PT81445B - Processo para a dissociacao de peptideos e proteinas na ligacao metionilo - Google Patents
Processo para a dissociacao de peptideos e proteinas na ligacao metioniloInfo
- Publication number
- PT81445B PT81445B PT81445A PT8144585A PT81445B PT 81445 B PT81445 B PT 81445B PT 81445 A PT81445 A PT 81445A PT 8144585 A PT8144585 A PT 8144585A PT 81445 B PT81445 B PT 81445B
- Authority
- PT
- Portugal
- Prior art keywords
- proteins
- metionilo
- ligation
- dissociation
- peptide
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 2
- 102000004169 proteins and genes Human genes 0.000 title abstract 2
- 108090000623 proteins and genes Proteins 0.000 title abstract 2
- 238000010494 dissociation reaction Methods 0.000 title 1
- 230000005593 dissociations Effects 0.000 title 1
- 238000003776 cleavage reaction Methods 0.000 abstract 1
- QPJDMGCKMHUXFD-UHFFFAOYSA-N cyanogen chloride Chemical compound ClC#N QPJDMGCKMHUXFD-UHFFFAOYSA-N 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 230000007017 scission Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/12—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by hydrolysis, i.e. solvolysis in general
- C07K1/126—Aminolysis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/12—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by hydrolysis, i.e. solvolysis in general
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/81—Carrier - bound or immobilized peptides or proteins and the preparation thereof, e.g. biological cell or cell fragment as carrier
- Y10S530/812—Peptides or proteins is immobilized on, or in, an organic carrier
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Life Sciences & Earth Sciences (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Saccharide Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19843440988 DE3440988A1 (de) | 1984-11-09 | 1984-11-09 | Verfahren zur spaltung von peptiden und proteinen an der methionyl-bindung |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT81445A PT81445A (de) | 1985-12-01 |
| PT81445B true PT81445B (pt) | 1987-12-30 |
Family
ID=6249917
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT81445A PT81445B (pt) | 1984-11-09 | 1985-11-07 | Processo para a dissociacao de peptideos e proteinas na ligacao metionilo |
Country Status (15)
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4745178A (en) * | 1987-04-22 | 1988-05-17 | Eli Lilly And Company | Process for selective peptide bond cleavage using sulfoxides and CF3 CO |
| DE3726655A1 (de) * | 1987-08-11 | 1989-02-23 | Hoechst Ag | Verfahren zur isolierung basischer proteine aus proteingemischen, welche solche basischen proteine enthalten |
| US4945157A (en) * | 1988-05-27 | 1990-07-31 | University Of Florida | Novel Extraction procedure for protein G |
| SK279686B6 (sk) * | 1990-09-05 | 1999-02-11 | Hoechst Aktiengesellschaft | Spôsob hydrolýzy reťazca aminokyselín preproinzulí |
| EP0821006B1 (de) | 1996-07-26 | 2004-04-21 | Aventis Pharma Deutschland GmbH | Insulinderivate mit erhöhter Zinkbindung |
| DE19726167B4 (de) | 1997-06-20 | 2008-01-24 | Sanofi-Aventis Deutschland Gmbh | Insulin, Verfahren zu seiner Herstellung und es enthaltende pharmazeutische Zubereitung |
| DE19825447A1 (de) | 1998-06-06 | 1999-12-09 | Hoechst Marion Roussel De Gmbh | Neue Insulinanaloga mit erhöhter Zinkbildung |
| DE10114178A1 (de) | 2001-03-23 | 2002-10-10 | Aventis Pharma Gmbh | Zinkfreie und zinkarme Insulinzubereitungen mit verbesserter Stabilität |
