RS65211B1 - Bispecifična antitela protiv ceacam5 i cd47 - Google Patents
Bispecifična antitela protiv ceacam5 i cd47Info
- Publication number
- RS65211B1 RS65211B1 RS20240190A RSP20240190A RS65211B1 RS 65211 B1 RS65211 B1 RS 65211B1 RS 20240190 A RS20240190 A RS 20240190A RS P20240190 A RSP20240190 A RS P20240190A RS 65211 B1 RS65211 B1 RS 65211B1
- Authority
- RS
- Serbia
- Prior art keywords
- antibodies against
- bispecific antibodies
- against ceacam5
- ceacam5
- bispecific
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3007—Carcino-embryonic Antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/40—Immunoglobulins specific features characterized by post-translational modification
- C07K2317/41—Glycosylation, sialylation, or fucosylation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cell Biology (AREA)
- Oncology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Ultra Sonic Daignosis Equipment (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pens And Brushes (AREA)
- Conversion Of X-Rays Into Visible Images (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP20215766 | 2020-12-18 | ||
US202163135996P | 2021-01-11 | 2021-01-11 | |
EP21834934.8A EP4055055B1 (en) | 2020-12-18 | 2021-12-17 | Bispecific antibodies against ceacam5 and cd47 |
PCT/IB2021/061983 WO2022130348A1 (en) | 2020-12-18 | 2021-12-17 | Bispecific antibodies against ceacam5 and cd47 |
Publications (1)
Publication Number | Publication Date |
---|---|
RS65211B1 true RS65211B1 (sr) | 2024-03-29 |
Family
ID=79164846
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RS20240190A RS65211B1 (sr) | 2020-12-18 | 2021-12-17 | Bispecifična antitela protiv ceacam5 i cd47 |
Country Status (16)
Country | Link |
---|---|
US (2) | US11753481B2 (sr) |
EP (1) | EP4055055B1 (sr) |
JP (1) | JP2024501809A (sr) |
KR (1) | KR20230121772A (sr) |
AU (1) | AU2021400227A1 (sr) |
CA (1) | CA3193210A1 (sr) |
CL (1) | CL2023001797A1 (sr) |
CO (1) | CO2023009100A2 (sr) |
ES (1) | ES2967381T3 (sr) |
HR (1) | HRP20240213T1 (sr) |
IL (1) | IL301701A (sr) |
MX (1) | MX2023007220A (sr) |
PE (1) | PE20231386A1 (sr) |
PL (1) | PL4055055T3 (sr) |
RS (1) | RS65211B1 (sr) |
WO (1) | WO2022130348A1 (sr) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2019234576A1 (en) * | 2018-06-03 | 2019-12-12 | Lamkap Bio Beta Ltd. | Bispecific antibodies against ceacam5 and cd47 |
IL301701A (en) | 2020-12-18 | 2023-05-01 | Lamkap Bio Beta Ag | Bispecific antibodies against CEACAM5 and CD47 |
US20240002544A1 (en) * | 2022-03-07 | 2024-01-04 | Novimmune Sa | Cd28 bispecific antibodies for targeted t cell activation |
WO2023242351A1 (en) | 2022-06-16 | 2023-12-21 | Lamkap Bio Beta Ag | Combination therapy of bispecific antibodies against ceacam5 and cd47 and bispecific antibodies against ceacam5 and cd3 |
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US20040132101A1 (en) | 2002-09-27 | 2004-07-08 | Xencor | Optimized Fc variants and methods for their generation |
IL149820A0 (en) | 2002-05-23 | 2002-11-10 | Curetech Ltd | Humanized immunomodulatory monoclonal antibodies for the treatment of neoplastic disease or immunodeficiency |
US7232888B2 (en) | 2002-07-01 | 2007-06-19 | Massachusetts Institute Of Technology | Antibodies against tumor surface antigens |
AU2003288675B2 (en) | 2002-12-23 | 2010-07-22 | Medimmune Limited | Antibodies against PD-1 and uses therefor |
EP2368578A1 (en) | 2003-01-09 | 2011-09-28 | Macrogenics, Inc. | Identification and engineering of antibodies with variant Fc regions and methods of using same |
WO2005018669A1 (en) | 2003-08-18 | 2005-03-03 | Macrogenics, Inc. | Fcϝriib-specific antibodies and methods of use thereof |
