RU2006131454A - Новые производные мочевины и их медицинское применение - Google Patents

Новые производные мочевины и их медицинское применение Download PDF

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RU2006131454A
RU2006131454A RU2006131454/04A RU2006131454A RU2006131454A RU 2006131454 A RU2006131454 A RU 2006131454A RU 2006131454/04 A RU2006131454/04 A RU 2006131454/04A RU 2006131454 A RU2006131454 A RU 2006131454A RU 2006131454 A RU2006131454 A RU 2006131454A
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Russia
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phenyl
hydroxy
hydrogen
alkyl
urea
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RU2006131454/04A
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English (en)
Russian (ru)
Inventor
Бь рне Х. ДАХЛЬ (DK)
Бьярне Х. ДАХЛЬ
Дан ПЕТЕРС (DK)
Дан ПЕТЕРС
Гуннар М. ОЛЬСЕН (DK)
Гуннар М. Ольсен
Тино Дюхринг ЕРГЕНСЕН (DK)
Тино Дюхринг ЕРГЕНСЕН
Даниель Б. ТИММЕРМАН (DK)
Даниель Б. ТИММЕРМАН
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Ньюросерч А/С (DK)
Ньюросерч А/С
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Publication of RU2006131454A publication Critical patent/RU2006131454A/ru

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    • C07—ORGANIC CHEMISTRY
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    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C275/30—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by halogen atoms, or by nitro or nitroso groups
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C275/32—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by singly-bound oxygen atoms
    • C07C275/34—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by singly-bound oxygen atoms having nitrogen atoms of urea groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C275/40—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by nitrogen atoms not being part of nitro or nitroso groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
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    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/36—Oxygen or sulfur atoms
    • C07D207/40—2,5-Pyrrolidine-diones

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  • Health & Medical Sciences (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Endocrinology (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Reproductive Health (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Psychology (AREA)
  • Obesity (AREA)
  • Pulmonology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Vascular Medicine (AREA)
  • Nutrition Science (AREA)
  • Child & Adolescent Psychology (AREA)
  • Anesthesiology (AREA)
  • Urology & Nephrology (AREA)
  • Dermatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Orthopedic Medicine & Surgery (AREA)
RU2006131454/04A 2004-03-29 2005-03-16 Новые производные мочевины и их медицинское применение RU2006131454A (ru)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DKPA200400498 2004-03-29
DKPA200400498 2004-03-29
US55769804P 2004-03-31 2004-03-31
US60/557,698 2004-03-31

Publications (1)

Publication Number Publication Date
RU2006131454A true RU2006131454A (ru) 2008-05-10

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RU2006131454/04A RU2006131454A (ru) 2004-03-29 2005-03-16 Новые производные мочевины и их медицинское применение

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Country Link
US (1) US20070142450A1 (enExample)
EP (1) EP1732883A1 (enExample)
JP (1) JP2007530635A (enExample)
CN (1) CN1926098A (enExample)
AU (1) AU2005225559A1 (enExample)
BR (1) BRPI0507296A (enExample)
CA (1) CA2561639A1 (enExample)
RU (1) RU2006131454A (enExample)
WO (1) WO2005092843A1 (enExample)

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RU2627271C2 (ru) * 2011-11-10 2017-08-04 Аллерган, Инк. Производные арилмочевины в качестве модуляторов n-формилпептидного-1 рецептора (fprl-1)

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EP2255848A3 (en) * 2006-09-04 2011-04-06 NeuroSearch AS Pharmaceutical combinations of a nicotine receptor modulator and a cognitive enhancer
WO2010130063A1 (zh) * 2009-05-12 2010-11-18 Han Mei 具有促进干細胞增殖作用的小分子化合物及其用途
WO2012029994A1 (en) 2010-09-02 2012-03-08 Kyoto University Pharmaceutical composition for prevention and treatment of amyotrophic lateral sclerosis
US20130310419A1 (en) 2011-02-03 2013-11-21 Lupin Limited Pyrrole derivatives used as modulators of alpha7 nachr
AU2012221800B2 (en) 2011-02-23 2016-10-27 Lupin Limited Heteroaryl derivatives as alpha7 nAChR modulators
KR20140025395A (ko) 2011-03-31 2014-03-04 루핀 리미티드 알츠하이머병 및 파킨슨병을 포함하는 신경병성 장애 치료용 니코틴성 아세틸콜린 수용체 조절인자로서의 피롤 유도체
KR20140027939A (ko) 2011-06-30 2014-03-07 도레이 카부시키가이샤 지양제
EP2729455B1 (en) 2011-07-05 2016-09-14 Lupin Limited Biaryl derivatives as nachr modulators
CN103172543B (zh) * 2011-12-21 2016-02-10 中国科学院上海药物研究所 一种脲类化合物、制备方法及其用途
EP2822946A1 (en) 2012-03-06 2015-01-14 Lupin Limited Thiazole derivatives as alpha 7 nachr modulators
EP2945936A1 (en) 2012-11-12 2015-11-25 Lupin Limited Thiazole derivatives as alpha 7 nachr modulators
US9617211B2 (en) 2013-01-16 2017-04-11 Lupin Limited Pyrrole derivatives as alpha 7 nAChR modulators
CA2892682A1 (en) 2013-03-13 2014-09-18 Lupin Limited Pyrrole derivatives as alpha 7 nachr modulators
TW201446243A (zh) 2013-06-03 2014-12-16 Lupin Ltd 4-(5-(4-氯苯基)-2-(2-環丙基乙醯基)-1,4-二甲基-1氫-吡咯-3-基)苯磺醯胺作為α7尼古丁乙醯膽鹼受體調節劑
CA2913987A1 (en) 2013-06-17 2014-12-24 Lupin Limited Pyrrole derivatives as alpha 7 nachr modulators

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2627271C2 (ru) * 2011-11-10 2017-08-04 Аллерган, Инк. Производные арилмочевины в качестве модуляторов n-формилпептидного-1 рецептора (fprl-1)

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AU2005225559A1 (en) 2005-10-06
BRPI0507296A (pt) 2007-07-03
CA2561639A1 (en) 2005-10-06
CN1926098A (zh) 2007-03-07
US20070142450A1 (en) 2007-06-21
JP2007530635A (ja) 2007-11-01
WO2005092843A1 (en) 2005-10-06
EP1732883A1 (en) 2006-12-20

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