GB1241201A - Improvements in or relating to effervescent pharmaceutical compositions - Google Patents

Improvements in or relating to effervescent pharmaceutical compositions

Info

Publication number
GB1241201A
GB1241201A GB3506068A GB3506068A GB1241201A GB 1241201 A GB1241201 A GB 1241201A GB 3506068 A GB3506068 A GB 3506068A GB 3506068 A GB3506068 A GB 3506068A GB 1241201 A GB1241201 A GB 1241201A
Authority
GB
United Kingdom
Prior art keywords
effervescent
pharmaceutical compositions
phenol
composition
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB3506068A
Inventor
James Richard Hargreaves
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham SWG Ltd
Original Assignee
Sterling Winthrop Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sterling Winthrop Group Ltd filed Critical Sterling Winthrop Group Ltd
Priority to GB3506068A priority Critical patent/GB1241201A/en
Priority to IE101869A priority patent/IE33495B1/en
Priority to DE19691937133 priority patent/DE1937133C3/en
Priority to FR6925150A priority patent/FR2013552A1/fr
Publication of GB1241201A publication Critical patent/GB1241201A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0007—Effervescent

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

1,241,201. Effervescent pharmaceutical compositions. STERLING-WINTHROP GROUP Ltd. 22 July, 1969 [23 July, 1968], No. 35060/ 68. Heading A5B. Effervescent pharmaceutical compositions contain a pharmacologically active (particularly an analgesic and antipyretic) acyl-amino phenol, an effervescent agent and a non-toxic polyvalent metal salt of stearic acid comprising 0.001 to 0.2% 'by weight of the total composition. Al, Ca and Mg stearates are preferred, particularly magnesium distearate and aluminium mono-, di- and/or tristearate. The phenol may be N-acetyl-p-amino-phenol or an ether (e.g. p-ethoxyacetanilide) or an ester (e.g. with salicylic or acetyl salicylic acids) derivative thereof. The effervescent nature of the composition is achieved by incorporation therein of an alkali metal (e.g. Na or K) carbonate and/or bicarbonate and a polycarboxylic aliphatic acid, e.g. citric or tartaric acid. The composition may also contain sorbitol, codeine, caffeine, lauryl sulphate, a sweetening and/or flavouring agent e.g. saccharin or glutamic acid. The compositions may be in the form of tablets or granular powders.
GB3506068A 1968-07-23 1968-07-23 Improvements in or relating to effervescent pharmaceutical compositions Expired GB1241201A (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
GB3506068A GB1241201A (en) 1968-07-23 1968-07-23 Improvements in or relating to effervescent pharmaceutical compositions
IE101869A IE33495B1 (en) 1968-07-23 1969-07-22 Improvements in or relating to effervescent pharmaceutical compositions
DE19691937133 DE1937133C3 (en) 1968-07-23 1969-07-22 Use of aluminum, calcium or magnesium mono-, di- or tristearate
FR6925150A FR2013552A1 (en) 1968-07-23 1969-07-23

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB3506068A GB1241201A (en) 1968-07-23 1968-07-23 Improvements in or relating to effervescent pharmaceutical compositions

Publications (1)

Publication Number Publication Date
GB1241201A true GB1241201A (en) 1971-08-04

Family

ID=10373325

Family Applications (1)

Application Number Title Priority Date Filing Date
GB3506068A Expired GB1241201A (en) 1968-07-23 1968-07-23 Improvements in or relating to effervescent pharmaceutical compositions

Country Status (4)

Country Link
DE (1) DE1937133C3 (en)
FR (1) FR2013552A1 (en)
GB (1) GB1241201A (en)
IE (1) IE33495B1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4265847A (en) 1978-03-30 1981-05-05 Kirby Pharmaceuticals Ltd Tabletting process

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1463505A (en) * 1973-11-21 1977-02-02 Nat Res Dev Pharmaceutical compositions
AU528310B2 (en) * 1978-11-16 1983-04-21 Beecham Group Plc Composition of paracetamol and metoclopramide
CA1182049A (en) * 1981-07-13 1985-02-05 Francis J. Sterbenz Apap antacid composition
GB8820327D0 (en) * 1988-08-26 1988-09-28 May & Baker Ltd New compositions of matter

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3308217A (en) * 1965-02-09 1967-03-07 Lowy Lawrence Method of granulating materials for subsequent forming into tablets

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4265847A (en) 1978-03-30 1981-05-05 Kirby Pharmaceuticals Ltd Tabletting process

Also Published As

Publication number Publication date
IE33495B1 (en) 1974-07-24
DE1937133B2 (en) 1978-07-06
DE1937133C3 (en) 1979-03-15
IE33495L (en) 1970-01-23
DE1937133A1 (en) 1970-10-01
FR2013552A1 (en) 1970-04-03

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