RU2007133709A - Производные в-циклодекстрина в качестве антибактериальных агентов - Google Patents
Производные в-циклодекстрина в качестве антибактериальных агентов Download PDFInfo
- Publication number
- RU2007133709A RU2007133709A RU2007133709/04A RU2007133709A RU2007133709A RU 2007133709 A RU2007133709 A RU 2007133709A RU 2007133709/04 A RU2007133709/04 A RU 2007133709/04A RU 2007133709 A RU2007133709 A RU 2007133709A RU 2007133709 A RU2007133709 A RU 2007133709A
- Authority
- RU
- Russia
- Prior art keywords
- alkyl
- aralkyl
- aryl
- ness
- aminoalkyl
- Prior art date
Links
- 239000003242 anti bacterial agent Substances 0.000 title claims 2
- WHGYBXFWUBPSRW-FOUAGVGXSA-N beta-cyclodextrin Chemical class OC[C@H]([C@H]([C@@H]([C@H]1O)O)O[C@H]2O[C@@H]([C@@H](O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O3)[C@H](O)[C@H]2O)CO)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@@H]3O[C@@H]1CO WHGYBXFWUBPSRW-FOUAGVGXSA-N 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 claims 27
- 125000003710 aryl alkyl group Chemical group 0.000 claims 14
- 125000003118 aryl group Chemical group 0.000 claims 14
- 229910052757 nitrogen Inorganic materials 0.000 claims 14
- 125000000623 heterocyclic group Chemical group 0.000 claims 9
- 241000124008 Mammalia Species 0.000 claims 8
- 150000001875 compounds Chemical class 0.000 claims 8
- 125000004433 nitrogen atom Chemical group N* 0.000 claims 7
- 125000004430 oxygen atom Chemical group O* 0.000 claims 7
- 125000004434 sulfur atom Chemical group 0.000 claims 7
- 241000894006 Bacteria Species 0.000 claims 5
- 125000004432 carbon atom Chemical group C* 0.000 claims 5
- 125000005343 heterocyclic alkyl group Chemical group 0.000 claims 5
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 5
- 229910052760 oxygen Inorganic materials 0.000 claims 5
- 125000001424 substituent group Chemical group 0.000 claims 5
- 229910052717 sulfur Inorganic materials 0.000 claims 5
- 208000035143 Bacterial infection Diseases 0.000 claims 4
- 125000004103 aminoalkyl group Chemical group 0.000 claims 4
- 208000022362 bacterial infectious disease Diseases 0.000 claims 4
- 229910052739 hydrogen Inorganic materials 0.000 claims 4
- 125000004429 atom Chemical group 0.000 claims 3
- 230000003115 biocidal effect Effects 0.000 claims 3
- -1 (ness.) O-alkyl Chemical group 0.000 claims 1
- 230000001580 bacterial effect Effects 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 230000000694 effects Effects 0.000 claims 1
- 230000002401 inhibitory effect Effects 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 230000003389 potentiating effect Effects 0.000 claims 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
- C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/716—Glucans
- A61K31/724—Cyclodextrins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
- C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
- C08B37/0012—Cyclodextrin [CD], e.g. cycle with 6 units (alpha), with 7 units (beta) and with 8 units (gamma), large-ring cyclodextrin or cycloamylose with 9 units or more; Derivatives thereof
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Polymers & Plastics (AREA)
- Materials Engineering (AREA)
- Biochemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US64784105P | 2005-01-28 | 2005-01-28 | |
| US60/647,841 | 2005-01-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU2007133709A true RU2007133709A (ru) | 2009-03-20 |
