RU2007118691A - Применение 4-трифторметилфениламида (z)-2-циано-3-гидрокси-бут-2-еновой кислоты для лечения воспалительных заболеваний кишечника - Google Patents
Применение 4-трифторметилфениламида (z)-2-циано-3-гидрокси-бут-2-еновой кислоты для лечения воспалительных заболеваний кишечника Download PDFInfo
- Publication number
- RU2007118691A RU2007118691A RU2007118691/14A RU2007118691A RU2007118691A RU 2007118691 A RU2007118691 A RU 2007118691A RU 2007118691/14 A RU2007118691/14 A RU 2007118691/14A RU 2007118691 A RU2007118691 A RU 2007118691A RU 2007118691 A RU2007118691 A RU 2007118691A
- Authority
- RU
- Russia
- Prior art keywords
- treatment
- trifluoromethylphenylamide
- intestine
- cyano
- hydroxy
- Prior art date
Links
- ODGIMMLDVSWADK-UHFFFAOYSA-N 4-trifluoromethylaniline Chemical compound NC1=CC=C(C(F)(F)F)C=C1 ODGIMMLDVSWADK-UHFFFAOYSA-N 0.000 title 1
- 239000002253 acid Substances 0.000 title 1
- 208000027866 inflammatory disease Diseases 0.000 title 1
- 210000000936 intestine Anatomy 0.000 title 1
- 208000022559 Inflammatory bowel disease Diseases 0.000 claims 5
- 206010009900 Colitis ulcerative Diseases 0.000 claims 1
- 208000011231 Crohn disease Diseases 0.000 claims 1
- 206010058838 Enterocolitis infectious Diseases 0.000 claims 1
- 201000006704 Ulcerative Colitis Diseases 0.000 claims 1
- 206010009887 colitis Diseases 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 208000027139 infectious colitis Diseases 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/275—Nitriles; Isonitriles
- A61K31/277—Nitriles; Isonitriles having a ring, e.g. verapamil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pain & Pain Management (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Rheumatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US62025504P | 2004-10-19 | 2004-10-19 | |
| US60/620,255 | 2004-10-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU2007118691A true RU2007118691A (ru) | 2008-11-27 |
Family
ID=35636963
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2007118691/14A RU2007118691A (ru) | 2004-10-19 | 2005-10-18 | Применение 4-трифторметилфениламида (z)-2-циано-3-гидрокси-бут-2-еновой кислоты для лечения воспалительных заболеваний кишечника |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20070197643A1 (enExample) |
| EP (1) | EP1804782A1 (enExample) |
| JP (1) | JP2008517059A (enExample) |
| KR (1) | KR20070065888A (enExample) |
| CN (1) | CN101043883A (enExample) |
| AU (1) | AU2005295511A1 (enExample) |
| BR (1) | BRPI0518205A (enExample) |
| CA (1) | CA2584655A1 (enExample) |
| IL (1) | IL182591A0 (enExample) |
| MX (1) | MX2007004265A (enExample) |
| RU (1) | RU2007118691A (enExample) |
| SG (1) | SG142305A1 (enExample) |
| WO (1) | WO2006044741A1 (enExample) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2006268238A1 (en) | 2005-07-11 | 2007-01-18 | Medtronic Ablation Frontiers Llc | Low power tissue ablation system |
| ES2319596B1 (es) | 2006-12-22 | 2010-02-08 | Laboratorios Almirall S.A. | Nuevos derivados de los acidos amino-nicotinico y amino-isonicotinico. |
| EP2100881A1 (en) | 2008-03-13 | 2009-09-16 | Laboratorios Almirall, S.A. | Pyrimidyl- or pyridinylaminobenzoic acid derivatives |
| UY31272A1 (es) | 2007-08-10 | 2009-01-30 | Almirall Lab | Nuevos derivados de ácido azabifenilaminobenzoico |
| EP2135610A1 (en) | 2008-06-20 | 2009-12-23 | Laboratorios Almirall, S.A. | Combination comprising DHODH inhibitors and methotrexate |
| EP2230232A1 (en) | 2009-03-13 | 2010-09-22 | Almirall, S.A. | Addition salts of tromethamine with azabiphenylaminobenzoic acid derivatives as DHODH inhibitors |
| EP2228367A1 (en) | 2009-03-13 | 2010-09-15 | Almirall, S.A. | Addition salts of amines containing hydroxyl and/or carboxylic groups with amino nicotinic acid derivatives as DHODH inhibitors |
