RU2012114854A - Способы лечения псориаза - Google Patents
Способы лечения псориаза Download PDFInfo
- Publication number
- RU2012114854A RU2012114854A RU2012114854/15A RU2012114854A RU2012114854A RU 2012114854 A RU2012114854 A RU 2012114854A RU 2012114854/15 A RU2012114854/15 A RU 2012114854/15A RU 2012114854 A RU2012114854 A RU 2012114854A RU 2012114854 A RU2012114854 A RU 2012114854A
- Authority
- RU
- Russia
- Prior art keywords
- individual
- antibody
- weeks
- psoriasis
- dose
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Dermatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US24228809P | 2009-09-14 | 2009-09-14 | |
| US61/242,288 | 2009-09-14 | ||
| US24596709P | 2009-09-25 | 2009-09-25 | |
| US61/245,967 | 2009-09-25 | ||
| US29762310P | 2010-01-22 | 2010-01-22 | |
| US61/297,623 | 2010-01-22 | ||
| US36029910P | 2010-06-30 | 2010-06-30 | |
| US61/360,299 | 2010-06-30 | ||
| PCT/US2010/048771 WO2011032148A1 (en) | 2009-09-14 | 2010-09-14 | Methods for treating psoriasis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU2012114854A true RU2012114854A (ru) | 2013-10-27 |
Family
ID=43732849
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2012114854/15A RU2012114854A (ru) | 2009-09-14 | 2010-09-14 | Способы лечения псориаза |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US8557239B2 (https=) |
| EP (1) | EP2477654A4 (https=) |
| JP (1) | JP2013504598A (https=) |
| KR (2) | KR20120112384A (https=) |
| CN (1) | CN102630168A (https=) |
| AU (1) | AU2010291927A1 (https=) |
| CA (1) | CA2773556A1 (https=) |
| IL (1) | IL218633A0 (https=) |
| IN (1) | IN2012DN01965A (https=) |
| MX (1) | MX2012003138A (https=) |
| NZ (1) | NZ598722A (https=) |
| RU (1) | RU2012114854A (https=) |
| SG (1) | SG179135A1 (https=) |
| TW (1) | TW201127400A (https=) |
| WO (1) | WO2011032148A1 (https=) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104524567A (zh) * | 2007-01-16 | 2015-04-22 | 阿布维公司 | 用于治疗银屑病的方法 |
| EP2274333A4 (en) * | 2008-03-18 | 2011-06-15 | Abbott Lab | PROCESS FOR TREATING PSORIASIS |
| JO3244B1 (ar) | 2009-10-26 | 2018-03-08 | Amgen Inc | بروتينات ربط مستضادات il – 23 البشرية |
| MX2013003920A (es) * | 2010-10-06 | 2013-06-03 | Abbvie Inc | Metodos para el tratamiento de la psoriasis. |
| EP2734236A4 (en) * | 2011-07-13 | 2015-04-15 | Abbvie Inc | METHOD AND COMPOSITIONS FOR TREATING ASTHMA WITH ANTI-IL-13 ANTIBODIES |
| EP2968488A1 (en) * | 2013-03-15 | 2016-01-20 | Amgen Inc. | Methods for treating psoriasis using an anti-il-23 antibody |
| AU2017332771A1 (en) * | 2016-09-23 | 2019-04-04 | Abbvie Inc. | Dose adjustment |
| IL274272B2 (en) | 2017-11-06 | 2025-09-01 | Janssen Biotech Inc | A safe and effective method for treating psoriatic arthritis with a specific anti-IL23 antibody |
| RU2697415C1 (ru) * | 2018-11-12 | 2019-08-14 | Федеральное государственное бюджетное военное образовательное учреждение высшего образования "Военно-медицинская академия имени С.М. Кирова" Министерства обороны Российской Федерации (ВМедА) | Способ лечения каплевидного псориаза |
| CN113015531A (zh) | 2018-11-15 | 2021-06-22 | 艾伯维公司 | 用于皮下施用的药物调配物 |
| JP7272557B2 (ja) * | 2020-12-24 | 2023-05-12 | 国立大学法人神戸大学 | 紫外線照射を用いたウイルス不活化方法 |
