PT996732E - Metodos e composicoes para sintese de acidos gordos polinsaturados de cadeia longa em plantas - Google Patents

Metodos e composicoes para sintese de acidos gordos polinsaturados de cadeia longa em plantas

Info

Publication number
PT996732E
PT996732E PT98918174T PT98918174T PT996732E PT 996732 E PT996732 E PT 996732E PT 98918174 T PT98918174 T PT 98918174T PT 98918174 T PT98918174 T PT 98918174T PT 996732 E PT996732 E PT 996732E
Authority
PT
Portugal
Prior art keywords
fad
polyesaturated
synthesis
plant
compositions
Prior art date
Application number
PT98918174T
Other languages
English (en)
Portuguese (pt)
Inventor
Pradip Mukerji
Knutzon Deborah
Huang Yung-Sheng
Thurmond Jennifer
Chaudhary Sunita
Leonard Amanda Eun-Yeong
Original Assignee
Abbott Lab
Calgene Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/834,033 external-priority patent/US6075183A/en
Priority claimed from US08/834,655 external-priority patent/US5968809A/en
Priority claimed from US08/833,610 external-priority patent/US5972664A/en
Priority claimed from US08/956,985 external-priority patent/US6051754A/en
Application filed by Abbott Lab, Calgene Llc filed Critical Abbott Lab
Publication of PT996732E publication Critical patent/PT996732E/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0071Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C12N9/0083Miscellaneous (1.14.99)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409Fatty acids
    • C12P7/6427Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
    • C12P7/6431Linoleic acids [18:2[n-6]]
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23DEDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS OR COOKING OILS
    • A23D9/00Other edible oils or fats, e.g. shortenings or cooking oils
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/158Fatty acids; Fats; Products containing oils or fats
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/115Fatty acids or derivatives thereof; Fats or oils
    • A23L33/12Fatty acids or derivatives thereof
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/20Reducing nutritive value; Dietetic products with reduced nutritive value
    • A23L33/21Addition of substantially indigestible substances, e.g. dietary fibres
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/40Complete food formulations for specific consumer groups or specific purposes, e.g. infant formula
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/02Nutrients, e.g. vitamins, minerals
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • C12N15/8247Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving modified lipid metabolism, e.g. seed oil composition
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409Fatty acids
    • C12P7/6427Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409Fatty acids
    • C12P7/6427Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
    • C12P7/6432Eicosapentaenoic acids [EPA]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409Fatty acids
    • C12P7/6427Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
    • C12P7/6434Docosahexenoic acids [DHA]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436Fatty acid esters
    • C12P7/6445Glycerides
    • C12P7/6472Glycerides containing polyunsaturated fatty acid [PUFA] residues, i.e. having two or more double bonds in their backbone
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/05Animals comprising random inserted nucleic acids (transgenic)
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Mycology (AREA)
  • Nutrition Science (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Obesity (AREA)
  • Animal Behavior & Ethology (AREA)
  • Diabetes (AREA)
  • Cell Biology (AREA)
  • Animal Husbandry (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pediatric Medicine (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
PT98918174T 1997-04-11 1998-04-10 Metodos e composicoes para sintese de acidos gordos polinsaturados de cadeia longa em plantas PT996732E (pt)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US08/834,033 US6075183A (en) 1997-04-11 1997-04-11 Methods and compositions for synthesis of long chain poly-unsaturated fatty acids in plants
US08/834,655 US5968809A (en) 1997-04-11 1997-04-11 Methods and compositions for synthesis of long chain poly-unsaturated fatty acids
US08/833,610 US5972664A (en) 1997-04-11 1997-04-11 Methods and compositions for synthesis of long chain poly-unsaturated fatty acids
US08/956,985 US6051754A (en) 1997-04-11 1997-10-24 Methods and compositions for synthesis of long chain poly-unsaturated fatty acids in plants

Publications (1)

Publication Number Publication Date
PT996732E true PT996732E (pt) 2005-11-30

Family

ID=49943076

Family Applications (2)

Application Number Title Priority Date Filing Date
PT98918174T PT996732E (pt) 1997-04-11 1998-04-10 Metodos e composicoes para sintese de acidos gordos polinsaturados de cadeia longa em plantas
PT50123835T PT1598422E (pt) 1997-04-11 1998-04-10 Métodos e composições para síntese de ácidos gordos poliinsaturados de cadeia longa em plantas

