PT96135A - Processo para a preparacao de analogos peptido de somatostatina tendo treonina na sexta posicao - Google Patents
Processo para a preparacao de analogos peptido de somatostatina tendo treonina na sexta posicaoInfo
- Publication number
- PT96135A PT96135A PT96135A PT9613590A PT96135A PT 96135 A PT96135 A PT 96135A PT 96135 A PT96135 A PT 96135A PT 9613590 A PT9613590 A PT 9613590A PT 96135 A PT96135 A PT 96135A
- Authority
- PT
- Portugal
- Prior art keywords
- alkyl
- treonine
- preparing
- peptide analogues
- phenylalkyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/655—Somatostatins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/655—Somatostatins
- C07K14/6555—Somatostatins at least 1 amino acid in D-form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/16—Somatostatin; related peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/26—Containing cys-cys disulfide bridge between nonadjacent cysteine residues
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Endocrinology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Diabetes (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US44787689A | 1989-12-08 | 1989-12-08 |
Publications (2)
Publication Number | Publication Date |
---|---|
PT96135A true PT96135A (pt) | 1991-09-30 |
PT96135B PT96135B (pt) | 1998-04-30 |
Family
ID=23778103
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT96135A PT96135B (pt) | 1989-12-08 | 1990-12-07 | Processo para a preparacao de analogos peptido de somatostatina tendo treonina na sexta posicao |
Country Status (14)
Country | Link |
---|---|
US (1) | US5506339A (pt) |
EP (1) | EP0457888B1 (pt) |
JP (1) | JP2925321B2 (pt) |
KR (1) | KR920702854A (pt) |
AT (1) | ATE140237T1 (pt) |
CA (1) | CA2046594A1 (pt) |
DE (1) | DE69027767T2 (pt) |
DK (1) | DK0457888T3 (pt) |
ES (1) | ES2091907T3 (pt) |
GR (1) | GR3020513T3 (pt) |
HU (1) | HUT59166A (pt) |
PT (1) | PT96135B (pt) |
WO (1) | WO1991009056A1 (pt) |
ZA (1) | ZA909896B (pt) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HU207104B (en) * | 1991-01-25 | 1993-03-01 | Biosignal Kutato Fejlesztoe Kf | Process for producing new somatostatin analogs inhibiting tumour growth and pharmaceutical compositions comprising such compounds |
US7238340B1 (en) * | 1991-11-27 | 2007-07-03 | Cis Bio International | Monoamine, diamide, thiol-containing metal chelating agents |
CA2079896A1 (en) * | 1991-02-08 | 1992-08-09 | Arthur E. Bogden | Method of treating benign and malignant proliferative skin disease |
US5411943A (en) * | 1992-02-25 | 1995-05-02 | Biomeasure, Inc. | Hepatoma treatment with somatostatin analogs |
US5871711A (en) * | 1992-06-23 | 1999-02-16 | Diatide, Inc. | Radioactively-labeled somatostatin-derived peptides for imaging and therapeutic uses |
US5716596A (en) * | 1992-06-23 | 1998-02-10 | Diatide, Inc. | Radioactively labeled somatostatin-derived peptides for imaging and therapeutic uses |
ES2162822T3 (es) * | 1992-07-27 | 2002-01-16 | Univ Tulane | Utilizacion de octapeptidos para el tratamiento de enfermedades asociadas con el receptor de neuromedina b. |
US5569741A (en) * | 1992-07-27 | 1996-10-29 | Biomeasure, Inc. | Cyclic octapeptide neuromedin B receptor antagonists |
