WO2004089965A3 - Topiramate and processes for the preparation thereof - Google Patents

Topiramate and processes for the preparation thereof Download PDF

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Publication number
WO2004089965A3
WO2004089965A3 PCT/GB2004/001568 GB2004001568W WO2004089965A3 WO 2004089965 A3 WO2004089965 A3 WO 2004089965A3 GB 2004001568 W GB2004001568 W GB 2004001568W WO 2004089965 A3 WO2004089965 A3 WO 2004089965A3
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WO
WIPO (PCT)
Prior art keywords
topiramate
processes
preparation
same
formula
Prior art date
Application number
PCT/GB2004/001568
Other languages
French (fr)
Other versions
WO2004089965A2 (en
Inventor
Rajendra Narayanrao Kankan
Dharmaraj Ramachandra Rao
Pathi L Srinivas
Original Assignee
Cipla Ltd
Rajendra Narayanrao Kankan
Dharmaraj Ramachandra Rao
Pathi L Srinivas
Wain Christopher Paul
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cipla Ltd, Rajendra Narayanrao Kankan, Dharmaraj Ramachandra Rao, Pathi L Srinivas, Wain Christopher Paul filed Critical Cipla Ltd
Publication of WO2004089965A2 publication Critical patent/WO2004089965A2/en
Publication of WO2004089965A3 publication Critical patent/WO2004089965A3/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7024—Esters of saccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H9/00—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

A process of preparing topiramate of the Formula (I) which comprises the following reaction steps and topiramate prepared thereby, compositions containing the same, therapeutic uses thereof and methods of treatment employing the same.
PCT/GB2004/001568 2003-04-07 2004-04-07 Topiramate and processes for the preparation thereof WO2004089965A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN343/MUM/2003 2003-04-07
IN343MU2003 2003-04-07

Publications (2)

Publication Number Publication Date
WO2004089965A2 WO2004089965A2 (en) 2004-10-21
WO2004089965A3 true WO2004089965A3 (en) 2005-01-20

Family

ID=33156204

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2004/001568 WO2004089965A2 (en) 2003-04-07 2004-04-07 Topiramate and processes for the preparation thereof

Country Status (1)

Country Link
WO (1) WO2004089965A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5643844B2 (en) * 2010-02-05 2014-12-17 サイノファーム タイワン リミテッド Topiramate manufacturing method
US8652527B1 (en) 2013-03-13 2014-02-18 Upsher-Smith Laboratories, Inc Extended-release topiramate capsules
US9101545B2 (en) 2013-03-15 2015-08-11 Upsher-Smith Laboratories, Inc. Extended-release topiramate capsules
CN110655542A (en) * 2018-06-29 2020-01-07 鲁南制药集团股份有限公司 Crystal form of 2,3:4, 5-bis-O- (1-methylethylidene) -beta-D-fructopyranose chlorosulfonate
CN113999228B (en) * 2021-11-08 2022-11-04 南京卓康医药科技有限公司 Synthesis method of tadalafil

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4513006A (en) * 1983-09-26 1985-04-23 Mcneil Lab., Inc. Anticonvulsant sulfamate derivatives

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4513006A (en) * 1983-09-26 1985-04-23 Mcneil Lab., Inc. Anticonvulsant sulfamate derivatives

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
MARYANOFF B E ET AL: "ANTICONVULSANT O-ALKYL SULFAMATES. 2,3:4,5-BIS-O- (1-METHYLETHYLIDENE)-BETA-D-FRUCTOPYRANOSE SULFAMATE AND RELATED COMPOUNDS", JOURNAL OF MEDICINAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY. WASHINGTON, US, vol. 30, no. 5, 1 May 1987 (1987-05-01), pages 880 - 887, XP000647869, ISSN: 0022-2623 *

Also Published As

Publication number Publication date
WO2004089965A2 (en) 2004-10-21

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