RU2016129186A - Композиция, содержащая пробиотические бактерии, для применения в лечении иммунных расстройств - Google Patents
Композиция, содержащая пробиотические бактерии, для применения в лечении иммунных расстройств Download PDFInfo
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- RU2016129186A RU2016129186A RU2016129186A RU2016129186A RU2016129186A RU 2016129186 A RU2016129186 A RU 2016129186A RU 2016129186 A RU2016129186 A RU 2016129186A RU 2016129186 A RU2016129186 A RU 2016129186A RU 2016129186 A RU2016129186 A RU 2016129186A
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- 239000000203 mixture Substances 0.000 title claims 17
- 241000894006 Bacteria Species 0.000 title claims 5
- 239000006041 probiotic Substances 0.000 title claims 3
- 230000000529 probiotic effect Effects 0.000 title claims 3
- 235000018291 probiotics Nutrition 0.000 title claims 3
- 208000026278 immune system disease Diseases 0.000 title 1
- 206010012438 Dermatitis atopic Diseases 0.000 claims 10
- 201000008937 atopic dermatitis Diseases 0.000 claims 10
- 241000186869 Lactobacillus salivarius Species 0.000 claims 6
- 230000000069 prophylactic effect Effects 0.000 claims 6
- 230000001225 therapeutic effect Effects 0.000 claims 6
- 208000010668 atopic eczema Diseases 0.000 claims 4
- 241000186012 Bifidobacterium breve Species 0.000 claims 3
- 206010003645 Atopy Diseases 0.000 claims 2
- 208000004262 Food Hypersensitivity Diseases 0.000 claims 2
- 206010016946 Food allergy Diseases 0.000 claims 2
- RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical class OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 claims 2
- 206010020751 Hypersensitivity Diseases 0.000 claims 2
- 206010061598 Immunodeficiency Diseases 0.000 claims 2
- 208000029462 Immunodeficiency disease Diseases 0.000 claims 2
- 206010039085 Rhinitis allergic Diseases 0.000 claims 2
- 201000010105 allergic rhinitis Diseases 0.000 claims 2
- 230000007815 allergy Effects 0.000 claims 2
- 208000006673 asthma Diseases 0.000 claims 2
- 230000001580 bacterial effect Effects 0.000 claims 2
- 235000020299 breve Nutrition 0.000 claims 2
- 238000004113 cell culture Methods 0.000 claims 2
- 208000024711 extrinsic asthma Diseases 0.000 claims 2
- 230000007813 immunodeficiency Effects 0.000 claims 2
- 244000005700 microbiome Species 0.000 claims 2
- 230000007170 pathology Effects 0.000 claims 2
- 229920002907 Guar gum Polymers 0.000 claims 1
- 229920001202 Inulin Polymers 0.000 claims 1
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- 239000000284 extract Substances 0.000 claims 1
- 235000013305 food Nutrition 0.000 claims 1
- 229960002154 guar gum Drugs 0.000 claims 1
- 235000010417 guar gum Nutrition 0.000 claims 1
- 239000000665 guar gum Substances 0.000 claims 1
- JYJIGFIDKWBXDU-MNNPPOADSA-N inulin Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)OC[C@]1(OC[C@]2(OC[C@]3(OC[C@]4(OC[C@]5(OC[C@]6(OC[C@]7(OC[C@]8(OC[C@]9(OC[C@]%10(OC[C@]%11(OC[C@]%12(OC[C@]%13(OC[C@]%14(OC[C@]%15(OC[C@]%16(OC[C@]%17(OC[C@]%18(OC[C@]%19(OC[C@]%20(OC[C@]%21(OC[C@]%22(OC[C@]%23(OC[C@]%24(OC[C@]%25(OC[C@]%26(OC[C@]%27(OC[C@]%28(OC[C@]%29(OC[C@]%30(OC[C@]%31(OC[C@]%32(OC[C@]%33(OC[C@]%34(OC[C@]%35(OC[C@]%36(O[C@@H]%37[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O%37)O)[C@H]([C@H](O)[C@@H](CO)O%36)O)[C@H]([C@H](O)[C@@H](CO)O%35)O)[C@H]([C@H](O)[C@@H](CO)O%34)O)[C@H]([C@H](O)[C@@H](CO)O%33)O)[C@H]([C@H](O)[C@@H](CO)O%32)O)[C@H]([C@H](O)[C@@H](CO)O%31)O)[C@H]([C@H](O)[C@@H](CO)O%30)O)[C@H]([C@H](O)[C@@H](CO)O%29)O)[C@H]([C@H](O)[C@@H](CO)O%28)O)[C@H]([C@H](O)[C@@H](CO)O%27)O)[C@H]([C@H](O)[C@@H](CO)O%26)O)[C@H]([C@H](O)[C@@H](CO)O%25)O)[C@H]([C@H](O)[C@@H](CO)O%24)O)[C@H]([C@H](O)[C@@H](CO)O%23)O)[C@H]([C@H](O)[C@@H](CO)O%22)O)[C@H]([C@H](O)[C@@H](CO)O%21)O)[C@H]([C@H](O)[C@@H](CO)O%20)O)[C@H]([C@H](O)[C@@H](CO)O%19)O)[C@H]([C@H](O)[C@@H](CO)O%18)O)[C@H]([C@H](O)[C@@H](CO)O%17)O)[C@H]([C@H](O)[C@@H](CO)O%16)O)[C@H]([C@H](O)[C@@H](CO)O%15)O)[C@H]([C@H](O)[C@@H](CO)O%14)O)[C@H]([C@H](O)[C@@H](CO)O%13)O)[C@H]([C@H](O)[C@@H](CO)O%12)O)[C@H]([C@H](O)[C@@H](CO)O%11)O)[C@H]([C@H](O)[C@@H](CO)O%10)O)[C@H]([C@H](O)[C@@H](CO)O9)O)[C@H]([C@H](O)[C@@H](CO)O8)O)[C@H]([C@H](O)[C@@H](CO)O7)O)[C@H]([C@H](O)[C@@H](CO)O6)O)[C@H]([C@H](O)[C@@H](CO)O5)O)[C@H]([C@H](O)[C@@H](CO)O4)O)[C@H]([C@H](O)[C@@H](CO)O3)O)[C@H]([C@H](O)[C@@H](CO)O2)O)[C@@H](O)[C@H](O)[C@@H](CO)O1 JYJIGFIDKWBXDU-MNNPPOADSA-N 0.000 claims 1
