RO74426B - Procedeu de preparare a unor antibiotice - Google Patents

Procedeu de preparare a unor antibiotice

Info

Publication number
RO74426B
RO74426B RO84081A RO8408175A RO74426B RO 74426 B RO74426 B RO 74426B RO 84081 A RO84081 A RO 84081A RO 8408175 A RO8408175 A RO 8408175A RO 74426 B RO74426 B RO 74426B
Authority
RO
Romania
Prior art keywords
group
lower alkyl
phenylalkyl
general formula
phenyl
Prior art date
Application number
RO84081A
Other languages
English (en)
Other versions
RO74426A (ro
Inventor
Joseph John Hlavka
Panayota Bitha
Original Assignee
American Cyanamid Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Company filed Critical American Cyanamid Company
Publication of RO74426A publication Critical patent/RO74426A/ro
Publication of RO74426B publication Critical patent/RO74426B/ro

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/203Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Procedeu pentru prepararea unor antibiotice cu formula generala I: (vezi form. in desc.) în care R reprezinta o grupa aleasa dintre:(vezi form. in desc.)R1 reprezinta o grupa alchil inferior o grupa alchil inferior substituit cu halogen sau o grupa fenilalchil, R2 reprezinta o grupa alchil inferior, o grupa cicloalchil inferior, o grupa fenil, o grupa fenilalchil cu radicalul fenil monosubstituit, sau R1 si R2 împreuna reprezinta o grupa alchil inferior substituit cu halogen, o grupa alchenil, o grupacicloalchil inferior, o grupa fenil, o grupa fenil monosubstituita, o grupa fenilalchil sau o grupa fenilalchil cu radicalul fenil monosubstituit, sau R1 si R2 împreuna reprezinta o grupa tetrametilen, o grupa pentametilen sau metilen, o grupa pentamilen sau o grupa hexametilen, catacterizat prin aceea ca se aduce în reactie o amina cu formula generala II: (vezi form. in desc.) în care R are semnificatia aratata mai sus, cu o cetona cu formula generala III: R1-CO-R2 în care R1 si R2 au semnificatia aratata mai sus, în raport în greutate de 0,02 : 1, la temperatura camerei si pH=6...8, în prezenta de cianborohidrura de sodiu, în mediu de solvent inert fata de reactanti, apoi produsul de reactie este separat în mod cunoscut.
RO84081A 1974-12-05 1975-12-03 Procedeu de preparare a unor antibiotice RO74426B (ro)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US52986274A 1974-12-05 1974-12-05
US61297575A 1975-09-12 1975-09-12

Publications (2)

Publication Number Publication Date
RO74426A RO74426A (ro) 1983-04-29
RO74426B true RO74426B (ro) 1983-04-30

Family

ID=27063126

Family Applications (1)

Application Number Title Priority Date Filing Date
RO84081A RO74426B (ro) 1974-12-05 1975-12-03 Procedeu de preparare a unor antibiotice

Country Status (25)

Country Link
JP (1) JPS51125279A (ro)
AR (1) AR215581A1 (ro)
BG (1) BG26404A3 (ro)
CA (1) CA1072547A (ro)
CH (1) CH626895A5 (ro)
DD (1) DD124602A5 (ro)
DE (1) DE2553927C3 (ro)
DK (1) DK547975A (ro)
EG (1) EG12248A (ro)
FI (1) FI753415A (ro)
FR (1) FR2293212A1 (ro)
GB (1) GB1536153A (ro)
GR (1) GR58534B (ro)
HK (1) HK80779A (ro)
HU (1) HU177070B (ro)
IE (2) IE42455B1 (ro)
IL (1) IL48476A (ro)
LU (1) LU73930A1 (ro)
NL (1) NL165469C (ro)
NO (1) NO754011L (ro)
NZ (1) NZ179276A (ro)
RO (1) RO74426B (ro)
SE (1) SE7513707L (ro)
YU (1) YU304975A (ro)
ZM (1) ZM16475A1 (ro)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1087537A (en) * 1975-08-21 1980-10-14 John H. E. J. Martin Antibiotic bm123 and production thereof
US4112219A (en) * 1977-07-13 1978-09-05 American Cyanamid Company Acyl derivatives of antibiotic BM123γ

Also Published As

Publication number Publication date
ZM16475A1 (en) 1977-03-21
DE2553927A1 (de) 1976-06-16
BG26404A3 (bg) 1979-03-15
AU8659675A (en) 1977-06-02
CA1072547A (en) 1980-02-26
GR58534B (en) 1977-10-31
SE7513707L (sv) 1976-06-08
AR215581A1 (es) 1979-10-31
YU304975A (en) 1982-05-31
FR2293212B1 (ro) 1980-06-27
IL48476A0 (en) 1976-01-30
DE2553927C3 (de) 1980-07-03
FR2293212A1 (fr) 1976-07-02
NZ179276A (en) 1978-06-20
RO74426A (ro) 1983-04-29
NL165469B (nl) 1980-11-17
NL7514234A (nl) 1976-06-09
JPS51125279A (en) 1976-11-01
DD124602A5 (ro) 1977-03-02
IE42455B1 (en) 1980-08-13
DK547975A (da) 1976-06-06
HU177070B (en) 1981-07-28
NO754011L (ro) 1976-06-09
EG12248A (en) 1978-12-31
IE42455L (en) 1976-06-05
LU73930A1 (ro) 1976-07-01
CH626895A5 (en) 1981-12-15
GB1536153A (en) 1978-12-20
FI753415A (ro) 1976-06-06
DE2553927B2 (de) 1979-10-18
IE44567B1 (en) 1982-01-13
HK80779A (en) 1979-11-30
IL48476A (en) 1980-12-31
NL165469C (nl) 1981-04-15

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