DK3334412T3 - Farmaceutisk sammensætning, som omfatter elektrohydrodynamisk opnåede fibre, hvilken sammensætning har forøget opholdstid på påføringsstedet - Google Patents

Farmaceutisk sammensætning, som omfatter elektrohydrodynamisk opnåede fibre, hvilken sammensætning har forøget opholdstid på påføringsstedet Download PDF

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Publication number
DK3334412T3
DK3334412T3 DK16797943.4T DK16797943T DK3334412T3 DK 3334412 T3 DK3334412 T3 DK 3334412T3 DK 16797943 T DK16797943 T DK 16797943T DK 3334412 T3 DK3334412 T3 DK 3334412T3
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DK
Denmark
Prior art keywords
electrohydrodynamic
residence
fibers
acquired
increased
Prior art date
Application number
DK16797943.4T
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English (en)
Inventor
Jens Hansen
Martin Eduardo Santocildes Romero
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Afyx Therapeutics As
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Application filed by Afyx Therapeutics As filed Critical Afyx Therapeutics As
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Publication of DK3334412T3 publication Critical patent/DK3334412T3/da

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0092Hollow drug-filled fibres, tubes of the core-shell type, coated fibres, coated rods, microtubules or nanotubes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38Cellulose; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nanotechnology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Dermatology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nonwoven Fabrics (AREA)
  • Spinning Methods And Devices For Manufacturing Artificial Fibers (AREA)
DK16797943.4T 2015-11-19 2016-11-18 Farmaceutisk sammensætning, som omfatter elektrohydrodynamisk opnåede fibre, hvilken sammensætning har forøget opholdstid på påføringsstedet DK3334412T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA201570745 2015-11-19
PCT/EP2016/078151 WO2017085264A1 (en) 2015-11-19 2016-11-18 A pharmaceutical composition comprising electrohydrodynamically obtained fibres, the composition having improved residence time on the application site

Publications (1)

Publication Number Publication Date
DK3334412T3 true DK3334412T3 (da) 2022-01-17

Family

ID=58718438

Family Applications (1)

Application Number Title Priority Date Filing Date
DK16797943.4T DK3334412T3 (da) 2015-11-19 2016-11-18 Farmaceutisk sammensætning, som omfatter elektrohydrodynamisk opnåede fibre, hvilken sammensætning har forøget opholdstid på påføringsstedet

Country Status (18)

Country Link
US (4) US20180221295A1 (da)
EP (1) EP3334412B1 (da)
JP (2) JP6606279B2 (da)
KR (3) KR102001163B1 (da)
CN (1) CN108135833B (da)
AU (2) AU2016358266B2 (da)
BR (1) BR112018001978A2 (da)
CA (1) CA2993377C (da)
DK (1) DK3334412T3 (da)
ES (1) ES2900741T3 (da)
HK (1) HK1256209A1 (da)
IL (1) IL258093B (da)
MX (1) MX2018005206A (da)
MY (1) MY167777A (da)
NZ (1) NZ740615A (da)
RU (2) RU2701513C2 (da)
SG (1) SG10201913222XA (da)
WO (1) WO2017085264A1 (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2019126497A (ru) 2017-01-23 2021-02-24 Афикс Терапьютикс А/С Способ получения электроспряденных волокон с высоким содержанием биоадгезивнго вещества
ES2887977T3 (es) 2017-01-23 2021-12-29 Afyx Therapeutics As Método para la fabricación de un producto de dos capas a base de fibras electrohiladas
WO2021050532A1 (en) * 2019-09-09 2021-03-18 Afyx Therapeutics A/S Compositions for treating fungal infections
CA3157209A1 (en) 2019-10-08 2021-04-15 Afyx Therapeutics A/S Compositions for the delivery of proteins
JP2023517987A (ja) * 2020-03-17 2023-04-27 アーロン エイチ. ブレイジー, 延長された薬物放出のための膨張可能なマルチ賦形剤の構造化された剤形
EP4108231A1 (en) * 2021-06-25 2022-12-28 Johann-Wolfgang-Goethe-Universität Frankfurt am Main In-situ dissolving electrospun polymer fibers for ocular drug delivery
PL4124336T3 (pl) * 2021-07-30 2024-02-26 Cannamedical Pharma Gmbh Plaster przezśluzówkowy obejmujący kannabinoid i/lub opioid
CA3239200A1 (en) 2021-11-23 2023-06-01 Afyx Development A/S Mucosal patches and methods of use thereof