- 229940029339 inulin Drugs 0.000 claims 1
- 239000006166 lysate Substances 0.000 claims 1
- 239000002417 nutraceutical Substances 0.000 claims 1
- 235000021436 nutraceutical agent Nutrition 0.000 claims 1
- 235000013406 prebiotics Nutrition 0.000 claims 1
- 239000007787 solid Substances 0.000 claims 1
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- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
- A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
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- A23L33/135—Bacteria or derivatives thereof, e.g. probiotics
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- A—HUMAN NECESSITIES
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- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
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- Food Science & Technology (AREA)
- Otolaryngology (AREA)
- Dermatology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Plant Substances (AREA)
Claims (16)
1. Композиция, содержащая две культуры пробиотических бактерий, Lactobacillus salivarius (LS01) DSM 22775, депонированную 23.07.2009 в немецкой коллекции микроорганизмов и клеточных культур (Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSMZ)), и Bifidobacterium breve (BR03) DSM 16604, депонированную 20.07.2004 в немецкой коллекции микроорганизмов и клеточных культур GmbH-DSMZ,
для применения в профилактическом и/или терапевтическом лечении патологий, выбранных из группы, состоящей из аллергий, атопии, аллергического ринита, пищевой гиперчувствительности, атопического дерматита, экземы, астмы или иммунодефицитов.
2. Композиция по п. 1 для применения в профилактическом и/или терапевтическом лечении атопического дерматита и/или экземы.
3. Композиция по п. 1 для применения в профилактическом и/или терапевтическом лечении атопического дерматита.
4. Композиция для применения по п. 1, состоящая из Lactobacillus salivarius (LS01) DSM 22775, Bifidobacterium breve (BR03) DSM 16604 и L pentosus (LPS01) DSM 21980.
5. Композиция для применения по п. 1, где указанные бактериальные культуры представлены в указанных композициях в форме живых бактерий, мертвых бактерий или клеточных компонентов, клеточных экстрактов или их лизатов.
6. Композиция для применения по п. 1 в твердой форме для перорального введения.
7. Композиция для применения по п. 1, где указанные культуры пробиотических бактерий присутствуют в концентрации, составляющей от 1×107 до 1×1011 КОЕ (колониеобразующая единица)/г композиции, предпочтительно от 1×108 до 1×1010 КОЕ/г композиции.
8. Композиция для применения по п. 1, дополнительно содержащая диетические волокна с пребиотической активностью, выбранные из фруктоолигосахаридов (FOS), инулина и частично гидролизованной гуаровой камеди (PHGG).
9. Композиция для применения по п. 1, представляющая собой фармацевтическую, диетическую, пищевую или нутрицевтическую композицию.
10. Применение композиции, содержащей следующие культуры бактерий, депонированные в Deutsche Sammlung und Mikroorganismen und Zellkulturen GmbH (DSMZ):
- Lactobacillus salivarius (LS01) DSM 22775, депонированный 23.07.2009;
- Bifidobacterium breve (BR03) DSM 16604, депонированный 20.07.2004;
в профилактическом и/или терапевтическом лечении патологий, выбранных из группы, включающей аллергии, атопию, аллергический ринит, пищевую гиперчувствительность, атопический дерматит, экзему, астму или иммунодефициты.