Family
ID=36777776
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2007133709/04A RU2007133709A (ru) | 2005-01-28 | 2006-01-27 | Производные в-циклодекстрина в качестве антибактериальных агентов |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US7737132B2 (https=) |
| EP (1) | EP1846006A4 (https=) |
| JP (1) | JP2008528761A (https=) |
| KR (1) | KR20070101347A (https=) |
| CN (1) | CN101151037A (https=) |
| AU (1) | AU2006211173A1 (https=) |
| CA (1) | CA2596026A1 (https=) |
| IL (1) | IL184844A0 (https=) |
| MX (1) | MX2007010129A (https=) |
| RU (1) | RU2007133709A (https=) |
| WO (1) | WO2006083678A2 (https=) |
| ZA (1) | ZA200706191B (https=) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1735326A4 (en) * | 2004-01-29 | 2011-04-20 | Pinnacle Pharmaceuticals | BETA-CYCLODEXTRIN DERIVATIVES AND THEIR USE AGAINST LETHAL ANTHRAX TOXIN |
| WO2006075580A1 (ja) * | 2005-01-13 | 2006-07-20 | National University Corporation Nagoya Institute Of Technology | 菌体膜傷害性・抗菌性物質とその利用方法 |
| CN101151037A (zh) * | 2005-01-28 | 2008-03-26 | 平纳克尔医药股份有限公司 | 作为抗菌剂的β-环糊精衍生物 |
| CA2662142A1 (en) * | 2006-08-30 | 2008-09-04 | Pace University | Antimicrobial compositions |
| WO2009058327A1 (en) * | 2007-10-30 | 2009-05-07 | Pinnacle Pharmaceuticals, Inc. | Cyclodextrin derivatives as potentiators for antibiotics |
| JP5364923B2 (ja) * | 2009-01-28 | 2013-12-11 | 学校法人福岡大学 | 多機能性シクロデキストリン誘導体、その包接化合物およびそれらの製造方法。 |
| WO2012151445A1 (en) * | 2011-05-03 | 2012-11-08 | Innovative Biologics, Inc. | DERIVATIVES OF α-, β- AND γ-CYCLODEXTRIN AND THEIR USE AS ANTI-INFECTIVES |
| GB201114459D0 (en) | 2011-08-22 | 2011-10-05 | Isis Innovation | Anti-bacterial compounds |
| EP2690105A1 (en) * | 2012-07-24 | 2014-01-29 | Centre National De La Recherche Scientifique | Mannose derivatives, a process for preparing the same and their uses as a drug |
| JP6249208B2 (ja) * | 2012-10-31 | 2017-12-20 | 国立大学法人 名古屋工業大学 | 糖誘導体及びそれを用いた抗菌剤 |
| CN103497275B (zh) * | 2013-08-09 | 2015-12-23 | 华北电力大学（保定） | 一种抗菌、抗病毒胍盐星形聚合物及其制备方法和应用 |
| JP6624422B2 (ja) * | 2014-07-25 | 2019-12-25 | 国立大学法人 名古屋工業大学 | 糖誘導体またはその塩、それらを用いた抗菌剤または抗菌活性増強剤、およびこれらを合成する試薬、試薬を用いたこれらの製造方法 |
| CN106734046A (zh) * | 2015-11-20 | 2017-05-31 | 南京科技职业学院 | 一种焦化污泥无害化处理方法 |
| EP3514182A4 (en) | 2016-09-13 | 2020-06-24 | Nagoya Institute of Technology | Sugar derivative or salt thereof, and antibacterial agent or antibacterial activity enhancer using same |
| WO2018127819A1 (en) | 2017-01-03 | 2018-07-12 | The University Of North Carolina At Chapel Hill | Nitric oxide-releasing alginates as biodegradable antibacterial scaffolds and methods pertaining thereto |
| JP7403152B2 (ja) | 2017-03-28 | 2023-12-22 | ザ ユニバーシティ オブ ノース カロライナ アット チャペル ヒル | 生分解可能な抗菌性スキャフォールドとしての一酸化窒素放出性ポリアミノグリコシドおよびそれに関する方法背景 |
| KR101967326B1 (ko) * | 2017-10-30 | 2019-08-13 | 한남대학교 산학협력단 | 양이온성 사이클로덱스트린 유도체 및 이를 이용한 약물전달 시스템 |
| EP3710514B1 (en) | 2017-11-15 | 2023-06-07 | The University of North Carolina at Chapel Hill | Nitric oxide-releasing hyperbranched compounds as antibacterial scaffolds and methods pertaining thereto |
| CA3091458A1 (en) * | 2018-03-06 | 2019-09-12 | The University Of North Carolina At Chapel Hill | Nitric oxide-releasing cyclodextrins as biodegradable antibacterial scaffolds and methods pertaining thereto |
| CN113383019B (zh) | 2018-12-28 | 2023-11-17 | 北卡罗来纳大学教堂山分校 | 一氧化氮释放型抗菌聚合物和由其制成的支架和其相关方法 |
