PT94779A - Processo para a preparacao da diamida do acido n,n-bis-(alcoxi-alquil)-piridino-2,4-dicarboxilico e de composicoes farmaceuticas que as contem - Google Patents

Processo para a preparacao da diamida do acido n,n-bis-(alcoxi-alquil)-piridino-2,4-dicarboxilico e de composicoes farmaceuticas que as contem

Info

Publication number
PT94779A
PT94779A PT94779A PT9477990A PT94779A PT 94779 A PT94779 A PT 94779A PT 94779 A PT94779 A PT 94779A PT 9477990 A PT9477990 A PT 9477990A PT 94779 A PT94779 A PT 94779A
Authority
PT
Portugal
Prior art keywords
pyridine
bis
dicarboxylic acid
alkyl
alcoxy
Prior art date
Application number
PT94779A
Other languages
English (en)
Other versions
PT94779B (pt
Inventor
Ekkehard Baader
Martin Bickel
Volkmar Gunzler-Pukall
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of PT94779A publication Critical patent/PT94779A/pt
Publication of PT94779B publication Critical patent/PT94779B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/56—Amides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C07D213/82—Amides; Imides in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Transplantation (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
PT94779A 1989-07-20 1990-07-20 Processo para a preparacao da diamida do acido n,n-bis-(alcoxi-alquil)-piridino-2,4-dicarboxilico e de composicoes farmaceuticas que as contem PT94779B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3924093A DE3924093A1 (de) 1989-07-20 1989-07-20 N,n'-bis(alkoxy-alkyl)-pyridin-2,4-dicarbonsaeurediamide, verfahren zu deren herstellung sowie deren verwendung

Publications (2)

Publication Number Publication Date
PT94779A true PT94779A (pt) 1991-03-20
PT94779B PT94779B (pt) 1997-04-30

Family

ID=6385494

Family Applications (1)

Application Number Title Priority Date Filing Date
PT94779A PT94779B (pt) 1989-07-20 1990-07-20 Processo para a preparacao da diamida do acido n,n-bis-(alcoxi-alquil)-piridino-2,4-dicarboxilico e de composicoes farmaceuticas que as contem

Country Status (26)

Country Link
EP (1) EP0409119B1 (pt)
JP (1) JPH0776213B2 (pt)
KR (1) KR0181945B1 (pt)
AT (1) ATE104280T1 (pt)
AU (1) AU624978B2 (pt)
CA (1) CA2021529C (pt)
CY (1) CY1997A (pt)
CZ (1) CZ280129B6 (pt)
DD (1) DD300429A5 (pt)
DE (2) DE3924093A1 (pt)
DK (1) DK0409119T3 (pt)
ES (1) ES2052112T3 (pt)
FI (1) FI94630C (pt)
HU (1) HU218274B (pt)
IE (1) IE64438B1 (pt)
IL (1) IL95121A (pt)
LT (1) LT3798B (pt)
LV (1) LV10430B (pt)
NO (1) NO177187C (pt)
NZ (1) NZ234563A (pt)
PL (1) PL166307B1 (pt)
PT (1) PT94779B (pt)
RU (1) RU1836350C (pt)
SK (1) SK279199B6 (pt)
UA (1) UA19056A (pt)
ZA (1) ZA905680B (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3707429A1 (de) * 1987-03-07 1988-09-15 Hoechst Ag Substituierte pyridin-2,4-dicarbonsaeure-derivate, verfahren zu ihrer herstellung, verwendung derselben sowie arzneimittel auf basis dieser verbindungen
EP0353668B1 (de) * 1988-08-04 1994-10-19 Hoechst Aktiengesellschaft Verbessertes Verfahren zur Herstellung von N,N-Bis(alkoxyalkyl)-pyridin -2,4-dicarbonsäurediamiden
DE4020570A1 (de) 1990-06-28 1992-01-02 Hoechst Ag 2,4- und 2,5-substituierte pyridin-n-oxide, verfahren zu deren herstellung sowie deren verwendung
DE4030999A1 (de) * 1990-10-01 1992-04-09 Hoechst Ag 4- oder 5-substituierte pyridin-2-carbonsaeuren, verfahren zu deren herstellung sowie deren verwendung als arzneimittel
YU9492A (sh) * 1991-02-05 1995-03-27 Hoechst Ag. 2,4- i 2,5-bis-tetrazolilni piridini i postupak za njihovo dobijanje
TW199147B (pt) * 1991-03-18 1993-02-01 Hoechst Ag
EP0541042A1 (de) * 1991-11-05 1993-05-12 Hoechst Aktiengesellschaft Pyridin-2,4- und 2,5-dicarbonsäureamide und deren Derivate, Verfahren zu ihrer Herstellung sowie deren Verwendung als Arzneimittel
TW222585B (pt) * 1992-09-11 1994-04-21 Hoechst Ag
DOP2002000332A (es) 2001-02-14 2002-08-30 Warner Lambert Co Inhibidores de piridina de metaloproteinasas de la matriz

