RU2003130734A - Системы доставки косметически и/или терапевтически активного агента к поверхностям ротовой полости с использованием интегрального носителя - Google Patents

Системы доставки косметически и/или терапевтически активного агента к поверхностям ротовой полости с использованием интегрального носителя Download PDF

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Publication number
RU2003130734A
RU2003130734A RU2003130734/15A RU2003130734A RU2003130734A RU 2003130734 A RU2003130734 A RU 2003130734A RU 2003130734/15 A RU2003130734/15 A RU 2003130734/15A RU 2003130734 A RU2003130734 A RU 2003130734A RU 2003130734 A RU2003130734 A RU 2003130734A
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Russia
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agents
oral cavity
cosmetically
therapeutically active
composition
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RU2003130734/15A
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English (en)
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RU2257888C2 (ru
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Джайант РАДЖАЙАХ (US)
Джайант РАДЖАЙАХ
Лайза Кэтрон ЭРНСТ (US)
Лайза Кэтрон ЭРНСТ
Энн Мари КЕЙС (US)
Энн Мария КЕЙС
Уилль м Майкл ГЛЭНДОРФ (US)
Уилльям Майкл ГЛЭНДОРФ
Тинх Нгуйен ХА (US)
Тинх Нгуйен ХА
Кристофер Роберт МЭЙЕР (US)
Кристофер Роберт МЭЙЕР
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Дзе Проктер Энд Гэмбл Компани (US)
Дзе Проктер Энд Гэмбл Компани
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0208—Tissues; Wipes; Patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
    • A61C19/00—Dental auxiliary appliances
    • A61C19/06—Implements for therapeutic treatment
    • A61C19/063—Medicament applicators for teeth or gums, e.g. treatment with fluorides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/20—Halogens; Compounds thereof
    • A61K8/21—Fluorides; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • A61K8/8105—Compositions of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond; Compositions of derivatives of such polymers
    • A61K8/8111—Homopolymers or copolymers of aliphatic olefines, e.g. polyethylene, polyisobutene; Compositions of derivatives of such polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses

Claims (10)

