PL4055055T3 - Przeciwciała dwuswoiste przeciwko ceacam5 i cd47 - Google Patents
Przeciwciała dwuswoiste przeciwko ceacam5 i cd47Info
- Publication number
- PL4055055T3 PL4055055T3 PL21834934.8T PL21834934T PL4055055T3 PL 4055055 T3 PL4055055 T3 PL 4055055T3 PL 21834934 T PL21834934 T PL 21834934T PL 4055055 T3 PL4055055 T3 PL 4055055T3
- Authority
- PL
- Poland
- Prior art keywords
- antibodies against
- bispecific antibodies
- against ceacam5
- ceacam5
- bispecific
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3007—Carcino-embryonic Antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/40—Immunoglobulins specific features characterized by post-translational modification
- C07K2317/41—Glycosylation, sialylation, or fucosylation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cell Biology (AREA)
- Oncology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Ultra Sonic Daignosis Equipment (AREA)
- Pens And Brushes (AREA)
- Conversion Of X-Rays Into Visible Images (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP20215766 | 2020-12-18 | ||
| US202163135996P | 2021-01-11 | 2021-01-11 | |
| PCT/IB2021/061983 WO2022130348A1 (en) | 2020-12-18 | 2021-12-17 | Bispecific antibodies against ceacam5 and cd47 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL4055055T3 true PL4055055T3 (pl) | 2024-04-15 |
Family
ID=79164846
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL21834934.8T PL4055055T3 (pl) | 2020-12-18 | 2021-12-17 | Przeciwciała dwuswoiste przeciwko ceacam5 i cd47 |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US11753481B2 (pl) |
| EP (1) | EP4055055B1 (pl) |
| JP (1) | JP2024501809A (pl) |
| KR (1) | KR20230121772A (pl) |
| AU (1) | AU2021400227A1 (pl) |
| CA (1) | CA3193210A1 (pl) |
| CL (1) | CL2023001797A1 (pl) |
| CO (1) | CO2023009100A2 (pl) |
| ES (1) | ES2967381T3 (pl) |
| HR (1) | HRP20240213T1 (pl) |
| HU (1) | HUE065728T2 (pl) |
| IL (1) | IL301701A (pl) |
| MX (1) | MX2023007220A (pl) |
| PE (1) | PE20231386A1 (pl) |
| PL (1) | PL4055055T3 (pl) |
| RS (1) | RS65211B1 (pl) |
| WO (1) | WO2022130348A1 (pl) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7403479B2 (ja) * | 2018-06-03 | 2023-12-22 | ランカプ バイオ ベータ リミテッド | Ceacam5およびcd47に対する二重特異性抗体 |
| RS65211B1 (sr) | 2020-12-18 | 2024-03-29 | Lamkap Bio Beta Ag | Bispecifična antitela protiv ceacam5 i cd47 |
| WO2023170474A1 (en) * | 2022-03-07 | 2023-09-14 | Novimmune Sa | Cd28 bispecific antibodies for targeted t cell activation |
| US12122850B2 (en) * | 2022-03-14 | 2024-10-22 | LamKap Bio gamma AG | Bispecific GPC3xCD28 and GPC3xCD3 antibodies and their combination for targeted killing of GPC3 positive malignant cells |
| KR20250025384A (ko) | 2022-06-16 | 2025-02-21 | 람카프 바이오 베타 엘티디. | Ceacam5 및 cd47에 대한 이중특이적 항체 및 ceacam5 및 cd3에 대한 이중특이적 항체의 조합 요법 |
| WO2025100827A1 (ko) * | 2023-11-09 | 2025-05-15 | 주식회사 다안바이오테라퓨틱스 | 항 ceacam5 항체 및 이의 용도 |
Family Cites Families (75)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6294372B1 (en) | 1997-03-14 | 2001-09-25 | University Of Victoria Innovation & Dev. Corp. | Replication genes and gene products from small cryptic plasmids and methods for constructing controlled-replication plasmid vectors |
| US6946292B2 (en) | 2000-10-06 | 2005-09-20 | Kyowa Hakko Kogyo Co., Ltd. | Cells producing antibody compositions with increased antibody dependent cytotoxic activity |
