RU2004136999A - Способы лечения болевых расстройств желудочно-кишечной и мочеполовой систем, использующие венлфаксин и его производные - Google Patents
Способы лечения болевых расстройств желудочно-кишечной и мочеполовой систем, использующие венлфаксин и его производные Download PDFInfo
- Publication number
- RU2004136999A RU2004136999A RU2004136999/14A RU2004136999A RU2004136999A RU 2004136999 A RU2004136999 A RU 2004136999A RU 2004136999/14 A RU2004136999/14 A RU 2004136999/14A RU 2004136999 A RU2004136999 A RU 2004136999A RU 2004136999 A RU2004136999 A RU 2004136999A
- Authority
- RU
- Russia
- Prior art keywords
- carbon atoms
- functional gastrointestinal
- alkyl containing
- day
- alkyl
- Prior art date
Links
- 238000000034 method Methods 0.000 title claims 19
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title claims 5
- 230000002496 gastric effect Effects 0.000 title claims 3
- 208000002193 Pain Diseases 0.000 title claims 2
- 125000004432 carbon atom Chemical group C* 0.000 claims 20
- 125000000217 alkyl group Chemical group 0.000 claims 11
- 206010000059 abdominal discomfort Diseases 0.000 claims 7
- 229910052739 hydrogen Inorganic materials 0.000 claims 7
- 239000001257 hydrogen Substances 0.000 claims 7
- 150000001875 compounds Chemical class 0.000 claims 5
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 4
- 241000124008 Mammalia Species 0.000 claims 4
- 150000003839 salts Chemical class 0.000 claims 4
- 125000003545 alkoxy group Chemical group 0.000 claims 3
- 208000035475 disorder Diseases 0.000 claims 3
- 150000002431 hydrogen Chemical class 0.000 claims 3
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 claims 3
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 claims 2
- 206010008479 Chest Pain Diseases 0.000 claims 2
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 claims 2
- 208000025609 Urogenital disease Diseases 0.000 claims 2
- 125000004423 acyloxy group Chemical group 0.000 claims 2
- 208000003770 biliary dyskinesia Diseases 0.000 claims 2
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 claims 2
- 229910052794 bromium Inorganic materials 0.000 claims 2
- 229910052801 chlorine Inorganic materials 0.000 claims 2
- 239000000460 chlorine Substances 0.000 claims 2
- HPXRVTGHNJAIIH-UHFFFAOYSA-N cyclohexanol Chemical compound OC1CCCCC1 HPXRVTGHNJAIIH-UHFFFAOYSA-N 0.000 claims 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 2
- 125000004203 4-hydroxyphenyl group Chemical group [H]OC1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 1
- 208000000094 Chronic Pain Diseases 0.000 claims 1
- 206010020751 Hypersensitivity Diseases 0.000 claims 1
- 208000005615 Interstitial Cystitis Diseases 0.000 claims 1
- 208000009505 Sphincter of Oddi Dysfunction Diseases 0.000 claims 1
- 125000003282 alkyl amino group Chemical group 0.000 claims 1
- 125000004414 alkyl thio group Chemical group 0.000 claims 1
- 230000000747 cardiac effect Effects 0.000 claims 1
- 125000004093 cyano group Chemical group *C#N 0.000 claims 1
- 125000004663 dialkyl amino group Chemical group 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 201000006549 dyspepsia Diseases 0.000 claims 1
- 210000003238 esophagus Anatomy 0.000 claims 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims 1
- 125000002485 formyl group Chemical group [H]C(*)=O 0.000 claims 1
- 239000012634 fragment Substances 0.000 claims 1
- 229910052736 halogen Inorganic materials 0.000 claims 1
- 150000002367 halogens Chemical class 0.000 claims 1
- 208000002551 irritable bowel syndrome Diseases 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- -1 methylenedioxy Chemical group 0.000 claims 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 claims 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims 1
- 230000011514 reflex Effects 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/275—Nitriles; Isonitriles
- A61K31/277—Nitriles; Isonitriles having a ring, e.g. verapamil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