| DE10227232A1 (de) | 2002-06-18 | 2004-01-15 | Aventis Pharma Deutschland Gmbh | Saure Insulinzubereitungen mit verbesserter Stabilität |
| US7193035B2 (en) * | 2002-10-29 | 2007-03-20 | Sanofi-Aventis Deutschland Gmbh | Crystals of insulin analogs and processes for their preparation |
| CN102159588B (zh) | 2008-08-07 | 2015-09-02 | 拜康有限公司 | 一种用于制备胰岛素化合物的方法 |
| NZ592283A (en) | 2008-10-17 | 2012-09-28 | Sanofi Aventis Deutschland | Combination of an insulin and the GLP-1 agonist AVE0010 |
| CN107308442B (zh) | 2009-11-13 | 2022-10-18 | 赛诺菲-安万特德国有限公司 | 包含glp-1激动剂、胰岛素和甲硫氨酸的药物组合物 |
| DK2498801T3 (en) | 2009-11-13 | 2018-05-07 | Sanofi Aventis Deutschland | PHARMACEUTICAL COMPOSITION INCLUDING desPro36Exendin-4 (1-39) -Lys6-NH2 AND METHIONIN |
| BR112013004756B1 (pt) | 2010-08-30 | 2020-04-28 | Sanofi Aventis Deutschland | uso de ave0010 para a fabricação de um medicamento para o tratamento da diabetes melito tipo 2 |
| US9821032B2 (en) | 2011-05-13 | 2017-11-21 | Sanofi-Aventis Deutschland Gmbh | Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin |
| JP6367115B2 (ja) | 2011-08-29 | 2018-08-01 | サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | ２型糖尿病患者の血糖コントロールに使用する組合せ医薬 |
| TWI559929B (en) | 2011-09-01 | 2016-12-01 | Sanofi Aventis Deutschland | Pharmaceutical composition for use in the treatment of a neurodegenerative disease |
| US9950039B2 (en) | 2014-12-12 | 2018-04-24 | Sanofi-Aventis Deutschland Gmbh | Insulin glargine/lixisenatide fixed ratio formulation |
| TWI748945B (zh) | 2015-03-13 | 2021-12-11 | 德商賽諾菲阿凡提斯德意志有限公司 | 第２型糖尿病病患治療 |
| TW201705975A (zh) | 2015-03-18 | 2017-02-16 | 賽諾菲阿凡提斯德意志有限公司 | 第２型糖尿病病患之治療 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE337223B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * | 1967-05-23 | 1971-08-02 | Pharmacia Ab | |
| US3935072A (en) * | 1972-08-10 | 1976-01-27 | Tanabe Seiyaku Co., Ltd. | Purification of coenzyme A |
| US3876501A (en) * | 1973-05-17 | 1975-04-08 | Baxter Laboratories Inc | Binding enzymes to activated water-soluble carbohydrates |
| US3919049A (en) * | 1974-06-27 | 1975-11-11 | Tokyo Tanabe Co | Process for preparing {62 -galactosidase |
| SE8302758L (sv) * | 1983-05-17 | 1984-11-18 | Pharmacia Ab | Sett for uppspjelkning av disulfidbindningar och derigenom erhallen forening |
| GB8317697D0 (en) * | 1983-06-29 | 1983-08-03 | Shell Int Research | Dissolution of peptides in non-aqueous and mixed non-aqueous/aqueous solvents |
| US4496689A (en) * | 1983-12-27 | 1985-01-29 | Miles Laboratories, Inc. | Covalently attached complex of alpha-1-proteinase inhibitor with a water soluble polymer |
-
1984
- 1984-11-09 DE DE19843440988 patent/DE3440988A1/de not_active Withdrawn
-
1985
- 1985-10-31 DE DE8585113857T patent/DE3585078D1/de not_active Expired - Fee Related
- 1985-10-31 EP EP85113857A patent/EP0180920B1/de not_active Expired - Lifetime
- 1985-10-31 AT AT85113857T patent/ATE71109T1/de not_active IP Right Cessation
- 1985-11-07 GR GR852693A patent/GR852693B/el unknown
- 1985-11-07 US US06/795,920 patent/US4644057A/en not_active Expired - Lifetime
- 1985-11-07 PT PT81445A patent/PT81445B/pt not_active IP Right Cessation
- 1985-11-07 ES ES548617A patent/ES8701780A1/es not_active Expired
- 1985-11-07 FI FI854383A patent/FI85494C/fi not_active IP Right Cessation
- 1985-11-08 JP JP60249148A patent/JPH0714960B2/ja not_active Expired - Lifetime
- 1985-11-08 DK DK516485A patent/DK166546C/da not_active IP Right Cessation
- 1985-11-08 AU AU49713/85A patent/AU580348B2/en not_active Ceased
