PT98955A - Processo de preparacao de composicoes quimicas secas estabilizadas contendo um sal de adicao de acido soluvel em agua de um composto basico pouco soluvel, e de aumento da insensibilidade de um procedimento de granulacao - Google Patents
Processo de preparacao de composicoes quimicas secas estabilizadas contendo um sal de adicao de acido soluvel em agua de um composto basico pouco soluvel, e de aumento da insensibilidade de um procedimento de granulacaoInfo
- Publication number
- PT98955A PT98955A PT98955A PT9895591A PT98955A PT 98955 A PT98955 A PT 98955A PT 98955 A PT98955 A PT 98955A PT 9895591 A PT9895591 A PT 9895591A PT 98955 A PT98955 A PT 98955A
- Authority
- PT
- Portugal
- Prior art keywords
- compositions containing
- basic compound
- insensibility
- soluable
- increasing
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1611—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Lubricants (AREA)
- Developing Agents For Electrophotography (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US58185990A | 1990-09-13 | 1990-09-13 |
Publications (2)
Publication Number | Publication Date |
---|---|
PT98955A true PT98955A (pt) | 1992-08-31 |
PT98955B PT98955B (pt) | 1999-02-26 |
Family
ID=24326864
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT98955A PT98955B (pt) | 1990-09-13 | 1991-09-12 | Processo de preparacao de composicoes quimicas secas estabilizadas contendo um sal de adicao de acido soluvel em agua de um composto basico pouco soluvel, e de aumento da insensibilidade de um procedimento de granulacao |
Country Status (14)
Country | Link |
---|---|
EP (1) | EP0475482B1 (pt) |
JP (1) | JP3153577B2 (pt) |
KR (1) | KR100196209B1 (pt) |
AT (1) | ATE112491T1 (pt) |
AU (1) | AU643920B2 (pt) |
CA (1) | CA2049811C (pt) |
DE (1) | DE69104453T2 (pt) |
DK (1) | DK0475482T3 (pt) |
ES (1) | ES2064887T3 (pt) |
FI (1) | FI104361B (pt) |
IE (1) | IE65274B1 (pt) |
NZ (1) | NZ239753A (pt) |
PT (1) | PT98955B (pt) |
ZA (1) | ZA916661B (pt) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1994022445A2 (en) * | 1993-03-26 | 1994-10-13 | Merkus Franciscus W H M | Pharmaceutical compositions for intranasal administration of dihydroergotamine, apomorphine and morphine |
AU750361B2 (en) * | 1997-03-26 | 2002-07-18 | Franciscus W.H.M. Merkus | Nasal melatonin composition |
GB0001621D0 (en) | 2000-01-26 | 2000-03-15 | Astrazeneca Ab | Pharmaceutical compositions |
US6691057B2 (en) | 2001-02-26 | 2004-02-10 | L.U.M. Gesellschaft Fur Labor- Umweltdiagnostic & Medizintechnik Mbh | Method and device for accelerated stability analysis |
US7407955B2 (en) | 2002-08-21 | 2008-08-05 | Boehringer Ingelheim Pharma Gmbh & Co., Kg | 8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions |
DE102004054054A1 (de) | 2004-11-05 | 2006-05-11 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Verfahren zur Herstellung chiraler 8-(3-Amino-piperidin-1-yl)-xanthine |
CA2491665A1 (fr) * | 2004-12-24 | 2006-06-24 | Louis Cartilier | Formulation de comprime pour liberation soutenue de principe actif |
NO347644B1 (no) | 2006-05-04 | 2024-02-12 | Boehringer Ingelheim Int | Polymorfer |
EP1852108A1 (en) | 2006-05-04 | 2007-11-07 | Boehringer Ingelheim Pharma GmbH & Co.KG | DPP IV inhibitor formulations |
PE20080251A1 (es) | 2006-05-04 | 2008-04-25 | Boehringer Ingelheim Int | Usos de inhibidores de dpp iv |