| TWI774079B (zh) * | 2020-10-05 | 2022-08-11 | 逢興生物科技股份有限公司 | 環糊精用於製造抑制口腔細菌生長的組合物的用途 |
| CN112516003A (zh) * | 2020-12-18 | 2021-03-19 | 上海杜可生物科技有限公司 | 环糊精用于抑制口腔细菌生长的组合物的用途 |
| US11856953B2 (en) | 2021-03-11 | 2024-01-02 | Nano And Advanced Materials Institute Limited | Launderable bactericidal and virucidal fabric finish |
| CN116284506B (zh) * | 2023-03-22 | 2023-12-08 | 江南大学 | 一种γ-环糊精-香叶醇衍生物及其制备方法与应用 |
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| US576017A (en) * | 1897-01-26 | Game-counter | ||
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| DE2425663A1 (de) | 1974-05-28 | 1975-12-04 | Tanabe Seiyaku Co | Cyclodextrinderivate sowie verfahren zu ihrer herstellung |
| JPS51142088A (en) | 1975-05-29 | 1976-12-07 | Tanabe Seiyaku Co Ltd | Aminocyclodextrin derivatives and their prepapation. |
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| DE19520967A1 (de) | 1995-06-08 | 1996-12-12 | Consortium Elektrochem Ind | Textiles Material oder Leder, welches mit Cyclodextrinderivaten mit mindestens einem stickstoffhaltigen Heterozyklus ausgerüstet ist |
| FR2736056B1 (fr) * | 1995-06-29 | 1997-08-08 | Commissariat Energie Atomique | Derives de cyclodextrines, leur preparation et leur utilisation pour incorporer des molecules hydrophobes dans des systemes de tensioactifs organises |
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| FR2767834B1 (fr) * | 1997-08-29 | 1999-12-03 | Inst Francais Du Petrole | Mono et di-derives de cyclodextrines, leurs synthese et purification et leur utilisation en support |
| US6180356B1 (en) * | 1998-03-06 | 2001-01-30 | The Research Foundation Of State University Of Ny | Membrane pore inhibiting agents for treating infection |
| FR2776666B1 (fr) * | 1998-03-31 | 2002-09-06 | Commissariat Energie Atomique | Complexes d'inclusion dans des cyclodextrines d'isothiocyanates organiques, en particulier bacteriostatiques, bactericides et/ou fongicides ou de leurs precurseurs naturels, et leur preparation |
| FR2792942B1 (fr) * | 1999-04-29 | 2001-06-08 | Commissariat Energie Atomique | Cyclodextrines amphiphiles, leur preparation et leur utilisation pour solubiliser des systemes organises et incorporer des molecules hydrophobes |
| TWI242015B (en) | 1999-11-29 | 2005-10-21 | Akzo Nobel Nv | 6-mercapto-cyclodextrin derivatives: reversal agents for drug-induced neuromuscular block |
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| SG114468A1 (en) | 2000-06-23 | 2005-09-28 | Univ Singapore | Separation materials for chromatography and electrophoresis applications comprising cyclodextrins cross-linked and chemically bonded to a support via urethane linkages |
| AU2002246302A1 (en) | 2001-03-23 | 2002-10-08 | University College Dublin | Macrocyclic oligosaccharide derivatives which form manoscale assemblies |
| US6632748B2 (en) * | 2001-03-27 | 2003-10-14 | Samsung Electronics Co., Ltd. | Composition for preparing substances having nano-pores |
| EP1245628B1 (en) * | 2001-03-27 | 2008-08-27 | Samsung Electronics Co., Ltd. | Composition for preparing substances having nano-pores |
| FR2843397B1 (fr) | 2002-08-06 | 2004-10-15 | Chelator | Nouveaux derives de cyclodextrines, leur procede de preparation et leurs applications |
| KR100533538B1 (ko) * | 2002-12-03 | 2005-12-05 | 삼성전자주식회사 | 새로운 기공형성물질을 포함하는 다공성 층간 절연막을형성하기 위한 조성물 |
| WO2004085487A1 (ja) | 2003-03-27 | 2004-10-07 | Yokohama Tlo Company, Ltd. | 新規シクロデキストリン誘導体 |