US5462926A (en) * | 1992-07-27 | 1995-10-31 | Biomeasure, Inc. | Neuromedin B receptor antagonists which demonstrate selectivity |
US5932189A (en) * | 1994-07-29 | 1999-08-03 | Diatech, Inc. | Cyclic peptide somatostatin analogs |
US5597894A (en) * | 1995-06-05 | 1997-01-28 | The Louisiana State University Medical Center Foundation | Multi-tyrosinated somatostatin analogs |
US5708135A (en) * | 1995-09-29 | 1998-01-13 | Biomeasure Incorporated | Cyclic peptide analogs of somatostatin |
US6262229B1 (en) | 1996-12-04 | 2001-07-17 | Biomeasure Incorporated | Somatostatin antagonists |
PT981363E (pt) | 1997-05-13 | 2003-12-31 | Conseils De Rec Appl Scient S | Somatostatina e agonistas da somatostatina para reduzir o peso corporal |
US6004928A (en) * | 1997-05-13 | 1999-12-21 | Biomeasure, Incorporated | Method of treating hyperlipidemia |
ES2216290T3 (es) * | 1997-05-13 | 2004-10-16 | Societe De Conseils De Recherches Et D'applications Scientifiques S.A.S. | Somatostatina y agonistas de la somatostatina para el tratamiento de insensibilidad a la insulina y de sindrome x. |
WO1998051330A1 (en) | 1997-05-13 | 1998-11-19 | Societe De Conseils De Recherches Et D'applications Scientifiques S.A. (S.C.R.A.S.) | Method and compositions for treating hyperlipidemia and other conditions |
EP1291022A1 (en) * | 1998-07-30 | 2003-03-12 | Societe De Conseils De Recherches Et D'applications Scientifiques S.A.S. | Methods of using lanreotide, a somatostatin analogue |
IL140837A0 (en) * | 1998-07-30 | 2002-02-10 | Sod Conseils Rech Applic | Method of using lanreotide, a somatostatin analogue |
HUP0401535A3 (en) * | 2001-03-08 | 2009-07-28 | Univ Tulane | Somatostatin antagonists and their use |
MXPA03009048A (es) * | 2001-04-09 | 2004-02-12 | Univ Tulane | Agonistas de la somatostatina. |
CA2449634C (en) | 2001-06-08 | 2011-08-02 | Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R | Somatostatin-dopamine chimeric analogs |
EP2662087A1 (en) | 2003-04-22 | 2013-11-13 | Ipsen Pharma | Somatostatin vectors |
EP3473643A1 (en) | 2008-06-12 | 2019-04-24 | Ipsen Bioinnovation Limited | Fusion proteins for use in the treatemnt of cancer |
US20110171191A1 (en) | 2008-06-12 | 2011-07-14 | Syntaxin Limited | Suppression of neuroendocrine diseases |
GB0820970D0 (en) | 2008-11-17 | 2008-12-24 | Syntaxin Ltd | Suppression of cancer |
JP6869720B2 (ja) | 2013-06-13 | 2021-05-12 | アンチセンス セラピューティクス リミテッド | 併用療法 |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4291022A (en) * | 1975-03-11 | 1981-09-22 | Sandoz Ltd. | Organic compounds |
CY1327A (en) * | 1979-11-27 | 1986-06-27 | Sandoz Ag | Novel polypeptides,processes for their production,pharmaceutical compositions comprising said polypeptides and their use |
US4328105A (en) * | 1980-02-06 | 1982-05-04 | Linde Aktiengesellschaft | Treatment of suspended solids--and adsorbable contaminant--containing liquid |
US4328135A (en) * | 1980-06-13 | 1982-05-04 | American Home Products Corporation | Octapeptides lowering growth hormone |
US4282143A (en) * | 1980-06-13 | 1981-08-04 | American Home Products Corporation | Octapeptides lowering growth hormone |