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3432094A1 (de) 1984-08-31 1986-03-06 Hoechst Ag, 6230 Frankfurt Ester der pyridin-2,4- und -2,5- dicarbonsaeure als arzneimittel zur inhibierung der prolin- und lysinhydroxylase
DE3703962A1 (de) * 1987-02-10 1988-08-18 Hoechst Ag Pyridin-2,4- und 2,5-dicarbonsaeure-derivate, verfahren zu ihrer herstellung, verwendung derselben sowie arzneimittel auf basis dieser verbindungen
DE3703963A1 (de) 1987-02-10 1988-08-18 Hoechst Ag Pyridin-2,4- und 2,,5-dicarbonsaeure-derivate, verfahren zu ihrer herstellung, verwendung derselben, sowie arzneimittel auf basis dieser verbindungen
DE3703959A1 (de) * 1987-02-10 1988-08-18 Hoechst Ag Pyridin-2,4- und 2,5-dicarbonsaeureamide, verfahren zu ihrer herstellung, verwendung derselben sowie arzneimittel auf basis dieser verbindungen
EP0353668B1 (de) * 1988-08-04 1994-10-19 Hoechst Aktiengesellschaft Verbessertes Verfahren zur Herstellung von N,N-Bis(alkoxyalkyl)-pyridin -2,4-dicarbonsäurediamiden
DE3828140A1 (de) 1988-08-19 1990-03-01 Hoechst Ag Verbessertes verfahren zur herstellung von n,n'-bis(alkoxyalkyl)-pyridin-2,4-dicarbonsaeurediamiden sowie verwendung dieser verbindungen zur herstellung oralverabreichbarer arzneimittel
DE3826471A1 (de) 1988-08-04 1990-02-22 Hoechst Ag Verbessertes verfahren zur herstellung von n,n'-bis(alkoxyalkyl)-pyridin-2,4-dicarbonsaeurediamiden

