CN1926098A - 新的脲衍生物及其医药应用 - Google Patents

新的脲衍生物及其医药应用 Download PDF

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Publication number
CN1926098A
CN1926098A CNA200580006364XA CN200580006364A CN1926098A CN 1926098 A CN1926098 A CN 1926098A CN A200580006364X A CNA200580006364X A CN A200580006364XA CN 200580006364 A CN200580006364 A CN 200580006364A CN 1926098 A CN1926098 A CN 1926098A
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phenyl
hydroxyl
halogen
expression hydrogen
nitro
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CNA200580006364XA
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Chinese (zh)
Inventor
B·H·达尔
D·皮特斯
G·M·奥尔森
T·D·卓根森
D·B·逖米尔曼
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NTG Nordic Transport Group AS
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Neurosearch AS
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Publication of CN1926098A publication Critical patent/CN1926098A/zh
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    • C07C275/30—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by halogen atoms, or by nitro or nitroso groups
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  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
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  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Pain & Pain Management (AREA)
  • Endocrinology (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Reproductive Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Obesity (AREA)
  • Gynecology & Obstetrics (AREA)
  • Hematology (AREA)
  • Psychology (AREA)
  • Anesthesiology (AREA)
  • Nutrition Science (AREA)
  • Child & Adolescent Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pregnancy & Childbirth (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
CNA200580006364XA 2004-03-29 2005-03-16 新的脲衍生物及其医药应用 Pending CN1926098A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA200400498 2004-03-29
DKPA200400498 2004-03-29
US60/557,698 2004-03-31

Publications (1)

Publication Number Publication Date
CN1926098A true CN1926098A (zh) 2007-03-07

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ID=37818161

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CNA200580006364XA Pending CN1926098A (zh) 2004-03-29 2005-03-16 新的脲衍生物及其医药应用

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US (1) US20070142450A1 (enExample)
EP (1) EP1732883A1 (enExample)
JP (1) JP2007530635A (enExample)
CN (1) CN1926098A (enExample)
AU (1) AU2005225559A1 (enExample)
BR (1) BRPI0507296A (enExample)
CA (1) CA2561639A1 (enExample)
RU (1) RU2006131454A (enExample)
WO (1) WO2005092843A1 (enExample)

Cited By (1)

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CN103172543A (zh) * 2011-12-21 2013-06-26 中国科学院上海药物研究所 一种脲类化合物、制备方法及其用途

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WO2006089871A2 (en) * 2005-02-23 2006-08-31 Neurosearch A/S Diphenylurea derivatives useful as erg channel openers for the treatment of cardiac arrhythmias
EP2255848A3 (en) * 2006-09-04 2011-04-06 NeuroSearch AS Pharmaceutical combinations of a nicotine receptor modulator and a cognitive enhancer
WO2010130063A1 (zh) * 2009-05-12 2010-11-18 Han Mei 具有促进干細胞增殖作用的小分子化合物及其用途
WO2012029994A1 (en) 2010-09-02 2012-03-08 Kyoto University Pharmaceutical composition for prevention and treatment of amyotrophic lateral sclerosis
AU2012213086B2 (en) 2011-02-03 2016-05-05 Lupin Limited Pyrrole derivatives used as modulators of alpha7 nAChR
KR20140026378A (ko) 2011-02-23 2014-03-05 루핀 리미티드 알파 7 ｎａｃｈｒ 조절자로서 헤테로아릴 유도체
AU2012235779B2 (en) 2011-03-31 2017-03-02 Lupin Limited Pyrrole derivatives as nicotinic acetylcholine receptor modulators for use in the treatment of neurodegenerative disorders such as Alzheimer's and Parkinson's disease
RU2014103098A (ru) 2011-06-30 2015-08-10 Торэй Индастриз, Инк. Противозудный агент
US8946432B2 (en) 2011-07-05 2015-02-03 Lupin Limited Biaryl derivatives as nAChR modulators
US8541577B2 (en) * 2011-11-10 2013-09-24 Allergan, Inc. Aryl urea derivatives as N-formyl peptide receptors like-1 (FPRL-1) receptor modulators
EP2822946A1 (en) 2012-03-06 2015-01-14 Lupin Limited Thiazole derivatives as alpha 7 nachr modulators
US20150299178A1 (en) 2012-11-12 2015-10-22 Lupin Limited Thiazole Derivatives as Alpha 7 NACHR Modulators
EP2945941B1 (en) 2013-01-16 2016-12-07 Lupin Limited Pyrrole derivatives as alpha 7 nachr modulators
US9617210B2 (en) 2013-03-13 2017-04-11 Lupin Limited Pyrrole derivatives as alpha 7 NACHR modulators
TW201446243A (zh) 2013-06-03 2014-12-16 Lupin Ltd 4-(5-(4-氯苯基)-2-(2-環丙基乙醯基)-1,4-二甲基-1氫-吡咯-3-基)苯磺醯胺作為α7尼古丁乙醯膽鹼受體調節劑
WO2014203150A1 (en) 2013-06-17 2014-12-24 Lupin Limited Pyrrole derivatives as alpha 7 nachr modulators

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DE3237479A1 (de) * 1982-10-09 1984-04-12 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von substituierten tetrahydropyrimidinonderivaten
DK41193D0 (da) * 1993-04-07 1993-04-07 Neurosearch As Ionkanalaabnere
DE69432984T2 (de) * 1993-05-27 2004-05-27 Cenes Ltd. Therapeutische substituierte guanidine
EP0809492A4 (en) * 1995-02-17 2007-01-24 Smithkline Beecham Corp IL-8 RECEPTOR ANTAGONISTS
AU2962297A (en) * 1996-05-24 1998-01-05 Neurosearch A/S Phenyl derivatives useful as blockers of chloride channels
CA2315715C (en) * 1997-12-22 2010-06-22 Bayer Corporation Inhibition of p38 kinase using symmetrical and unsymmetrical diphenyl ureas
WO2000001349A2 (en) * 1998-07-01 2000-01-13 The Trustees Of The University Of Pennsylvania Cavity induced allosteric modification of intermolecular interactions and methods of identifying compounds that effect the same
US20040063742A1 (en) * 2001-02-15 2004-04-01 Dan Peters Treatment of parkinson's disease by the combined action of a compound with neurotrophic activity and a compound enhancing the dopamine activity
US20030236287A1 (en) 2002-05-03 2003-12-25 Piotrowski David W. Positive allosteric modulators of the nicotinic acetylcholine receptor

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103172543A (zh) * 2011-12-21 2013-06-26 中国科学院上海药物研究所 一种脲类化合物、制备方法及其用途
WO2013091285A1 (zh) * 2011-12-21 2013-06-27 中国科学院上海药物研究所 一种脲类化合物、制备方法及其用途
CN103172543B (zh) * 2011-12-21 2016-02-10 中国科学院上海药物研究所 一种脲类化合物、制备方法及其用途

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CA2561639A1 (en) 2005-10-06
RU2006131454A (ru) 2008-05-10
WO2005092843A1 (en) 2005-10-06
BRPI0507296A (pt) 2007-07-03
JP2007530635A (ja) 2007-11-01
AU2005225559A1 (en) 2005-10-06
US20070142450A1 (en) 2007-06-21

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