RU2019129082A - Фармацевтическая композиция, содержащая электрогидродинамически полученные волокна, композиция, имеющая улучшенное время удержания в месте применения - Google Patents

Фармацевтическая композиция, содержащая электрогидродинамически полученные волокна, композиция, имеющая улучшенное время удержания в месте применения Download PDF

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RU2019129082A
RU2019129082A RU2019129082A RU2019129082A RU2019129082A RU 2019129082 A RU2019129082 A RU 2019129082A RU 2019129082 A RU2019129082 A RU 2019129082A RU 2019129082 A RU2019129082 A RU 2019129082A RU 2019129082 A RU2019129082 A RU 2019129082A
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Russia
Prior art keywords
patch
mucous membrane
patch according
mucosal
hydrophilic
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RU2019129082A
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English (en)
Russian (ru)
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RU2019129082A3 (enExample
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Йенс ХАНСЕН
Мартин Эдуардо Сантосильдес РОМЕРО
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Афикс Терапьютикс А/С
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Publication of RU2019129082A publication Critical patent/RU2019129082A/ru
Publication of RU2019129082A3 publication Critical patent/RU2019129082A3/ru

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0092—Hollow drug-filled fibres, tubes of the core-shell type, coated fibres, coated rods, microtubules or nanotubes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nanotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Spinning Methods And Devices For Manufacturing Artificial Fibers (AREA)
  • Nonwoven Fabrics (AREA)
RU2019129082A 2015-11-19 2016-11-18 Фармацевтическая композиция, содержащая электрогидродинамически полученные волокна, композиция, имеющая улучшенное время удержания в месте применения RU2019129082A (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA201570745 2015-11-19
DKPA201570745 2015-11-19

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
RU2018109496A Division RU2701513C2 (ru) 2015-11-19 2016-11-18 Фармацевтическая композиция, содержащая электрогидродинамически полученные волокна, композиция, имеющая улучшенное время удержания в месте применения

Publications (2)

Publication Number Publication Date
RU2019129082A true RU2019129082A (ru) 2020-04-28
RU2019129082A3 RU2019129082A3 (enExample) 2022-10-19

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Application Number Title Priority Date Filing Date
RU2019129082A RU2019129082A (ru) 2015-11-19 2016-11-18 Фармацевтическая композиция, содержащая электрогидродинамически полученные волокна, композиция, имеющая улучшенное время удержания в месте применения
RU2018109496A RU2701513C2 (ru) 2015-11-19 2016-11-18 Фармацевтическая композиция, содержащая электрогидродинамически полученные волокна, композиция, имеющая улучшенное время удержания в месте применения

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RU2018109496A RU2701513C2 (ru) 2015-11-19 2016-11-18 Фармацевтическая композиция, содержащая электрогидродинамически полученные волокна, композиция, имеющая улучшенное время удержания в месте применения

Country Status (17)

Country Link
US (4) US20180221295A1 (enExample)
EP (1) EP3334412B1 (enExample)
JP (2) JP6606279B2 (enExample)
KR (3) KR102435996B1 (enExample)
CN (1) CN108135833B (enExample)
AU (2) AU2016358266B2 (enExample)
BR (1) BR112018001978A2 (enExample)
CA (1) CA2993377C (enExample)
DK (1) DK3334412T3 (enExample)
ES (1) ES2900741T3 (enExample)
IL (1) IL258093B (enExample)
MX (1) MX391778B (enExample)
MY (1) MY167777A (enExample)
NZ (1) NZ740615A (enExample)
RU (2) RU2019129082A (enExample)
SG (1) SG10201913222XA (enExample)
WO (1) WO2017085264A1 (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3050026A1 (en) 2017-01-23 2018-07-26 Afyx Therapeutics A/S Method for preparing electrospun fibers with a high content of a bioadhesive substance
BR112019014236A2 (pt) 2017-01-23 2020-03-17 Afyx Therapeutics A/S Método para a fabricação de um produto de duas camadas à base de fibras eletrofiadas
WO2021050532A1 (en) * 2019-09-09 2021-03-18 Afyx Therapeutics A/S Compositions for treating fungal infections
CA3157209A1 (en) * 2019-10-08 2021-04-15 Afyx Therapeutics A/S Compositions for the delivery of proteins
EP4121017A4 (en) * 2020-03-17 2024-07-03 Blaesi, Aron H. EXPANDABLE, MULTI-EXCIPIENT STRUCTURED DOSAGE FORM FOR EXTENDED ACTIVE INGREDIENT RELEASE
IL303390A (en) 2020-12-03 2023-08-01 Battelle Memorial Institute Compositions of polymer nanoparticles and DNA nanostructures and methods for non-viral transport
WO2022216977A1 (en) 2021-04-07 2022-10-13 Batelle Memorial Institute Rapid design, build, test, and learn technologies for identifying and using non-viral carriers
EP4108231A1 (en) * 2021-06-25 2022-12-28 Johann-Wolfgang-Goethe-Universität Frankfurt am Main In-situ dissolving electrospun polymer fibers for ocular drug delivery
EP4124336B1 (en) * 2021-07-30 2023-10-25 Cannamedical Pharma GmbH Transmucosal patch comprising a cannabinoid and/or an opioid
WO2023094457A1 (en) 2021-11-23 2023-06-01 Afyx Therapeutics A/S Mucosal patches and methods of use thereof
WO2024160792A1 (en) * 2023-01-30 2024-08-08 Cannamedical Pharma Gmbh Improved transmucosal patch comprising a cannabinoid and/or an opioid
EP4773947A1 (en) 2023-09-06 2026-07-15 Afyx Development A/S Compositions and methods for treating and preventing oral cancer
WO2025072751A1 (en) 2023-09-29 2025-04-03 Battelle Memorial Institute Polymer nanoparticle compositions for in vivo expression of polypeptides
AU2024393766A1 (en) 2023-12-08 2026-06-18 Battelle Memorial Institute Use of dna origami nanostructures for molecular information based data storage systems
KR20250176151A (ko) * 2024-06-11 2025-12-18 주식회사 아이메디텍 중재시술용 지혈 의료용 나노섬유 제조방법 및 이에 의한 의료용 나노섬유

