RO82359B - Procedeu pentru prepararea unor 4-tiazolidinone - Google Patents
Procedeu pentru prepararea unor 4-tiazolidinoneInfo
- Publication number
- RO82359B RO82359B RO105701A RO10570179A RO82359B RO 82359 B RO82359 B RO 82359B RO 105701 A RO105701 A RO 105701A RO 10570179 A RO10570179 A RO 10570179A RO 82359 B RO82359 B RO 82359B
- Authority
- RO
- Romania
- Prior art keywords
- methyl
- thiazolidinones
- thiomethyl
- group
- preparing
- Prior art date
Links
- NOLHRFLIXVQPSZ-UHFFFAOYSA-N 1,3-thiazolidin-4-one Chemical class O=C1CSCN1 NOLHRFLIXVQPSZ-UHFFFAOYSA-N 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- VLKZOEOYAKHREP-UHFFFAOYSA-N n-Hexane Chemical compound CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 abstract 3
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 2
- MZRVEZGGRBJDDB-UHFFFAOYSA-N N-Butyllithium Chemical compound [Li]CCCC MZRVEZGGRBJDDB-UHFFFAOYSA-N 0.000 abstract 2
- 125000000066 S-methyl group Chemical group [H]C([H])([H])S* 0.000 abstract 2
- WYURNTSHIVDZCO-UHFFFAOYSA-N Tetrahydrofuran Chemical compound C1CCOC1 WYURNTSHIVDZCO-UHFFFAOYSA-N 0.000 abstract 2
- WQOXQRCZOLPYPM-UHFFFAOYSA-N dimethyl disulfide Chemical compound CSSC WQOXQRCZOLPYPM-UHFFFAOYSA-N 0.000 abstract 2
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 125000005059 halophenyl group Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- YLQBMQCUIZJEEH-UHFFFAOYSA-N tetrahydrofuran Natural products C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/02—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having no bond to a nitrogen atom
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/72—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
- A01N43/74—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,3
- A01N43/78—1,3-Thiazoles; Hydrogenated 1,3-thiazoles
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/72—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
- A01N43/86—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms six-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,3
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
Inventia se refera la un procedeu pentru prepararea unor 4-tiazolidinone cu formula din pag.1 a descrierii, în care R este o grupa halofenil, R1 este hidrogen, metil sau tiometil si R2 este o grupa alchil cu 1...6 atomi de carbon sau tiometil, prin tratarea unei tiazolidinone care are substituentul R si în pozitia 5 are un atom de hidrogen sau o grupa metil, cu o halogenura de alchil cu 1...6 atomi de carbon sau cu metildisulfura în mediu de tetrahidrofuran, în prezenta de n-butillitiu în hexan,la -70 degree C pîna la temperatura camerei.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US95170878A | 1978-10-16 | 1978-10-16 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RO82359B true RO82359B (ro) | 1983-07-30 |
| RO82359A RO82359A (ro) | 1983-08-03 |
Family
ID=25492046
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RO79105702A RO82467A (ro) | 1978-10-16 | 1979-10-15 | Procedeu pentru prepararea unor 4h-1,3-tiazin-4-one |
| RO7998944A RO78232A (ro) | 1978-10-16 | 1979-10-15 | Procedeu pentru prepararea unor 4-tiazolidinone |
| RO7998943A RO78231A (ro) | 1978-10-16 | 1979-10-15 | Procedeu pentru prepararea unor 4h-1,3-tiazin-4-one |