DK81082A (da) * | 1981-03-06 | 1982-09-07 | Sandoz Ag | Fremgangsmaade til fremstilling af polypeptider |
US4485101A (en) * | 1983-10-11 | 1984-11-27 | Administrators Of The Tulane Educational Fund | Peptides |
US4684620A (en) * | 1984-09-04 | 1987-08-04 | Gibson-Stephens Neuropharmaceuticals, Inc. | Cyclic polypeptides having mu-receptor specificity |
US4725577A (en) * | 1985-04-25 | 1988-02-16 | Administrators Of The Tulane Educational Fund | Biologically active lysine containing octapeptides |
US4650787A (en) * | 1985-04-25 | 1987-03-17 | Schally Andrew Victor | Biologically active octapeptides |
US4904642A (en) * | 1985-09-12 | 1990-02-27 | The Administrators Of The Tulane Educational Fund | Therapeutic somatostatin analogs |
US4853371A (en) * | 1986-06-17 | 1989-08-01 | The Administrators Of The Tulane Educational Fund | Therapeutic somatostatin analogs |
JP2568228B2 (ja) * | 1987-02-03 | 1996-12-25 | ジ・アドミニストレーターズ・オブ・ザ・ツーレイン・エデュケイショナル・ファンド | 治療用ソマトスタチンアナログ |
JP2809403B2 (ja) * | 1987-07-07 | 1998-10-08 | ジ・アドミニストレーターズ・オブ・ザ・ツーレイン・エデュケイショナル・ファンド | 治療用ソマトスタチンアナログ化合物 |
GB8813160D0 (en) * | 1988-06-03 | 1988-07-06 | Soc D Etudes Prod Chimique | Therapeutic methods |
-
1990
- 1990-12-04 HU HU912648A patent/HUT59166A/hu unknown
- 1990-12-04 DK DK91901181.7T patent/DK0457888T3/da active
- 1990-12-04 ES ES91901181T patent/ES2091907T3/es not_active Expired - Lifetime
- 1990-12-04 KR KR1019910700860A patent/KR920702854A/ko not_active Application Discontinuation
- 1990-12-04 AT AT91901181T patent/ATE140237T1/de not_active IP Right Cessation
- 1990-12-04 CA CA002046594A patent/CA2046594A1/en not_active Abandoned
- 1990-12-04 EP EP91901181A patent/EP0457888B1/en not_active Expired - Lifetime
- 1990-12-04 WO PCT/US1990/007074 patent/WO1991009056A1/en active IP Right Grant
- 1990-12-04 JP JP3501584A patent/JP2925321B2/ja not_active Expired - Lifetime
- 1990-12-04 DE DE69027767T patent/DE69027767T2/de not_active Expired - Fee Related
- 1990-12-07 PT PT96135A patent/PT96135B/pt not_active IP Right Cessation
- 1990-12-10 ZA ZA909896A patent/ZA909896B/xx unknown
-
1992
- 1992-02-21 US US07/840,621 patent/US5506339A/en not_active Expired - Lifetime
-
1996
- 1996-07-11 GR GR960401779T patent/GR3020513T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
GR3020513T3 (en) | 1996-10-31 |
JPH04505456A (ja) | 1992-09-24 |
US5506339A (en) | 1996-04-09 |
EP0457888A4 (en) | 1992-01-02 |
JP2925321B2 (ja) | 1999-07-28 |
WO1991009056A1 (en) | 1991-06-27 |
CA2046594A1 (en) | 1991-06-09 |
ZA909896B (en) | 1991-09-25 |
DE69027767D1 (de) | 1996-08-14 |
KR920702854A (ko) | 1992-10-28 |
HUT59166A (en) | 1992-04-28 |
DE69027767T2 (de) | 1997-01-02 |
DK0457888T3 (da) | 1996-08-12 |
ATE140237T1 (de) | 1996-07-15 |
PT96135B (pt) | 1998-04-30 |
EP0457888A1 (en) | 1991-11-27 |
ES2091907T3 (es) | 1996-11-16 |
EP0457888B1 (en) | 1996-07-10 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
BB1A | Laying open of patent application |
Effective date: 19910430 |
|
FG3A | Patent granted, date of granting |
Effective date: 19980107 |
|
MM3A | Annulment or lapse |
Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 20020731 Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 20020731 |