RU2008130370A - Питательные композиции для младенцев для предупреждения ожирения - Google Patents
Питательные композиции для младенцев для предупреждения ожирения Download PDFInfo
- Publication number
- RU2008130370A RU2008130370A RU2008130370/13A RU2008130370A RU2008130370A RU 2008130370 A RU2008130370 A RU 2008130370A RU 2008130370/13 A RU2008130370/13 A RU 2008130370/13A RU 2008130370 A RU2008130370 A RU 2008130370A RU 2008130370 A RU2008130370 A RU 2008130370A
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- Russia
- Prior art keywords
- use according
- composition
- fatty acids
- total mass
- obesity
- Prior art date
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- 239000000203 mixture Substances 0.000 title claims abstract 27
- 208000008589 Obesity Diseases 0.000 title claims abstract 8
- 235000020824 obesity Nutrition 0.000 title claims abstract 8
- 235000016709 nutrition Nutrition 0.000 title claims abstract 5
- 230000002265 prevention Effects 0.000 title 1
- DRTQHJPVMGBUCF-XVFCMESISA-N Uridine Chemical compound O[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1N1C(=O)NC(=O)C=C1 DRTQHJPVMGBUCF-XVFCMESISA-N 0.000 claims abstract 12
- DTOSIQBPPRVQHS-PDBXOOCHSA-N alpha-linolenic acid Chemical compound CC\C=C/C\C=C/C\C=C/CCCCCCCC(O)=O DTOSIQBPPRVQHS-PDBXOOCHSA-N 0.000 claims abstract 8
- 235000014113 dietary fatty acids Nutrition 0.000 claims abstract 8
- 229930195729 fatty acid Natural products 0.000 claims abstract 8
- 239000000194 fatty acid Substances 0.000 claims abstract 8
- 150000004665 fatty acids Chemical class 0.000 claims abstract 8
- OYHQOLUKZRVURQ-HZJYTTRNSA-N Linoleic acid Chemical compound CCCCC\C=C/C\C=C/CCCCCCCC(O)=O OYHQOLUKZRVURQ-HZJYTTRNSA-N 0.000 claims abstract 6
- 235000020661 alpha-linolenic acid Nutrition 0.000 claims abstract 6
- DRTQHJPVMGBUCF-PSQAKQOGSA-N beta-L-uridine Natural products O[C@H]1[C@@H](O)[C@H](CO)O[C@@H]1N1C(=O)NC(=O)C=C1 DRTQHJPVMGBUCF-PSQAKQOGSA-N 0.000 claims abstract 6
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 claims abstract 6
- 235000019197 fats Nutrition 0.000 claims abstract 6
- 235000020778 linoleic acid Nutrition 0.000 claims abstract 6
- OYHQOLUKZRVURQ-IXWMQOLASA-N linoleic acid Natural products CCCCC\C=C/C\C=C\CCCCCCCC(O)=O OYHQOLUKZRVURQ-IXWMQOLASA-N 0.000 claims abstract 6
- DRTQHJPVMGBUCF-UHFFFAOYSA-N uracil arabinoside Natural products OC1C(O)C(CO)OC1N1C(=O)NC(=O)C=C1 DRTQHJPVMGBUCF-UHFFFAOYSA-N 0.000 claims abstract 6
- 229940045145 uridine Drugs 0.000 claims abstract 6
- 150000002632 lipids Chemical class 0.000 claims abstract 5
- OEYIOHPDSNJKLS-UHFFFAOYSA-N choline Chemical compound C[N+](C)(C)CCO OEYIOHPDSNJKLS-UHFFFAOYSA-N 0.000 claims abstract 4
- 229960001231 choline Drugs 0.000 claims abstract 4
- 229960004488 linolenic acid Drugs 0.000 claims abstract 4
- 150000003904 phospholipids Chemical class 0.000 claims abstract 4
- 150000001720 carbohydrates Chemical class 0.000 claims abstract 3
- 235000014633 carbohydrates Nutrition 0.000 claims abstract 3
- 235000004252 protein component Nutrition 0.000 claims abstract 3