| RO79105701A RO82359A (ro) | 1978-10-16 | 1979-10-15 | Procedeu pentru prepararea unor 4-tiazolidinone |
Family Applications Before (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RO79105702A RO82467A (ro) | 1978-10-16 | 1979-10-15 | Procedeu pentru prepararea unor 4h-1,3-tiazin-4-one |
| RO7998944A RO78232A (ro) | 1978-10-16 | 1979-10-15 | Procedeu pentru prepararea unor 4-tiazolidinone |
| RO7998943A RO78231A (ro) | 1978-10-16 | 1979-10-15 | Procedeu pentru prepararea unor 4h-1,3-tiazin-4-one |
Country Status (28)
| Country | Link |
|---|---|
| EP (1) | EP0010420B1 (ro) |
| JP (1) | JPS5555184A (ro) |
| AR (1) | AR225154A1 (ro) |
| AT (1) | ATA670079A (ro) |
| AU (1) | AU5165479A (ro) |
| BE (1) | BE879368A (ro) |
| BR (1) | BR7906634A (ro) |
| CH (1) | CH643842A5 (ro) |
| CS (1) | CS216535B2 (ro) |
| DD (3) | DD150746A5 (ro) |
| DE (1) | DE2967188D1 (ro) |
| DK (1) | DK434779A (ro) |
| ES (2) | ES485072A0 (ro) |
| FI (1) | FI793191A7 (ro) |
| FR (1) | FR2439197B1 (ro) |
| GB (1) | GB2031892B (ro) |
| GR (1) | GR71652B (ro) |
| HU (2) | HU185844B (ro) |
| IE (1) | IE48966B1 (ro) |
| IL (1) | IL58446A (ro) |
| LU (1) | LU81779A1 (ro) |
| NZ (1) | NZ191818A (ro) |
| PH (1) | PH15765A (ro) |
| PL (2) | PL125628B1 (ro) |
| PT (2) | PT70313A (ro) |
| RO (4) | RO82467A (ro) |
| SU (1) | SU1079175A3 (ro) |
| ZA (1) | ZA795488B (ro) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4443455A (en) * | 1978-02-17 | 1984-04-17 | Imperial Chemical Industries Plc | Fungidical thiazolidinones |
| US4443454A (en) * | 1978-02-17 | 1984-04-17 | Imperial Chemical Industries Plc | Thiazolidinones |
| US4482712A (en) * | 1978-10-16 | 1984-11-13 | Eli Lilly And Company | Substituted 1-thia-3-aza-4-ones |
| GB2096993A (en) * | 1981-04-02 | 1982-10-27 | Ciba Geigy Ag | Novel thiazoline derivatives and compositions containing them and their use as pesticides |
| CA1229337A (en) * | 1982-04-02 | 1987-11-17 | Pieter T. Haken | Fungicidal heterocyclic compounds |
| JPS6061580A (ja) * | 1983-09-16 | 1985-04-09 | Zenyaku Kogyo Kk | 新規１，４−チアジン誘導体とその製造法 |
| JPS63225373A (ja) * | 1986-07-24 | 1988-09-20 | Sumitomo Pharmaceut Co Ltd | 新規チアゾリジン−４−オン誘導体およびその酸付加塩 |
| US4992455A (en) * | 1987-05-22 | 1991-02-12 | Sumitomo Pharmaceuticals Company, Limited | Thiazolidin-4-one derivatives useful for treating diseases caused by platelet activating factor |
| US5021435A (en) * | 1988-01-22 | 1991-06-04 | Sumitomo Pharmaceuticals Company, Limited | Certain pyridyl-thiazolidin-4-one having anti-ulcer activity |
| EP0481405B1 (de) * | 1990-10-17 | 1997-06-11 | Hoechst Schering AgrEvo GmbH | Pyrimidin-Derivate, Verfahren zu ihrer Herstellung sie enthaltende Mittel und ihre Verwendung als Fungizide |
| DE4243818A1 (de) * | 1992-12-23 | 1994-06-30 | Bayer Ag | 5-Aryl-1,3-thiazin-Derivate |
| JP2002517385A (ja) | 1998-06-05 | 2002-06-18 | イカゲン インク． | カリウムチャネル阻害剤 |
| US6174908B1 (en) | 1999-05-10 | 2001-01-16 | Icagen, Inc. | Potassium channel inhibitors |
| US6506751B1 (en) | 1999-11-12 | 2003-01-14 | Millennium Pharmaceuticals, Inc. | Thiazolidinone compounds useful as chemokine inhibitors |
| TWI394753B (zh) * | 2006-03-17 | 2013-05-01 | Otsuka Pharma Co Ltd | 新穎替妥牟拉（ｔｅｔｏｍｉｌａｓｔ）晶體 |
| CN117143090A (zh) * | 2023-08-14 | 2023-12-01 | 中国科学院海洋研究所 | 含呋喃杂环的4-噻唑烷酮类化合物及其制备方法与应用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2910479A (en) * | 1958-01-06 | 1959-10-27 | Ciba Pharm Prod Inc | Certain 4-pyridyl thiazoline-2-ones and process |