- 1985-11-08 ZA ZA858603A patent/ZA858603B/xx unknown
- 1985-11-08 CA CA000494971A patent/CA1247081A/en not_active Expired
- 1985-11-08 IE IE279585A patent/IE58683B1/en not_active IP Right Cessation
- 1985-11-09 KR KR1019850008387A patent/KR930007428B1/ko not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| FI85494B (fi) | 1992-01-15 |
| JPH0714960B2 (ja) | 1995-02-22 |
| KR860003832A (ko) | 1986-06-13 |
| DE3585078D1 (de) | 1992-02-13 |
| US4644057A (en) | 1987-02-17 |
| FI854383L (fi) | 1986-05-10 |
| FI85494C (fi) | 1992-04-27 |
| ES8701780A1 (es) | 1986-12-01 |
| JPS61115096A (ja) | 1986-06-02 |
| DK516485D0 (da) | 1985-11-08 |
| CA1247081A (en) | 1988-12-20 |
| IE58683B1 (en) | 1993-11-03 |
| PT81445A (de) | 1985-12-01 |
| IE852795L (en) | 1986-05-09 |
| FI854383A0 (fi) | 1985-11-07 |
| DK166546B (da) | 1993-06-07 |
| EP0180920B1 (de) | 1992-01-02 |
| ZA858603B (en) | 1986-07-30 |
| EP0180920A3 (en) | 1989-01-04 |
| ATE71109T1 (de) | 1992-01-15 |
| EP0180920A2 (de) | 1986-05-14 |
| AU4971385A (en) | 1986-05-15 |
| DK166546C (da) | 1993-10-25 |
| GR852693B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1986-03-10 |
| AU580348B2 (en) | 1989-01-12 |
| KR930007428B1 (ko) | 1993-08-10 |
| ES548617A0 (es) | 1986-12-01 |
| DE3440988A1 (de) | 1986-07-10 |
| DK516485A (da) | 1986-05-10 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| PT81445B (pt) | Processo para a dissociacao de peptideos e proteinas na ligacao metionilo | |
| PT89961A (pt) | Processo para a preparacao de n-carboxianidridos de aminoacidos protegidos por uretano | |
| FI864427A7 (fi) | Menetelmä polypeptidin valmistamiseksi, joka on komplementaarinen ainakin osalle alkuperäistä peptidiä tai proteiinia, ja komplementaarisen polypeptidin käyttö | |
| ATE105867T1 (de) | Immunaffinitäts-reinigungssystem. | |
| ES2113865T3 (es) | Gen pnc humano y proteina precursora. | |
| GB2246783B (en) | Fusion proteins containing n-terminal fragments of human serum albumin | |
| DE69434520D1 (de) | Biotinylierung von proteinen | |
| DK532184D0 (da) | Antigene aminosyresekvenser | |
| EA200001071A1 (ru) | Способ получения полимер-связанных циклических пептидов | |
| DE69227041D1 (de) | Expression und reinigung von rekombinantem, löslichem gewebefaktor | |
| ES2087323T3 (es) | Metodo para producir peptidos exentos de cisteina. | |
| ES550943A0 (es) | Un procedimiento para preparar una proteina de fusion derivada de la secuencia de aminoacidos de la preprorrelaxina humana. | |
| ES2184728T3 (es) | Proteinas de union a la fibronectina. | |
| DE69434413D1 (de) | Fusionsproteine zwischen antigene aminosäuresequenzen und beta - 2- mikroglobulin | |
| PT81991B (pt) | Processo para a preparacao de derivados peptidicos, analogos a pepestatina, inibidores darenina e das proteases acidas | |
| FI851508A7 (fi) | Syklopropaaniaminohappojen ja peptidien synteesi. | |
| DE69029377D1 (de) | Substituierungsanaloge von magaininpeptiden | |
| MX167236B (es) | Peptidos sinteticos de timosina -1 y metodo para su obtencion | |
| FI943218L (fi) | Kaseinomakropeptidin peptidit, mainittujen peptidien vasta-aineet ja käytöt | |
| DE3873273D1 (de) | Verfahren zur selektiven spaltung von fusionsproteinen. | |
| DE3568298D1 (en) | Process for hydrolysis of peptide or protein | |
| PT90225A (pt) | Processo para a preparacao de proteinas que se iniciam com prolina na extremidade n-terminal |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM3A | Annulment or lapse |
Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 20021231 |