- VMHLLURERBWHNL-UHFFFAOYSA-M Sodium acetate Chemical compound [Na+].CC([O-])=O VMHLLURERBWHNL-UHFFFAOYSA-M 0.000 claims abstract 2
- DJJCXFVJDGTHFX-UHFFFAOYSA-N Uridinemonophosphate Natural products OC1C(O)C(COP(O)(O)=O)OC1N1C(=O)NC(=O)C=C1 DJJCXFVJDGTHFX-UHFFFAOYSA-N 0.000 claims abstract 2
- 235000012000 cholesterol Nutrition 0.000 claims abstract 2
- 235000020978 long-chain polyunsaturated fatty acids Nutrition 0.000 claims abstract 2
- 150000004667 medium chain fatty acids Chemical class 0.000 claims abstract 2
- 239000002777 nucleoside Chemical class 0.000 claims abstract 2
- 150000003833 nucleoside derivatives Chemical class 0.000 claims abstract 2
- 239000002773 nucleotide Substances 0.000 claims abstract 2
- 125000003729 nucleotide group Chemical class 0.000 claims abstract 2
- 150000003408 sphingolipids Chemical class 0.000 claims abstract 2
- DJJCXFVJDGTHFX-XVFCMESISA-N uridine 5'-monophosphate Chemical group O[C@@H]1[C@H](O)[C@@H](COP(O)(O)=O)O[C@H]1N1C(=O)NC(=O)C=C1 DJJCXFVJDGTHFX-XVFCMESISA-N 0.000 claims abstract 2
- 229920001542 oligosaccharide Polymers 0.000 claims 8
- 150000002482 oligosaccharides Chemical class 0.000 claims 4
- RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical class OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 claims 2
- 235000021255 galacto-oligosaccharides Nutrition 0.000 claims 2
- 150000003271 galactooligosaccharides Chemical class 0.000 claims 2
- 201000001320 Atherosclerosis Diseases 0.000 claims 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims 1
- 208000024172 Cardiovascular disease Diseases 0.000 claims 1
- 229920001202 Inulin Polymers 0.000 claims 1
- 239000002253 acid Substances 0.000 claims 1
- SQVRNKJHWKZAKO-UHFFFAOYSA-N beta-N-Acetyl-D-neuraminic acid Natural products CC(=O)NC1C(O)CC(O)(C(O)=O)OC1C(O)C(O)CO SQVRNKJHWKZAKO-UHFFFAOYSA-N 0.000 claims 1
- 239000008280 blood Substances 0.000 claims 1
- 210000004369 blood Anatomy 0.000 claims 1
- 229910052791 calcium Inorganic materials 0.000 claims 1
- 239000011575 calcium Substances 0.000 claims 1
- JYJIGFIDKWBXDU-MNNPPOADSA-N inulin Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)OC[C@]1(OC[C@]2(OC[C@]3(OC[C@]4(OC[C@]5(OC[C@]6(OC[C@]7(OC[C@]8(OC[C@]9(OC[C@]%10(OC[C@]%11(OC[C@]%12(OC[C@]%13(OC[C@]%14(OC[C@]%15(OC[C@]%16(OC[C@]%17(OC[C@]%18(OC[C@]%19(OC[C@]%20(OC[C@]%21(OC[C@]%22(OC[C@]%23(OC[C@]%24(OC[C@]%25(OC[C@]%26(OC[C@]%27(OC[C@]%28(OC[C@]%29(OC[C@]%30(OC[C@]%31(OC[C@]%32(OC[C@]%33(OC[C@]%34(OC[C@]%35(OC[C@]%36(O[C@@H]%37[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O%37)O)[C@H]([C@H](O)[C@@H](CO)O%36)O)[C@H]([C@H](O)[C@@H](CO)O%35)O)[C@H]([C@H](O)[C@@H](CO)O%34)O)[C@H]([C@H](O)[C@@H](CO)O%33)O)[C@H]([C@H](O)[C@@H](CO)O%32)O)[C@H]([C@H](O)[C@@H](CO)O%31)O)[C@H]([C@H](O)[C@@H](CO)O%30)O)[C@H]([C@H](O)[C@@H](CO)O%29)O)[C@H]([C@H](O)[C@@H](CO)O%28)O)[C@H]([C@H](O)[C@@H](CO)O%27)O)[C@H]([C@H](O)[C@@H](CO)O%26)O)[C@H]([C@H](O)[C@@H](CO)O%25)O)[C@H]([C@H](O)[C@@H](CO)O%24)O)[C@H]([C@H](O)[C@@H](CO)O%23)O)[C@H]([C@H](O)[C@@H](CO)O%22)O)