Family Applications After (1)

Application Number Title Priority Date Filing Date
PT50123835T PT1598422E (pt) 1997-04-11 1998-04-10 Métodos e composições para síntese de ácidos gordos poliinsaturados de cadeia longa em plantas

Country Status (21)

Country Link
EP (2) EP0996732B1 (OSRAM)
JP (1) JP4087460B2 (OSRAM)
CN (1) CN1253588A (OSRAM)
AT (1) ATE297994T1 (OSRAM)
AU (1) AU720677B2 (OSRAM)
BG (1) BG103798A (OSRAM)
BR (1) BR9808506A (OSRAM)
CA (1) CA2285939C (OSRAM)
DE (1) DE69830587T2 (OSRAM)
DK (1) DK0996732T3 (OSRAM)
ES (2) ES2403154T3 (OSRAM)
HU (1) HUP0001517A3 (OSRAM)
IL (1) IL132148A0 (OSRAM)
IN (1) IN1998KO00636A (OSRAM)
NO (1) NO994926L (OSRAM)
NZ (1) NZ337459A (OSRAM)
PL (1) PL336077A1 (OSRAM)
PT (2) PT996732E (OSRAM)
SK (1) SK139999A3 (OSRAM)
TR (1) TR199902474T2 (OSRAM)
WO (1) WO1998046764A1 (OSRAM)