| FR2852959B1 (fr) | 2003-03-28 | 2008-02-15 | Centre Nat Rech Scient | Nouveaux derives de cyclodextrines, leur procede de preparation et leur utilisation notamment pour solubilisation de substances pharmacologiquement actives |
| US20050059634A1 (en) * | 2003-07-28 | 2005-03-17 | Venton Duane L. | Per-6-substituted-per-6-deoxy-cyclodextrins, and use of the same to inhibit soluble beta-amyloid-peptide derived oligomers and to treat alzheimer's and related diseases |
| FR2861396B1 (fr) | 2003-10-24 | 2005-12-16 | Commissariat Energie Atomique | Derives amphiphiles de cyclodextrines,leur procede de preparation et leurs utilisations |
| EP1735326A4 (en) * | 2004-01-29 | 2011-04-20 | Pinnacle Pharmaceuticals | BETA-CYCLODEXTRIN DERIVATIVES AND THEIR USE AGAINST LETHAL ANTHRAX TOXIN |
| JP2005290066A (ja) | 2004-03-31 | 2005-10-20 | Nihon Hels Industry Corp | シクロデキストリンポリマーおよびこれを利用した水の汚染度の測定方法 |
| EP1817348B1 (en) | 2004-09-10 | 2011-06-22 | National Center for Scientific Research "Demokritos" Neapoleos & | Per-6-guanidino-, -aminoalkylamino-and -guanidino-alkylamino-cyclodextrins, methods of their synthesis and their use for the compaction of dna and intracellular delivery |
| FR2878853B1 (fr) | 2004-12-07 | 2007-03-16 | Biocydex Soc Par Actions Simpl | Procede d'obtention d'un complexe fluorescent, complexe obtenu et utilisation |
| WO2006075580A1 (ja) | 2005-01-13 | 2006-07-20 | National University Corporation Nagoya Institute Of Technology | 菌体膜傷害性・抗菌性物質とその利用方法 |
| CN101151037A (zh) * | 2005-01-28 | 2008-03-26 | 平纳克尔医药股份有限公司 | 作为抗菌剂的β-环糊精衍生物 |
| WO2007009265A1 (en) * | 2005-07-22 | 2007-01-25 | The Governors Of The University Of Alberta Tec Edmonton | NOVEL β-CYCLODEXTRIN-BASED MOLECULES AND DRUG DELIVERY COMPOSITIONS |
-
2006
- 2006-01-27 CN CNA2006800101557A patent/CN101151037A/zh active Pending
- 2006-01-27 US US11/342,339 patent/US7737132B2/en not_active Expired - Fee Related
- 2006-01-27 MX MX2007010129A patent/MX2007010129A/es unknown
- 2006-01-27 RU RU2007133709/04A patent/RU2007133709A/ru not_active Application Discontinuation
- 2006-01-27 CA CA002596026A patent/CA2596026A1/en not_active Abandoned
- 2006-01-27 JP JP2007553231A patent/JP2008528761A/ja active Pending
- 2006-01-27 KR KR1020077019399A patent/KR20070101347A/ko not_active Withdrawn
- 2006-01-27 AU AU2006211173A patent/AU2006211173A1/en not_active Abandoned
- 2006-01-27 EP EP06733927A patent/EP1846006A4/en not_active Withdrawn
- 2006-01-27 WO PCT/US2006/002801 patent/WO2006083678A2/en not_active Ceased
-
2007
- 2007-07-26 ZA ZA200706191A patent/ZA200706191B/xx unknown
- 2007-07-26 IL IL184844A patent/IL184844A0/en unknown
-
2010
- 2010-05-03 US US12/772,740 patent/US20110071108A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2006083678A2 (en) | 2006-08-10 |
| WO2006083678A3 (en) | 2006-12-14 |
| KR20070101347A (ko) | 2007-10-16 |
| US20060199785A1 (en) | 2006-09-07 |
| US7737132B2 (en) | 2010-06-15 |
| IL184844A0 (en) | 2008-06-05 |
| EP1846006A2 (en) | 2007-10-24 |
| ZA200706191B (en) | 2010-05-26 |
| MX2007010129A (es) | 2007-11-16 |
| AU2006211173A1 (en) | 2006-08-10 |
| JP2008528761A (ja) | 2008-07-31 |
| EP1846006A4 (en) | 2011-04-20 |
| US20110071108A1 (en) | 2011-03-24 |
| CA2596026A1 (en) | 2006-08-10 |
| CN101151037A (zh) | 2008-03-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA92 | Acknowledgement of application withdrawn (lack of supplementary materials submitted) |
Effective date: 20100415 |