RU2010142003A - Синбиотическая смесь - Google Patents
Синбиотическая смесь Download PDFInfo
- Publication number
- RU2010142003A RU2010142003A RU2010142003/10A RU2010142003A RU2010142003A RU 2010142003 A RU2010142003 A RU 2010142003A RU 2010142003/10 A RU2010142003/10 A RU 2010142003/10A RU 2010142003 A RU2010142003 A RU 2010142003A RU 2010142003 A RU2010142003 A RU 2010142003A
- Authority
- RU
- Russia
- Prior art keywords
- drug
- nutritional composition
- lactobacillus
- lactosamine
- acetyl
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title claims abstract 13
- 235000019722 synbiotics Nutrition 0.000 title 1
- 239000003814 drug Substances 0.000 claims abstract 14
- 229940079593 drug Drugs 0.000 claims abstract 14
- 235000016709 nutrition Nutrition 0.000 claims abstract 10
- KFEUJDWYNGMDBV-UHFFFAOYSA-N (N-Acetyl)-glucosamin-4-beta-galaktosid Natural products OC1C(NC(=O)C)C(O)OC(CO)C1OC1C(O)C(O)C(O)C(CO)O1 KFEUJDWYNGMDBV-UHFFFAOYSA-N 0.000 claims abstract 6
- KFEUJDWYNGMDBV-LODBTCKLSA-N N-acetyllactosamine Chemical compound O[C@@H]1[C@@H](NC(=O)C)[C@H](O)O[C@H](CO)[C@H]1O[C@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1 KFEUJDWYNGMDBV-LODBTCKLSA-N 0.000 claims abstract 6
- HESSGHHCXGBPAJ-UHFFFAOYSA-N N-acetyllactosamine Natural products CC(=O)NC(C=O)C(O)C(C(O)CO)OC1OC(CO)C(O)C(O)C1O HESSGHHCXGBPAJ-UHFFFAOYSA-N 0.000 claims abstract 6
- 208000015181 infectious disease Diseases 0.000 claims abstract 6
- 241000186604 Lactobacillus reuteri Species 0.000 claims abstract 4
- 229940001882 lactobacillus reuteri Drugs 0.000 claims abstract 4
- 238000004519 manufacturing process Methods 0.000 claims abstract 4
- 229920001542 oligosaccharide Polymers 0.000 claims abstract 4
- 150000002482 oligosaccharides Chemical class 0.000 claims abstract 4
- 230000001717 pathogenic effect Effects 0.000 claims abstract 4
- 230000002265 prevention Effects 0.000 claims abstract 4
- 239000006041 probiotic Substances 0.000 claims abstract 4
- 230000000529 probiotic effect Effects 0.000 claims abstract 4
- 235000018291 probiotics Nutrition 0.000 claims abstract 4
- 241000218588 Lactobacillus rhamnosus Species 0.000 claims abstract 2
- 241000917009 Lactobacillus rhamnosus GG Species 0.000 claims abstract 2
- 241000186610 Lactobacillus sp. Species 0.000 claims abstract 2
- -1 N-acetyl-lactosamine Chemical class 0.000 claims abstract 2
- AXQLFFDZXPOFPO-UHFFFAOYSA-N UNPD216 Natural products O1C(CO)C(O)C(OC2C(C(O)C(O)C(CO)O2)O)C(NC(=O)C)C1OC(C1O)C(O)C(CO)OC1OC1C(O)C(O)C(O)OC1CO AXQLFFDZXPOFPO-UHFFFAOYSA-N 0.000 claims abstract 2
- 244000052616 bacterial pathogen Species 0.000 claims abstract 2
- AXQLFFDZXPOFPO-UNTPKZLMSA-N beta-D-Galp-(1->3)-beta-D-GlcpNAc-(1->3)-beta-D-Galp-(1->4)-beta-D-Glcp Chemical compound O([C@@H]1O[C@H](CO)[C@H](O)[C@@H]([C@H]1O)O[C@H]1[C@@H]([C@H]([C@H](O)[C@@H](CO)O1)O[C@H]1[C@@H]([C@@H](O)[C@@H](O)[C@@H](CO)O1)O)NC(=O)C)[C@H]1[C@H](O)[C@@H](O)[C@H](O)O[C@@H]1CO AXQLFFDZXPOFPO-UNTPKZLMSA-N 0.000 claims abstract 2
- 210000001035 gastrointestinal tract Anatomy 0.000 claims abstract 2
- IEQCXFNWPAHHQR-UHFFFAOYSA-N lacto-N-neotetraose Natural products OCC1OC(OC2C(C(OC3C(OC(O)C(O)C3O)CO)OC(CO)C2O)O)C(NC(=O)C)C(O)C1OC1OC(CO)C(O)C(O)C1O IEQCXFNWPAHHQR-UHFFFAOYSA-N 0.000 claims abstract 2