- A61K31/36—Compounds containing methylenedioxyphenyl groups, e.g. sesamin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Emergency Medicine (AREA)
- Pain & Pain Management (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Urology & Nephrology (AREA)
- Rheumatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US38130502P | 2002-05-17 | 2002-05-17 | |
| US60/381,305 | 2002-05-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU2004136999A true RU2004136999A (ru) | 2006-06-10 |
Family
ID=29550101
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2004136999/14A RU2004136999A (ru) | 2002-05-17 | 2003-05-15 | Способы лечения болевых расстройств желудочно-кишечной и мочеполовой систем, использующие венлфаксин и его производные |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US20040019101A1 (https=) |
| EP (1) | EP1505960A1 (https=) |
| JP (1) | JP2005530779A (https=) |
| KR (1) | KR20050003464A (https=) |
| CN (1) | CN1652758A (https=) |
| AR (1) | AR040033A1 (https=) |
| AU (1) | AU2003232137A1 (https=) |
| BR (1) | BR0310083A (https=) |
| CA (1) | CA2485736A1 (https=) |
| CR (1) | CR7568A (https=) |
| EC (1) | ECSP045436A (https=) |
| IL (1) | IL165216A0 (https=) |
| MX (1) | MXPA04011329A (https=) |
| NO (1) | NO20044868L (https=) |
| NZ (1) | NZ548950A (https=) |
| RU (1) | RU2004136999A (https=) |
| SG (1) | SG165991A1 (https=) |
| TW (1) | TW200402289A (https=) |
| UA (1) | UA81413C2 (https=) |
| WO (1) | WO2003097029A1 (https=) |
| ZA (1) | ZA200410157B (https=) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7550485B2 (en) * | 2003-10-14 | 2009-06-23 | Wyeth | Substituted N-heterocycle derivatives and methods of their use |
| US7419980B2 (en) * | 2003-10-14 | 2008-09-02 | Wyeth | Fused-aryl and heteroaryl derivatives and methods of their use |
| US7491723B2 (en) * | 2003-10-14 | 2009-02-17 | Wyeth | Alkanol and cycloalkanol-amine derivatives and methods of their use |
| US7531543B2 (en) * | 2003-10-14 | 2009-05-12 | Wyeth | Phenylpiperazine cycloalkanol derivatives and methods of their use |
| US7365076B2 (en) * | 2003-10-14 | 2008-04-29 | Wyeth | Substituted aryl cycloalkanol derivatives and methods of their use |
| US7524846B2 (en) * | 2003-10-14 | 2009-04-28 | Wyeth | Arylalkyl- and cycloalkylalkyl-piperazine derivatives and methods of their use |
| US7402698B2 (en) * | 2003-10-14 | 2008-07-22 | Wyeth | Secondary amino-and cycloamino-cycloalkanol derivatives and methods of their use |
| US20060148781A1 (en) * | 2003-11-10 | 2006-07-06 | Lundeen James E | Method and medicine for treating gastrointestinal disorder in a non-human mammal |
| US20070142367A1 (en) * | 2003-11-10 | 2007-06-21 | Lundeen James E | Method and medicine for treating gastrointestinal disorder including fecal incontinence |
| US20050113365A1 (en) * | 2003-11-10 | 2005-05-26 | Sir Isaac Newton Enterprises Llc | Method and medicine for treating gastrointestinal disorder including irritable bowel syndrome |
| US20060148783A1 (en) * | 2003-11-10 | 2006-07-06 | Lundeen James E | Method and medicine for treating gastrointestinal disorder including fecal incontinence |
| US20060148782A1 (en) * | 2003-11-10 | 2006-07-06 | Lundeen James E | Method and medicine for treating a mammal presenting urinary incontinence, urinary urgency, or both |
| US7820690B2 (en) * | 2004-03-19 | 2010-10-26 | Solvay Pharmaceuticals Gmbh | Method of treating or inhibiting a non-digestive tract derived abdominal disorder associated with pain using a 5-HT, receptor antagonist |
| US7517899B2 (en) * | 2004-03-30 | 2009-04-14 | Wyeth | Phenylaminopropanol derivatives and methods of their use |
| US7414052B2 (en) * | 2004-03-30 | 2008-08-19 | Wyeth | Phenylaminopropanol derivatives and methods of their use |
| US20080081067A1 (en) * | 2006-10-03 | 2008-04-03 | Gupta Manishkumar | Sustained release pharmaceutical compositions of venlafaxine and process for preparation thereof |