NZ545776A (en) | 2003-08-22 | 2009-05-31 | Biogen Idec Inc | Improved antibodies having altered effector function and methods for making the same |
WO2005063815A2 (en) | 2003-11-12 | 2005-07-14 | Biogen Idec Ma Inc. | Fcϝ receptor-binding polypeptide variants and methods related thereto |
JP2007512846A (ja) | 2003-12-04 | 2007-05-24 | ゼンコー・インコーポレイテッド | 増加した宿主ストリング含有量を有する変異体タンパク質の生成方法およびその組成物 |
WO2005092925A2 (en) | 2004-03-24 | 2005-10-06 | Xencor, Inc. | Immunoglobulin variants outside the fc region |
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AU2005335714B2 (en) | 2004-11-10 | 2012-07-26 | Macrogenics, Inc. | Engineering Fc antibody regions to confer effector function |
WO2006105338A2 (en) | 2005-03-31 | 2006-10-05 | Xencor, Inc. | Fc VARIANTS WITH OPTIMIZED PROPERTIES |
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CA3006529A1 (en) | 2016-01-08 | 2017-07-13 | F. Hoffmann-La Roche Ag | Methods of treating cea-positive cancers using pd-1 axis binding antagonists and anti-cea/anti-cd3 bispecific antibodies |
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WO2018098384A1 (en) | 2016-11-22 | 2018-05-31 | Regents Of The University Of California | Segregation modulation for immunotherapy |
US11518810B2 (en) | 2017-05-08 | 2022-12-06 | Shanghai Jmt-Bio Technology Co., Ltd. | Bispecific recombinant protein and use thereof |
CA3070519A1 (en) | 2017-07-21 | 2019-01-24 | Novimmune Sa | Generating multispecific antibody mixtures and methods of uses thereof |
WO2019234576A1 (en) | 2018-06-03 | 2019-12-12 | Lamkap Bio Beta Ltd. | Bispecific antibodies against ceacam5 and cd47 |
EP3831849A1 (en) | 2019-12-02 | 2021-06-09 | LamKap Bio beta AG | Bispecific antibodies against ceacam5 and cd47 |
IL301701A (en) | 2020-12-18 | 2023-05-01 | Lamkap Bio Beta Ag | Bispecific antibodies against CEACAM5 and CD47 |
-
2021
- 2021-12-17 IL IL301701A patent/IL301701A/en unknown
- 2021-12-17 PL PL21834934.8T patent/PL4055055T3/pl unknown
- 2021-12-17 KR KR1020237021786A patent/KR20230121772A/ko unknown
- 2021-12-17 PE PE2023001907A patent/PE20231386A1/es unknown
- 2021-12-17 RS RS20240190A patent/RS65211B1/sr unknown
- 2021-12-17 AU AU2021400227A patent/AU2021400227A1/en active Pending
- 2021-12-17 JP JP2023537025A patent/JP2024501809A/ja active Pending
- 2021-12-17 WO PCT/IB2021/061983 patent/WO2022130348A1/en active Application Filing
- 2021-12-17 HR HRP20240213TT patent/HRP20240213T1/hr unknown
- 2021-12-17 US US17/554,941 patent/US11753481B2/en active Active
- 2021-12-17 EP EP21834934.8A patent/EP4055055B1/en active Active
- 2021-12-17 MX MX2023007220A patent/MX2023007220A/es unknown
- 2021-12-17 CA CA3193210A patent/CA3193210A1/en active Pending
- 2021-12-17 ES ES21834934T patent/ES2967381T3/es active Active
-
2023
- 2023-06-16 CL CL2023001797A patent/CL2023001797A1/es unknown
- 2023-07-07 CO CONC2023/0009100A patent/CO2023009100A2/es unknown
- 2023-07-31 US US18/362,511 patent/US20240101705A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
EP4055055C0 (en) | 2023-11-22 |
CL2023001797A1 (es) | 2024-02-09 |
PL4055055T3 (pl) | 2024-04-15 |
US20220195067A1 (en) | 2022-06-23 |
JP2024501809A (ja) | 2024-01-16 |
US11753481B2 (en) | 2023-09-12 |
CO2023009100A2 (es) | 2023-08-18 |
EP4055055A1 (en) | 2022-09-14 |
US20240101705A1 (en) | 2024-03-28 |
PE20231386A1 (es) | 2023-09-12 |
AU2021400227A9 (en) | 2024-05-30 |
WO2022130348A1 (en) | 2022-06-23 |
HRP20240213T1 (hr) | 2024-04-26 |
AU2021400227A1 (en) | 2023-04-27 |
MX2023007220A (es) | 2023-08-25 |
CA3193210A1 (en) | 2022-06-23 |
IL301701A (en) | 2023-05-01 |
ES2967381T3 (es) | 2024-04-30 |
KR20230121772A (ko) | 2023-08-21 |
EP4055055B1 (en) | 2023-11-22 |
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