AR071175A1 (es) | 2008-04-03 | 2010-06-02 | Boehringer Ingelheim Int | Composicion farmaceutica que comprende un inhibidor de la dipeptidil-peptidasa-4 (dpp4) y un farmaco acompanante |
KR20200118243A (ko) | 2008-08-06 | 2020-10-14 | 베링거 인겔하임 인터내셔날 게엠베하 | 메트포르민 요법이 부적합한 환자에서의 당뇨병 치료 |
UY32030A (es) | 2008-08-06 | 2010-03-26 | Boehringer Ingelheim Int | "tratamiento para diabetes en pacientes inapropiados para terapia con metformina" |
US20200155558A1 (en) | 2018-11-20 | 2020-05-21 | Boehringer Ingelheim International Gmbh | Treatment for diabetes in patients with insufficient glycemic control despite therapy with an oral antidiabetic drug |
US8865729B2 (en) | 2008-12-23 | 2014-10-21 | Boehringer Ingelheim International Gmbh | Salt forms of a xanthine compound |
TW201036975A (en) | 2009-01-07 | 2010-10-16 | Boehringer Ingelheim Int | Treatment for diabetes in patients with inadequate glycemic control despite metformin therapy |
AU2010323068B2 (en) | 2009-11-27 | 2015-09-03 | Boehringer Ingelheim International Gmbh | Treatment of genotyped diabetic patients with DPP-IV inhibitors such as linagliptin |
WO2011138421A1 (en) | 2010-05-05 | 2011-11-10 | Boehringer Ingelheim International Gmbh | Combination therapy |
KR20190050871A (ko) | 2010-06-24 | 2019-05-13 | 베링거 인겔하임 인터내셔날 게엠베하 | 당뇨병 요법 |
AR083878A1 (es) | 2010-11-15 | 2013-03-27 | Boehringer Ingelheim Int | Terapia antidiabetica vasoprotectora y cardioprotectora, linagliptina, metodo de tratamiento |
KR101985384B1 (ko) | 2011-07-15 | 2019-06-03 | 베링거 인겔하임 인터내셔날 게엠베하 | 치환된 퀴나졸린, 이의 제조 및 약제학적 조성물에서의 이의 용도 |
US9555001B2 (en) | 2012-03-07 | 2017-01-31 | Boehringer Ingelheim International Gmbh | Pharmaceutical composition and uses thereof |
EP2849755A1 (en) | 2012-05-14 | 2015-03-25 | Boehringer Ingelheim International GmbH | A xanthine derivative as dpp -4 inhibitor for use in the treatment of podocytes related disorders and/or nephrotic syndrome |
WO2013174767A1 (en) | 2012-05-24 | 2013-11-28 | Boehringer Ingelheim International Gmbh | A xanthine derivative as dpp -4 inhibitor for use in modifying food intake and regulating food preference |
WO2015128453A1 (en) | 2014-02-28 | 2015-09-03 | Boehringer Ingelheim International Gmbh | Medical use of a dpp-4 inhibitor |
RU2609198C1 (ru) * | 2016-01-25 | 2017-01-30 | Закрытое Акционерное Общество "БИОКОМ" | Твердая лекарственная форма имипрамина немедленного высвобождения и способ ее получения |
US10155000B2 (en) | 2016-06-10 | 2018-12-18 | Boehringer Ingelheim International Gmbh | Medical use of pharmaceutical combination or composition |
KR102416406B1 (ko) * | 2019-09-24 | 2022-07-04 | 주식회사 종근당 | 티카그렐러의 산 부가염을 포함하는 안정화된 약학 조성물 |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2554736A (en) | 1951-05-29 | Tertiary aminoalkyl-iminodibenzyls | ||
US2018410A (en) | 1933-12-11 | 1935-10-22 | Victor Chemical Works | Dentifrice preparation |
US2287699A (en) | 1940-02-15 | 1942-06-23 | Monsanto Chemicals | Stabilized dicalcium phosphate |
US3012852A (en) | 1956-06-06 | 1961-12-12 | Monsanto Chemicals | Stabilized calcium phosphates and process therefor |
DE1277222B (de) | 1965-12-22 | 1968-09-12 | Knapsack Ag | Verfahren zur Stabilisierung von Dicalciumphosphatdihydrat |
NL129434C (pt) | 1966-03-12 | |||
US4128641A (en) | 1975-07-31 | 1978-12-05 | Hzi Research Center Inc. | Tetracyclic psychotropic drug |
DE2648061C2 (de) | 1976-10-23 | 1982-11-04 | Hoechst Ag, 6000 Frankfurt | Verfahren zum Stabilisieren von Di-calciumhydrogenphosphatdihydrat |
