PT91553A - Processo de preparacao de uma composicao contendo morfina - Google Patents
Processo de preparacao de uma composicao contendo morfinaInfo
- Publication number
- PT91553A PT91553A PT91553A PT9155389A PT91553A PT 91553 A PT91553 A PT 91553A PT 91553 A PT91553 A PT 91553A PT 9155389 A PT9155389 A PT 9155389A PT 91553 A PT91553 A PT 91553A
- Authority
- PT
- Portugal
- Prior art keywords
- composition containing
- preparation process
- containing morphine
- morphine
- inclusion
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0007—Effervescent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Compositions Of Macromolecular Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB888820327A GB8820327D0 (en) | 1988-08-26 | 1988-08-26 | New compositions of matter |
Publications (2)
Publication Number | Publication Date |
---|---|
PT91553A true PT91553A (pt) | 1990-03-08 |
PT91553B PT91553B (pt) | 1995-07-06 |
Family
ID=10642786
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT91553A PT91553B (pt) | 1988-08-26 | 1989-08-25 | Processo de preparacao de uma composicao contendo morfina |
Country Status (15)
Country | Link |
---|---|
US (1) | US5387420A (pt) |
EP (1) | EP0361680B1 (pt) |
JP (1) | JP2793280B2 (pt) |
AT (1) | ATE108329T1 (pt) |
AU (1) | AU613517B2 (pt) |
CA (1) | CA1338889C (pt) |
DE (1) | DE68916731T2 (pt) |
DK (1) | DK421189A (pt) |
ES (1) | ES2059775T3 (pt) |
GB (1) | GB8820327D0 (pt) |
HU (1) | HU206265B (pt) |
IE (1) | IE63911B1 (pt) |
NZ (1) | NZ230440A (pt) |
PT (1) | PT91553B (pt) |
ZA (1) | ZA896519B (pt) |
Families Citing this family (61)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9009473D0 (en) * | 1990-04-27 | 1990-06-20 | Beecham Group Plc | Pharmaceutical formulation |
US5302397A (en) * | 1991-11-19 | 1994-04-12 | Amsden Brian G | Polymer-based drug delivery system |
US5503846A (en) * | 1993-03-17 | 1996-04-02 | Cima Labs, Inc. | Base coated acid particles and effervescent formulation incorporating same |
IL109460A (en) | 1993-05-10 | 1998-03-10 | Euro Celtique Sa | Controlled release formulation comprising tramadol |
IL110014A (en) | 1993-07-01 | 1999-11-30 | Euro Celtique Sa | Solid controlled-release oral dosage forms of opioid analgesics |
US7740881B1 (en) | 1993-07-01 | 2010-06-22 | Purdue Pharma Lp | Method of treating humans with opioid formulations having extended controlled release |
US5879705A (en) * | 1993-07-27 | 1999-03-09 | Euro-Celtique S.A. | Sustained release compositions of morphine and a method of preparing pharmaceutical compositions |
US5891471A (en) | 1993-11-23 | 1999-04-06 | Euro-Celtique, S.A. | Pharmaceutical multiparticulates |
KR100354702B1 (ko) * | 1993-11-23 | 2002-12-28 | 유로-셀티크 소시에떼 아노뉨 | 약학조성물의제조방법및서방형조성물 |
US5843480A (en) | 1994-03-14 | 1998-12-01 | Euro-Celtique, S.A. | Controlled release diamorphine formulation |
US5607940A (en) * | 1994-07-18 | 1997-03-04 | Stephen; Robert L. | Morphine formulations for use by electromotive administration |
GB9422154D0 (en) | 1994-11-03 | 1994-12-21 | Euro Celtique Sa | Pharmaceutical compositions and method of producing the same |
US5965161A (en) | 1994-11-04 | 1999-10-12 | Euro-Celtique, S.A. | Extruded multi-particulates |
