RS40804A - Process for reacting alkaloids and use of the reaction products in the preparation of medicaments - Google Patents
Process for reacting alkaloids and use of the reaction products in the preparation of medicamentsInfo
- Publication number
- RS40804A RS40804A YU40804A YUP40804A RS40804A RS 40804 A RS40804 A RS 40804A YU 40804 A YU40804 A YU 40804A YU P40804 A YUP40804 A YU P40804A RS 40804 A RS40804 A RS 40804A
- Authority
- RS
- Serbia
- Prior art keywords
- reaction products
- alkaloids
- medicaments
- preparation
- reacting
- Prior art date
Links
- 229930013930 alkaloid Natural products 0.000 title abstract 4
- 239000007795 chemical reaction product Substances 0.000 title abstract 3
- 239000003814 drug Substances 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 150000003017 phosphorus Chemical class 0.000 abstract 2
- 229940079593 drug Drugs 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07G—COMPOUNDS OF UNKNOWN CONSTITUTION
- C07G5/00—Alkaloids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/564—Three-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/576—Six-membered rings
- C07F9/59—Hydrogenated pyridine rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
- C07F9/6509—Six-membered rings
- C07F9/650952—Six-membered rings having the nitrogen atoms in the positions 1 and 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6527—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having nitrogen and oxygen atoms as the only ring hetero atoms
- C07F9/6533—Six-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6536—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having nitrogen and sulfur atoms with or without oxygen atoms, as the only ring hetero atoms
- C07F9/6539—Five-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
- C07F9/6581—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms
- C07F9/6584—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms having one phosphorus atom as ring hetero atom
- C07F9/65842—Cyclic amide derivatives of acids of phosphorus, in which one nitrogen atom belongs to the ring
- C07F9/65846—Cyclic amide derivatives of acids of phosphorus, in which one nitrogen atom belongs to the ring the phosphorus atom being part of a six-membered ring which may be condensed with another ring system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Biomedical Technology (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Hematology (AREA)
- Pain & Pain Management (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Obesity (AREA)
- Dermatology (AREA)
- Psychiatry (AREA)
- Oncology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Pulmonology (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Ovaj pronalazak se odnosi na postupak za reagovanje alkaloida dodavanjem derivata fosfora u organski rastvor alkaloida, a organski rastvor koji sadrži proizvode reakcije alkaloida i neizreagovali ostatak derivata fosfora se zatim pere vodom. Dobijeni proizvodi reakcije su pogodni kao lekovi.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH02094/01A CH695417A5 (de) | 2001-11-15 | 2001-11-15 | Verfahren zur Umsetzung von Alkaloiden. |
PCT/EP2002/012003 WO2003041721A1 (en) | 2001-11-15 | 2002-10-28 | Process for reacting alkaloids and use of the reaction products in the preparation of medicaments |
Publications (2)