1. Система доставки для доставки активного агента для ухода за полостью рта к поверхностям полости рта, включающая
a) интегральный носитель и
b) композицию, содержащую полибутен с молекулярной массой от 300 до 3000, предпочтительно от 750 до 1500; и разовую дозу одного или нескольких косметически или терапевтически активных агентов, выбранных из группы, состоящей из средств, препятствующих образованию зубного камня, источников фторид-иона, источников иона двухвалентного олова, отбеливающих средств, противомикробных средств и средств, препятствующих образованию зубного налета, противовоспалительных средств, питательных веществ, антиоксидантов, противовирусных средств, противогрибковых средств, анальгетических средств и анестетиков, антагонистов Н-2, компонентов, отличных от полибутена, которые дают ощущение чистоты зубов, ароматизаторов и средств, придающих нужное ощущение, пигментов и красителей, и их смесей, предпочтительно, косметически или терапевтически активный агент выбирают из группы, состоящей из триклозана, пищевой соды, фторида натрия, нитрата калия, нитрата натрия, нистатина, экстракта семян грейпфрута, фторида олова, тетранатрийпирофосфата, монофторфосфата, Опатинта D&C Красного 27, полифосфатов, пероксида карбамида и хлорида цетилпиридиния; где композиция связана с возможностью высвобождения с интегральным носителем.
2. Система доставки по пункту 1, в которой количество указанной композиции составляет менее чем 0,2 г/см2.
3. Система доставки по любому из предыдущих пунктов, в которой указанный интегральный носитель имеет форму гибкой полоски материала, обладающей достаточной гибкостью для образования изогнутой формы на поверхности полости рта, указанная полоска материала принимает форму поверхности рта без постоянной деформации, когда указанную систему доставки приводят в контакт с этой поверхностью, и где указанная гибкая полоска материала включает первую сторону и вторую сторону, и где указанную композицию наносят на указанную вторую сторону указанной гибкой полоски материала.
4. Система доставки по пункту 3, в которой гибкая полоска материала дополнительно включает множество карманов.
5. Система доставки по пунктам 3 или 4, в которой гибкая полоска материала имеет ширину от 0,5 до 4 см, длину от 2 до 12 см и толщину менее чем 1 мм.
6. Продукт для ухода за полостью рта, включающий
a) упаковку и
b) одну или несколько систем доставки для доставки активного компонента для ухода за полостью рта к поверхностям полости рта, включающих интегральный носитель и композицию, содержащую полибутен с молекулярной массой от 300 до 3000 и один или несколько косметически или терапевтически активных агентов, связанных с возможностью высвобождения с интегральным носителем, размещенных внутри указанной упаковки.
7. Способ, обеспечивающий замедленное высвобождение терапевтически и косметически активных агентов к поверхностям полости рта посредством доставки с помощью интегрального носителя композиции, включающей полибутен с молекулярной массой от 300 до 3000 и один или несколько косметически или терапевтически активных агентов, к указанным поверхностям полости рта.
8. Способ по пункту 7, где косметически или терапевтически активный агент представляет собой отбеливающее средство, предпочтительно пероксид карбамида.
9. Способ ингибирования и профилактики гингивита, кариеса, окрашивания, отложений грибков, бактерий и налета в полости рта посредством доставки с помощью интегрального носителя композиции, включающей полибутен с молекулярной массой от 300 до 3000 и косметически или терапевтически активный агент, к указанным поверхностям полости рта.
10. Способ по любому из пунктов 7 или 9, в котором интегральный носитель представляет собой полоску материала.
RU2003130734/15A 2001-03-19 2002-03-15 Системы доставки косметически и/или терапевтически активного агента к поверхностям ротовой полости с использованием интегрального носителя RU2257888C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US27697701P 2001-03-19 2001-03-19
US60/276,977 2001-03-19

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RU2003130734A true RU2003130734A (ru) 2005-03-10
RU2257888C2 RU2257888C2 (ru) 2005-08-10

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Country Status (16)

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US (2) US6514484B2 (ru)
EP (1) EP1370228B1 (ru)
JP (1) JP3945703B2 (ru)
KR (1) KR100648022B1 (ru)
CN (1) CN1236754C (ru)
AT (1) ATE415135T1 (ru)
AU (1) AU2002247356B2 (ru)
CA (1) CA2441860C (ru)
DE (1) DE60230021D1 (ru)
ES (1) ES2316548T3 (ru)
HK (1) HK1066476A1 (ru)
HU (1) HUP0303525A3 (ru)
MX (1) MXPA03008496A (ru)
PL (1) PL204658B1 (ru)
RU (1) RU2257888C2 (ru)
WO (1) WO2002074275A2 (ru)

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ATE415135T1 (de) 2008-12-15
US6514484B2 (en) 2003-02-04
CA2441860C (en) 2008-11-04
CA2441860A1 (en) 2002-09-26
CN1503658A (zh) 2004-06-09
KR100648022B1 (ko) 2006-11-23
MXPA03008496A (es) 2003-12-08
PL364141A1 (en) 2004-12-13
CN1236754C (zh) 2006-01-18
US20030113276A1 (en) 2003-06-19
US6719995B2 (en) 2004-04-13
WO2002074275A3 (en) 2003-06-05
AU2002247356B2 (en) 2005-05-26
HUP0303525A2 (hu) 2004-03-01
KR20030087647A (ko) 2003-11-14
RU2257888C2 (ru) 2005-08-10
EP1370228A2 (en) 2003-12-17
HK1066476A1 (en) 2005-03-24
US20020176827A1 (en) 2002-11-28
HUP0303525A3 (en) 2006-11-28
WO2002074275A2 (en) 2002-09-26
DE60230021D1 (de) 2009-01-08
EP1370228B1 (en) 2008-11-26
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JP2004535372A (ja) 2004-11-25
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