GB2307857B (en) * | 1995-12-04 | 1999-01-27 | Euro Celtique Sa | An effervescent formulation |
TWI285644B (en) | 1997-07-11 | 2007-08-21 | Toray Industries | A stable pharmaceutical composition containing a derivative of 4,5-epoxymorphinan and a water-soluble antioxidant, an oil-soluble antioxidant, a synergist, a sugar and a surfactant |
US20030118645A1 (en) * | 1998-04-29 | 2003-06-26 | Pather S. Indiran | Pharmaceutical compositions for rectal and vaginal administration |
US6974590B2 (en) | 1998-03-27 | 2005-12-13 | Cima Labs Inc. | Sublingual buccal effervescent |
US20030091629A1 (en) | 1998-03-27 | 2003-05-15 | Cima Labs Inc. | Sublingual buccal effervescent |
US6806294B2 (en) | 1998-10-15 | 2004-10-19 | Euro-Celtique S.A. | Opioid analgesic |
BRPI0015284B8 (pt) | 1999-10-29 | 2021-05-25 | Euro Celtique S/A | formulações de hidrocodona de liberação controlada |
US10179130B2 (en) | 1999-10-29 | 2019-01-15 | Purdue Pharma L.P. | Controlled release hydrocodone formulations |
KR101045144B1 (ko) | 2000-10-30 | 2011-06-30 | 유로-셀티크 소시에떼 아노뉨 | 서방성 하이드로코돈 제형 |
US20110104214A1 (en) | 2004-04-15 | 2011-05-05 | Purdue Pharma L.P. | Once-a-day oxycodone formulations |
UA81224C2 (uk) | 2001-05-02 | 2007-12-25 | Euro Celtic S A | Дозована форма оксикодону та її застосування |
US20030068356A1 (en) * | 2001-07-10 | 2003-04-10 | Pather S. Indiran | Sequential drug delivery systems |
US7776314B2 (en) | 2002-06-17 | 2010-08-17 | Grunenthal Gmbh | Abuse-proofed dosage system |
DE102005005446A1 (de) * | 2005-02-04 | 2006-08-10 | Grünenthal GmbH | Bruchfeste Darreichungsformen mit retardierter Freisetzung |
DE10336400A1 (de) | 2003-08-06 | 2005-03-24 | Grünenthal GmbH | Gegen Missbrauch gesicherte Darreichungsform |
US20070048228A1 (en) | 2003-08-06 | 2007-03-01 | Elisabeth Arkenau-Maric | Abuse-proofed dosage form |
DE10361596A1 (de) | 2003-12-24 | 2005-09-29 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform |
DE102004020220A1 (de) * | 2004-04-22 | 2005-11-10 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten, festen Darreichungsform |
BRPI0418213A (pt) * | 2003-12-31 | 2007-04-27 | Cima Labs Inc | forma de dosagem, e, método para tratar dor em um paciente em necessidade do mesmo |
US7858121B2 (en) | 2003-12-31 | 2010-12-28 | Cima Labs, Inc. | Effervescent oral fentanyl dosage form and methods of administering fentanyl |
JP2007517054A (ja) | 2003-12-31 | 2007-06-28 | シーマ・ラブス、インコーポレイテッド | 概して線状の発泡性経口フェンタニル投薬形態および投与方法 |
DE102004032049A1 (de) | 2004-07-01 | 2006-01-19 | Grünenthal GmbH | Gegen Missbrauch gesicherte, orale Darreichungsform |
DE102005005449A1 (de) | 2005-02-04 | 2006-08-10 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform |
CA2671197A1 (en) * | 2006-07-21 | 2008-01-24 | Lab International Srl | Hydrophobic abuse deterrent delivery system |
DE102007011485A1 (de) * | 2007-03-07 | 2008-09-11 | Grünenthal GmbH | Darreichungsform mit erschwertem Missbrauch |
EP2151241B1 (en) | 2007-04-26 | 2012-03-21 | Toray Industries, Inc. | Stable solid preparation comprising 4,5-epoxymorphinan derivative |
BRPI0906467C1 (pt) | 2008-01-25 | 2021-05-25 | Gruenenthal Gmbh | forma de dosagem farmacêutica com formato exterior modificado resistente à ruptura e com liberação controlada |