Families Citing this family (105)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6432684B1 (en) * 1997-04-11 2002-08-13 Abbott Laboratories Human desaturase gene and uses thereof
US5968809A (en) 1997-04-11 1999-10-19 Abbot Laboratories Methods and compositions for synthesis of long chain poly-unsaturated fatty acids
US6566583B1 (en) 1997-06-04 2003-05-20 Daniel Facciotti Schizochytrium PKS genes
GB9724783D0 (en) 1997-11-24 1998-01-21 Inst Arable Crops Research Novel polypeptides
US6838594B1 (en) 1998-03-20 2005-01-04 E. I. Du Pont De Nemours And Company Limnanthes oil genes
NZ505988A (en) * 1998-03-20 2003-10-31 Edgar B Cahoon Delta-5 acyl-CoA desaturase and fatty acyl-CoA elongase and subsequent recombinant methods to produce seed oil comprising destaurated fatty acid
ATE372387T1 (de) 1998-06-12 2007-09-15 Calgene Llc Polyungesättigte fettsäuren in pflanzen
DE19836339B4 (de) 1998-08-11 2011-12-22 N.V. Nutricia Kohlenhydratmischung
WO2000020602A2 (en) * 1998-10-05 2000-04-13 Abbott Laboratories Delta 6 and delta 12 desaturases and modified fatty acid biosynthesis and products produced therefrom
US8791327B2 (en) 1998-12-07 2014-07-29 Washington State University Research Foundation Desaturases and methods of using them for synthesis of polyunsaturated fatty acids
CA2791961A1 (en) * 1998-12-07 2000-06-15 Washington State University Research Foundation Desaturases and methods of using them for synthesis of polyunsaturated fatty acids
US6825017B1 (en) 1998-12-07 2004-11-30 Washington State University Research Foundation Desaturases and methods of using them for synthesis of polyunsaturated fatty acids
US7217856B2 (en) 1999-01-14 2007-05-15 Martek Biosciences Corporation PUFA polyketide synthase systems and uses thereof
US7247461B2 (en) 1999-01-14 2007-07-24 Martek Biosciences Corporation Nucleic acid molecule encoding ORFA of a PUFA polyketide synthase system and uses thereof
US7211418B2 (en) 1999-01-14 2007-05-01 Martek Biosciences Corporation PUFA polyketide synthase systems and uses thereof
US7271315B2 (en) 1999-01-14 2007-09-18 Martek Biosciences Corporation PUFA polyketide synthase systems and uses thereof
US8003772B2 (en) 1999-01-14 2011-08-23 Martek Biosciences Corporation Chimeric PUFA polyketide synthase systems and uses thereof
DE50013231D1 (de) * 1999-06-07 2006-09-07 Basf Plant Science Gmbh Delta6-acetylenase und delta6-desaturase aus ceratodon purpureus
DE10030976A1 (de) 2000-06-30 2002-01-10 Basf Ag DELTA6-Desaturasegene exprimierende Pflanzen und PUFAS enthaltende Öle aus diesen Pflanzen und ein Verfahren zur Herstellung ungesättigter Fettsäuren
CA2378423A1 (en) * 1999-07-06 2001-01-11 Basf Plant Science Gmbh Plants expressing .delta.6-desaturase genes and oils from these plants containing pufas and method for producing unsaturated fatty acids
AU6091600A (en) * 1999-07-12 2001-01-30 Ohio University Mammalian cells expressing desaturases and elongases
EP1244472B1 (en) * 1999-12-23 2005-06-08 Adisseo France S.A.S. Particulate vitamin composition
CZ20022502A3 (cs) * 2000-02-09 2002-10-16 Basf Aktiengesellschaft Elongázový gen a způsob přípravy polynenasycených mastných kyselin
DK1322752T3 (da) 2000-09-28 2010-07-19 Bioriginal Food & Science Corp FAD4, FAD5, FAD5-2, og FAD6-medlemmer af fedtsyredesaturasefamilien og anvendelser deraf
DE10102338A1 (de) * 2001-01-19 2002-07-25 Basf Plant Science Gmbh Verfahren zur Expression von Biosynthesegenen in pflanzlichen Samen unter Verwendung von neuen multiplen Expressionskonstrukten
US6635451B2 (en) * 2001-01-25 2003-10-21 Abbott Laboratories Desaturase genes and uses thereof
GB0107510D0 (en) 2001-03-26 2001-05-16 Univ Bristol New elongase gene and a process for the production of -9-polyunsaturated fatty acids