| US20040132101A1 (en) | 2002-09-27 | 2004-07-08 | Xencor | Optimized Fc variants and methods for their generation |
| IL149820A0 (en) | 2002-05-23 | 2002-11-10 | Curetech Ltd | Humanized immunomodulatory monoclonal antibodies for the treatment of neoplastic disease or immunodeficiency |
| US7232888B2 (en) | 2002-07-01 | 2007-06-19 | Massachusetts Institute Of Technology | Antibodies against tumor surface antigens |
| CN1753912B (zh) | 2002-12-23 | 2011-11-02 | 惠氏公司 | 抗pd-1抗体及其用途 |
| EP2368578A1 (en) | 2003-01-09 | 2011-09-28 | Macrogenics, Inc. | Identification and engineering of antibodies with variant Fc regions and methods of using same |
| AU2003265522A1 (en) | 2003-08-18 | 2005-03-10 | Macrogenics, Inc. | FCGammaRIIB-SPECIFIC ANTIBODIES AND METHODS OF USE THEREOF |
| NZ545776A (en) | 2003-08-22 | 2009-05-31 | Biogen Idec Inc | Improved antibodies having altered effector function and methods for making the same |
| WO2005063815A2 (en) | 2003-11-12 | 2005-07-14 | Biogen Idec Ma Inc. | Fcϝ receptor-binding polypeptide variants and methods related thereto |
| JP2007512846A (ja) | 2003-12-04 | 2007-05-24 | ゼンコー・インコーポレイテッド | 増加した宿主ストリング含有量を有する変異体タンパク質の生成方法およびその組成物 |
| US7276585B2 (en) | 2004-03-24 | 2007-10-02 | Xencor, Inc. | Immunoglobulin variants outside the Fc region |
| MXPA06012601A (es) | 2004-05-10 | 2007-05-10 | Macrogenics Inc | Anticuerpos especificos de fcy riib humanizados y metodos de uso de los mismos. |
| WO2006085967A2 (en) | 2004-07-09 | 2006-08-17 | Xencor, Inc. | OPTIMIZED ANTI-CD20 MONOCONAL ANTIBODIES HAVING Fc VARIANTS |
| CN103172731A (zh) | 2004-07-15 | 2013-06-26 | 赞科股份有限公司 | 优化的Fc变体 |
| WO2006023420A2 (en) | 2004-08-16 | 2006-03-02 | Medimmune, Inc. | Integrin antagonists with enhanced antibody dependent cell-mediated cytotoxicity activity |
| WO2006047350A2 (en) | 2004-10-21 | 2006-05-04 | Xencor, Inc. | IgG IMMUNOGLOBULIN VARIANTS WITH OPTIMIZED EFFECTOR FUNCTION |
| US7632497B2 (en) | 2004-11-10 | 2009-12-15 | Macrogenics, Inc. | Engineering Fc Antibody regions to confer effector function |
| EP1871808A2 (en) | 2005-03-31 | 2008-01-02 | Xencor, Inc. | Fc VARIANTS WITH OPTIMIZED PROPERTIES |
| WO2006116260A2 (en) | 2005-04-26 | 2006-11-02 | Medimmune, Inc. | Modulation of antibody effector function by hinge domain engineering |
| ES2720160T3 (es) | 2005-05-09 | 2019-07-18 | Ono Pharmaceutical Co | Anticuerpos monoclonales humanos contra muerte programada 1(PD-1) y métodos para tratar el cáncer usando anticuerpos dirigidos contra PD-1 solos o junto con otras sustancias inmunoterapéuticas |
| EA019344B1 (ru) | 2005-07-01 | 2014-03-31 | МЕДАРЕКС, Эл.Эл.Си. | Человеческие моноклональные антитела против лиганда-1 запрограммированной гибели клеток (pd-l1) и их применения |
| US7557190B2 (en) | 2005-07-08 | 2009-07-07 | Xencor, Inc. | Optimized proteins that target Ep-CAM |
| CA2618681C (en) | 2005-08-10 | 2015-10-27 | Macrogenics, Inc. | Identification and engineering of antibodies with variant fc regions and methods of using same |
| AU2006299429B2 (en) | 2005-10-03 | 2012-02-23 | Xencor, Inc. | Fc variants with optimized Fc receptor binding properties |
| US7973136B2 (en) | 2005-10-06 | 2011-07-05 | Xencor, Inc. | Optimized anti-CD30 antibodies |
| JP5328019B2 (ja) | 2005-10-21 | 2013-10-30 | レヴォ バイオロジクス インコーポレイテッド | 抗体依存性細胞障害活性を増強させた抗体、その調製法および使用法 |
