RU2010140353A - КОМПОЗИЦИИ, ВКЛЮЧАЮЩИЕ ИНГИБИТОР NFкВ И СТИМУЛЯТОР ОБРАЗОВАНИЯ ТРОПОЭЛАСТИНА - Google Patents

КОМПОЗИЦИИ, ВКЛЮЧАЮЩИЕ ИНГИБИТОР NFкВ И СТИМУЛЯТОР ОБРАЗОВАНИЯ ТРОПОЭЛАСТИНА Download PDF

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RU2010140353A
RU2010140353A RU2010140353/15A RU2010140353A RU2010140353A RU 2010140353 A RU2010140353 A RU 2010140353A RU 2010140353/15 A RU2010140353/15 A RU 2010140353/15A RU 2010140353 A RU2010140353 A RU 2010140353A RU 2010140353 A RU2010140353 A RU 2010140353A
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inhibitor
nfĸb
tropoelastin
stimulator
substituted resorcinol
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RU2010140353/15A
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RU2572505C2 (ru
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Симарна КАУР (US)
Симарна КАУР
Майкл САУТХОЛЛ (US)
Майкл САУТХОЛЛ
Саманта ТАКЕР-САМАРАС (US)
Саманта ТАКЕР-САМАРАС
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Джонсон Энд Джонсон Конзьюмер Компаниз, Инк. (Us)
Джонсон Энд Джонсон Конзьюмер Компаниз, Инк.
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34—Alcohols
    • A61K8/347—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/45—Ericaceae or Vacciniaceae (Heath or Blueberry family), e.g. blueberry, cranberry or bilberry
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/35—Ketones, e.g. benzophenone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/46—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur
    • A61K8/466—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur containing sulfonic acid derivatives; Salts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783—Angiosperms [Magnoliophyta]
    • A61K8/9789—Magnoliopsida [dicotyledons]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations

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  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
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Abstract

1. Композиция, включающая: ! ингибитор NFĸB; и ! стимулятор образования тропоэластина. ! 2. Композиция по п.1, в которой ингибитор NFĸB выбран из группы, состоящей из замещенных резорцинов, (E)-3-(4-метилфенилсульфонил)-2-пропеннитрила, тетрагидрокуркуминоидов, а также их комбинаций. ! 3. Композиция по п.1, в которой ингибитор NFĸB представляет собой замещенный резорцин. ! 4. Композиция по п.3, в которой замещенный резорцин представляет собой 4-гексилрезорцин. ! 5. Композиция по п.1, в которой стимулятор образования тропоэластина выбран из группы, состоящей из экстрактов ежевики, экстрактов скумпии, экстрактов пиретрума, экстрактов Phyllanthus niruri, а также их комбинаций. ! 6. Композиция по п.1, в которой ингибитор NFĸB и стимулятор образования тропоэластина присутствуют в концентрации в весовом соотношении от приблизительно 0,001 до приблизительно 100. ! 7. Способ лечения признаков старения кожи, включающий топическое нанесение на кожу, нуждающуюся в таком лечении, композиции, включающей ингибитор NFĸB и стимулятор образования тропоэластина. ! 8. Способ по п.7, в котором ингибитор NFĸB выбран из группы, состоящей из замещенных резорцинов, (E)-3-(4-метилфенилсульфонил)-2-пропеннитрила, тетрагидрокуркуминоидов, а также их комбинаций. ! 9. Способ по п.7, в котором ингибитор NFĸB представляет собой замещенный резорцин. ! 10. Способ по п.9, в котором замещенный резорцин представляет собой 4-гексилрезорцин.

Claims (10)

1. Композиция, включающая:
ингибитор NFĸB; и
стимулятор образования тропоэластина.
2. Композиция по п.1, в которой ингибитор NFĸB выбран из группы, состоящей из замещенных резорцинов, (E)-3-(4-метилфенилсульфонил)-2-пропеннитрила, тетрагидрокуркуминоидов, а также их комбинаций.
3. Композиция по п.1, в которой ингибитор NFĸB представляет собой замещенный резорцин.
4. Композиция по п.3, в которой замещенный резорцин представляет собой 4-гексилрезорцин.
5. Композиция по п.1, в которой стимулятор образования тропоэластина выбран из группы, состоящей из экстрактов ежевики, экстрактов скумпии, экстрактов пиретрума, экстрактов Phyllanthus niruri, а также их комбинаций.
6. Композиция по п.1, в которой ингибитор NFĸB и стимулятор образования тропоэластина присутствуют в концентрации в весовом соотношении от приблизительно 0,001 до приблизительно 100.
7. Способ лечения признаков старения кожи, включающий топическое нанесение на кожу, нуждающуюся в таком лечении, композиции, включающей ингибитор NFĸB и стимулятор образования тропоэластина.
8. Способ по п.7, в котором ингибитор NFĸB выбран из группы, состоящей из замещенных резорцинов, (E)-3-(4-метилфенилсульфонил)-2-пропеннитрила, тетрагидрокуркуминоидов, а также их комбинаций.
9. Способ по п.7, в котором ингибитор NFĸB представляет собой замещенный резорцин.
10. Способ по п.9, в котором замещенный резорцин представляет собой 4-гексилрезорцин.
RU2010140353/15A 2009-10-02 2010-10-01 КОМПОЗИЦИИ, ВКЛЮЧАЮЩИЕ ИНГИБИТОР NFкВ И СТИМУЛЯТОР ОБРАЗОВАНИЯ ТРОПОЭЛАСТИНА RU2572505C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12/572,545 2009-10-02
US12/572,545 US20110081430A1 (en) 2009-10-02 2009-10-02 COMPOSITIONS COMPRISING AN NFkB-INHIBITOR AND A TROPOELASTIN PROMOTER

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RU2010140353A true RU2010140353A (ru) 2012-04-10
RU2572505C2 RU2572505C2 (ru) 2016-01-10

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US (3) US20110081430A1 (ru)
EP (1) EP2319488B1 (ru)
KR (1) KR101740290B1 (ru)
CN (1) CN102113978B (ru)
BR (1) BRPI1010464A2 (ru)
CA (1) CA2716669C (ru)
ES (1) ES2598153T3 (ru)
HK (1) HK1158966A1 (ru)
RU (1) RU2572505C2 (ru)

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KR101740290B1 (ko) 2017-05-26
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EP2319488B1 (en) 2016-07-20
US9629794B2 (en) 2017-04-25
US9375395B2 (en) 2016-06-28
CA2716669A1 (en) 2011-04-02
CA2716669C (en) 2017-11-21
CN102113978A (zh) 2011-07-06
US20130171281A1 (en) 2013-07-04
US20150064292A1 (en) 2015-03-05
HK1158966A1 (en) 2012-07-27
BRPI1010464A2 (pt) 2013-04-09
US20110081430A1 (en) 2011-04-07
RU2572505C2 (ru) 2016-01-10
KR20110036685A (ko) 2011-04-08
ES2598153T3 (es) 2017-01-25

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