US7045683B2 (en) * 2001-05-04 2006-05-16 Abbott Laboratories Δ4-desaturase genes and uses thereof
US7211656B2 (en) 2002-01-30 2007-05-01 Abbott Laboratories Desaturase genes, enzymes encoded thereby, and uses thereof
CA2474163C (en) 2002-01-30 2012-04-17 Basf Plant Science Gmbh Novel elongase gene and method for producing polyunsaturated fatty acids
GB2385852A (en) 2002-02-27 2003-09-03 Rothamsted Ex Station Delta 6-desaturases from Primulaceae
DE10219203A1 (de) 2002-04-29 2003-11-13 Basf Plant Science Gmbh Verfahren zur Herstellung mehrfach ungesättigter Fettsäuren in Pflanzen
FR2844142B1 (fr) 2002-09-11 2007-08-17 Bayer Cropscience Sa Plantes transformees a biosynthese de prenylquinones amelioree
FR2848570B1 (fr) 2002-12-12 2005-04-01 Bayer Cropscience Sa Cassette d'expression codant pour une 5-enol pyruvylshikimate-3-phosphate synthase (epsps) et plantes tolerantes aux herbicides la contenant
US7714185B2 (en) 2002-12-19 2010-05-11 University Of Bristol Method for the production of polyunsaturated fatty acids
US20040172682A1 (en) * 2003-02-12 2004-09-02 Kinney Anthony J. Production of very long chain polyunsaturated fatty acids in oilseed plants
US8084074B2 (en) 2003-02-12 2011-12-27 E. I. Du Pont De Nemours And Company Production of very long chain polyunsaturated fatty acids in oil seed plants
BRPI0407138A (pt) 2003-02-27 2006-01-10 Basf Plant Science Gmbh Sequência de ácido nucleico isolada, sequência de aminoácido, construção de gene, vetor, organismo transgênico não humano, processo para produzir ácidos graxos poliinsaturados, óleo, lipìdeo, ou um ácido graxo poliinsaturado ou uma fração dos mesmos, composições de óleo, de lipìdeos, ou de ácido graxo, e, uso do óleo, lipìdeos ou ácidos graxos ou de composições de óleo, de lipìdeos ou de ácido graxo
EP2390313B1 (de) 2003-03-31 2016-05-11 University Of Bristol Neue pflanzliche Acyltransferase spezifisch für langkettige mehrfach ungesättigte Fettsäuren
EP1613744B1 (de) 2003-04-08 2015-09-09 BASF Plant Science GmbH Delta-4-desaturasen aus euglena gracilis, exprimierende pflanzen und pufa enthaltende öle
US11952581B2 (en) 2003-08-01 2024-04-09 Basf Plant Science Gmbh Process for the production of polyunsaturated fatty acids in transgenic organisms
EP2166067B1 (de) 2003-08-01 2015-07-01 BASF Plant Science GmbH Verfahren zur Herstellung mehrfach ungesättigter Fettsäuren in transgenen Organismen
PT1656449E (pt) 2003-08-21 2009-07-27 Monsanto Technology Llc Dessaturases dos ácidos gordos a partir de prímulas
WO2005047480A2 (en) * 2003-11-12 2005-05-26 E.I. Dupont De Nemours And Company Delta-15 desaturases suitable for altering levels of polyunsaturated fatty acids in oleaginous plants and yeast
WO2005059130A1 (ja) * 2003-12-17 2005-06-30 Suntory Limited アラキドン酸を含有する植物体およびその利用
US9458436B2 (en) 2004-02-27 2016-10-04 Basf Plant Science Gmbh Method for producing polyunsaturated fatty acids in transgenic plants
EP1720988B1 (de) 2004-02-27 2011-10-12 BASF Plant Science GmbH Verfahren zur herstellung von ungesättigten omega-3-fettsäuren in transgenen organismen
WO2005102310A1 (en) 2004-04-16 2005-11-03 Monsanto Technology Llc Expression of fatty acid desaturases in corn
DK1756280T3 (en) 2004-04-22 2015-02-02 Commw Scient Ind Res Org SYNTHESIS OF CHAIN, polyunsaturated fatty acids BY RECOMBINANT CELLS
ES2715640T3 (es) * 2004-04-22 2019-06-05 Commw Scient Ind Res Org Síntesis de ácidos grasos poliinsaturados de cadena larga por células recombinantes
EP1597978A1 (en) 2004-05-17 2005-11-23 Nutricia N.V. Synergism of GOS and polyfructose
US20050266051A1 (en) * 2004-05-27 2005-12-01 The Procter & Gamble Company Pet food compositions and methods
PT1766023E (pt) 2004-06-04 2010-12-09 Fluxome Sciences As Células metabolicamente manipuladas para a produção de ácidos gordos poliinsaturados
