EA201390305A1 - Композиции для влагалищного и перорального введения lactobacillus и их применение - Google Patents

Композиции для влагалищного и перорального введения lactobacillus и их применение

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Publication number
EA201390305A1
EA201390305A1 EA201390305A EA201390305A EA201390305A1 EA 201390305 A1 EA201390305 A1 EA 201390305A1 EA 201390305 A EA201390305 A EA 201390305A EA 201390305 A EA201390305 A EA 201390305A EA 201390305 A1 EA201390305 A1 EA 201390305A1
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EA
Eurasian Patent Office
Prior art keywords
compositions
lactic acid
moistural
lactobacillus
acid bacteria
Prior art date
Application number
EA201390305A
Other languages
English (en)
Other versions
EA024951B1 (ru
Inventor
Герберт Кисс
Конрад Й. Домиг
Вольфганг Кнайфель
Хельмут Фирнштайн
Франк М. Унгер
Original Assignee
ЭйчЭсОу ХЕЛТ КЕА ГМБХ
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43798526&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA201390305(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by ЭйчЭсОу ХЕЛТ КЕА ГМБХ filed Critical ЭйчЭсОу ХЕЛТ КЕА ГМБХ
Publication of EA201390305A1 publication Critical patent/EA201390305A1/ru
Publication of EA024951B1 publication Critical patent/EA024951B1/ru

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
    • A23C9/00—Milk preparations; Milk powder or milk powder preparations
    • A23C9/12—Fermented milk preparations; Treatment using microorganisms or enzymes
    • A23C9/123—Fermented milk preparations; Treatment using microorganisms or enzymes using only microorganisms of the genus lactobacteriaceae; Yoghurt
    • A23C9/1234—Fermented milk preparations; Treatment using microorganisms or enzymes using only microorganisms of the genus lactobacteriaceae; Yoghurt characterised by using a Lactobacillus sp. other than Lactobacillus Bulgaricus, including Bificlobacterium sp.
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/38—Other non-alcoholic beverages
    • A23L2/382—Other non-alcoholic beverages fermented
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/135—Bacteria or derivatives thereof, e.g. probiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2400/00—Lactic or propionic acid bacteria
    • A23V2400/11—Lactobacillus
    • A23V2400/145—Gasseri
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2400/00—Lactic or propionic acid bacteria
    • A23V2400/11—Lactobacillus
    • A23V2400/149—Jensenii
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2400/00—Lactic or propionic acid bacteria
    • A23V2400/11—Lactobacillus
    • A23V2400/175—Rhamnosus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/225—Lactobacillus

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Epidemiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Nutrition Science (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Endocrinology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Настоящее изобретение относится к композициям молочно-кислых бактерий (Lactobacilli) человека для перорального и влагалищного введения и к их применению для физиологического восстановления флоры влагалища, физиологического поддержания флоры молочно-кислых бактерий при патологическом дефиците для продуцирования молочно-кислых бактерий, для лечения бессимптомного бактериального вагиноза и предупреждения преждевременных родов, вызванных бактериальным вагинозом.
EA201390305A 2010-09-14 2011-09-13 Композиции для влагалищного и перорального введения lactobacillus и их применение EA024951B1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP10176578A EP2428214A1 (en) 2010-09-14 2010-09-14 Compositions for the vaginal and oral administration of lactobacillus and uses thereof
US41296410P 2010-11-12 2010-11-12
PCT/EP2011/065877 WO2012035028A1 (en) 2010-09-14 2011-09-13 Compositions for the vaginal and oral administration of lactobacillus and uses thereof

Publications (2)

Publication Number Publication Date
EA201390305A1 true EA201390305A1 (ru) 2013-09-30
EA024951B1 EA024951B1 (ru) 2016-11-30

Family

ID=43798526

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201390305A EA024951B1 (ru) 2010-09-14 2011-09-13 Композиции для влагалищного и перорального введения lactobacillus и их применение

Country Status (6)

Country Link
US (1) US8846027B2 (ru)
EP (2) EP2428214A1 (ru)
CA (1) CA2809398C (ru)
EA (1) EA024951B1 (ru)
UA (1) UA115520C2 (ru)
WO (1) WO2012035028A1 (ru)

Families Citing this family (29)

