifetime
- 1998-06-30 AR ARP980103182A patent/AR013157A1/es not_active Application Discontinuation
- 1998-07-10 MY MYPI98003170A patent/MY116421A/en unknown
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1999
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2000
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- 2000-01-10 NO NO20000123A patent/NO329918B1/no not_active IP Right Cessation
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2006
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Patent Citations (3)
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| DE2423811A1 (de) * | 1973-05-17 | 1974-12-05 | Kohjin Co | Verfahren zur herstellung von gefriergetrockneten 2,2'-anhydro-1-beta-d-arabinofuranosylcytosin-praeparaten und injektionspraeparat |
| WO1994018216A1 (en) * | 1993-02-10 | 1994-08-18 | Astra Pharmaceuticals Limited | N-alkyl-2-substituted atp analogues |
| RU99115747A (ru) * | 1996-12-20 | 2001-05-10 | Астра Фармасьютикалз Лтд. | Фармацевтические композиции для сушки вымораживанием |
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| Date | Code | Title | Description |
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| RH4A | Copy of patent granted that was duplicated for the russian federation |
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| PC4A | Invention patent assignment |
Effective date: 20070723 |