RU2013114313A - Противокариесные композиции и пробиотики/пребиотики - Google Patents
Противокариесные композиции и пробиотики/пребиотики Download PDFInfo
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- RU2013114313A RU2013114313A RU2013114313/10A RU2013114313A RU2013114313A RU 2013114313 A RU2013114313 A RU 2013114313A RU 2013114313/10 A RU2013114313/10 A RU 2013114313/10A RU 2013114313 A RU2013114313 A RU 2013114313A RU 2013114313 A RU2013114313 A RU 2013114313A
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- 239000006041 probiotic Substances 0.000 title claims abstract 5
- 235000018291 probiotics Nutrition 0.000 title claims abstract 5
- 239000000203 mixture Substances 0.000 title claims 6
- 235000013406 prebiotics Nutrition 0.000 title claims 4
- 230000000675 anti-caries Effects 0.000 title 1
- 239000004599 antimicrobial Substances 0.000 claims abstract 16
- 230000000845 anti-microbial effect Effects 0.000 claims abstract 14
- 230000001580 bacterial effect Effects 0.000 claims abstract 10
- 210000000214 mouth Anatomy 0.000 claims abstract 9
- 208000035473 Communicable disease Diseases 0.000 claims abstract 6
- 235000013376 functional food Nutrition 0.000 claims abstract 5
- 239000003814 drug Substances 0.000 claims abstract 4
- 230000000529 probiotic effect Effects 0.000 claims abstract 4
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims abstract 2
- 108091028043 Nucleic acid sequence Proteins 0.000 claims abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
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Abstract
1. Поддающийся культивированию противомикробный бактериальный штамм, который выбирают из любого из следующих штаммов: СЕСТ 7746, СЕСТ 7747, СЕСТ 7773 и СЕСТ 7775.2. Поддающийся культивированию противомикробный бактериальный штамм, который выбирают из любого из следующих штаммов: СЕСТ 7746, СЕСТ 7747, СЕСТ 7773 и СЕСТ 7775 или их комбинации, для применения в качестве лекарственного средства.3. Поддающийся культивированию противомикробный бактериальный штамм, который выбирают из любого из следующих штаммов: СЕСТ 7746, СЕСТ 7747, СЕСТ 7773 и СЕСТ 7775 или их комбинации, для применения в качестве противомикробного средства.4. Поддающийся культивированию противомикробный бактериальный штамм, который выбирают из любого из следующих штаммов: СЕСТ 7746, СЕСТ 7747, СЕСТ 7773 и СЕСТ 7775 или их комбинации, для применения при лечении инфекционных заболеваний ротовой полости.5. Поддающийся культивированию противомикробный бактериальный штамм, который выбирают из любого из следующих штаммов: СЕСТ 7746, СЕСТ 7747, СЕСТ 7773 и СЕСТ 7775 или их комбинации, для применения в качестве пробиотика или функционального пищевого продукта, разработанного для улучшения состояния здоровья ротовой полости.6. Противомикробное соединение, которое включает последовательности SEQ ID NO: 8 или SEQ ID NO: 9, или Противомикробное соединение, кодируемое последовательностью ДНК, включающей любую из следующих последовательностей: SEQ ID NO: I, SEQ ID NO: 6, SEQ ID NO: 7, SEQ ID NO: 13, SEQ ID NO: 14, SEQ ID NO: 2, SEQ ID NO: 3, SEQ ID NO: 4, SEQ ID NO: 5.7. Противомикробное соединение по п.6, или их комбинации, для применения в качестве лекарственного средства.8. Противомикробное соединение по п.6, или их комбинации, для применения в качестве противоми�
Claims (16)
1. Поддающийся культивированию противомикробный бактериальный штамм, который выбирают из любого из следующих штаммов: СЕСТ 7746, СЕСТ 7747, СЕСТ 7773 и СЕСТ 7775.
2. Поддающийся культивированию противомикробный бактериальный штамм, который выбирают из любого из следующих штаммов: СЕСТ 7746, СЕСТ 7747, СЕСТ 7773 и СЕСТ 7775 или их комбинации, для применения в качестве лекарственного средства.