| BR112023018400A2 (pt) * | 2021-03-12 | 2023-12-12 | Janssen Biotech Inc | Método para tratamento de pacientes de artrite psoriática com resposta inadequada à terapia de tnf com anticorpo específico anti-il23 |
| MX2023010705A (es) * | 2021-03-12 | 2023-11-22 | Janssen Biotech Inc | Método seguro y eficaz para tratar la artritis psoriásica con el anticuerpo específico anti-il23. |
| AU2024262868A1 (en) * | 2023-04-26 | 2025-11-06 | Innovent Biologics (Suzhou) Co., Ltd. | Method for treating psoriasis with recombinant interleukin 23p19 antibody |
Family Cites Families (78)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8308235D0 (en) * | 1983-03-25 | 1983-05-05 | Celltech Ltd | Polypeptides |
| GB8823869D0 (en) * | 1988-10-12 | 1988-11-16 | Medical Res Council | Production of antibodies |
| US5811523A (en) * | 1988-11-10 | 1998-09-22 | Trinchieri; Giorgio | Antibodies to natural killer stimulatory factor |
| EP0368684B2 (en) | 1988-11-11 | 2004-09-29 | Medical Research Council | Cloning immunoglobulin variable domain sequences. |
| US5530101A (en) * | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| DK0494955T3 (da) * | 1989-10-05 | 1998-10-26 | Optein Inc | Cellefri syntese og isolering af hidtil ukendte gener og polypeptider |
| US6683046B1 (en) * | 1989-12-22 | 2004-01-27 | Hoffmann-La Roche Inc. | Purification and characterization of cytotoxic lymphocyte maturation factor and monoclonal antibodies thereto |
| US6150584A (en) * | 1990-01-12 | 2000-11-21 | Abgenix, Inc. | Human antibodies derived from immunized xenomice |
| US6713610B1 (en) * | 1990-01-12 | 2004-03-30 | Raju Kucherlapati | Human antibodies derived from immunized xenomice |
| US6673986B1 (en) * | 1990-01-12 | 2004-01-06 | Abgenix, Inc. | Generation of xenogeneic antibodies |
| GB9015198D0 (en) | 1990-07-10 | 1990-08-29 | Brien Caroline J O | Binding substance |
| EP0585287B1 (en) | 1990-07-10 | 1999-10-13 | Cambridge Antibody Technology Limited | Methods for producing members of specific binding pairs |
| US5661016A (en) * | 1990-08-29 | 1997-08-26 | Genpharm International Inc. | Transgenic non-human animals capable of producing heterologous antibodies of various isotypes |
| US5633425A (en) * | 1990-08-29 | 1997-05-27 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| US5814318A (en) * | 1990-08-29 | 1998-09-29 | Genpharm International Inc. | Transgenic non-human animals for producing heterologous antibodies |
| US7084260B1 (en) * | 1996-10-10 | 2006-08-01 | Genpharm International, Inc. | High affinity human antibodies and human antibodies against human antigens |
| US5789650A (en) * | 1990-08-29 | 1998-08-04 | Genpharm International, Inc. | Transgenic non-human animals for producing heterologous antibodies |
| US5770429A (en) | 1990-08-29 | 1998-06-23 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| US6300129B1 (en) * | 1990-08-29 | 2001-10-09 | Genpharm International | Transgenic non-human animals for producing heterologous antibodies |
| US6255458B1 (en) * | 1990-08-29 | 2001-07-03 | Genpharm International | High affinity human antibodies and human antibodies against digoxin |