- USIPEGYTBGEPJN-UHFFFAOYSA-N lacto-N-tetraose Natural products O1C(CO)C(O)C(OC2C(C(O)C(O)C(CO)O2)O)C(NC(=O)C)C1OC1C(O)C(CO)OC(OC(C(O)CO)C(O)C(O)C=O)C1O USIPEGYTBGEPJN-UHFFFAOYSA-N 0.000 claims abstract 2
- 229940062780 lacto-n-neotetraose Drugs 0.000 claims abstract 2
- 229940035901 lactobacillus sp Drugs 0.000 claims abstract 2
- RBMYDHMFFAVMMM-PLQWBNBWSA-N neolactotetraose Chemical compound O([C@H]1[C@H](O)[C@H]([C@@H](O[C@@H]1CO)O[C@@H]1[C@H]([C@H](O[C@H]([C@H](O)CO)[C@H](O)[C@@H](O)C=O)O[C@H](CO)[C@@H]1O)O)NC(=O)C)[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O RBMYDHMFFAVMMM-PLQWBNBWSA-N 0.000 claims abstract 2
- 210000002345 respiratory system Anatomy 0.000 claims abstract 2
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
- A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/135—Bacteria or derivatives thereof, e.g. probiotics
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/20—Reducing nutritive value; Dietetic products with reduced nutritive value
- A23L33/21—Addition of substantially indigestible substances, e.g. dietary fibres
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/40—Complete food formulations for specific consumer groups or specific purposes, e.g. infant formula
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7016—Disaccharides, e.g. lactose, lactulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/702—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2400/00—Lactic or propionic acid bacteria
- A23V2400/11—Lactobacillus
- A23V2400/175—Rhamnosus
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Mycology (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Nutrition Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pediatric Medicine (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Ophthalmology & Optometry (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
1. Препарат, содержащий N-ацетил-лактозамин и/или олигосахарид, включающий N-ацетил-лактозамин, и пробиотический Lactobacillus sp. ! 2. Препарат по п.1, в котором олигосахарид, содержащий N-ацетил-лактозамин, представляет собой лакто-N-тетраозу или лакто-N неотетраозу. ! 3. Препарат по п.1 или 2, в котором пробиотический Lactobacillus sp представляет собой Lactobacillus rhamnosus ATCC 53103, Lactobacillus rhamnosus CGMCC 1.3724, Lactobacillus reuteri ATCC 55730 или Lactobacillus reuteri DSM 17938. ! 4. Питательная композиция, содержащая препарат по любому предшествующему пункту. ! 5. Питательная композиция по п.4, которая представляет собой смесь для младенцев. ! 6. Питательная композиция по п.4 или 5, которая содержит от 0,3 до 4 мас.% препарата по любому из пп.1-3 в расчете на сухую массу. ! 7. Применение препарата по любому из пп.1-3 в производстве питательной композиции или лекарственного средства для предотвращения или лечения патогенных инфекций желудочно-кишечного тракта. ! 8. Применение препарата по любому из пп.1-3 в производстве питательной композиции или лекарственного средства для предотвращения или лечения патогенных инфекций верхних дыхательных путей. ! 9. Применение по п.7 или 8, когда инфекцию вызывают болезнетворные бактерии.