| WO2007071426A1 (en) | 2005-12-21 | 2007-06-28 | Micromet Ag | Pharmaceutical compositions with resistance to soluble cea |
| JP2009529331A (ja) | 2006-03-10 | 2009-08-20 | マクロジェニクス,インコーポレーテッド | 変異型重鎖を有する抗体の同定および工学的改変ならびにその使用方法 |
| IL177158A0 (en) | 2006-07-30 | 2008-01-20 | Assaf Klar | Method for designing and implementing improved longitudinal flexibility multilayered pipeline |
| JP5825756B2 (ja) | 2006-08-14 | 2015-12-02 | ゼンコー・インコーポレイテッドXencor、 Inc. | Cd19を標的とする最適化抗体 |
| WO2008036688A2 (en) | 2006-09-18 | 2008-03-27 | Xencor, Inc. | Optimized antibodies that target hm1.24 |
| WO2008121160A2 (en) | 2006-11-21 | 2008-10-09 | Xencor, Inc. | Optimized antibodies that target cd5 |
| WO2008140603A2 (en) | 2006-12-08 | 2008-11-20 | Macrogenics, Inc. | METHODS FOR THE TREATMENT OF DISEASE USING IMMUNOGLOBULINS HAVING FC REGIONS WITH ALTERED AFFINITIES FOR FCγR ACTIVATING AND FCγR INHIBITING |
| WO2008091798A2 (en) | 2007-01-22 | 2008-07-31 | Xencor, Inc. | Optimized ca9 antibodies and methods of using the same |
| WO2008091954A2 (en) | 2007-01-23 | 2008-07-31 | Xencor, Inc. | Optimized cd40 antibodies and methods of using the same |
| WO2008092117A2 (en) | 2007-01-25 | 2008-07-31 | Xencor, Inc. | Immunoglobulins with modifications in the fcr binding region |
| WO2008098115A2 (en) | 2007-02-07 | 2008-08-14 | Xencor, Inc. | Optimized igf-1r antibodies and methods of using the same |
| DK2176298T3 (en) | 2007-05-30 | 2018-02-12 | Xencor Inc | Methods and compositions for inhibiting CD32B-expressing cells |
| JP5191537B2 (ja) | 2007-06-18 | 2013-05-08 | エム・エス・ディー・オス・ベー・フェー | ヒトのプログラムされたデスレセプターpd−1に対する抗体 |
| EP2242773B1 (en) | 2008-02-11 | 2017-06-14 | Cure Tech Ltd. | Monoclonal antibodies for tumor treatment |
| EP2262837A4 (en) | 2008-03-12 | 2011-04-06 | Merck Sharp & Dohme | PD-1 BINDING PROTEINS |
| ES2458541T5 (en) | 2008-05-02 | 2025-08-04 | Seagen Inc | Methods and compositions for making antibodies and antibody derivatives with reduced core fucosylation |
| RS54233B1 (sr) | 2008-08-25 | 2015-12-31 | Amplimmune Inc. | Kompozicije pd-1 antagonista i postupci za njihovu primenu |
| EP2328920A2 (en) | 2008-08-25 | 2011-06-08 | Amplimmune, Inc. | Targeted costimulatory polypeptides and methods of use to treat cancer |
| WO2010033736A1 (en) | 2008-09-17 | 2010-03-25 | Xencor, Inc. | Novel compositons and methods for treating ige-mediated disorders |
| HUE065752T2 (hu) | 2008-12-09 | 2024-06-28 | Hoffmann La Roche | Anti-PD-L1 antitestek és felhasználásuk T-sejt funkció elõsegítésére |
| EP2478110B1 (en) | 2009-09-16 | 2016-01-06 | Immunomedics, Inc. | Class i anti-cea antibodies and uses thereof |
| US8642292B2 (en) | 2009-09-22 | 2014-02-04 | Probiogen Ag | Process for producing molecules containing specialized glycan structures |
| RU2608640C2 (ru) | 2010-08-16 | 2017-01-23 | Новиммун С.А. | Способы получения мультиспецифичных и мультивалентных антител |
| BR112013021460B1 (pt) | 2011-03-02 | 2022-12-20 | Roche Glycart Ag | Anticorpos, composição e uso do anticorpo |
| WO2013012414A1 (en) | 2011-07-18 | 2013-01-24 | Medimmune, Llc | Dosing regimens for treatment of cea-expressing cancers |
| EA026924B1 (ru) | 2011-08-01 | 2017-05-31 | Дженентек, Инк. | Способы лечения рака с использованием антагонистов, связывающихся с осью pd-1, и ингибиторов mek |
| WO2013088259A2 (en) | 2011-10-19 | 2013-06-20 | Novimmune S.A. | Methods of purifying antibodies |