[C@H]([C@H](O)[C@@H](CO)O%21)O)[C@H]([C@H](O)[C@@H](CO)O%20)O)[C@H]([C@H](O)[C@@H](CO)O%19)O)[C@H]([C@H](O)[C@@H](CO)O%18)O)[C@H]([C@H](O)[C@@H](CO)O%17)O)[C@H]([C@H](O)[C@@H](CO)O%16)O)[C@H]([C@H](O)[C@@H](CO)O%15)O)[C@H]([C@H](O)[C@@H](CO)O%14)O)[C@H]([C@H](O)[C@@H](CO)O%13)O)[C@H]([C@H](O)[C@@H](CO)O%12)O)[C@H]([C@H](O)[C@@H](CO)O%11)O)[C@H]([C@H](O)[C@@H](CO)O%10)O)[C@H]([C@H](O)[C@@H](CO)O9)O)[C@H]([C@H](O)[C@@H](CO)O8)O)[C@H]([C@H](O)[C@@H](CO)O7)O)[C@H]([C@H](O)[C@@H](CO)O6)O)[C@H]([C@H](O)[C@@H](CO)O5)O)[C@H]([C@H](O)[C@@H](CO)O4)O)[C@H]([C@H](O)[C@@H](CO)O3)O)[C@H]([C@H](O)[C@@H](CO)O2)O)[C@@H](O)[C@H](O)[C@@H](CO)O1 JYJIGFIDKWBXDU-MNNPPOADSA-N 0.000 claims 1
- 229940029339 inulin Drugs 0.000 claims 1
- -1 inulin) Chemical class 0.000 claims 1
- 150000003272 mannan oligosaccharides Chemical class 0.000 claims 1
- SQVRNKJHWKZAKO-OQPLDHBCSA-N sialic acid Chemical compound CC(=O)N[C@@H]1[C@@H](O)C[C@@](O)(C(O)=O)OC1[C@H](O)[C@H](O)CO SQVRNKJHWKZAKO-OQPLDHBCSA-N 0.000 claims 1
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- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
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- Urology & Nephrology (AREA)
Abstract
1. Применение композиции, включающей липидный компонент, белковый компонент и компонент усвояемых углеводов, где липидный компонент включает: ! (i) линолевую кислоту (ЛК) и альфа-линоленовую кислоту (АЛК) в массовом соотношении ЛК/АЛК от 2 до 7; ! (ii) менее чем 14,5 мас.% ЛК от общей массы жирных кислот; и ! (iii) по меньшей мере, 1 мас.% АЛК от общей массы жирных кислот, ! и где композиция дополнительно включает, по меньшей мере, один компонент, выбранный из группы, состоящей из: ! (a) от 0,5 до 20 мас.% фосфолипидов от общей массы жира; ! (b) от 0,035 до 1 мас.% холина от общей массы сухой композиции; ! и от 0,001 до 0,1 мас.% уридина в форме нуклеотида, нуклеозида и/или основания от общей массы сухой композиции для получения питательной композиции для введения не страдающему ожирением младенцу в возрасте менее 36 месяцев для предупреждения ожирения. ! 2. Применение по п.1, где композиция включает холин, источник уридина и фосфолипидов. ! 3. Применение по любому из предшествующих пунктов, где композиция дополнительно включает: ! (c) от 0,5 до 20 мас.% сфинголипидов от общей массы жира; и/или ! (d) от 0,005 до 10 мас.% холестерина от общей массы жира. ! 4. Применение по п.1 или 2, где источником уридина является монофосфат уридина. ! 5. Применение по п.1 или 2, для предупреждения развития ожирения на более позднем этапе жизни и/или для предупреждения развития ожирения, когда возраст указанного младенца составляет более 36 месяцев. ! 6. Применение по п.1 или 2, где композиция дополнительно включает: ! (i) от 3 до 50 мас.% среднецепочечных жирных кислот (СЦЖК) от общей массы жирных кислот, и/или ! (ii) n-6 длинноцепочечные полиненасыщенные жирные кислоты (ДЦ-ПНЖК) и n-3 ДЦ-ПНЖК в массовом соотношен�
Claims (16)
1. Применение композиции, включающей липидный компонент, белковый компонент и компонент усвояемых углеводов, где липидный компонент включает:
