RU2135502C1 - Диаминовые соли клавулановой кислоты, способ их получения (варианты), способ получения клавулановой кислоты или ее фармацевтически приемлемой соли, способ очистки клавулановой кислоты или ее соли - Google Patents

Диаминовые соли клавулановой кислоты, способ их получения (варианты), способ получения клавулановой кислоты или ее фармацевтически приемлемой соли, способ очистки клавулановой кислоты или ее соли Download PDF

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Publication number
RU2135502C1
RU2135502C1 RU94046014A RU94046014A RU2135502C1 RU 2135502 C1 RU2135502 C1 RU 2135502C1 RU 94046014 A RU94046014 A RU 94046014A RU 94046014 A RU94046014 A RU 94046014A RU 2135502 C1 RU2135502 C1 RU 2135502C1
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RU
Russia
Prior art keywords
clavulanic acid
salt
diamine
pharmaceutically acceptable
synthesis
Prior art date
Application number
RU94046014A
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English (en)
Russian (ru)
Other versions
RU94046014A (ru
Inventor
Гейсберт Вебер Питер
Original Assignee
Гист-Брокейдс Н.В.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Гист-Брокейдс Н.В. filed Critical Гист-Брокейдс Н.В.
Priority claimed from PCT/EP1994/000919 external-priority patent/WO1994022873A1/en
Publication of RU94046014A publication Critical patent/RU94046014A/ru
Application granted granted Critical
Publication of RU2135502C1 publication Critical patent/RU2135502C1/ru

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D503/00—Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D503/10—Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D503/12—Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 unsubstituted in position 6
    • C07D503/14—Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 unsubstituted in position 6 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, other than a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, attached in position 3
    • C07D503/16—Radicals substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical
    • C07D503/18—Radicals substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical by oxygen atoms

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
RU94046014A 1993-03-26 1994-03-22 Диаминовые соли клавулановой кислоты, способ их получения (варианты), способ получения клавулановой кислоты или ее фармацевтически приемлемой соли, способ очистки клавулановой кислоты или ее соли RU2135502C1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP93200872.5 1993-03-26
EP93200872 1993-03-26
PCT/EP1994/000919 WO1994022873A1 (en) 1993-03-26 1994-03-22 Diamine salts of clavulanic acid

Publications (2)

Publication Number Publication Date
RU94046014A RU94046014A (ru) 1996-10-10
RU2135502C1 true RU2135502C1 (ru) 1999-08-27

Family

ID=8213723

Family Applications (1)

Application Number Title Priority Date Filing Date
RU94046014A RU2135502C1 (ru) 1993-03-26 1994-03-22 Диаминовые соли клавулановой кислоты, способ их получения (варианты), способ получения клавулановой кислоты или ее фармацевтически приемлемой соли, способ очистки клавулановой кислоты или ее соли

Country Status (8)

Country Link
JP (1) JP2839955B2 (lv)
KR (1) KR100187333B1 (lv)
BG (1) BG61948B1 (lv)
BR (1) BR9404743A (lv)
GR (2) GR950300030T1 (lv)
LV (1) LV11180B (lv)
RU (1) RU2135502C1 (lv)
SI (1) SI0647229T1 (lv)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1578739A (en) * 1976-07-23 1980-11-05 Beecham Group Ltd Amine salts of clavulanic acid methods for their preparation and compositions containing them
AT399155B (de) * 1992-03-26 1995-03-27 Lek Tovarna Farmacevtskih Neue alkylendiammonium-diclavulanat-derivate, verfahren zu deren herstellung sowie deren verwendung

Also Published As

Publication number Publication date
LV11180B (en) 1996-08-20
BG61948B1 (bg) 1998-10-30
RU94046014A (ru) 1996-10-10
KR950701635A (ko) 1995-04-28
SI0647229T1 (en) 1997-10-31
GR950300030T1 (en) 1995-06-30
GR3021347T3 (en) 1997-01-31
BG99212A (bg) 1995-12-29
BR9404743A (pt) 1999-09-28
LV11180A (lv) 1996-04-20
JPH07507573A (ja) 1995-08-24
JP2839955B2 (ja) 1998-12-24
KR100187333B1 (ko) 1999-05-01

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