| US5545806A (en) * | 1990-08-29 | 1996-08-13 | Genpharm International, Inc. | Ransgenic non-human animals for producing heterologous antibodies |
| ATE300615T1 (de) * | 1990-08-29 | 2005-08-15 | Genpharm Int | Transgene mäuse fähig zur produktion heterologer antikörper |
| US5625126A (en) * | 1990-08-29 | 1997-04-29 | Genpharm International, Inc. | Transgenic non-human animals for producing heterologous antibodies |
| CA2405246A1 (en) | 1990-12-03 | 1992-06-11 | Genentech, Inc. | Enrichment method for variant proteins with alterred binding properties |
| US6284471B1 (en) * | 1991-03-18 | 2001-09-04 | New York University Medical Center | Anti-TNFa antibodies and assays employing anti-TNFa antibodies |
| US6277969B1 (en) * | 1991-03-18 | 2001-08-21 | New York University | Anti-TNF antibodies and peptides of human tumor necrosis factor |
| US5919452A (en) * | 1991-03-18 | 1999-07-06 | New York University | Methods of treating TNFα-mediated disease using chimeric anti-TNF antibodies |
| US5698195A (en) * | 1991-03-18 | 1997-12-16 | New York University Medical Center | Methods of treating rheumatoid arthritis using chimeric anti-TNF antibodies |
| US5656272A (en) * | 1991-03-18 | 1997-08-12 | New York University Medical Center | Methods of treating TNF-α-mediated Crohn's disease using chimeric anti-TNF antibodies |
| WO1994004679A1 (en) | 1991-06-14 | 1994-03-03 | Genentech, Inc. | Method for making humanized antibodies |
| AU665025B2 (en) | 1991-09-23 | 1995-12-14 | Cambridge Antibody Technology Limited | Production of chimeric antibodies - a combinatorial approach |
| GB9122820D0 (en) * | 1991-10-28 | 1991-12-11 | Wellcome Found | Stabilised antibodies |
| ES2341666T3 (es) | 1991-12-02 | 2010-06-24 | Medimmune Limited | Produccion de autoanticuerpos de repertorios de segmentos de anticue rpos expresados en la superficie de fagos. |
| NZ255101A (en) | 1992-07-24 | 1997-08-22 | Cell Genesys Inc | A yeast artificial chromosome (yac) vector containing an hprt minigene expressible in murine stem cells and genetically modified rodent therefor |
| US5652138A (en) | 1992-09-30 | 1997-07-29 | The Scripps Research Institute | Human neutralizing monoclonal antibodies to human immunodeficiency virus |
| ES2159529T5 (es) * | 1993-03-05 | 2011-03-09 | Bayer Corporation | Anticuerpos monoclonales humanos anti-tnf alfa. |
| CA2161351C (en) | 1993-04-26 | 2010-12-21 | Nils Lonberg | Transgenic non-human animals capable of producing heterologous antibodies |
| CA2125763C (en) * | 1993-07-02 | 2007-08-28 | Maurice Kent Gately | P40 homodimer of interleukin-12 |
| EP0638644A1 (en) | 1993-07-19 | 1995-02-15 | F. Hoffmann-La Roche Ag | Receptors of interleukin-12 and antibodies |
| EP0659766A1 (en) | 1993-11-23 | 1995-06-28 | Schering-Plough | Human monoclonal antibodies against human cytokines and methods of making and using such antibodies |
| ZA95960B (en) | 1994-03-14 | 1995-10-10 | Genetics Inst | Use of interleukin-12 antagonists in the treatment of autoimmune diseases |
| US5910486A (en) * | 1994-09-06 | 1999-06-08 | Uab Research Foundation | Methods for modulating protein function in cells using, intracellular antibody homologues |
| US5562138A (en) * | 1994-10-13 | 1996-10-08 | The Longaberger Company | Bowing press |