| EP2239256A1 (en) | 2009-03-13 | 2010-10-13 | Almirall, S.A. | Sodium salt of 5-cyclopropyl-2-{[2-(2,6-difluorophenyl)pyrimidin-5-yl]amino}benzoic acid as DHODH inhibitor |
| EP2277515A1 (en) * | 2009-07-10 | 2011-01-26 | Sanofi-Aventis | Use of the combination of teriflunomide and interferon beta for treating multiple sclerosis |
| HRP20170904T1 (hr) * | 2009-09-18 | 2017-09-08 | Sanofi | Formulacije tableta (4'-trifluormetilfenil)-amida (z)-2-cijano-3-hidroksi-but-2-enske kiseline s poboljšanom stabilnošću |
| EP2314577A1 (en) | 2009-10-16 | 2011-04-27 | Almirall, S.A. | Process for manufacturing 2-[(3,5-difluoro-3'-methoxy-1,1'-biphenyl-4-yl)amino]nicotinic acid |
| US8686048B2 (en) | 2010-05-06 | 2014-04-01 | Rhizen Pharmaceuticals Sa | Immunomodulator and anti-inflammatory compounds |
| WO2012109329A2 (en) | 2011-02-08 | 2012-08-16 | Children's Medical Center Corporation | Methods for treatment of melanoma |
| JOP20190207A1 (ar) * | 2017-03-14 | 2019-09-10 | Actelion Pharmaceuticals Ltd | تركيبة صيدلانية تشتمل على بونيسيمود |
| CN116725998A (zh) * | 2023-07-20 | 2023-09-12 | 中国科学技术大学 | 特立氟胺在抑制nlrp3炎症小体活化中的应用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19547648A1 (de) * | 1995-12-20 | 1997-06-26 | Hoechst Ag | Zubereitung, enthaltend High Density Lipoproteine und Crotonsäureamidderivate |
| CA2328962A1 (en) * | 1998-04-17 | 1999-10-28 | Parker Hughes Institute | Btk inhibitors and methods for their identification and use |
| GB0005345D0 (en) * | 2000-03-06 | 2000-04-26 | Mathilda & Terence Kennedy Ins | Methods of treating sepsis septic shock and inflammation |
| CN1507354A (zh) * | 2001-03-02 | 2004-06-23 | ͨ��ҽ�ƹ�˾ | 通过给予整合蛋白αvβ3拮抗剂并与其它预防或治疗药剂配合来预防或者治疗炎性疾病或自身免疫疾病的方法 |
| ATE396719T1 (de) * | 2001-04-05 | 2008-06-15 | Aventis Pharma Inc | Verwendung von (z)-2-cyano-3-hydroxy-but-2- ensäure-(4'-trifluoromethylphenyl)-amid zur behandlung der multiplen sklerose |
| JP2005538165A (ja) * | 2002-09-06 | 2005-12-15 | シェボ ビオテック アクティエン ゲゼルシャフト | 解糖酵素及び／又はアミノ基転移酵素錯体調節用化合物 |
-
2005
- 2005-10-18 CN CNA2005800357982A patent/CN101043883A/zh active Pending
- 2005-10-18 MX MX2007004265A patent/MX2007004265A/es not_active Application Discontinuation
- 2005-10-18 WO PCT/US2005/037161 patent/WO2006044741A1/en not_active Ceased
- 2005-10-18 JP JP2007537944A patent/JP2008517059A/ja not_active Abandoned
- 2005-10-18 SG SG200802858-1A patent/SG142305A1/en unknown
- 2005-10-18 BR BRPI0518205-0A patent/BRPI0518205A/pt not_active IP Right Cessation
- 2005-10-18 AU AU2005295511A patent/AU2005295511A1/en not_active Abandoned
- 2005-10-18 RU RU2007118691/14A patent/RU2007118691A/ru not_active Application Discontinuation
- 2005-10-18 CA CA002584655A patent/CA2584655A1/en not_active Abandoned
- 2005-10-18 EP EP05812243A patent/EP1804782A1/en not_active Ceased
- 2005-10-18 KR KR1020077008909A patent/KR20070065888A/ko not_active Withdrawn
-
2007
- 2007-03-29 US US11/693,358 patent/US20070197643A1/en not_active Abandoned
- 2007-04-16 IL IL182591A patent/IL182591A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2006044741A1 (en) | 2006-04-27 |
| CA2584655A1 (en) | 2006-04-27 |
| IL182591A0 (en) | 2007-09-20 |
| US20070197643A1 (en) | 2007-08-23 |
| BRPI0518205A (pt) | 2008-11-04 |
| CN101043883A (zh) | 2007-09-26 |
| SG142305A1 (en) | 2008-05-28 |
| EP1804782A1 (en) | 2007-07-11 |
| KR20070065888A (ko) | 2007-06-25 |
| JP2008517059A (ja) | 2008-05-22 |
| MX2007004265A (es) | 2008-03-04 |
| AU2005295511A1 (en) | 2006-04-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA92 | Acknowledgement of application withdrawn (lack of supplementary materials submitted) |
Effective date: 20090807 |