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61280423A (ja) 1985-06-05 1986-12-11 Kiyuukiyuu Yakuhin Kogyo Kk 口腔内粘膜貼付剤
US6753454B1 (en) * 1999-10-08 2004-06-22 The University Of Akron Electrospun fibers and an apparatus therefor
PL356924A1 (en) * 2000-01-28 2004-07-12 Smithkline Beecham Corporation Electrospun pharmaceutical compositions
US7309498B2 (en) * 2001-10-10 2007-12-18 Belenkaya Bronislava G Biodegradable absorbents and methods of preparation
US20030017208A1 (en) * 2002-07-19 2003-01-23 Francis Ignatious Electrospun pharmaceutical compositions
TW200410714A (en) * 2002-08-07 2004-07-01 Smithkline Beecham Corp Electrospun amorphous pharmaceutical compositions
WO2004014448A1 (en) * 2002-08-13 2004-02-19 Medtronic, Inc. Active agent delivery system including a hydrophilic polymer, medical device, and method
US9233080B2 (en) * 2008-03-27 2016-01-12 Agigma, Inc. Compositions and methods for the delivery of agents
US20130295143A1 (en) * 2012-05-02 2013-11-07 Massachusetts Institute Of Technology Electroprocessing of active pharmaceutical ingredients
CN102670483B (zh) * 2012-05-09 2014-04-02 上海交通大学 一种用于高血脂症治疗的静电纺丝纤维膜制剂及其制备方法
WO2014066297A1 (en) * 2012-10-22 2014-05-01 North Carolina State University Nonwoven fiber materials
EP2810645B1 (en) * 2013-06-06 2017-05-24 A. Sezai Sarac New Drug Delivery System
US10052291B2 (en) * 2014-06-10 2018-08-21 Dermtreat Aps Compositions comprising electrohydrodynamically obtained fibres for administration of specific doses of an active substance to skin or mucosa

Also Published As

Publication number Publication date
AU2016358266A1 (en) 2018-04-05
US20230285313A1 (en) 2023-09-14
AU2018220020C1 (en) 2020-09-17
MX2018005206A (es) 2018-08-01
IL258093A (en) 2018-05-31
EP3334412A1 (en) 2018-06-20
HK1256209A1 (zh) 2019-09-13
JP2020022787A (ja) 2020-02-13
EP3334412B1 (en) 2021-10-20
BR112018001978A2 (pt) 2018-09-18
CN108135833B (zh) 2022-11-29
CA2993377C (en) 2019-11-12
WO2017085264A1 (en) 2017-05-26
AU2018220020B2 (en) 2020-05-21
AU2016358266B2 (en) 2018-06-21
CA2993377A1 (en) 2017-05-26
KR102001163B1 (ko) 2019-07-18
JP6606279B2 (ja) 2019-11-13
IL258093B (en) 2022-03-01
CN108135833A (zh) 2018-06-08
JP2018528256A (ja) 2018-09-27
RU2701513C2 (ru) 2019-09-27
ES2900741T3 (es) 2022-03-18
RU2018109496A (ru) 2019-09-19
KR20180040704A (ko) 2018-04-20
KR102435996B1 (ko) 2022-08-25
JP6929916B2 (ja) 2021-09-01
MY167777A (en) 2018-09-25
US20240139117A1 (en) 2024-05-02
AU2018220020A1 (en) 2018-09-06
US20190254985A1 (en) 2019-08-22
NZ740615A (en) 2019-06-28
RU2018109496A3 (da) 2019-09-19
US20180221295A1 (en) 2018-08-09
KR20190067280A (ko) 2019-06-14
RU2019129082A (ru) 2020-04-28
SG10201913222XA (en) 2020-03-30
KR20190020173A (ko) 2019-02-27

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