US8252769B2 (en) 2004-06-22 2012-08-28 N. V. Nutricia Intestinal barrier integrity
US7550651B2 (en) 2004-06-25 2009-06-23 E.I. Du Pont De Nemours And Company Delta-8 desaturase and its use in making polyunsaturated fatty acids
EP1634599A1 (en) 2004-08-20 2006-03-15 N.V. Nutricia Iimmune stimulatory infant nutrition
EP2194140A2 (en) 2005-03-02 2010-06-09 Metanomics GmbH Process for the production of fine chemicals
CN100339481C (zh) * 2005-03-17 2007-09-26 东北师范大学 应用基因沉默技术提高大豆和花生的种子油酸含量的方法
DE102005013779A1 (de) 2005-03-22 2006-09-28 Basf Plant Science Gmbh Verfahren zur Herstellung von mehrfach ungesättigten C20- und C22-Fettsäuren mit mindestens vier Doppelbindungen in transgenen Pflanzen
WO2006127789A2 (en) * 2005-05-23 2006-11-30 Arcadia Biosciences, Inc. Safflower with elevated gamma-linolenic acid
CN1302110C (zh) * 2005-06-23 2007-02-28 复旦大学 水稻Osfad8编码序列及其应用
DE102005038036A1 (de) 2005-08-09 2007-02-15 Basf Plant Science Gmbh Verfahren zur Herstellung von Arachidonsäure und/oder Eicosapentaensäure in transgenen Nutzpflanzen
GB2431158A (en) 2005-10-13 2007-04-18 Rothamsted Res Ltd Process for the production of arachidonic and/or eicosapentaenoic acid
DE102005052551A1 (de) 2005-11-02 2007-05-16 Rothamsted Res Harpenden Verfahren zur Herstellung von y-Linolensäure und/oder Stearidonsäure in transgenen Brassicaceae und Linaceae
DK1951866T3 (da) 2005-11-23 2014-10-27 Du Pont Delta-9-elongaser og anvendelse heraf til fremstilling af flerumættede fedtsyrer
GB0603160D0 (en) 2006-02-16 2006-03-29 Rothamsted Res Ltd Nucleic acid
AR059376A1 (es) 2006-02-21 2008-03-26 Basf Plant Science Gmbh Procedimiento para la produccion de acidos grasos poliinsaturados
WO2007106905A2 (en) 2006-03-15 2007-09-20 Martek Biosciences Corporation Polyunsaturated fatty acid production in heterologous organisms using pufa polyketide synthase systems
US8629195B2 (en) 2006-04-08 2014-01-14 Bayer Materialscience Ag Production of polyurethane foams
US7943823B2 (en) 2006-04-28 2011-05-17 E.I. Du Pont De Nemours And Company Delta-8 desaturase and its use in making polyunsaturated fatty acids
US7695950B2 (en) 2006-05-17 2010-04-13 E. I. Du Pont De Nemours And Company Δ5 desaturase and its use in making polyunsaturated fatty acids
US7678560B2 (en) 2006-05-17 2010-03-16 E.I. Du Pont De Nemours And Company Δ 5 desaturase and its use in making polyunsaturated fatty acids
WO2008022963A2 (en) 2006-08-24 2008-02-28 Basf Plant Science Gmbh Isolation and characterization of a novel pythium omega 3 desaturase with specificity to all omega 6 fatty acids longer than 18 carbon chains
AU2007291937B2 (en) 2006-08-29 2014-05-15 Commonwealth Scientific And Industrial Research Organisation Synthesis of fatty acids
ES2531391T3 (es) 2006-10-06 2015-03-13 Basf Plant Science Gmbh Delta-5 desaturasas y procedimiento para la preparación de ácidos grasos poliinsaturados en organismos transgénicos no humanos
US7863502B2 (en) 2006-10-23 2011-01-04 E.I. Dupont De Nemours And Company Delta-8 desaturases and their use in making polyunsaturated fatty acids
US8188338B2 (en) 2007-04-10 2012-05-29 E. I. Du Pont De Nemours And Company Delta-8 desaturases and their use in making polyunsaturated fatty acids
US8119860B2 (en) 2007-04-16 2012-02-21 E. I. Du Pont De Nemours And Company Delta-9 elongases and their use in making polyunsaturated fatty acids
US7943365B2 (en) * 2007-05-03 2011-05-17 E.I. Du Pont De Nemours And Company Δ-5 desaturases and their use in making polyunsaturated fatty acids
CA2695112A1 (en) 2007-07-31 2009-02-05 Basf Plant Science Gmbh Elongases and processes for the production of polyunsaturated fatty acids in transgenic organisms