(i) линолевую кислоту (ЛК) и альфа-линоленовую кислоту (АЛК) в массовом соотношении ЛК/АЛК от 2 до 7;
(ii) менее чем 14,5 мас.% ЛК от общей массы жирных кислот; и
(iii) по меньшей мере, 1 мас.% АЛК от общей массы жирных кислот,
и где композиция дополнительно включает, по меньшей мере, один компонент, выбранный из группы, состоящей из:
(a) от 0,5 до 20 мас.% фосфолипидов от общей массы жира;
(b) от 0,035 до 1 мас.% холина от общей массы сухой композиции;
и от 0,001 до 0,1 мас.% уридина в форме нуклеотида, нуклеозида и/или основания от общей массы сухой композиции для получения питательной композиции для введения не страдающему ожирением младенцу в возрасте менее 36 месяцев для предупреждения ожирения.
2. Применение по п.1, где композиция включает холин, источник уридина и фосфолипидов.
3. Применение по любому из предшествующих пунктов, где композиция дополнительно включает:
(c) от 0,5 до 20 мас.% сфинголипидов от общей массы жира; и/или
(d) от 0,005 до 10 мас.% холестерина от общей массы жира.
4. Применение по п.1 или 2, где источником уридина является монофосфат уридина.
5. Применение по п.1 или 2, для предупреждения развития ожирения на более позднем этапе жизни и/или для предупреждения развития ожирения, когда возраст указанного младенца составляет более 36 месяцев.
6. Применение по п.1 или 2, где композиция дополнительно включает:
(i) от 3 до 50 мас.% среднецепочечных жирных кислот (СЦЖК) от общей массы жирных кислот, и/или
(ii) n-6 длинноцепочечные полиненасыщенные жирные кислоты (ДЦ-ПНЖК) и n-3 ДЦ-ПНЖК в массовом соотношении менее 1,5; от 0,02 до 0,8 мас.% n-6 ДЦ-ПНЖК от общей массы жирных кислот и, по меньшей мере, 0, 2 мас.% n-3 ДЦ-ПНЖК от общей массы жирных кислот.
7. Применение по п.1 или 2, где липидный компонент обеспечивает от 35 до 55% всех калорий, белковый компонент обеспечивает от 5 до 15% всех калорий и компонент усвояемых углеводов обеспечивает от 30 до 60% всех калорий.
8. Применение по п.1 или 2, где композиция обеспечивает 60-90 ккал/100 мл.
9. Применение по п.1 или 2, для предупреждения развития ожирения у людей в возрасте старше 12 лет.
10. Применение по п.1 или 2, где питательную композицию вводят младенцам в возрасте менее 12 месяцев.
11. Применение по п.1 или 2, где композиция дополнительно включает, по меньшей мере, 0,5 мас.% от общей массы сухой композиции, по меньшей мере, одного растворимого, неусвояемого олигосахарида.
12. Применение по п.1 или 2, где композиция включает, по меньшей мере, 0,5 мас.%, по меньшей мере, одного растворимого, неусвояемого олигосахарида, выбранного из группы, состоящей из фруктоолигосахаридов (включая инулин), галактоолигосахаридов (включая трансгалактоолигосахариды), глюкоолигосахаридов (включая гентио-, нигеро- и циклодекстринолигосахариды), арабиноолигосахаридов, маннанолигосахаридов, ксилоолигосахаридов, фукоолигосахаридов, арабиногалактоолигосахаридов, глюкоманноолигосахаридов, галактоманноолигосахаридов, олигосахаридов, включающих сиаловую кислоту, и олигосахаридов, включающих уроновую кислоту.