| CA2219361C (en) | 1995-04-27 | 2012-02-28 | Abgenix, Inc. | Human antibodies derived from immunized xenomice |
| EP0823941A4 (en) | 1995-04-28 | 2001-09-19 | Abgenix Inc | HUMAN ANTIBODIES DERIVED FROM IMMUNIZED XENO MOUSES |
| US5670057A (en) | 1995-04-28 | 1997-09-23 | Baxter International Inc. | Apparatus and method for automatically performing peritoneal equilibration tests |
| US6685940B2 (en) * | 1995-07-27 | 2004-02-03 | Genentech, Inc. | Protein formulation |
| US5853697A (en) * | 1995-10-25 | 1998-12-29 | The United States Of America, As Represented By The Department Of Health & Human Services | Methods of treating established colitis using antibodies against IL-12 |
| US6297395B1 (en) * | 1995-11-10 | 2001-10-02 | The Secretary Of State For Defence In Her Brittanic Majesty's Government Of The United Kingdom Of Great Britain And Northern Ireland | Calixarenes and their use for sequestration of metals |
| US6090382A (en) * | 1996-02-09 | 2000-07-18 | Basf Aktiengesellschaft | Human antibodies that bind human TNFα |
| DK0929578T3 (da) * | 1996-02-09 | 2003-08-25 | Abbott Lab Bermuda Ltd | Humane antistoffer, der binder human TNFalfa |
| WO1998016248A1 (en) | 1996-10-11 | 1998-04-23 | The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services | Methods for enhancing oral tolerance and treating autoimmune disease using inhibitors of interleukin-12 |
| PT936923E (pt) | 1996-11-15 | 2004-04-30 | Kennedy Inst Of Rheumatology | Supressao de tnfalfa e il-12 em terapia |
| EP1500329B1 (en) * | 1996-12-03 | 2012-03-21 | Amgen Fremont Inc. | Human antibodies that specifically bind human TNF alpha |
| US6054487A (en) * | 1997-03-18 | 2000-04-25 | Basf Aktiengesellschaft | Methods and compositions for modulating responsiveness to corticosteroids |
| WO1999037682A2 (en) * | 1998-01-23 | 1999-07-29 | F.Hoffmann-La Roche Ag | Antibodies against human il-12 |
| US20020161199A1 (en) * | 1998-04-08 | 2002-10-31 | Genentech, Inc. | Compositions and methods for the diagnosis and treatment of tumor |
| EP0953639A1 (en) | 1998-04-30 | 1999-11-03 | Boehringer Ingelheim International GmbH | FAPalpha-specific antibody with improved producibility |
| JP3579355B2 (ja) * | 1998-12-09 | 2004-10-20 | プロテイン デザイン ラブス インコーポレイティド | ヒトの乾癬を予防及び治療するための乾癬モデル動物 |
| US6914128B1 (en) * | 1999-03-25 | 2005-07-05 | Abbott Gmbh & Co. Kg | Human antibodies that bind human IL-12 and methods for producing |
| SI2168984T1 (sl) * | 1999-03-25 | 2012-12-31 | Abbott Gmbh & Co. Kg | Človeška protitelesa za vezavo IL-12 in postopki izdelave |
| US7883704B2 (en) * | 1999-03-25 | 2011-02-08 | Abbott Gmbh & Co. Kg | Methods for inhibiting the activity of the P40 subunit of human IL-12 |
| US6902734B2 (en) * | 2000-08-07 | 2005-06-07 | Centocor, Inc. | Anti-IL-12 antibodies and compositions thereof |
| JP5052736B2 (ja) * | 2001-05-30 | 2012-10-17 | 中外製薬株式会社 | タンパク質製剤 |
| CA2492143A1 (en) * | 2002-07-12 | 2004-01-22 | Medarex, Inc. | Methods and compositions for preventing oxidative degradation of proteins |
| US7608260B2 (en) * | 2003-01-06 | 2009-10-27 | Medimmune, Llc | Stabilized immunoglobulins |