DE2741513A1 (de) | 1977-09-15 | 1979-03-22 | Benckiser Gmbh Joh A | Verfahren zum stabilisieren von calciumhydrogenphosphat-dihydrat gegen hydrolyse |
IE52274B1 (en) | 1980-12-12 | 1987-09-02 | Stauffer Chemical Co | A process of compacting fine particles of calcium phosphate and the compacts obtained thereby |
SE8103843L (sv) * | 1981-06-18 | 1982-12-19 | Astra Laekemedel Ab | Farmaceutisk mixtur |
US4743450A (en) | 1987-02-24 | 1988-05-10 | Warner-Lambert Company | Stabilized compositions |
US5004651A (en) | 1989-01-24 | 1991-04-02 | Abbott Laboratories | Stabilizing system for solid dosage forms |
GB8920693D0 (en) * | 1989-09-13 | 1989-10-25 | Nicholas Kiwi Pty Ltd | Non-effervescent ibuprofen compositions |
-
1991
- 1991-08-13 ES ES91202070T patent/ES2064887T3/es not_active Expired - Lifetime
- 1991-08-13 DE DE69104453T patent/DE69104453T2/de not_active Expired - Lifetime
- 1991-08-13 DK DK91202070.8T patent/DK0475482T3/da active
- 1991-08-13 EP EP91202070A patent/EP0475482B1/en not_active Expired - Lifetime
- 1991-08-13 AT AT91202070T patent/ATE112491T1/de not_active IP Right Cessation
- 1991-08-22 ZA ZA916661A patent/ZA916661B/xx unknown
- 1991-08-23 CA CA002049811A patent/CA2049811C/en not_active Expired - Fee Related
- 1991-08-27 AU AU83416/91A patent/AU643920B2/en not_active Expired
- 1991-08-29 IE IE305491A patent/IE65274B1/en not_active IP Right Cessation
- 1991-09-03 FI FI914147A patent/FI104361B/fi not_active IP Right Cessation
- 1991-09-11 NZ NZ239753A patent/NZ239753A/en not_active IP Right Cessation
- 1991-09-12 JP JP23322491A patent/JP3153577B2/ja not_active Expired - Fee Related
- 1991-09-12 PT PT98955A patent/PT98955B/pt not_active IP Right Cessation
- 1991-09-12 KR KR1019910015896A patent/KR100196209B1/ko not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
ES2064887T3 (es) | 1995-02-01 |
FI914147A0 (fi) | 1991-09-03 |
IE913054A1 (en) | 1992-02-25 |
PT98955B (pt) | 1999-02-26 |
AU643920B2 (en) | 1993-11-25 |
KR100196209B1 (ko) | 1999-06-15 |
AU8341691A (en) | 1992-03-19 |
EP0475482A1 (en) | 1992-03-18 |
CA2049811A1 (en) | 1992-03-14 |
FI104361B (fi) | 2000-01-14 |
NZ239753A (en) | 1992-10-28 |
DK0475482T3 (da) | 1995-04-03 |
EP0475482B1 (en) | 1994-10-05 |
DE69104453D1 (de) | 1994-11-10 |
KR920005978A (ko) | 1992-04-27 |
IE65274B1 (en) | 1995-10-18 |
ZA916661B (en) | 1992-06-24 |
FI914147A (fi) | 1992-03-14 |
DE69104453T2 (de) | 1995-03-16 |
ATE112491T1 (de) | 1994-10-15 |
CA2049811C (en) | 2002-11-05 |
JPH0578236A (ja) | 1993-03-30 |
JP3153577B2 (ja) | 2001-04-09 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
BB1A | Laying open of patent application |
Effective date: 19920511 |
|
FG3A | Patent granted, date of granting |
Effective date: 19981109 |
|
PC4A | Transfer of assignment |
Owner name: N.V. ORGANON, NL Effective date: 20061124 |
|
PD4A | Change of proprietorship |
Owner name: AKZO NOBEL N.V., NL Effective date: 20061124 |
|
PC4A | Transfer of assignment |
Owner name: MSD OSS B.V., NL Effective date: 20111209 |
|
PC4A | Transfer of assignment |
Owner name: ORGANON BIOSCIENCES NEDERLAND B.V., NL Effective date: 20130517 |
|
PC4A | Transfer of assignment |
Owner name: MERCK SHARP & DOHME B.V., NL Effective date: 20130604 |
|
MM4A | Annulment/lapse due to non-payment of fees, searched and examined patent |
Free format text: MAXIMUM VALIDITY LIMIT REACHED Effective date: 20131111 |