RS52731B - Farmaceutska kompozicija za upotrebu u lečenju ateroskleroze, dislipidemija i sa njima povezanih stanja - Google Patents

Farmaceutska kompozicija za upotrebu u lečenju ateroskleroze, dislipidemija i sa njima povezanih stanja

Info

Publication number
RS52731B
RS52731B YU20050777A YUP77705A RS52731B RS 52731 B RS52731 B RS 52731B YU 20050777 A YU20050777 A YU 20050777A YU P77705 A YUP77705 A YU P77705A RS 52731 B RS52731 B RS 52731B
Authority
RS
Serbia
Prior art keywords
pharmaceutical composition
dyslipidemias
related conditions
treating atherosclerosis
pharmaceutically acceptable
Prior art date
Application number
YU20050777A
Other languages
English (en)
Inventor
Kang Cheng
M. Gerard Waters
Kathleen M. Metters
Gary O'neill
Original Assignee
Merck Sharp & Dohme Corp.
Merck Canada Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=33476734&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=RS52731(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Merck Sharp & Dohme Corp., Merck Canada Inc. filed Critical Merck Sharp & Dohme Corp.
Publication of RS20050777A publication Critical patent/RS20050777A/sr
Publication of RS52731B publication Critical patent/RS52731B/sr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/538—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with carbocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/69—Boron compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)

Abstract

Farmaceutska kompozicija koja sadrži jedinjenje E, ili njegovu farmaceutski prihvatljivu so ili solvat:nikotinsku kiselinu ili njenu farmaceutski prihvatljivu so ili solvat i inhibitor HMG Co-A reduktaze u kombinaciji sa farmaceutski prihvatljivim nosačem.Prijava sadrži još 5 patentnih zahteva.
YU20050777A 2003-05-15 2004-05-13 Farmaceutska kompozicija za upotrebu u lečenju ateroskleroze, dislipidemija i sa njima povezanih stanja RS52731B (sr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US47066503P 2003-05-15 2003-05-15
PCT/US2004/014980 WO2004103370A1 (en) 2003-05-15 2004-05-13 Method of treating atherosclerosis, dyslipidemias and related conditions and pharmaceutical compositions

Publications (2)

Publication Number Publication Date
RS20050777A RS20050777A (sr) 2008-04-04
RS52731B true RS52731B (sr) 2013-08-30

Family

ID=33476734

Family Applications (3)

Application Number Title Priority Date Filing Date
RS20120498A RS20120498A1 (sr) 2003-05-15 2004-05-13 Postupak za lečenje ateroskleroze, dislipidemija i sa njima povezanih stanja i farmaceutske kompozicije
RS20120499A RS20120499A1 (sr) 2003-05-15 2004-05-13 Postupak za lečenje ateroskleroze, dislipidemija i sa njima povezanih stanja i farmaceutske kompozicije
YU20050777A RS52731B (sr) 2003-05-15 2004-05-13 Farmaceutska kompozicija za upotrebu u lečenju ateroskleroze, dislipidemija i sa njima povezanih stanja

Family Applications Before (2)

Application Number Title Priority Date Filing Date
RS20120498A RS20120498A1 (sr) 2003-05-15 2004-05-13 Postupak za lečenje ateroskleroze, dislipidemija i sa njima povezanih stanja i farmaceutske kompozicije
RS20120499A RS20120499A1 (sr) 2003-05-15 2004-05-13 Postupak za lečenje ateroskleroze, dislipidemija i sa njima povezanih stanja i farmaceutske kompozicije

Country Status (45)

Country Link
US (4) US20040229844A1 (sr)
EP (3) EP2286816A1 (sr)
JP (2) JP4637833B2 (sr)
KR (2) KR100806008B1 (sr)
CN (3) CN101559227B (sr)
AR (1) AR041089A1 (sr)
AU (2) AU2004240597B2 (sr)
BR (1) BRPI0410273A (sr)
CA (1) CA2525772C (sr)
CL (1) CL2004001056A1 (sr)
CO (1) CO5630034A2 (sr)
CR (2) CR8047A (sr)
CY (2) CY1109476T1 (sr)
DE (1) DE602004022036D1 (sr)
DK (2) DK2116244T3 (sr)
DO (1) DOP2004000907A (sr)
EA (2) EA009744B1 (sr)
EC (1) ECSP056156A (sr)
ES (2) ES2392743T3 (sr)
GE (2) GEP20084569B (sr)
GT (1) GT200400098A (sr)
HK (1) HK1092722A1 (sr)
HN (1) HN2004000171A (sr)
HR (2) HRP20090424T1 (sr)
IL (1) IL171962A (sr)
IS (1) IS2708B (sr)
JO (1) JO2564B1 (sr)
MA (1) MA27835A1 (sr)
ME (1) MEP60108A (sr)
MX (1) MXPA05012272A (sr)
MY (1) MY140639A (sr)
NO (1) NO20055957L (sr)
NZ (2) NZ572515A (sr)
PA (1) PA8603201A1 (sr)
PE (1) PE20050552A1 (sr)
PL (2) PL1624871T3 (sr)
PT (2) PT2116244E (sr)
RS (3) RS20120498A1 (sr)
SG (1) SG153667A1 (sr)
SI (2) SI2116244T1 (sr)
TN (1) TNSN05290A1 (sr)
TW (2) TWI334354B (sr)
UA (1) UA89615C2 (sr)
WO (1) WO2004103370A1 (sr)
ZA (1) ZA200508288B (sr)

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