Claims (9)
1. Препарат, содержащий N-ацетил-лактозамин и/или олигосахарид, включающий N-ацетил-лактозамин, и пробиотический Lactobacillus sp.
2. Препарат по п.1, в котором олигосахарид, содержащий N-ацетил-лактозамин, представляет собой лакто-N-тетраозу или лакто-N неотетраозу.
3. Препарат по п.1 или 2, в котором пробиотический Lactobacillus sp представляет собой Lactobacillus rhamnosus ATCC 53103, Lactobacillus rhamnosus CGMCC 1.3724, Lactobacillus reuteri ATCC 55730 или Lactobacillus reuteri DSM 17938.
4. Питательная композиция, содержащая препарат по любому предшествующему пункту.
5. Питательная композиция по п.4, которая представляет собой смесь для младенцев.
6. Питательная композиция по п.4 или 5, которая содержит от 0,3 до 4 мас.% препарата по любому из пп.1-3 в расчете на сухую массу.
7. Применение препарата по любому из пп.1-3 в производстве питательной композиции или лекарственного средства для предотвращения или лечения патогенных инфекций желудочно-кишечного тракта.
8. Применение препарата по любому из пп.1-3 в производстве питательной композиции или лекарственного средства для предотвращения или лечения патогенных инфекций верхних дыхательных путей.
9. Применение по п.7 или 8, когда инфекцию вызывают болезнетворные бактерии.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP08152765 | 2008-03-14 | ||
| EP08152765.7 | 2008-03-14 | ||
| PCT/EP2009/052166 WO2009112361A2 (en) | 2008-03-14 | 2009-02-24 | Synbiotic mixture |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2010142003A true RU2010142003A (ru) | 2012-04-20 |
| RU2495927C2 RU2495927C2 (ru) | 2013-10-20 |
Family
ID=39780479
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2010142003/10A RU2495927C2 (ru) | 2008-03-14 | 2009-02-24 | Синбиотическая смесь |
Country Status (15)
| Country | Link |
|---|---|
| US (3) | US8961953B2 (ru) |
| EP (1) | EP2265135B1 (ru) |
| CN (1) | CN102006788A (ru) |
| AU (1) | AU2009224814B2 (ru) |
| BR (1) | BRPI0909289A2 (ru) |
| CA (1) | CA2718222A1 (ru) |
| ES (1) | ES2658837T3 (ru) |
| MX (1) | MX2010009978A (ru) |
| MY (1) | MY169947A (ru) |
| PT (1) | PT2265135T (ru) |
| RU (1) | RU2495927C2 (ru) |
| SG (1) | SG188887A1 (ru) |
| UA (1) | UA100551C2 (ru) |
| WO (1) | WO2009112361A2 (ru) |
| ZA (1) | ZA201007327B (ru) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101460181A (zh) * | 2006-06-13 | 2009-06-17 | 雀巢产品技术援助有限公司 | 用非致病性菌株预防和治疗中耳炎 |
| CN101273736B (zh) * | 2007-03-28 | 2012-08-08 | 北京弗蒙特生物技术有限公司 | 一种在常温下保持高活菌数的发酵乳的制备方法 |
| US8498729B2 (en) | 2008-08-29 | 2013-07-30 | Smp Logic Systems Llc | Manufacturing execution system for use in manufacturing baby formula |
| AU2011209407B2 (en) * | 2010-01-28 | 2014-02-27 | Ab-Biotics S.A. | Probiotic composition for use in the treatment of bowel inflammation |
| BR112013015951A2 (pt) | 2010-12-31 | 2018-07-10 | Abbott Lab | composições nutricionais compreendendo oligossacarídeos e nucleotídeos de leite humano e usos destas para tratar e/ou prevenir infecção viral entérica. |
| BR112013016903A2 (pt) * | 2010-12-31 | 2019-09-24 | Abbott Lab | oligossacarídeos de leite humano para modular inflamação |