| CN100522998C (zh) * | 2003-10-01 | 2009-08-05 | 协和发酵麒麟株式会社 | 抗体的稳定化方法和被稳定的溶液状抗体制剂 |
| EP1694317A4 (en) * | 2003-12-19 | 2010-05-12 | Protemix Corp Ltd | COPPER ANTAGONIST COMPOUNDS |
| RU2390353C2 (ru) * | 2004-02-12 | 2010-05-27 | Мерк Патент Гмбх | Высококонцентрированные жидкие композиции анти-egfr антител |
| SG158150A1 (en) * | 2004-12-21 | 2010-01-29 | Centocor Inc | Anti-il-12 antibodies, epitopes, compositions, methods and uses |
| AU2006265002B2 (en) * | 2005-06-30 | 2012-09-20 | Centocor, Inc. | Anti-IL-23 antibodies, compositions, methods and uses |
| CA2638811A1 (en) * | 2006-02-03 | 2007-08-16 | Medimmune, Llc | Protein formulations |
| CN104524567A (zh) * | 2007-01-16 | 2015-04-22 | 阿布维公司 | 用于治疗银屑病的方法 |
| CA2681752A1 (en) * | 2007-03-29 | 2008-10-09 | Abbott Laboratories | Crystalline anti-human 1l-12 antibodies |
| EP2274333A4 (en) * | 2008-03-18 | 2011-06-15 | Abbott Lab | PROCESS FOR TREATING PSORIASIS |
| WO2010062896A1 (en) * | 2008-11-28 | 2010-06-03 | Abbott Laboratories | Stable antibody compositions and methods for stabilizing same |
| MX2013003920A (es) * | 2010-10-06 | 2013-06-03 | Abbvie Inc | Metodos para el tratamiento de la psoriasis. |
| TW201309330A (zh) * | 2011-01-28 | 2013-03-01 | Abbott Lab | 包含糖基化抗體之組合物及其用途 |
-
2010
- 2010-09-14 KR KR1020127009659A patent/KR20120112384A/ko not_active Ceased
- 2010-09-14 CA CA2773556A patent/CA2773556A1/en not_active Abandoned
- 2010-09-14 CN CN2010800514147A patent/CN102630168A/zh active Pending
- 2010-09-14 IN IN1965DEN2012 patent/IN2012DN01965A/en unknown
- 2010-09-14 JP JP2012528988A patent/JP2013504598A/ja active Pending
- 2010-09-14 MX MX2012003138A patent/MX2012003138A/es active IP Right Grant
- 2010-09-14 AU AU2010291927A patent/AU2010291927A1/en not_active Abandoned
- 2010-09-14 KR KR1020147002833A patent/KR20140048229A/ko not_active Withdrawn
- 2010-09-14 NZ NZ598722A patent/NZ598722A/en not_active IP Right Cessation
- 2010-09-14 TW TW099131092A patent/TW201127400A/zh unknown
- 2010-09-14 US US12/881,902 patent/US8557239B2/en not_active Expired - Fee Related
- 2010-09-14 SG SG2012017950A patent/SG179135A1/en unknown
- 2010-09-14 RU RU2012114854/15A patent/RU2012114854A/ru unknown
- 2010-09-14 WO PCT/US2010/048771 patent/WO2011032148A1/en not_active Ceased
- 2010-09-14 EP EP10816272A patent/EP2477654A4/en not_active Withdrawn
-
2012
- 2012-03-14 IL IL218633A patent/IL218633A0/en unknown
-
2013
- 2013-09-11 US US14/023,590 patent/US20140079714A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| JP2013504598A (ja) | 2013-02-07 |
| WO2011032148A1 (en) | 2011-03-17 |
| NZ598722A (en) | 2014-05-30 |
| CA2773556A1 (en) | 2011-03-17 |
| IN2012DN01965A (https=) | 2015-08-21 |
| US8557239B2 (en) | 2013-10-15 |
| EP2477654A1 (en) | 2012-07-25 |
| SG179135A1 (en) | 2012-05-30 |
| MX2012003138A (es) | 2012-07-04 |
| TW201127400A (en) | 2011-08-16 |
| EP2477654A4 (en) | 2013-01-23 |
| US20110206680A1 (en) | 2011-08-25 |
| IL218633A0 (en) | 2012-05-31 |
| CN102630168A (zh) | 2012-08-08 |
| KR20140048229A (ko) | 2014-04-23 |
| KR20120112384A (ko) | 2012-10-11 |
| US20140079714A1 (en) | 2014-03-20 |
| AU2010291927A1 (en) | 2012-04-12 |
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