Publication Number | Publication Date |
---|---|
RS40804A true RS40804A (en) | 2006-12-15 |
RS51219B RS51219B (sr) | 2010-12-31 |
Family
ID=4567486
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
YUP-408/04A RS51219B (sr) | 2001-11-15 | 2002-10-28 | Postupak za reagovanje alkaloida i upotreba proizvoda reakcije za dobijanje medikamenata |
Country Status (39)
Country | Link |
---|---|
US (1) | US20050043340A1 (sr) |
EP (1) | EP1443943B1 (sr) |
JP (1) | JP2005509006A (sr) |
KR (1) | KR100849488B1 (sr) |
CN (1) | CN100436462C (sr) |
AR (1) | AR037527A1 (sr) |
AT (1) | ATE485826T1 (sr) |
AU (1) | AU2002346888B2 (sr) |
BR (1) | BR0214173A (sr) |
CA (1) | CA2465723C (sr) |
CH (1) | CH695417A5 (sr) |
CO (1) | CO5580784A2 (sr) |
CR (1) | CR7340A (sr) |
CU (1) | CU23451B7 (sr) |
CY (1) | CY1111139T1 (sr) |
DE (1) | DE60238134D1 (sr) |
DK (1) | DK1443943T3 (sr) |
EA (1) | EA007097B1 (sr) |
EC (1) | ECSP045107A (sr) |
ES (1) | ES2353207T3 (sr) |
GE (1) | GEP20053701B (sr) |
HK (1) | HK1054041A1 (sr) |
HR (1) | HRP20040430A2 (sr) |
HU (1) | HU229688B1 (sr) |
IL (2) | IL161766A0 (sr) |
IS (1) | IS2812B (sr) |
MA (1) | MA26232A1 (sr) |
MX (1) | MXPA04004643A (sr) |
NO (1) | NO334701B1 (sr) |
NZ (1) | NZ532941A (sr) |
PL (1) | PL212111B1 (sr) |
PT (1) | PT1443943E (sr) |
RS (1) | RS51219B (sr) |
SA (1) | SA02230496B1 (sr) |
TN (1) | TNSN04084A1 (sr) |
TW (1) | TWI262080B (sr) |
UA (1) | UA76535C2 (sr) |
WO (1) | WO2003041721A1 (sr) |
ZA (1) | ZA200403371B (sr) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1459753A1 (en) | 2003-03-18 | 2004-09-22 | Nowicky, Wassyl, Dipl.-Ing. DDr. | Quaternary chelidonine and alkaloid derivatives, process for their preparation and their use in the manufacture of medicaments |
WO2006053649A1 (en) * | 2004-11-19 | 2006-05-26 | Nowicky Wassili | Method for the detection of cancer |
WO2006053680A1 (en) * | 2004-11-19 | 2006-05-26 | Nowicky Wassili | Ex vivo cancer diagnostic method |
WO2007073919A2 (en) | 2005-12-28 | 2007-07-05 | Nowicky Wassili | Method and kit for the detection of cancer |
ITMI20080284A1 (it) * | 2008-02-22 | 2009-08-23 | Indena Spa | Agenti antitumorali a struttura benzofenantridinica e formulazioni che li contengono |
CA2941315C (en) * | 2016-08-12 | 2018-03-06 | Api Labs Inc. | High thebaine poppy and methods of producing the same |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3865830A (en) * | 1969-06-16 | 1975-02-11 | Nikolai Mikhailovich Turkevich | Thiophosphamide derivatives of isoquinoline alkaloids, method of producing and application thereof |
SU368254A1 (ru) * | 1969-06-16 | 1973-01-26 | А. И. Потопальский , В. М. Новицкий Львовский государственный медицинский институт | Способ получения соединений тиофосфамида с алкалоидами чистотела большого |
AT354644B (de) * | 1975-12-19 | 1980-01-25 | Nowicky Wassili | Verfahren zur herstellung von neuen salzen von alkaloidderivaten von thiophosphorsaeure |
AT377988B (de) * | 1976-06-28 | 1985-05-28 | Nowicky Wassili | Verfahren zur herstellung von neuen phosphorderivaten von alkaloiden |
DE3128018A1 (de) * | 1981-07-13 | 1983-04-07 | Wassyl 1060 Wien Nowicky | "verfahren zum diagnostizieren und fuer die therapeutische behandlung von tumoren und/oder infektioesen krankheiten verschiedenster art unter praeparativem einsatz von alkaloid-verbindungen bzw. deren salze" |