| US20140140989A1 (en) | 2012-02-06 | 2014-05-22 | Inhibrx Llc | Non-Platelet Depleting and Non-Red Blood Cell Depleting CD47 Antibodies and Methods of Use Thereof |
| US9212224B2 (en) | 2012-05-15 | 2015-12-15 | Bristol-Myers Squibb Company | Antibodies that bind PD-L1 and uses thereof |
| JP6392770B2 (ja) | 2012-12-03 | 2018-09-19 | ノビミューン エスアー | 抗cd47抗体およびその使用方法 |
| US9738722B2 (en) | 2013-01-15 | 2017-08-22 | Xencor, Inc. | Rapid clearance of antigen complexes using novel antibodies |
| WO2014131711A1 (en) | 2013-02-26 | 2014-09-04 | Roche Glycart Ag | Bispecific t cell activating antigen binding molecules |
| UA119320C2 (uk) | 2013-02-26 | 2019-06-10 | Рош Глікарт Аг | Активуюча т-клітини біспецифічна антигензв'язувальна молекула |
| JP6586087B2 (ja) | 2013-08-20 | 2019-10-02 | メルク・シャープ・アンド・ドーム・コーポレーションMerck Sharp & Dohme Corp. | Pd−1アンタゴニストとジナシクリブとの組合せでの癌治療 |
| EP3096782A4 (en) | 2014-01-21 | 2017-07-26 | Medlmmune, LLC | Compositions and methods for modulating and redirecting immune responses |
| BR112017000497B1 (pt) | 2014-07-11 | 2023-12-26 | Ventana Medical Systems, Inc | Anticorpo isolado, célula hospedeira procariótica, imunoconjugado e método de detecção da presença ou do nível de expressão de pd-l1 |
| PT3277821T (pt) | 2015-03-31 | 2019-10-31 | Novimmune Sa | Método para otimizar a montagem e produção de complexos proteicos hetero-multiméricos |
| KR20180073561A (ko) | 2015-10-02 | 2018-07-02 | 에프. 호프만-라 로슈 아게 | 이중특이적 항-ceaxcd3 t 세포 활성화 항원 결합 분자 |
| GB2546072B (en) | 2016-01-05 | 2019-07-10 | Bja Trading Ltd | Attachment assembly and method of using same |
| AR107303A1 (es) | 2016-01-08 | 2018-04-18 | Hoffmann La Roche | Métodos de tratamiento de cánceres positivos para ace utilizando antagonistas de unión a eje pd-1 y anticuerpos biespecíficos anti-ace / anti-cd3, uso, composición, kit |
| AR112048A1 (es) | 2016-05-09 | 2019-09-18 | Celgene Corp | Anticuerpos cd47 y métodos de uso de los mismos |
| US11673971B2 (en) | 2016-09-23 | 2023-06-13 | Marengo Therapeutics, Inc. | Multispecific antibody molecules comprising lambda and kappa light chains |
| WO2018098384A1 (en) | 2016-11-22 | 2018-05-31 | Regents Of The University Of California | Segregation modulation for immunotherapy |
| AU2018264321B2 (en) | 2017-05-08 | 2025-03-06 | Shanghai Jmt-Bio Technology Co., Ltd. | Bispecific recombinant protein and use thereof |
| WO2019016411A1 (en) | 2017-07-21 | 2019-01-24 | Novimmune Sa | GENERATION OF MULTISPECIFIC ANTIBODY MIXTURES AND METHODS OF USE |
| JP7403479B2 (ja) * | 2018-06-03 | 2023-12-22 | ランカプ バイオ ベータ リミテッド | Ceacam5およびcd47に対する二重特異性抗体 |
| EP3831849A1 (en) | 2019-12-02 | 2021-06-09 | LamKap Bio beta AG | Bispecific antibodies against ceacam5 and cd47 |
| RS65211B1 (sr) | 2020-12-18 | 2024-03-29 | Lamkap Bio Beta Ag | Bispecifična antitela protiv ceacam5 i cd47 |
-
2021
- 2021-12-17 RS RS20240190A patent/RS65211B1/sr unknown
- 2021-12-17 AU AU2021400227A patent/AU2021400227A1/en active Pending
- 2021-12-17 HR HRP20240213TT patent/HRP20240213T1/hr unknown
- 2021-12-17 MX MX2023007220A patent/MX2023007220A/es unknown
- 2021-12-17 ES ES21834934T patent/ES2967381T3/es active Active
- 2021-12-17 JP JP2023537025A patent/JP2024501809A/ja active Pending
- 2021-12-17 KR KR1020237021786A patent/KR20230121772A/ko active Pending
- 2021-12-17 IL IL301701A patent/IL301701A/en unknown