3. Поддающийся культивированию противомикробный бактериальный штамм, который выбирают из любого из следующих штаммов: СЕСТ 7746, СЕСТ 7747, СЕСТ 7773 и СЕСТ 7775 или их комбинации, для применения в качестве противомикробного средства.
4. Поддающийся культивированию противомикробный бактериальный штамм, который выбирают из любого из следующих штаммов: СЕСТ 7746, СЕСТ 7747, СЕСТ 7773 и СЕСТ 7775 или их комбинации, для применения при лечении инфекционных заболеваний ротовой полости.
5. Поддающийся культивированию противомикробный бактериальный штамм, который выбирают из любого из следующих штаммов: СЕСТ 7746, СЕСТ 7747, СЕСТ 7773 и СЕСТ 7775 или их комбинации, для применения в качестве пробиотика или функционального пищевого продукта, разработанного для улучшения состояния здоровья ротовой полости.
6. Противомикробное соединение, которое включает последовательности SEQ ID NO: 8 или SEQ ID NO: 9, или Противомикробное соединение, кодируемое последовательностью ДНК, включающей любую из следующих последовательностей: SEQ ID NO: I, SEQ ID NO: 6, SEQ ID NO: 7, SEQ ID NO: 13, SEQ ID NO: 14, SEQ ID NO: 2, SEQ ID NO: 3, SEQ ID NO: 4, SEQ ID NO: 5.
7. Противомикробное соединение по п.6, или их комбинации, для применения в качестве лекарственного средства.
8. Противомикробное соединение по п.6, или их комбинации, для применения в качестве противомикробной композиции.
9. Противомикробное соединение по п.6, или их комбинации, для применения в качестве пребиотика или функционального пищевого продукта, разработанного для улучшения состояния здоровья ротовой полости.
10. Противомикробное соединение по п.6, или их комбинации, для применения при лечении инфекционных заболеваний ротовой полости.
11. Пробиотическая/пребиотическая композиция или функциональный пищевой продукт, который включает, по меньшей мере, один противомикробный штамм по любому из пп.1-5, и/или, по меньшей мере, одно противомикробное соединение по любому из пп.6-10.
12. Медико-фармацевтическая композиция, которая включает, по меньшей мере, один противомикробный штамм по любому из пп.1-5, и/или, по меньшей мере, одно противомикробное соединение из пп.6-10.
13. Композиция для поддержания ротовой полости в здоровом состоянии, которая включает, по меньшей мере, один противомикробный штамм по любому из пп.1-5 и/или, по меньшей мере, одно Противомикробное соединение из пп.6-10.
14. Пробиотическая/пребиотическая композиция или функциональный пищевой продукт по п.11 для применения при лечении инфекционных заболеваний ротовой полости.
15. Медико-фармацевтическая композиция по п.12 для применения при лечении инфекционных заболеваний ротовой полости.
16. Композиция для поддержания ротовой полости в здоровом состоянии по п.13 для применения при лечении инфекционных заболеваний ротовой полости.