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Publication number Priority date Publication date Assignee Title
FR2992973B1 (fr) * 2012-07-09 2015-12-18 S P M D Nouvelle souche de lactobacillus crispatus
FR2992861B1 (fr) * 2012-07-09 2014-10-17 Probionov Utilisation de thiosulfate pour potentialiser l'effet anti-pathogene des lactobacilles
FR3018193B1 (fr) * 2014-03-10 2017-09-08 Probionov Comprime vaginal muco-adhesif a liberation prolongee
WO2015173693A1 (en) * 2014-05-16 2015-11-19 Pizeta Group Srl Compositions containing boric acid and a mixture of lactobacillus
CZ2014565A3 (cs) 2014-08-22 2016-03-02 Vysoká škola chemicko - technologická v Praze Kmeny laktobacilů produkující látky účinné proti vaginálním patogenům, jejich použití a hygienické prostředky je obsahující
RU2572351C1 (ru) * 2015-03-03 2016-01-10 Вячеслав Михайлович Абрамов ШТАММ БАКТЕРИЙ Lactobacillus jensenii, ОБЛАДАЮЩИЙ ШИРОКИМ СПЕКТРОМ АНТАГОНИСТИЧЕСКОЙ АКТИВНОСТИ И ПРОБИОТИЧЕСКИЙ КОНСОРЦИУМ ЛАКТОБАКТЕРИЙ ДЛЯ ИЗГОТОВЛЕНИЯ БАКТЕРИАЛЬНЫХ ПРЕПАРАТОВ
WO2016167489A1 (ko) * 2015-04-16 2016-10-20 주식회사 고바이오랩 질 내 병원성 미생물에 대한 증식억제활성을 갖는 락토바실러스 속 균주
US10588926B2 (en) 2015-06-29 2020-03-17 Ferring B.V. Lactobacillus rhamnosus bacterium for treatment of e.g. bacterial vaginosis
CN104998152A (zh) * 2015-07-17 2015-10-28 青岛华仁技术孵化器有限公司 用于治疗慢性尿路感染的中药
US11260086B2 (en) 2016-07-11 2022-03-01 The Brigham And Women's Hospital, Inc. Medicinal vaginal lactobacillus cocktail
WO2018115361A1 (en) * 2016-12-21 2018-06-28 Agriculture And Food Development Authority (Teagasc) Human lactobacilli strains
GB201708932D0 (en) * 2017-06-05 2017-07-19 Probi Ab Microbial compositions
DE102017113263A1 (de) * 2017-06-16 2018-12-20 Lactopia GmbH Pharmazeutische Zusammensetzung enthaltend Bakterienstämme aus der Familie der Lactobacillaceae und Molke
EP3427745A1 (en) 2017-07-12 2019-01-16 Nederlandse Organisatie voor toegepast- natuurwetenschappelijk onderzoek TNO New probiotic composition for prevention of bacterial vaginosis
WO2020007780A1 (en) * 2018-07-02 2020-01-09 Artpred B.V. Method and kit for altering the outcome of an assisted reproductive technology procedure
CN111088178B (zh) * 2018-10-23 2022-11-22 上海上药信谊药厂有限公司 一种产乳酸和h2o2的乳杆菌及其应用
CN110656060B (zh) * 2019-08-09 2020-08-07 四川厌氧生物科技有限责任公司 多联乳杆菌组合物及其在女性阴道健康中的应用
US11037655B2 (en) 2019-10-16 2021-06-15 University Of Maryland, Baltimore Microbiome-based informed method to formulate live biotherapeutics
US10967012B2 (en) 2019-10-16 2021-04-06 University Of Maryland, Baltimore Microbiome-based informed method to formulate live biotherapeutics
EP4108249A4 (en) * 2020-02-17 2024-02-07 Acebiome Inc COMPOSITION FOR THE TREATMENT OF CLIMATE DISORDERS COMPRISING LACTOBACILLUS GASSERI BNR17
IT202000004663A1 (it) * 2020-03-05 2021-09-05 Marca Antonio La Nuovo uso di probiotici
EP4157298A1 (en) * 2020-06-01 2023-04-05 Ferring B.V. Vaginal microbiota compositions
KR102207512B1 (ko) * 2020-06-08 2021-01-27 (주)성운파마코피아 항균 활성을 갖는 락토바실러스 젠세니 swpm104
US20230241135A1 (en) * 2020-06-16 2023-08-03 Kira HALAK A composition for reducing the risk of urinary tract infection and vaginal infection in women
IT202000016666A1 (it) * 2020-07-09 2022-01-09 Uriach Italy S R L Nuovo ceppo della specie lacticaseibacillus rhamnosus, sue composizioni e loro uso nel trattamento di infezioni genitourinarie
AU2021417032A1 (en) * 2021-01-05 2023-07-27 Lactobio A/S Strains, compositions and methods of use
CN112342175B (zh) * 2021-01-09 2021-05-04 南京北极光生物科技有限公司 一种阴道健康益生菌组合物及其应用
CA3208572A1 (en) * 2021-02-19 2022-08-25 Phillip Bennett Lactobacillus crispatus composition for use in pregnant subjects
CN113862188B (zh) * 2021-10-15 2023-06-16 广东一元兰欣生物科技有限公司 一株格氏乳杆菌ls03及其应用

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BR9916062A (pt) 1998-12-11 2002-09-24 Urex Biotech Inc Administração oral de lactobacillus para o tratamento e prevenção de infecção urogenital
SE528382C2 (sv) * 2004-10-05 2006-10-31 Probi Ab Probiotiska lactobacillusstammar för förbättrad vaginal hälsa

Also Published As

Publication number Publication date
EP2509610A1 (en) 2012-10-17
US20130171253A1 (en) 2013-07-04
UA115520C2 (uk) 2017-11-27
CA2809398A1 (en) 2012-03-22
US8846027B2 (en) 2014-09-30
CA2809398C (en) 2018-04-10
EP2428214A1 (en) 2012-03-14
EA024951B1 (ru) 2016-11-30
EP2509610B1 (en) 2013-03-27
WO2012035028A1 (en) 2012-03-22

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