WO2009077478A2 (en) 2007-12-14 2009-06-25 Basf Plant Science Gmbh Promoters from brassica napus for seed specific gene expression
EP2234475A1 (en) 2007-12-20 2010-10-06 Dow Agrosciences LLC Low saturated-fat sunflower and associated methods
WO2009133145A1 (en) 2008-04-30 2009-11-05 Basf Plant Science Gmbh Desaturase and method for the production of polyunsaturated fatty acids in transgenic organisms
EP3431607A3 (en) 2008-07-01 2019-03-06 BASF Plant Science GmbH Promoters from brassica napus for seed specific gene expression
EP2331695B1 (en) 2008-08-26 2014-07-23 BASF Plant Science GmbH Nucleic acids encoding desaturases and modified plant oil
CN113957054B (zh) 2008-11-18 2024-07-16 联邦科学技术研究组织 产生ω-3脂肪酸的酶和方法
US8822662B2 (en) 2008-12-12 2014-09-02 Basf Plant Science Company Gmbh Desaturases and process for the production of polyunsaturated fatty acids in transgenic organisms
AR074941A1 (es) 2009-01-07 2011-02-23 Bayer Cropscience Sa Plantas transplastomicas exentas de marcador de seleccion
AU2010226440B2 (en) 2009-03-19 2015-08-20 Dsm Ip Assets B.V. Polyunsaturated fatty acid synthase nucleic acid molecules and polypeptides, compositions, and methods of making and uses thereof
WO2010130725A1 (en) 2009-05-13 2010-11-18 Basf Plant Science Company Gmbh Acyltransferases and uses thereof in fatty acid production
US11236351B2 (en) 2010-05-17 2022-02-01 Dow Agrosciences Llc Production of DHA and other LC PUFAs in plants
CA2804925A1 (en) 2010-06-25 2011-12-29 Basf Plant Science Company Gmbh Acyltransferases from thraustochytrium species and uses thereof in fatty acid production
EP2609202A1 (en) 2010-08-26 2013-07-03 E.I. Du Pont De Nemours And Company Mutant hpgg motif and hdash motif delta-5 desaturases and their use in making polyunsaturated fatty acids
TW201307553A (zh) * 2011-07-26 2013-02-16 Dow Agrosciences Llc 在植物中生產二十二碳六烯酸(dha)及其他長鏈多元不飽和脂肪酸(lc-pufa)之技術
JP2015500639A (ja) * 2011-11-29 2015-01-08 ディグニティ サイエンシス リミテッド 20−炭素脂肪酸を含む組成物ならびにその製造方法および使用方法
BR112014025265A2 (pt) 2012-04-12 2017-07-11 Rothamsted Res Ltd produção de ácidos graxos poli-insaturados ômega-3 de cadeia longa
SG10201810439SA (en) 2012-06-15 2018-12-28 Commw Scient Ind Res Org Production of long chain polyunsaturated fatty acids in plant cells
BR112014031784A2 (pt) 2012-06-19 2019-10-01 Du Pont acil-coa:lisofosfatidilcolina aciltransferases mutantes
GB201217524D0 (en) 2012-10-01 2012-11-14 Rothamsted Res Ltd Recombinant organisms
PH12016501194B1 (en) 2013-12-18 2022-04-22 Commw Scient Ind Res Org Lipid comprising long chain polyunsaturated fatty acids
SG11201610596PA (en) 2014-06-27 2017-01-27 Commw Scient Ind Res Org Lipid comprising docosapentaenoic acid
CN104839353A (zh) * 2015-04-30 2015-08-19 安庆市顺民粮油贸易有限公司 一种幼儿保健食用油及其制作方法
CN105400838B (zh) * 2015-12-30 2019-09-20 厦门金达威生物科技有限公司 一种生物酶催化制备磷脂型dha的方法
CN108410916A (zh) * 2018-05-30 2018-08-17 湖北福星生物科技有限公司 花生四烯酸油脂的生产方法
CN111317068A (zh) * 2020-01-15 2020-06-23 广州市优百特饲料科技有限公司 饲用opo母乳结构脂及其制备方法及其应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5614393A (en) * 1991-10-10 1997-03-25 Rhone-Poulenc Agrochimie Production of γ-linolenic acid by a Δ6-desaturase
PH31293A (en) * 1991-10-10 1998-07-06 Rhone Poulenc Agrochimie Production of y-linolenic acid by a delta6-desaturage.
EP0561569B1 (en) * 1992-03-13 2003-06-11 Agrigenetics, Inc. Modification of vegetable oils using desaturase
WO1994011516A1 (en) * 1992-11-17 1994-05-26 E.I. Du Pont De Nemours And Company Genes for microsomal delta-12 fatty acid desaturases and related enzymes from plants
US7205457B1 (en) * 1993-02-05 2007-04-17 Monsanto Technology Llc Altered linolenic and linoleic acid content in plants
US6310194B1 (en) * 1994-09-26 2001-10-30 Carnegie Institution Of Washington Plant fatty acid hydroxylases