LT2273983T (lt) * | 2008-05-09 | 2016-10-25 | Grünenthal GmbH | Tarpinės miltelių kompozicijos gamybos būdas ir galutinė kieta dozavimo forma naudojant purškalo kietinimo stadija |
EP2356989B1 (en) | 2008-10-24 | 2018-02-07 | Toray Industries, Inc. | Stable tablet containing 4,5-epoxymorphinan derivative |
TW201105316A (en) | 2009-07-22 | 2011-02-16 | Gruenenthal Gmbh | Hot-melt extruded pharmaceutical dosage form |
KR101747156B1 (ko) * | 2009-07-22 | 2017-06-27 | 그뤼넨탈 게엠베하 | 산화-안정화된 탬퍼-내성 용량형 |
CN102821757B (zh) * | 2010-02-03 | 2016-01-20 | 格吕伦塔尔有限公司 | 通过挤出机制备粉末状药物组合物 |
MX2013002377A (es) | 2010-09-02 | 2013-04-29 | Gruenenthal Gmbh | Forma de dosificacion resistente a manipulacion que comprende una sal inorganica. |
RU2607499C2 (ru) | 2010-09-02 | 2017-01-10 | Грюненталь Гмбх | Устойчивая к разрушению лекарственная форма, которая содержит анионный полимер |
EA201400173A1 (ru) | 2011-07-29 | 2014-06-30 | Грюненталь Гмбх | Устойчивая к разрушению таблетка, которая обеспечивает немедленное высвобождение лекарственного средства |
EA201400172A1 (ru) | 2011-07-29 | 2014-06-30 | Грюненталь Гмбх | Устойчивая к разрушению таблетка, которая обеспечивает немедленное высвобождение лекарственного средства |
JP6117249B2 (ja) | 2012-02-28 | 2017-04-19 | グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング | 薬理学的に活性な化合物および陰イオン性ポリマーを含むタンパーレジスタント剤形 |
JP6282261B2 (ja) | 2012-04-18 | 2018-02-21 | グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング | 不正使用防止および過量放出防止医薬剤形 |
US10064945B2 (en) | 2012-05-11 | 2018-09-04 | Gruenenthal Gmbh | Thermoformed, tamper-resistant pharmaceutical dosage form containing zinc |
AU2014273227B2 (en) | 2013-05-29 | 2019-08-15 | Grunenthal Gmbh | Tamper-resistant dosage form containing one or more particles |
AR096439A1 (es) | 2013-05-29 | 2015-12-30 | Gruenenthal Gmbh | Forma de dosificación resistente al uso indebido que contiene una o más partículas |
CA2917136C (en) | 2013-07-12 | 2022-05-31 | Grunenthal Gmbh | Tamper-resistant dosage form containing ethylene-vinyl acetate polymer |
JP6480936B2 (ja) | 2013-11-26 | 2019-03-13 | グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング | クライオミリングによる粉末状医薬組成物の調製 |
AU2015261060A1 (en) | 2014-05-12 | 2016-11-03 | Grunenthal Gmbh | Tamper resistant immediate release capsule formulation comprising Tapentadol |
EA201692388A1 (ru) | 2014-05-26 | 2017-05-31 | Грюненталь Гмбх | Лекарственная форма в виде множества частиц, защищенная от вызываемого этанолом сброса дозы |
MX2017013637A (es) | 2015-04-24 | 2018-03-08 | Gruenenthal Gmbh | Forma de dosificacion resistente a alteraciones con liberacion inmediata y resistencia contra la extraccion por solventes. |
ES2831179T3 (es) * | 2015-07-24 | 2021-06-07 | Evonik Operations Gmbh | Formulaciones efervescentes de aspartato de ornitina |
CA2998259A1 (en) | 2015-09-10 | 2017-03-16 | Grunenthal Gmbh | Protecting oral overdose with abuse deterrent immediate release formulations |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2211485A (en) * | 1940-08-13 | Effervescent acetyl salicylic acid | ||
US3136692A (en) * | 1961-06-30 | 1964-06-09 | Strong Cobb Arner Inc | Effervescent composition containing polyvinylpyrrolidone |