| CN103369974A (zh) | 2010-12-31 | 2013-10-23 | 雅培制药有限公司 | 包含人乳低聚糖和长链多不饱和脂肪酸的营养型制剂以及其用途 |
| MY166946A (en) | 2010-12-31 | 2018-07-25 | Abbott Lab | Methods of using human milk oligosaccharides for improving airway respiratory health |
| JP5331156B2 (ja) | 2011-04-28 | 2013-10-30 | シャープ株式会社 | 投光ユニットおよび投光装置 |
| MX352677B (es) | 2011-06-20 | 2017-12-04 | Heinz Co Brands H J Llc | Composiciones probioticas y metodos. |
| PL2768313T3 (pl) * | 2011-10-18 | 2016-02-29 | Nestec Sa | Kompozycja do stosowania dla zwiększania absorpcji magnezu oraz/albo retencji magnezu w organizmie |
| KR101381794B1 (ko) * | 2012-04-10 | 2014-04-07 | 씨제이제일제당 (주) | 타가토스 및 프로바이오틱 유산균을 함유하는 신바이오틱 식품 조성물 |
| EP2928325A1 (en) * | 2012-12-10 | 2015-10-14 | N.V. Nutricia | Nutritional composition with non digestible oligosaccharides |
| MX2016005961A (es) | 2013-11-15 | 2016-12-16 | Nestec Sa | Composiciones para usar en la prevencion o tratamiento de infecciones del trs en infantes o niños jovenes en riesgo. |
| WO2015140299A1 (en) | 2014-03-20 | 2015-09-24 | Universiteit Antwerpen | Oronasopharyngeal probiotics |
| AU2016227595B2 (en) | 2015-03-05 | 2020-08-27 | Société des Produits Nestlé S.A. | Compositions for use in the prevention or treatment of otitis or bronchitis in infants or young children |
| MX378680B (es) | 2015-03-05 | 2025-03-11 | Soc Des Produits Nestle S A Star | Composiciones para usar en la prevencion o el tratamiento de infecciones/inflamaciones gastrointestinales en infantes o niños pequeños. |
| RU2019105567A (ru) | 2016-07-28 | 2020-08-28 | Фонтерра Ко-Оперэйтив Груп Лимитед | Молочный продукт и способ |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4839281A (en) | 1985-04-17 | 1989-06-13 | New England Medical Center Hospitals, Inc. | Lactobacillus strains and methods of selection |
| EP0481038B1 (en) | 1990-04-16 | 2002-10-02 | The Trustees Of The University Of Pennsylvania | Saccharide compositions, methods and apparatus for their synthesis |
| ATE172245T1 (de) | 1992-07-06 | 1998-10-15 | Nestle Sa | Milchbakterien |
| EP0577903B1 (fr) | 1992-07-06 | 1997-12-17 | Societe Des Produits Nestle S.A. | Agent antigastrite |
| FI104465B (fi) | 1995-06-14 | 2000-02-15 | Valio Oy | Proteiinihydrolysaatteja allergioiden hoitamiseksi tai estämiseksi, niiden valmistus ja käyttö |
| US6045854A (en) * | 1997-03-31 | 2000-04-04 | Abbott Laboraties | Nutritional formulations containing oligosaccharides |
| EP1034787A1 (en) | 1999-03-11 | 2000-09-13 | Société des Produits Nestlé S.A. | Lactobacillus strains preventing diarrhea caused by pathogenic bacteria |
| AUPQ275799A0 (en) | 1999-09-10 | 1999-10-07 | Luminis Pty Limited | Recombinant bacterium expressing an oligosaccharide receptor mimic |
| AU2002352531A1 (en) * | 2001-06-29 | 2003-03-03 | Carbion Oy | Use of at least one glycoinhibitor substance |
| JP5219329B2 (ja) * | 2002-06-28 | 2013-06-26 | ネステク、リミテッド | 下痢の予防又は治療用の医薬組成物 |
| GB0308104D0 (en) * | 2003-04-08 | 2003-05-14 | Novartis Nutrition Ag | Organic compounds |
