SG10201913222XA - A pharmaceutical composition comprising electrohydrodynamically obtained fibres, the composition having improved residence time on the application site - Google Patents

A pharmaceutical composition comprising electrohydrodynamically obtained fibres, the composition having improved residence time on the application site

Info

Publication number
SG10201913222XA
SG10201913222XA SG10201913222XA SG10201913222XA SG10201913222XA SG 10201913222X A SG10201913222X A SG 10201913222XA SG 10201913222X A SG10201913222X A SG 10201913222XA SG 10201913222X A SG10201913222X A SG 10201913222XA SG 10201913222X A SG10201913222X A SG 10201913222XA
Authority
SG
Singapore
Prior art keywords
composition
residence time
application site
pharmaceutical composition
improved residence
Prior art date
Application number
SG10201913222XA
Inventor
Jens Hansen
Martin Eduardo Santocildes Romero
Original Assignee
Afyx Therapeutics As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Afyx Therapeutics As filed Critical Afyx Therapeutics As
Publication of SG10201913222XA publication Critical patent/SG10201913222XA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0092Hollow drug-filled fibres, tubes of the core-shell type, coated fibres, coated rods, microtubules or nanotubes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38Cellulose; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
SG10201913222XA 2015-11-19 2016-11-18 A pharmaceutical composition comprising electrohydrodynamically obtained fibres, the composition having improved residence time on the application site SG10201913222XA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DKPA201570745 2015-11-19

Publications (1)

Publication Number Publication Date
SG10201913222XA true SG10201913222XA (en) 2020-03-30

Family

ID=58718438

Family Applications (1)

Application Number Title Priority Date Filing Date
SG10201913222XA SG10201913222XA (en) 2015-11-19 2016-11-18 A pharmaceutical composition comprising electrohydrodynamically obtained fibres, the composition having improved residence time on the application site

Country Status (18)

Country Link
US (3) US20180221295A1 (en)
EP (1) EP3334412B1 (en)
JP (2) JP6606279B2 (en)
KR (3) KR102435996B1 (en)
CN (1) CN108135833B (en)
AU (2) AU2016358266B2 (en)
BR (1) BR112018001978A2 (en)
CA (1) CA2993377C (en)
DK (1) DK3334412T3 (en)
ES (1) ES2900741T3 (en)
HK (1) HK1256209A1 (en)
IL (1) IL258093B (en)
MX (1) MX2018005206A (en)
MY (1) MY167777A (en)
NZ (1) NZ740615A (en)
RU (2) RU2019129082A (en)
SG (1) SG10201913222XA (en)
WO (1) WO2017085264A1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7162014B2 (en) 2017-01-23 2022-10-27 アフリックス セラピューティクス アー/エス Method for fabricating two-layer products based on electrospun fibers
JP7353980B2 (en) 2017-01-23 2023-10-02 アフリックス セラピューティクス アー/エス Method for preparing electrospun fibers with high content of bioadhesives
WO2021050532A1 (en) * 2019-09-09 2021-03-18 Afyx Therapeutics A/S Compositions for treating fungal infections
US20240074970A1 (en) 2019-10-08 2024-03-07 Afyx Therapeutics A/S Compositions for the delivery of proteins
EP4108231A1 (en) * 2021-06-25 2022-12-28 Johann-Wolfgang-Goethe-Universität Frankfurt am Main In-situ dissolving electrospun polymer fibers for ocular drug delivery
EP4124336B1 (en) * 2021-07-30 2023-10-25 Cannamedical Pharma GmbH Transmucosal patch comprising a cannabinoid and/or an opioid
WO2023094457A1 (en) 2021-11-23 2023-06-01 Afyx Therapeutics A/S Mucosal patches and methods of use thereof

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61280423A (en) 1985-06-05 1986-12-11 Kiyuukiyuu Yakuhin Kogyo Kk Mucosal application agent in oral cavity
US6753454B1 (en) * 1999-10-08 2004-06-22 The University Of Akron Electrospun fibers and an apparatus therefor
WO2001054667A1 (en) * 2000-01-28 2001-08-02 Smithkline Beecham Corporation Electrospun pharmaceutical compositions
US7309498B2 (en) * 2001-10-10 2007-12-18 Belenkaya Bronislava G Biodegradable absorbents and methods of preparation
US20030017208A1 (en) * 2002-07-19 2003-01-23 Francis Ignatious Electrospun pharmaceutical compositions
TW200410714A (en) * 2002-08-07 2004-07-01 Smithkline Beecham Corp Electrospun amorphous pharmaceutical compositions
EP1530489A1 (en) * 2002-08-13 2005-05-18 Medtronic, Inc. Active agent delivery system including a hydrophilic polymer, medical device, and method
EP2271301A4 (en) * 2008-03-27 2014-07-02 Agigma Inc Methods and compositions for the delivery of agents
WO2013165604A1 (en) * 2012-05-02 2013-11-07 Massachusetts Institute Of Technology Electroprocessing of active pharmaceutical ingredients
CN102670483B (en) * 2012-05-09 2014-04-02 上海交通大学 Electrostatic spinning fiber membrane preparation for treating hyperlipidemia and preparation method thereof
WO2014066297A1 (en) * 2012-10-22 2014-05-01 North Carolina State University Nonwoven fiber materials
EP2810645B1 (en) * 2013-06-06 2017-05-24 A. Sezai Sarac New Drug Delivery System
NZ727975A (en) * 2014-06-10 2019-01-25 Dermtreat Aps Compositions comprising electrohydrodynamically obtained fibres for administration of specific dosages of an active substance to skin or mucosa

Also Published As

Publication number Publication date
AU2016358266A1 (en) 2018-04-05
JP2020022787A (en) 2020-02-13
US20190254985A1 (en) 2019-08-22
EP3334412A1 (en) 2018-06-20
BR112018001978A2 (en) 2018-09-18
EP3334412B1 (en) 2021-10-20
KR20190020173A (en) 2019-02-27
HK1256209A1 (en) 2019-09-13
KR20190067280A (en) 2019-06-14
KR20180040704A (en) 2018-04-20
NZ740615A (en) 2019-06-28
JP6929916B2 (en) 2021-09-01
AU2018220020C1 (en) 2020-09-17
KR102001163B1 (en) 2019-07-18
CA2993377C (en) 2019-11-12
AU2016358266B2 (en) 2018-06-21
RU2018109496A (en) 2019-09-19
RU2019129082A (en) 2020-04-28
MY167777A (en) 2018-09-25
ES2900741T3 (en) 2022-03-18
RU2701513C2 (en) 2019-09-27
CN108135833A (en) 2018-06-08
IL258093A (en) 2018-05-31
DK3334412T3 (en) 2022-01-17
US20230285313A1 (en) 2023-09-14
IL258093B (en) 2022-03-01
AU2018220020A1 (en) 2018-09-06
US20180221295A1 (en) 2018-08-09
WO2017085264A1 (en) 2017-05-26
AU2018220020B2 (en) 2020-05-21
JP2018528256A (en) 2018-09-27
RU2018109496A3 (en) 2019-09-19
CN108135833B (en) 2022-11-29
KR102435996B1 (en) 2022-08-25
CA2993377A1 (en) 2017-05-26
MX2018005206A (en) 2018-08-01
JP6606279B2 (en) 2019-11-13

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