GB1241201A (en) * | 1968-07-23 | 1971-08-04 | Sterling Winthrop Group Ltd | Improvements in or relating to effervescent pharmaceutical compositions |
US4332789A (en) * | 1975-12-15 | 1982-06-01 | Hoffmann-La Roche Inc. | Pharmaceutical unit dosage forms |
US4235236A (en) * | 1979-02-12 | 1980-11-25 | Alza Corporation | Device for dispensing drug by combined diffusional and osmotic operations |
US4366159A (en) * | 1981-09-08 | 1982-12-28 | Michael Richard Magruder | Nalbuphine-narcotic analgesic composition and method of producing analgesia |
JPS6165823A (ja) * | 1984-09-07 | 1986-04-04 | Kao Corp | 直腸投与製剤 |
JPS61183219A (ja) * | 1985-02-07 | 1986-08-15 | Takeda Chem Ind Ltd | 発泡組成物の製造法 |
IE59106B1 (en) * | 1985-05-31 | 1994-01-12 | Warner Lambert Co | A therapeutic effervescent composition and a method of preparing the same |
WO1986007547A1 (en) * | 1985-06-21 | 1986-12-31 | Gerhard Gergely | Process and device for handling processing material and the reaction product manufactured with the aid of the process and/or device |
GB8528195D0 (en) * | 1985-11-15 | 1985-12-18 | Boots Co Plc | Therapeutic compositions |
-
1988
- 1988-08-26 GB GB888820327A patent/GB8820327D0/en active Pending
-
1989
- 1989-08-25 EP EP89308659A patent/EP0361680B1/en not_active Expired - Lifetime
- 1989-08-25 CA CA000609385A patent/CA1338889C/en not_active Expired - Fee Related
- 1989-08-25 HU HU894417A patent/HU206265B/hu not_active IP Right Cessation
- 1989-08-25 DK DK421189A patent/DK421189A/da not_active Application Discontinuation
- 1989-08-25 AU AU40810/89A patent/AU613517B2/en not_active Ceased
- 1989-08-25 NZ NZ230440A patent/NZ230440A/xx unknown
- 1989-08-25 JP JP1217608A patent/JP2793280B2/ja not_active Expired - Fee Related
- 1989-08-25 ZA ZA896519A patent/ZA896519B/xx unknown
- 1989-08-25 PT PT91553A patent/PT91553B/pt not_active IP Right Cessation
- 1989-08-25 ES ES89308659T patent/ES2059775T3/es not_active Expired - Lifetime
- 1989-08-25 AT AT89308659T patent/ATE108329T1/de not_active IP Right Cessation
- 1989-08-25 IE IE274989A patent/IE63911B1/en not_active IP Right Cessation
- 1989-08-25 DE DE68916731T patent/DE68916731T2/de not_active Expired - Fee Related
-
1993
- 1993-01-08 US US08/002,514 patent/US5387420A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
HUT53521A (en) | 1990-11-28 |
ATE108329T1 (de) | 1994-07-15 |
DE68916731D1 (de) | 1994-08-18 |
EP0361680A3 (en) | 1990-04-11 |
AU4081089A (en) | 1990-03-01 |
US5387420A (en) | 1995-02-07 |
IE63911B1 (en) | 1995-06-14 |
JP2793280B2 (ja) | 1998-09-03 |
EP0361680B1 (en) | 1994-07-13 |
DK421189D0 (da) | 1989-08-25 |
ES2059775T3 (es) | 1994-11-16 |
HU206265B (en) | 1992-10-28 |
JPH02160719A (ja) | 1990-06-20 |
IE892749L (en) | 1990-02-26 |
GB8820327D0 (en) | 1988-09-28 |
ZA896519B (en) | 1990-05-30 |
PT91553B (pt) | 1995-07-06 |
DK421189A (da) | 1990-02-27 |
CA1338889C (en) | 1997-02-04 |
AU613517B2 (en) | 1991-08-01 |
DE68916731T2 (de) | 1994-12-15 |
EP0361680A2 (en) | 1990-04-04 |
NZ230440A (en) | 1990-10-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM3A | Annulment or lapse |
Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 19970831 |