Also Published As

Publication number Publication date
IL95121A0 (en) 1991-06-10
CZ357690A3 (en) 1995-06-14
KR0181945B1 (ko) 1999-05-01
JPH0776213B2 (ja) 1995-08-16
FI903624A0 (fi) 1990-07-18
CA2021529A1 (en) 1991-01-21
KR910002799A (ko) 1991-02-26
ES2052112T3 (es) 1994-07-01
PL166307B1 (pl) 1995-05-31
NO177187B (no) 1995-04-24
ATE104280T1 (de) 1994-04-15
IE902642A1 (en) 1991-02-27
CY1997A (en) 1997-09-05
LTIP1462A (en) 1995-05-25
NO903235L (no) 1991-01-21
LV10430A (lv) 1995-02-20
PL286132A1 (en) 1991-07-29
DK0409119T3 (da) 1994-08-08
DE59005328D1 (de) 1994-05-19
HU904549D0 (en) 1990-12-28
EP0409119A1 (de) 1991-01-23
NZ234563A (en) 1992-12-23
FI94630C (fi) 1995-10-10
CA2021529C (en) 1997-12-30
DE3924093A1 (de) 1991-02-07
DD300429A5 (de) 1992-06-11
AU624978B2 (en) 1992-06-25
LT3798B (en) 1996-03-25
HUT54653A (en) 1991-03-28
ZA905680B (en) 1991-04-24
RU1836350C (ru) 1993-08-23
IE64438B1 (en) 1995-08-09
IL95121A (en) 1994-08-26
SK357690A3 (en) 1998-07-08
PT94779B (pt) 1997-04-30
CZ280129B6 (cs) 1995-11-15
EP0409119B1 (de) 1994-04-13
NO903235D0 (no) 1990-07-19
JPH0358973A (ja) 1991-03-14
NO177187C (no) 1995-08-02
LV10430B (en) 1996-02-20
AU5914490A (en) 1991-01-24
HU218274B (en) 2000-07-28
FI94630B (fi) 1995-06-30
UA19056A (uk) 1997-12-25
SK279199B6 (sk) 1998-07-08

Similar Documents

Publication Publication Date Title
ES2128307T3 (es) Derivados de 1,4,7,10-tetraaza-ciclododecano monosustituidos en n, procedimiento para su preparacion y agentes farmaceuticos que los contienen.
IL70286A0 (en) Analogs of mevalolactone and derivatives thereof,their production and pharmaceutical compositions containing them
ES2062239T3 (es) Diamidas de acidos pirimidin-4,6-dicarboxilicos, procedimiento para su preparacion, utilizacion de las mismas, asi como medicamentos a base de estos compuestos.
PT94779A (pt) Processo para a preparacao da diamida do acido n,n-bis-(alcoxi-alquil)-piridino-2,4-dicarboxilico e de composicoes farmaceuticas que as contem
PT81890B (pt) Processo para a preparacao de composicoes herbicidas que contem um composto do tipo n-(fosfonometilglicil)-sulfonilamina
GR3023934T3 (en) New naphthalene amides and sulfonamides, process for their preparation and pharmaceutical compositions containing them
ES2039267T3 (es) Dihidropiridinamidas, procedimiento para su preparacion y su empleo en medicamentos.
ES2061532T3 (es) Derivados sustituidos de acido piridina-2,4-dicarboxilico, procedimientos para su preparacion, utilizacion de los mismos, asi como medicamentos a base de estos compuestos.
ES2082882T3 (es) Procedimiento para la fabricacion de derivados de acidos-3-amino-2-(het)aroil-acrilicos.
TR25218A (tr) DIEN üNITESININ BITISIGINDE YER ALAN VE ONU BIR UCTA BULUNAN GRUBA BIRLESTIRILEN BIR 1,2 SIKLOPROPIL HALKASINI HAIZ OLAN VE PERTISID ÖZELLIK ARZEDEN DOYMAMIS AMIDLER.
DE3854519D1 (de) Heteroaromatische Enamidderivate und ihre Verwendung als Schädlingsbekämpfungsmittel.
ATE158576T1 (de) Alpha-aryl-alpha-hydroxy-beta- imidazolinylpropionsäureamide
ATE43594T1 (de) 3-alkoxy-2-(n-pyrrolidino)-n-pyridyl-n-furyl(od r thienyl)-methyl-propylamine, ihre herstellung und diese enthaltende pharmazeutische mittel.
ES2108894T3 (es) Procedimiento para la preparacion de 5-cloroimidazoles eventualmente sustituidos en posicion 2.
DE3887611D1 (de) Butensäure-Amide, deren Salze, diese enthaltende pharmazeutische Zusammensetzungen und Verfahren zu deren Herstellung.
ES2105569T3 (es) Nuevos analogos de metabolitos de acidos grasos, su procedimiento de preparacion y composiciones farmaceuticas que los contienen.

Legal Events

Date Code Title Description
BB1A Laying open of patent application

Effective date: 19901024

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 20020731

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 20020731