13. Применение по п.1 или 2, где композиция включает галактоолигосахариды.
14. Применение по п.1 или 2, где композиция дополнительно включает фруктоолигосахариды.
15. Применение по п.1 или 2, где композиция включает, по меньшей мере, 0,3 мас.% кальция от общей массы сухой композиции.
16. Применение по п.1 или 2, гдепитательную композицию вводят младенцу в возрасте менее 36 месяцев для предупреждения сердечно-сосудистых заболеваний, атеросклероза и/или высокого уровня холестерина в крови на более позднем этапе жизни.
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RU2008130367/15A RU2414905C2 (ru) | 2005-12-23 | 2006-12-22 | Применение питательных композиций с фосфолипидами, сфинголипидами и холестерином |
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2006
- 2006-12-22 WO PCT/NL2006/050329 patent/WO2007073193A2/en active Application Filing
- 2006-12-22 US US12/158,931 patent/US20090186803A1/en not_active Abandoned
- 2006-12-22 ES ES06824326.0T patent/ES2537080T3/es active Active
- 2006-12-22 JP JP2008547136A patent/JP2009521214A/ja active Pending
- 2006-12-22 RU RU2008130365/13A patent/RU2444210C2/ru not_active IP Right Cessation
- 2006-12-22 US US12/158,857 patent/US20110136732A1/en not_active Abandoned
- 2006-12-22 BR BRPI0620465-1A patent/BRPI0620465A2/pt not_active Application Discontinuation
- 2006-12-22 WO PCT/NL2006/050331 patent/WO2007073194A2/en active Application Filing
- 2006-12-22 PT PT68243260T patent/PT1962823E/pt unknown
- 2006-12-22 MY MYPI20082246A patent/MY149164A/en unknown
- 2006-12-22 EP EP06824326.0A patent/EP1962823B1/en not_active Revoked
- 2006-12-22 HU HUE06824326A patent/HUE026440T2/en unknown
- 2006-12-22 EP EP11150747A patent/EP2305049A1/en not_active Withdrawn
- 2006-12-22 AU AU2006327996A patent/AU2006327996B2/en active Active
- 2006-12-22 CA CA002634117A patent/CA2634117A1/en not_active Abandoned
- 2006-12-22 WO PCT/NL2006/050328 patent/WO2007073192A2/en active Application Filing
- 2006-12-22 EP EP06824324.5A patent/EP1973424B1/en active Active
- 2006-12-22 RU RU2008130367/15A patent/RU2414905C2/ru not_active IP Right Cessation
- 2006-12-22 CA CA002634693A patent/CA2634693A1/en not_active Abandoned
- 2006-12-22 BR BRPI0620466-0A patent/BRPI0620466A2/pt not_active Application Discontinuation
- 2006-12-22 EP EP06824323A patent/EP1962617A2/en not_active Withdrawn
- 2006-12-22 BR BRPI0620451-1A patent/BRPI0620451A2/pt not_active IP Right Cessation
- 2006-12-22 RU RU2008130370/13A patent/RU2417712C2/ru active
- 2006-12-22 CA CA002634895A patent/CA2634895A1/en not_active Abandoned
- 2006-12-22 CN CN201310014398.XA patent/CN103054048B/zh active Active
- 2006-12-22 PL PL06824326T patent/PL1962823T3/pl unknown
- 2006-12-22 AU AU2006327995A patent/AU2006327995B2/en not_active Ceased
- 2006-12-22 AU AU2006327997A patent/AU2006327997B2/en active Active
- 2006-12-23 MY MYPI20082287A patent/MY162091A/en unknown
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2012
- 2012-01-24 US US13/357,109 patent/US8871218B2/en active Active
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2598707C2 (ru) * | 2011-04-19 | 2016-09-27 | Нестек С.А. | Детская смесь для применения в профилактике сердечно-сосудистых заболеваний |
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