| CH433322A (de) * | 1964-04-16 | 1967-04-15 | Dresden Arzneimittel | Verfahren zur Herstellung von peripher gefässerweiternd wirksamen Salzen des 2-(Pyridyl-(3'))-thiazolin- 2 |
| US3574841A (en) * | 1968-03-05 | 1971-04-13 | Mobil Oil Corp | Fungicidal methods using substituted nitropyridines |
| CA962269A (en) * | 1971-05-05 | 1975-02-04 | Robert E. Grahame (Jr.) | Thiazoles, and their use as insecticides |
| GB1539726A (en) * | 1974-12-31 | 1979-01-31 | Nitidandhaprabhas O | Treatment of animals suffering from mange |
| FR2356423A1 (fr) * | 1976-07-01 | 1978-01-27 | Oeriu Simion | Derives de l'acide thiazolidinecarboxylique, leur preparation et leur application comme medicaments |
| DE2965598D1 (en) * | 1978-02-17 | 1983-07-14 | Ici Plc | Thiazolidinone derivatives, their preparation, their pesticidal compositions and processes for treating plants |
-
1979
- 1979-10-10 CS CS796885A patent/CS216535B2/cs unknown
- 1979-10-10 AU AU51654/79A patent/AU5165479A/en not_active Abandoned
- 1979-10-10 NZ NZ191818A patent/NZ191818A/xx unknown
- 1979-10-11 LU LU81779A patent/LU81779A1/fr unknown
- 1979-10-11 AR AR278464A patent/AR225154A1/es active
- 1979-10-12 PH PH23161A patent/PH15765A/en unknown
- 1979-10-12 BE BE1/9563A patent/BE879368A/fr not_active IP Right Cessation
- 1979-10-14 IL IL58446A patent/IL58446A/xx unknown
- 1979-10-15 CH CH931179A patent/CH643842A5/fr not_active IP Right Cessation
- 1979-10-15 AT AT0670079A patent/ATA670079A/de not_active Application Discontinuation
- 1979-10-15 SU SU792831951A patent/SU1079175A3/ru active
- 1979-10-15 DK DK434779A patent/DK434779A/da not_active Application Discontinuation
- 1979-10-15 IE IE1949/79A patent/IE48966B1/en unknown
- 1979-10-15 DE DE7979302215T patent/DE2967188D1/de not_active Expired
- 1979-10-15 ZA ZA00795488A patent/ZA795488B/xx unknown
- 1979-10-15 FI FI793191A patent/FI793191A7/fi not_active Application Discontinuation
- 1979-10-15 PT PT70313A patent/PT70313A/pt unknown
- 1979-10-15 HU HU79EI884A patent/HU185844B/hu unknown
- 1979-10-15 RO RO79105702A patent/RO82467A/ro unknown
- 1979-10-15 BR BR7906634A patent/BR7906634A/pt unknown
- 1979-10-15 HU HU79@@84165A patent/HU187550B/hu unknown
- 1979-10-15 FR FR7925597A patent/FR2439197B1/fr not_active Expired
- 1979-10-15 GB GB7935748A patent/GB2031892B/en not_active Expired
- 1979-10-15 EP EP79302215A patent/EP0010420B1/en not_active Expired
- 1979-10-15 RO RO7998944A patent/RO78232A/ro unknown
- 1979-10-15 RO RO7998943A patent/RO78231A/ro unknown
- 1979-10-15 PT PT70314A patent/PT70314A/pt unknown
- 1979-10-15 RO RO79105701A patent/RO82359A/ro unknown
- 1979-10-15 GR GR60266A patent/GR71652B/el unknown
- 1979-10-16 DD DD79220571A patent/DD150746A5/de unknown
- 1979-10-16 PL PL1979218994A patent/PL125628B1/pl unknown
- 1979-10-16 JP JP13410079A patent/JPS5555184A/ja active Pending
- 1979-10-16 ES ES485072A patent/ES485072A0/es active Granted
- 1979-10-16 PL PL1979231659A patent/PL127226B1/pl unknown
- 1979-10-16 DD DD79220572A patent/DD150747A5/de unknown
- 1979-10-16 DD DD79216255A patent/DD146539A5/de unknown
- 1979-10-16 ES ES485073A patent/ES485073A1/es not_active Expired
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