US4970212A (en) * | 1982-05-18 | 1990-11-13 | Nowicky Wassili | Method of treating human illnesses which compromise the ability to mount an effective immunological response |
AT407608B (de) * | 1994-03-18 | 2001-05-25 | Nowicky Wassili | Mittel zur behandlung von osteoporose |
AT407833B (de) * | 1995-06-01 | 2001-06-25 | Nowicky Wassyl Dr | Mittel zur behandlung von strahlenschäden |
AT408719B (de) * | 2000-03-22 | 2002-02-25 | Nowicky Wassili | Mittel zur behandlung von hepatitis c |
-
2001
- 2001-11-15 CH CH02094/01A patent/CH695417A5/de not_active IP Right Cessation
-
2002
- 2002-10-25 TW TW091125317A patent/TWI262080B/zh not_active IP Right Cessation
- 2002-10-28 BR BR0214173-6A patent/BR0214173A/pt not_active IP Right Cessation
- 2002-10-28 EP EP02783017A patent/EP1443943B1/en not_active Expired - Lifetime
- 2002-10-28 DE DE60238134T patent/DE60238134D1/de not_active Expired - Lifetime
- 2002-10-28 ES ES02783017T patent/ES2353207T3/es not_active Expired - Lifetime
- 2002-10-28 PL PL368879A patent/PL212111B1/pl unknown
- 2002-10-28 MX MXPA04004643A patent/MXPA04004643A/es active IP Right Grant
- 2002-10-28 IL IL16176602A patent/IL161766A0/xx unknown
- 2002-10-28 DK DK02783017.3T patent/DK1443943T3/da active
- 2002-10-28 AT AT02783017T patent/ATE485826T1/de active
- 2002-10-28 AU AU2002346888A patent/AU2002346888B2/en not_active Ceased
- 2002-10-28 NZ NZ532941A patent/NZ532941A/en not_active IP Right Cessation
- 2002-10-28 PT PT02783017T patent/PT1443943E/pt unknown
- 2002-10-28 EA EA200400679A patent/EA007097B1/ru not_active IP Right Cessation
- 2002-10-28 WO PCT/EP2002/012003 patent/WO2003041721A1/en active IP Right Grant
- 2002-10-28 KR KR1020047007480A patent/KR100849488B1/ko not_active IP Right Cessation
- 2002-10-28 US US10/495,729 patent/US20050043340A1/en not_active Abandoned
- 2002-10-28 RS YUP-408/04A patent/RS51219B/sr unknown
- 2002-10-28 HU HU0402365A patent/HU229688B1/hu unknown
- 2002-10-28 GE GE8206A patent/GEP20053701B/en unknown
- 2002-10-28 UA UA20040604558A patent/UA76535C2/uk unknown
- 2002-10-28 CA CA002465723A patent/CA2465723C/en not_active Expired - Fee Related
- 2002-10-28 JP JP2003543608A patent/JP2005509006A/ja active Pending
- 2002-11-15 AR ARP020104397A patent/AR037527A1/es unknown
- 2002-11-15 CN CNB021513384A patent/CN100436462C/zh not_active Expired - Fee Related
- 2002-12-30 SA SA02230496A patent/SA02230496B1/ar unknown
-
2003
- 2003-08-29 HK HK03106188.6A patent/HK1054041A1/xx not_active IP Right Cessation
-
2004
- 2004-04-30 IS IS7245A patent/IS2812B/is unknown
- 2004-05-04 ZA ZA200403371A patent/ZA200403371B/en unknown
- 2004-05-04 IL IL161766A patent/IL161766A/en not_active IP Right Cessation
- 2004-05-05 NO NO20041845A patent/NO334701B1/no not_active IP Right Cessation
- 2004-05-11 CR CR7340A patent/CR7340A/es unknown
- 2004-05-13 TN TNP2004000084A patent/TNSN04084A1/en unknown
- 2004-05-14 MA MA27679A patent/MA26232A1/fr unknown
- 2004-05-14 HR HR20040430A patent/HRP20040430A2/hr not_active IP Right Cessation
- 2004-05-14 EC EC2004005107A patent/ECSP045107A/es unknown
- 2004-05-17 CU CU20040105A patent/CU23451B7/es not_active IP Right Cessation
- 2004-06-01 CO CO04051024A patent/CO5580784A2/es not_active Application Discontinuation
-
2011
- 2011-01-24 CY CY20111100077T patent/CY1111139T1/el unknown
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