- 2021-12-17 EP EP21834934.8A patent/EP4055055B1/en active Active
- 2021-12-17 PL PL21834934.8T patent/PL4055055T3/pl unknown
- 2021-12-17 HU HUE21834934A patent/HUE065728T2/hu unknown
- 2021-12-17 PE PE2023001907A patent/PE20231386A1/es unknown
- 2021-12-17 WO PCT/IB2021/061983 patent/WO2022130348A1/en not_active Ceased
- 2021-12-17 CA CA3193210A patent/CA3193210A1/en active Pending
- 2021-12-17 US US17/554,941 patent/US11753481B2/en active Active
-
2023
- 2023-06-16 CL CL2023001797A patent/CL2023001797A1/es unknown
- 2023-07-07 CO CONC2023/0009100A patent/CO2023009100A2/es unknown
- 2023-07-31 US US18/362,511 patent/US20240101705A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AU2021400227A1 (en) | 2023-04-27 |
| HUE065728T2 (hu) | 2024-06-28 |
| WO2022130348A1 (en) | 2022-06-23 |
| CA3193210A1 (en) | 2022-06-23 |
| EP4055055A1 (en) | 2022-09-14 |
| US20240101705A1 (en) | 2024-03-28 |
| KR20230121772A (ko) | 2023-08-21 |
| AU2021400227A9 (en) | 2024-05-30 |
| CL2023001797A1 (es) | 2024-02-09 |
| IL301701A (en) | 2023-05-01 |
| JP2024501809A (ja) | 2024-01-16 |
| CO2023009100A2 (es) | 2023-08-18 |
| HRP20240213T1 (hr) | 2024-04-26 |
| EP4055055B1 (en) | 2023-11-22 |
| PE20231386A1 (es) | 2023-09-12 |
| MX2023007220A (es) | 2023-08-25 |
| ES2967381T3 (es) | 2024-04-30 |
| US11753481B2 (en) | 2023-09-12 |
| EP4055055C0 (en) | 2023-11-22 |
| RS65211B1 (sr) | 2024-03-29 |
| US20220195067A1 (en) | 2022-06-23 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HUE065728T2 (hu) | CEACAM5 és CD47 elleni bispecifikus antitestek | |
| IL291482A (en) | Bispecific antibodies against ceacam5 and cd3 | |
| EP3802599C0 (en) | BISPECIFIC ANTIBODIES AGAINST CEACAM5 AND CD47 | |
| EP4010378A4 (en) | ANTICCR8 MONOCLONAL ANTIBODIES AND USES THEREOF | |
| SI3872091T1 (sl) | Protitelesa proti SARS-COV-2 | |
| ZA202208807B (en) | Anti-tigit antibodies and usage method | |
| DK3823664T3 (da) | Bispecifikke anti BCMA-X-anti CD3-antistoffer og anvendelser deraf | |
| ZA202105150B (en) | Conjugate comprising ligand and ceacam5 antibody fab fragment | |
| SG11202012137UA (en) | Methods for treating cancer with bispecific anti-cd3xmuc16 antibodies and anti-pd-1 antibodies | |
| LT4274851T (lt) | Anti-gprc5d monokloniniai antikūnai ir jų panaudojimas | |
| IL307519A (en) | Antibodies against ILT4, anti-ILT4\PD-L1 bispecific antibody and their uses | |
| IL310662A (en) | Anti-CD161 antibodies and their uses | |
| EP3988574A4 (en) | AGAINST HER2 BI-SPECIFIC ANTIBODIES AND THEIR USE | |
| IL307940A (en) | Anti-ADGRE2 antibodies and their uses | |
| IL291082A (en) | Anti-vsig4 antibody or antigen-binding fragment and uses thereof | |
| EP4382541A4 (en) | BISPECIFIC ANTIBODY AND USE THEREOF | |
| IL291049A (en) | Anti-cd47 monoclonal antibody and use thereof | |
| EP4004054A4 (en) | ANTI-HER2/ANTI-4-1BB BISPECIFIC ANTIBODIES AND ITS APPLICATION | |
| IL315888A (en) | Transgenic CD200R antibodies and their uses | |
| TWI799855B (zh) | 抗新型冠狀病毒(SARS-CoV-2)之新穎單株抗體及其應用 | |
| IL314678A (en) | Bispecific antibodies against cd277 and a tumor-antigen | |
| IL285569A (en) | Anti-pd-l1 antibody and use thereof | |
| EP4303231A4 (en) | BISPECIFIC ANTIBODY | |
| IL272733A (en) | Monoclonal antibodies against pathological alpha-synuclein, and methods using same | |
| IL307939A (en) | Anti-CLEC12A antibodies and uses thereof |