| EP1732395B1 (en) * | 2004-03-19 | 2015-07-29 | DuPont Nutrition Biosciences ApS | Emulsified probiotic product |
| PT1629850E (pt) * | 2004-08-24 | 2007-08-14 | Nutricia Nv | Composição nutricional que compreende a administração de oligossacarídeos indigeríveis |
| EP1776877A1 (en) * | 2005-10-21 | 2007-04-25 | N.V. Nutricia | Method for stimulating the intestinal flora |
| CA2644968A1 (en) * | 2006-03-07 | 2007-09-13 | Nestec S.A. | Synbiotic mixture |
| BRPI0708701A2 (pt) * | 2006-03-10 | 2011-06-07 | Nutricia Nv | uso de um sacarìdeo não digerìvel solúvel em água |
| US7374924B2 (en) * | 2006-06-05 | 2008-05-20 | Biogaia Ab | Use of selected lactic acid bacteria for reducing infantile colic |
| EP2060257A1 (en) | 2007-11-08 | 2009-05-20 | Nestec S.A. | Prevention and treatment of secondary infections following viral infection |
| WO2009060257A2 (en) | 2007-11-09 | 2009-05-14 | Acco Uk Limited | Staple remover |
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2009
- 2009-02-24 MX MX2010009978A patent/MX2010009978A/es active IP Right Grant
- 2009-02-24 US US12/922,377 patent/US8961953B2/en active Active
- 2009-02-24 MY MYPI2010004274A patent/MY169947A/en unknown
- 2009-02-24 ES ES09719188.6T patent/ES2658837T3/es active Active
- 2009-02-24 UA UAA201012139A patent/UA100551C2/ru unknown
- 2009-02-24 RU RU2010142003/10A patent/RU2495927C2/ru active
- 2009-02-24 WO PCT/EP2009/052166 patent/WO2009112361A2/en not_active Ceased
- 2009-02-24 CA CA2718222A patent/CA2718222A1/en not_active Abandoned
- 2009-02-24 SG SG2013018049A patent/SG188887A1/en unknown
- 2009-02-24 EP EP09719188.6A patent/EP2265135B1/en active Active
- 2009-02-24 CN CN2009801129835A patent/CN102006788A/zh active Pending
- 2009-02-24 BR BRPI0909289-7A patent/BRPI0909289A2/pt active Search and Examination
- 2009-02-24 PT PT97191886T patent/PT2265135T/pt unknown
- 2009-02-24 AU AU2009224814A patent/AU2009224814B2/en active Active
-
2010
- 2010-10-13 ZA ZA2010/07327A patent/ZA201007327B/en unknown
-
2013
- 2013-08-09 US US13/963,581 patent/US9254303B2/en active Active
-
2015
- 2015-12-22 US US14/978,064 patent/US9943556B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US9943556B2 (en) | 2018-04-17 |
| MX2010009978A (es) | 2010-11-30 |
| US20160106788A1 (en) | 2016-04-21 |
| MY169947A (en) | 2019-06-19 |
| AU2009224814A1 (en) | 2009-09-17 |
| ZA201007327B (en) | 2018-11-28 |
| PT2265135T (pt) | 2018-02-21 |
| WO2009112361A3 (en) | 2009-11-05 |
| SG188887A1 (en) | 2013-04-30 |
| CN102006788A (zh) | 2011-04-06 |
| AU2009224814B2 (en) | 2015-02-05 |
| EP2265135B1 (en) | 2017-12-20 |
| US20110020304A1 (en) | 2011-01-27 |
| US20130323216A1 (en) | 2013-12-05 |
| US9254303B2 (en) | 2016-02-09 |
| RU2495927C2 (ru) | 2013-10-20 |
| US8961953B2 (en) | 2015-02-24 |
| UA100551C2 (en) | 2013-01-10 |
| CA2718222A1 (en) | 2009-09-17 |
| BRPI0909289A2 (pt) | 2015-08-04 |
| EP2265135A2 (en) | 2010-12-29 |
| WO2009112361A2 (en) | 2009-09-17 |
| ES2658837T3 (es) | 2018-03-12 |
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