ES2036215T3 - Nuevos derivados de na n-(2,4,6-trimetoxibenzoil)-3-propil) peperidina, sus procedimientos preparacion y su aplicacion en terapeutica. - Google Patents

Nuevos derivados de na n-(2,4,6-trimetoxibenzoil)-3-propil) peperidina, sus procedimientos preparacion y su aplicacion en terapeutica.

Info

Publication number
ES2036215T3
ES2036215T3 ES198787400970T ES87400970T ES2036215T3 ES 2036215 T3 ES2036215 T3 ES 2036215T3 ES 198787400970 T ES198787400970 T ES 198787400970T ES 87400970 T ES87400970 T ES 87400970T ES 2036215 T3 ES2036215 T3 ES 2036215T3
Authority
ES
Spain
Prior art keywords
trimetoxibenzoil
peperidine
propil
therapeutics
application
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198787400970T
Other languages
English (en)
Inventor
Louis Lafon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cephalon France SAS
Original Assignee
Laboratoire L Lafon SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoire L Lafon SA filed Critical Laboratoire L Lafon SA
Application granted granted Critical
Publication of ES2036215T3 publication Critical patent/ES2036215T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

LA INVENCION TIENE COMO OBJETO LOS COMPUESTOS DE FORMULA (I) EN LA CUAL R SE SELECCIONA ENTRE LOS GRUPOS -CH2OH, -COOH Y -COOR1, SIENDO R1 UN GRUPO ALQUILO DE C1 A C4, Y SUS SALES FARMACEUTICAMENTE ACEPTABLES. ESTOS COMPUESTOS SON UTILES EN TERAPEUTICA.
ES198787400970T 1986-04-28 1987-04-27 Nuevos derivados de na n-(2,4,6-trimetoxibenzoil)-3-propil) peperidina, sus procedimientos preparacion y su aplicacion en terapeutica. Expired - Lifetime ES2036215T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8606133A FR2597864B1 (fr) 1986-04-28 1986-04-28 Nouveaux derives de la n-((trimethoxy-2,4,6-benzoyl)-3 propyl) piperidine, leurs procedes de preparation et leur application en therapeutique

Publications (1)

Publication Number Publication Date
ES2036215T3 true ES2036215T3 (es) 1993-05-16

Family

ID=9334690

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198787400970T Expired - Lifetime ES2036215T3 (es) 1986-04-28 1987-04-27 Nuevos derivados de na n-(2,4,6-trimetoxibenzoil)-3-propil) peperidina, sus procedimientos preparacion y su aplicacion en terapeutica.

Country Status (9)

Country Link
US (1) US4755522A (es)
EP (1) EP0244318B1 (es)
JP (1) JPS6322070A (es)
AT (1) ATE56206T1 (es)
CA (1) CA1293731C (es)
DE (1) DE3764701D1 (es)
ES (1) ES2036215T3 (es)
FR (1) FR2597864B1 (es)
GR (1) GR3001147T3 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3913682A1 (de) * 1989-04-26 1990-10-31 Bayer Ag 3-aryl-pyrrolidin-2,4-dione
FR2849029B1 (fr) 2002-12-20 2005-03-18 Lafon Labor Procede de preparation et formes cristallines des enantiomeres optiques du modafinil.
MX2008014450A (es) 2006-05-18 2009-03-09 Mannkind Corp Inhibidores de cinasa intracelular.
ES2601856T3 (es) * 2007-06-08 2017-02-16 Mannkind Corporation Inhibidores de la IRE-1A

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2092133B1 (es) * 1970-05-06 1974-03-22 Orsymonde
FR2101045A1 (en) * 1970-08-12 1972-03-31 Penciolelli Madeleine Omega-dialkylamino-1-(2,4,6-trialkoxy phenyl) alkan-1-ones - with vasodilator and spasmolytic activity
FR2504136A1 (fr) * 1981-04-15 1982-10-22 Lafon Labor (2,6-dimethoxy-4-hydroxyphenyl)-(3-piperidinopropyl)-cetone et ses sels d'addition, utilisation en therapeutique et procede de preparation
FR2534912B1 (fr) * 1982-10-26 1985-06-28 Lafon Labor Nouveaux derives de (2,4,6-trimethoxyphenyl) - (3-piperidinopropyl) -cetone, utilisation en therapeutique et procede de preparation

Also Published As

Publication number Publication date
JPS6322070A (ja) 1988-01-29
CA1293731C (en) 1991-12-31
US4755522A (en) 1988-07-05
EP0244318B1 (fr) 1990-09-05
FR2597864A1 (fr) 1987-10-30
GR3001147T3 (en) 1992-06-25
FR2597864B1 (fr) 1990-11-16
ATE56206T1 (de) 1990-09-15
EP0244318A1 (fr) 1987-11-04
DE3764701D1 (de) 1990-10-11

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