Also Published As

Publication number Publication date
JP2001527395A (ja) 2001-12-25
BR9808506A (pt) 2000-05-23
NZ337459A (en) 2000-07-28
EP1598422A3 (en) 2005-12-28
CA2285939C (en) 2010-06-15
IN1998KO00636A (OSRAM) 2005-03-18
ES2403154T3 (es) 2013-05-14
AU720677B2 (en) 2000-06-08
PL336077A1 (en) 2000-06-05
DK0996732T3 (da) 2005-10-17
MX9909328A (es) 2000-04-30
DE69830587D1 (de) 2005-07-21
ES2245030T3 (es) 2005-12-16
NO994926D0 (no) 1999-10-08
EP1598422A2 (en) 2005-11-23
ATE297994T1 (de) 2005-07-15
WO1998046764A1 (en) 1998-10-22
PT1598422E (pt) 2013-04-03
EP0996732B1 (en) 2005-06-15
BG103798A (en) 2000-05-31
CA2285939A1 (en) 1998-10-22
EP1598422B1 (en) 2013-01-02
DE69830587T2 (de) 2006-05-24
SK139999A3 (en) 2000-05-16
EP0996732A1 (en) 2000-05-03
IL132148A0 (en) 2001-03-19
CN1253588A (zh) 2000-05-17
HUP0001517A3 (en) 2002-04-29
HUP0001517A1 (hu) 2000-08-28
TR199902474T2 (xx) 2000-02-21
AU7114798A (en) 1998-11-11
NO994926L (no) 1999-11-30
JP4087460B2 (ja) 2008-05-21

Similar Documents

Publication Publication Date Title
PT996732E (pt) Metodos e composicoes para sintese de acidos gordos polinsaturados de cadeia longa em plantas
IL162991A (en) Isolated nucleic acid sequences which encode polypeptide having delta-6-desaturase activity, amino acid sequences, gene constructs, vectors, transgenic non human organisms and methods for production of pufa
AU2003224236A1 (en) Transgenic plants expressing enzymes involved in fatty acid biosynthesis
WO2005047479A3 (en) Delta-15 desaturases suitable for altering levels of polyunsaturated fatty acids in oilseed plants and oleaginous yeast
DE60322515D1 (de) Desaturasegene, von diesen codierte enzyme und verwendungen dafür
ATE353952T1 (de) Desaturasen und verfahren ihrer anwendung zur synthese von mehrfach ungesättigten fettsäuren
AR021789A1 (es) Genes de la elongasa y usos de los mismos.
WO2007136671A3 (en) Delta5 desaturase and its use in making polyunsaturated fatty acids
WO2005047485A3 (en) Delta12 desaturases suitable for altering levels of polyunsaturated fatty acids in oleaginous yeast
NO991635L (no) Farmas°ytisk preparat omfattende eikospentaensyre og/eller stearidonsyre
WO2007136646A3 (en) Delta5 desaturase and its use in making polyunsaturated fatty acids
GEP20012558B (en) Nuclear-Encoded Transcription System in Plastids of Higher Plants
DK0975766T3 (da) Fremgangsmåder og sammensætninger til syntese af langkædede polyumættede fedtsyrer
MXPA03006663A (es) Genes de desaturasa y usos de los mismos.
BR0011400A (pt) Sequência de ácido nucleico isolada, sequência de aminoácidos, cassete de expressão, vetor, organismo, planta transgênica, processos para preparar ácidos graxos insaturados, e para preparar triglicerìdeos, proteìna, ácido graxo insaturado, triglicerìdeo, e, uso de uma sequência de ácidos nucleicos, de ácidos graxos insaturados ou triglicerìdeos com um conteúdo aumentado de ácidos graxos insaturados, e de proteìnas
AU1844702A (en) Fad4, fad5, fad5-2, and fad6, novel fatty acid desaturase family members and uses thereof
IL132149A0 (en) Methods and compositions for synthesis of long chain polyunsaturated fatty acids
DE50312241D1 (de) Verfahren zur herstellung mehrfach ungesättigter f
ATE542892T1 (de) Delta-17-desaturasen und ihre verwendung bei der herstellung von mehrfach ungesättigten fettsäuren
WO2008063340A3 (en) Delta-8 desaturases and their use in making polyunsaturated fatty acids
EE200200115A (et) Taimedest saadav rasvhappe-desaturaas-geen
AR017171A1 (es) Una desaturasa de acido graso, una celula huesped para expresarla, el uso de dicha celula huesped, un acido nucleico aislado que la codifica, un aceite ofraccion del mismo obtenido mediante dicha celula y una composicion farmaceutica, una formula nutricional tal como una formula para bebes, un suple