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61280423A (ja) 1985-06-05 1986-12-11 Kiyuukiyuu Yakuhin Kogyo Kk 口腔内粘膜貼付剤
US6753454B1 (en) * 1999-10-08 2004-06-22 The University Of Akron Electrospun fibers and an apparatus therefor
KR100806412B1 (ko) * 2000-01-28 2008-02-21 스미스클라인 비참 코포레이션 전기방사 약제학적 조성물
US7309498B2 (en) * 2001-10-10 2007-12-18 Belenkaya Bronislava G Biodegradable absorbents and methods of preparation
US20030017208A1 (en) * 2002-07-19 2003-01-23 Francis Ignatious Electrospun pharmaceutical compositions
TW200410714A (en) * 2002-08-07 2004-07-01 Smithkline Beecham Corp Electrospun amorphous pharmaceutical compositions
CA2495181A1 (en) * 2002-08-13 2004-02-19 Medtronic, Inc. Active agent delivery system including a hydrophilic polymer, medical device, and method
EP2271301A4 (en) * 2008-03-27 2014-07-02 Agigma Inc METHOD AND COMPOSITIONS FOR THE DELIVERY OF FUNDS
US20130295143A1 (en) * 2012-05-02 2013-11-07 Massachusetts Institute Of Technology Electroprocessing of active pharmaceutical ingredients
CN102670483B (zh) * 2012-05-09 2014-04-02 上海交通大学 一种用于高血脂症治疗的静电纺丝纤维膜制剂及其制备方法
US20150290354A1 (en) * 2012-10-22 2015-10-15 North Carolina State University Nonwoven fiber materials
EP2810645B1 (en) * 2013-06-06 2017-05-24 A. Sezai Sarac New Drug Delivery System
IL291842A (en) * 2014-06-10 2022-06-01 Afyx Therapeutics As Compositions comprising electrohydrodynamically obtained fibres for administration of specific dosages of an active substance to skin or mucosa

Also Published As

Publication number Publication date
US20240139117A1 (en) 2024-05-02
MX2018005206A (es) 2018-08-01
BR112018001978A2 (pt) 2018-09-18
EP3334412B1 (en) 2021-10-20
US20180221295A1 (en) 2018-08-09
SG10201913222XA (en) 2020-03-30
RU2018109496A3 (enExample) 2019-09-19
NZ740615A (en) 2019-06-28
CN108135833A (zh) 2018-06-08
KR20190067280A (ko) 2019-06-14
MX391778B (es) 2025-03-21
ES2900741T3 (es) 2022-03-18
AU2018220020B2 (en) 2020-05-21
US20190254985A1 (en) 2019-08-22
CN108135833B (zh) 2022-11-29
RU2018109496A (ru) 2019-09-19
CA2993377A1 (en) 2017-05-26
AU2016358266A1 (en) 2018-04-05
EP3334412A1 (en) 2018-06-20
MY167777A (en) 2018-09-25
KR20180040704A (ko) 2018-04-20
CA2993377C (en) 2019-11-12
KR20190020173A (ko) 2019-02-27
AU2018220020C1 (en) 2020-09-17
US20230285313A1 (en) 2023-09-14
JP6606279B2 (ja) 2019-11-13
KR102001163B1 (ko) 2019-07-18
IL258093A (en) 2018-05-31
JP2020022787A (ja) 2020-02-13
WO2017085264A1 (en) 2017-05-26
IL258093B (en) 2022-03-01
DK3334412T3 (da) 2022-01-17
JP6929916B2 (ja) 2021-09-01
AU2016358266B2 (en) 2018-06-21
HK1256209A1 (en) 2019-09-13
KR102435996B1 (ko) 2022-08-25
AU2018220020A1 (en) 2018-09-06
JP2018528256A (ja) 2018-09-27
RU2701513C2 (ru) 2019-09-27

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