11. Применение по п. 10, где указанная композиция предназначена для профилактического и/или терапевтического лечения атопического дерматита и/или экземы.
12. Применение по п. 10, где указанная композиция предназначена для профилактического и/или терапевтического лечения атопического дерматита.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITMI2010A000375A IT1398553B1 (it) | 2010-03-08 | 2010-03-08 | Composizione comprendente batteri probiotici per il trattamento di patologie associate con le alterazioni del sistema immunitario. |
| ITMI2010A000375 | 2010-03-08 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2012140052/15A Division RU2605293C2 (ru) | 2010-03-08 | 2011-03-07 | Композиция, содержащая пробиотические бактерии, для применения в лечении иммунных расстройств |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| RU2016129186A true RU2016129186A (ru) | 2018-12-10 |
| RU2016129186A3 RU2016129186A3 (ru) | 2019-11-21 |
| RU2712751C2 RU2712751C2 (ru) | 2020-01-31 |
| RU2712751C9 RU2712751C9 (ru) | 2020-04-28 |
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ID=42942117
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2012140052/15A RU2605293C2 (ru) | 2010-03-08 | 2011-03-07 | Композиция, содержащая пробиотические бактерии, для применения в лечении иммунных расстройств |
| RU2016129186A RU2712751C9 (ru) | 2010-03-08 | 2011-03-07 | Композиция, содержащая пробиотические бактерии, для применения в лечении иммунных расстройств |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2012140052/15A RU2605293C2 (ru) | 2010-03-08 | 2011-03-07 | Композиция, содержащая пробиотические бактерии, для применения в лечении иммунных расстройств |
Country Status (18)
| Country | Link |
|---|---|
| US (3) | US8734783B2 (ru) |
| EP (2) | EP2626076B1 (ru) |
| JP (2) | JP5931754B2 (ru) |
| KR (1) | KR101872946B1 (ru) |
| CN (2) | CN103037876B (ru) |
| AU (1) | AU2011225798B2 (ru) |
| BR (1) | BR112012022755B1 (ru) |
| CA (1) | CA2792343C (ru) |
| DK (2) | DK2626076T3 (ru) |
| ES (2) | ES2581803T3 (ru) |
| HU (2) | HUE030888T2 (ru) |
| IT (1) | IT1398553B1 (ru) |
| PL (2) | PL2626076T3 (ru) |
| PT (2) | PT2626076T (ru) |
| RU (2) | RU2605293C2 (ru) |
| UA (1) | UA111715C2 (ru) |
| WO (1) | WO2011110918A1 (ru) |
| ZA (2) | ZA201207377B (ru) |
Families Citing this family (69)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1398553B1 (it) | 2010-03-08 | 2013-03-01 | Probiotical Spa | Composizione comprendente batteri probiotici per il trattamento di patologie associate con le alterazioni del sistema immunitario. |
| WO2011149335A1 (en) * | 2010-05-25 | 2011-12-01 | N.V. Nutricia | Immune imprinting nutritional composition |
| IT1403661B1 (it) | 2011-01-28 | 2013-10-31 | Probiotical Spa | Composizione effervescente in forma solida per uso in applicazioni vaginali per il trattamento di infezioni vaginali. |
| ITMI20110792A1 (it) | 2011-05-09 | 2012-11-10 | Probiotical Spa | Ceppi di batteri appartenenti al genere bifidobacterium per uso nel trattamento della ipercolesterolemia. |
| ITMI20110793A1 (it) | 2011-05-09 | 2012-11-10 | Probiotical Spa | Ceppi di batteri probiotici e composizione sinbiotica contenente gli stessi destinata alla alimentazione dei neonati. |
| ITMI20110791A1 (it) | 2011-05-09 | 2012-11-10 | Probiotical Spa | Ceppi di batteri in grado di metabolizzare gli ossalati. |
| GB201112091D0 (en) | 2011-07-14 | 2011-08-31 | Gt Biolog Ltd | Bacterial strains isolated from pigs |
| ITRM20110477A1 (it) | 2011-09-09 | 2013-03-10 | Giovanni Mogna | Composizione comprendente n-acetilcisteina e/o lisozima microincapsulato gastroprotetto in associazione con batteri probiotici in grado di ripristinare l'effetto barriera proprio dello stomaco che viene perso durante il trattamento farmacologico dell |
| ITMI20111718A1 (it) | 2011-09-23 | 2013-03-24 | Probiotical Spa | Un materiale impermeabile alla umidita e allo ossigeno per confezionare prodotti dietetici, cosmetici e specialita medicinali. |
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