| GB201007032D0 (en) * | 2010-04-27 | 2010-06-09 | Dormer Tools Ltd | Twist drill for advanced materials |
| CN102095461B (zh) * | 2011-01-18 | 2012-07-18 | 姚贤卿 | 复合型干度质量流量仪及干度标定测量方法 |
| RU2740750C1 (ru) * | 2020-03-27 | 2021-01-20 | Аллан Герович Бениашвили | Средство для лечения функциональных заболеваний желудочно-кишечного тракта |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4535186A (en) * | 1983-04-19 | 1985-08-13 | American Home Products Corporation | 2-Phenyl-2-(1-hydroxycycloalkyl or 1-hydroxycycloalk-2-enyl)ethylamine derivatives |
| ES2208870T3 (es) * | 1996-02-15 | 2004-06-16 | Janssen Pharmaceutica N.V. | Uso de antagonistas del receptor 5ht4 para resolver los efectos gastrointestinales de los inhibidores de la reabsorcion de serotonina. |
| US6579899B1 (en) * | 1998-07-16 | 2003-06-17 | Massachusetts Institute Of Technology | Composition for treatment of stress |
| EP1133299A1 (en) * | 1998-11-23 | 2001-09-19 | Sepracor Inc. | 2-hydroxymethylolanzapine compositions and methods |
| CA2351718A1 (en) * | 1998-11-23 | 2000-06-02 | Sepracor Inc. | Desmethylolanzapine compositions and methods |
| JP2002530340A (ja) * | 1998-11-23 | 2002-09-17 | セプラコール， インク． | オランザピン−ｎ−オキサイドを含む医薬組成物 |
| US6294192B1 (en) * | 1999-02-26 | 2001-09-25 | Lipocine, Inc. | Triglyceride-free compositions and methods for improved delivery of hydrophobic therapeutic agents |
| GB2355191A (en) * | 1999-10-12 | 2001-04-18 | Laxdale Ltd | Combination formulations for fatigue, head injury and strokes |
| CN1662231A (zh) * | 2002-04-24 | 2005-08-31 | 柏树生物科学公司 | 包括应激相关障碍在内的功能性躯体障碍的预防与治疗 |
| AU2003247515A1 (en) * | 2002-06-10 | 2003-12-22 | Wyeth | Novel formate salt of o-desmethyl-venlafaxine |
-
2003
- 2003-05-14 TW TW092113062A patent/TW200402289A/zh unknown
- 2003-05-15 KR KR10-2004-7018585A patent/KR20050003464A/ko not_active Abandoned
- 2003-05-15 IL IL16521603A patent/IL165216A0/xx unknown
- 2003-05-15 UA UA20041210379A patent/UA81413C2/xx unknown
- 2003-05-15 EP EP03753036A patent/EP1505960A1/en not_active Withdrawn
- 2003-05-15 AU AU2003232137A patent/AU2003232137A1/en not_active Withdrawn
- 2003-05-15 SG SG200607202-9A patent/SG165991A1/en unknown
- 2003-05-15 CN CNA038112612A patent/CN1652758A/zh active Pending
- 2003-05-15 WO PCT/US2003/015230 patent/WO2003097029A1/en not_active Ceased
- 2003-05-15 RU RU2004136999/14A patent/RU2004136999A/ru unknown
- 2003-05-15 MX MXPA04011329A patent/MXPA04011329A/es unknown
- 2003-05-15 JP JP2004505028A patent/JP2005530779A/ja active Pending
- 2003-05-15 US US10/438,572 patent/US20040019101A1/en not_active Abandoned
- 2003-05-15 CA CA002485736A patent/CA2485736A1/en not_active Abandoned
- 2003-05-15 BR BR0310083-9A patent/BR0310083A/pt not_active IP Right Cessation
- 2003-05-15 NZ NZ548950A patent/NZ548950A/en unknown
- 2003-05-16 AR ARP030101715A patent/AR040033A1/es unknown
-
2004
- 2004-11-04 CR CR7568A patent/CR7568A/es not_active Application Discontinuation
- 2004-11-09 NO NO20044868A patent/NO20044868L/no not_active Application Discontinuation
- 2004-11-17 EC EC2004005436A patent/ECSP045436A/es unknown
- 2004-12-15 ZA ZA200410157A patent/ZA200410157B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2005530779A (ja) | 2005-10-13 |
| NO20044868L (no) | 2004-12-08 |
| NZ548950A (en) | 2008-01-31 |
| CN1652758A (zh) | 2005-08-10 |
| IL165216A0 (en) | 2005-12-18 |
| MXPA04011329A (es) | 2005-02-14 |
| AU2003232137A1 (en) | 2003-12-02 |
| CA2485736A1 (en) | 2003-11-27 |
| CR7568A (es) | 2005-02-08 |
| AR040033A1 (es) | 2005-03-09 |
| WO2003097029A1 (en) | 2003-11-27 |
| TW200402289A (en) | 2004-02-16 |
| UA81413C2 (en) | 2008-01-10 |
| KR20050003464A (ko) | 2005-01-10 |
| ECSP045436A (es) | 2005-01-03 |
| EP1505960A1 (en) | 2005-02-16 |
| SG165991A1 (en) | 2010-11-29 |
| BR0310083A (pt) | 2005-02-15 |
| ZA200410157B (en) | 2006-05-31 |
| US20040019101A1 (en) | 2004-01-29 |
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