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US10206959B2 (en) | 2013-02-14 | 2019-02-19 | University Of Florida Research Foundation, Inc. | Probiotic arginolytic oral compositions and methods of making and using probiotic arginolytic oral compositions |
CN105007911A (zh) | 2013-02-14 | 2015-10-28 | 佛罗里达大学研究基金会公司 | 益生精氨酸分解口服组合物以及制备和使用益生精氨酸分解口服组合物的方法 |
CA3006059A1 (en) * | 2015-09-09 | 2017-03-16 | uBiome, Inc. | Method and system for microbiome-derived diagnostics and therapeutics for oral health |
CN105193859A (zh) * | 2015-09-25 | 2015-12-30 | 南昌大学 | 一种天然口腔细菌移植在口腔疾病治疗中的应用 |
CN105193857A (zh) * | 2015-09-25 | 2015-12-30 | 南昌大学 | 一种人工培养口腔细菌移植在口腔疾病治疗中的应用 |
EP3196318A1 (en) | 2016-01-19 | 2017-07-26 | Symrise AG | Probiotics for altering the composition of oral biofilms |
US11230694B2 (en) | 2016-11-24 | 2022-01-25 | Servizo Galego De Saúde (Sergas) | Antimicrobial strain |
EP3351259A1 (en) | 2017-01-18 | 2018-07-25 | Symrise AG | Probiotics for aggregation with disease-associated species in the oral cavity |
US10733214B2 (en) | 2017-03-20 | 2020-08-04 | International Business Machines Corporation | Analyzing metagenomics data |
CN107460150B (zh) * | 2017-09-18 | 2020-03-24 | 沈阳医学院 | Dentisani链球菌及其应用和应用其的产品 |
CN107557317B (zh) * | 2017-09-20 | 2020-03-24 | 沈阳医学院 | 缓症链球菌及其应用和应用其的产品 |
IL293620A (en) * | 2019-12-06 | 2022-08-01 | Forsyth Dental Infirmary For Children | Methods and preparations for the prevention and treatment of tooth decay |
CN112011627B (zh) * | 2020-09-27 | 2022-02-25 | 赤峰家育种猪生态科技集团有限公司 | 与加系大白猪背膘厚相关的分子标记及筛选方法和应用 |
CN114317783B (zh) * | 2021-12-08 | 2023-07-28 | 上海锐翌医学检验实验室有限公司 | 龋齿标志微生物及其应用 |
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CA1321962C (en) | 1985-03-20 | 1993-09-07 | Aizo Matsushiro | Dental caries preventive preparations and method for preparing said preparations |
US5607672A (en) * | 1995-06-07 | 1997-03-04 | University Of Florida Research Foundation, Inc. | Replacement therapy for dental caries |
KR100266752B1 (ko) * | 1997-08-07 | 2001-03-02 | 오종석 | 인체 구강내 치태형성을 억제하는 신규한 유산균 |
US20030077814A1 (en) * | 1997-08-07 | 2003-04-24 | Oh Jong Suk | Novel lactic acid bacteria |
JP2002000261A (ja) * | 2000-06-28 | 2002-01-08 | Ozeki Corp | 防菌剤 |
US7226590B2 (en) * | 2002-02-22 | 2007-06-05 | Blis Technologies Limited | Antimicrobial composition |
JP4181806B2 (ja) | 2002-07-10 | 2008-11-19 | シャープ株式会社 | 印刷版、印刷機および印刷方法ならびに液晶機器の製造装置および製造方法 |
US20060258596A1 (en) * | 2003-02-14 | 2006-11-16 | Walsh Timothy R | Antimicrobial agents |
CA2535764C (en) | 2003-08-11 | 2012-01-24 | Oragenics, Inc. | Compositions and methods for the maintenance of oral health |
EP1634948A1 (en) * | 2004-09-10 | 2006-03-15 | Basf Aktiengesellschaft | Means and methods for preventing and/or treating caries |
AU2007204037B2 (en) * | 2006-01-04 | 2013-01-10 | Annica Almstahl | Probiotic oral health promoting product |
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IL224767A (en) | 2017-02-28 |
EP2612904B1 (en) | 2016-09-21 |
PL2612904T3 (pl) | 2017-07-31 |
JP2013543374A (ja) | 2013-12-05 |
US9629883B2 (en) | 2017-04-25 |
CA2808793A1 (en) | 2012-03-08 |
BR112013004702A2 (pt) | 2018-09-04 |
AU2011298235A1 (en) | 2013-04-18 |
CA2808793C (en) | 2020-09-22 |
KR20140001832A (ko) | 2014-01-07 |
MX2013002247A (es) | 2013-07-03 |
KR101739802B1 (ko) | 2017-05-25 |
AU2011298235B2 (en) | 2016-07-21 |
US20140147426A1 (en) | 2014-05-29 |
RU2650866C2 (ru) | 2018-04-17 |
EP2612904A2 (en) | 2013-07-10 |
MX343566B (es) | 2016-11-09 |
CN103119153B (zh) | 2016-03-23 |
CN103119153A (zh) | 2013-05-22 |
WO2012028759A2 (es) | 2012-03-08 |
ES2608577T3 (es) | 2017-04-12 |
JP5921546B2 (ja) | 2016-05-24 |
WO2012028759A3 (es) | 2012-08-02 |
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